이식 신의 사구체 여과율 측정에서 정확한 감쇄 보정을 위한 신장 깊이 대표값 설정

오순남,김성훈,나성은,정용안,이성용,유이령,손형선,정수교 대한핵의학회 2002 핵의학 분자영상 Vol.36 No.4

http://www.haansoft.com/cgi-bin/matroom3_0/mat_view.pl?idx=9418&matid=10Purpose: To measure reliable glomerular filtration rate by using the representative values of transplanted renal depths, which are measured with ultrasonography. Materials and Methods: We included 54 patients (26 men, 28 women), with having both renal scintigraphy and ultrasonography after renal transplantation. We measured GFR with Gates' method using the renal depth measured by ultrasonography, and median and mean ones in each patient. We compared GFR derived from ultrasonography-measured renal depth with GFR derived from median and mean renal depths. The correlation coefficients were obtained among GFR derived from ultrasonography-measured renal depths, median and mean renal depths under linear regression analysis. We determined whether GFR derived from median or mean renal depth could substitute GFR derived from ultrasonography-measured renal depth with Bland-Altman method. We analyze the expected errors of the GFR using representative renal depth in terms of age, sex, weight, height, creatinine value, and body surface. Results: The trasplanted renal depths range from 3.20 cm to 5.96 cm. The mean value and standard deviation of renal depths measured by ultrasonography are 4.09±0.65 cm in men, and 4.24±.078 cm in women. The median value of renal depths measured by ultrasonography is 4.36 cm in men and 4.14 cm in women. The GFR derived from median renal depth is more consistent with GFR derived from ultrasonography-measured renal depth than GFR derived from mean renal depth. Differences of GFR derived from median and ultrasonography-measured renal depth are not significantly different in the groups classified with creatinine value, age, sex, height, weight and body surface. Conclusion: When median value is adapted as a representative renal depth, we could obtain reliable GFR in transplanted kidney simply. (Korean J Nucl Med 2002;36;271-6)

Evaluation of Optimal Combination of Commercially Available Superparamagnetic Iron Oxide Nanoparticles and Transfection Agents for Labelling of Human Mesenchymal Stem Cells

김성헌,오순남,박윤희,강원경,안국진,정수교 대한자기공명의과학회 2012 Investigative Magnetic Resonance Imaging Vol.16 No.1

Purpose : To determine the optimal combination of commercially available superparamagnetic iron oxide (SPIO) nanoparticles with transfection agents (TA). Materials and Methods: Protamine sulfate (Pro) and poly-L-lysin (PLL) were incubated with ferumoxide and ferucarbotran in human mesenchymal stem cells at various concentrations, and cellular viability were evaluated. Cellular iron uptake was qualitatively and quantitatively evaluated. Cell visibility was assessed via MR imaging and the T2-relaxation time was calculated. Results: The cellular viabilities with ferucarbotran were more significantly decreased than those with ferumoxide (p <0.05). Iron uptake with ferumoxide was significantly higher than that for those with with ferucarbotran. The T2-relaxation time was observed to be shorter with ferumoxide in comparison to those with ferucarbotran (p < 0.05). Ferumoxide at a concentration of 25 μg/ml in combination with either Pro or PLL at a concentration of 3.0 μg/ml did not adversely impact cell viability, maximized iron uptake, and exhibited a lower T2-relaxation time in comparison to other combinations. Conclusion: Stem cells with ferumoxide exhibited a higher cellular viability and iron uptake in comparison to ferucarbotran- treated stem cells. A 25 μg/ml of ferumoxide with a 3.0 μg/ml of TA is sufficient to label mesenchymal stem cells.

Inflammatory Myofibroblastic Tumor of the Bladder: Report of Two Cases

김한나,오순남,나성은,정승은,이영준,변재영,정찬권,최영진 대한영상의학회 2010 대한영상의학회지 Vol.63 No.3

Inflammatory myofibroblastic tumor (IMT) is a rare condition of unknown origin. Pathologically, the lesion is composed of myofibroblastic spindle cells accompanied by an inflammatory infiltrate of plasma cells, lymphocytes, and eosinophils. We report two cases of inflammatory myofibroblastic tumor of the bladder which showed different imaging features and was falsely diagnosed as malignant tumors. We discuss the imaging findings along with a literature review.

The Imaging Features of Desmoid Tumors: the Usefulness of Diffusion Weighted Imaging to Differentiate between Desmoid and Malignant Soft Tissue Tumors

이승백,오순남,최문형,나성은,정승은,변재영 대한자기공명의과학회 2017 Investigative Magnetic Resonance Imaging Vol.21 No.3

Purpose: To evaluate the imaging findings of desmoid tumors using various imaging modalities and to evaluate whether diffusion-weighted imaging (DWI) can help differentiate between desmoid and malignant tumors. Materials and Methods: The study included 27 patients with pathologically confirmed desmoid tumors. Two radiologists reviewed 23 computed tomography (CT), 12 magnetic resonance imaging (MRI) and 8 positron emission tomographycomputed tomography (PET-CT) scans of desmoid tumors and recorded data regarding the shape, multiplicity, size, location, degree of enhancement, and presence or absence of calcification or hemorrhage. The signal intensity of masses on T1- and T2-weighted imaging and the presence or absence of whirling or band-like low signal intensity on T2-weighted imaging were recorded. The apparent diffusion coefficient (ADC) values of the desmoid tumors in nine patients with DWIs were compared with the ADC values of 32 malignant tumors. The maximum standardized uptake value (SUVmax) on PET-CT images was measured in 8 patients who underwent a PET-CT. Results: The mean size of the 27 tumors was 6.77 cm (range, 2.5-26 cm) and four tumors exhibited multiplicity. The desmoid tumors were classified by shape as either mass forming (n = 18), infiltrative (n = 4), or combined (n = 5). The location of the tumors was either intra-abdominal (n = 15), within the abdominal wall (n = 8) or extra-abdominal (n = 4). Among the 27 tumors, 21 showed moderate to marked enhancement and 22 showed homogeneous enhancement. Two tumors showed calcifications and one displayed hemorrhage. Eleven of the 12 MR T2-weighted images showed whirling or band-like low signal intensity areas in the mass. The mean ADC value of the desmoid tumors (1493 × 10-6 mm2/s) was significantly higher than the mean of the malignant soft tissue tumors (873 × 10-6 mm2/s, P < 0.001). On the PET-CT images, all tumors exhibited an intermediate SUVmax (mean, 3.7; range, 2.3-4.5). Conclusion: Desmoids tumors showed homogenous, moderate to marked enhancement on CT and MRI scans and a characteristic whirling or band-like pattern on T2-weighted images. DWI can be useful for the differentiation of desmoid tumors from malignant soft tissue tumors

Alveolar Soft Part Sarcoma Arising from the Kidney: Imaging and Clinical Features

김정명,임수아,오순남,정낙균 대한영상의학회 2014 Korean Journal of Radiology Vol.15 No.3

Alveolar soft part sarcoma (ASPS) is an extremely rare malignant soft tissue sarcoma primarily affecting young patients. It usually occurs in the lower extremities, although it can occur in soft tissue anywhere in the body. However, to our knowledge, there has been no case of primary ASPS originating from the kidney in the literature. We herein present the imaging and clinical features of an ASPS which occurred in a 16-year-old male presented as a palpable mass in the left side of the abdomen.

Imaging Findings of Intrahepatic Bile Duct Adenoma (Peribiliary Gland Hamartoma): a Case Report and Literature Review

김유성,나성은,오순남,정승은,신유리,최병길,변재영,정은선,김동구 대한영상의학회 2010 Korean Journal of Radiology Vol.11 No.5

Intrahepatic bile duct adenoma is a rare benign epithelial hepatic tumor derived from bile duct cells. We report the imaging findings of a patient with bile duct adenoma, which appeared as a small heterogeneously enhancing mass with focal small cystic change on CT and MRI. Follow-up images at seven months showed a slight increase in tumor size, which could be partly explained by intratumoral hemorrhage on pathologic examination. Although rare, bile duct adenoma should be considered as a differential diagnosis of a small hypervascular tumor located in the periphery of liver. Focal cystic change and intratumoral hemorrhage may occur.

에스결장암에 의한 다발성 간 및 폐전이가 있는 환자에서 bevacizumab-FOLFIRI 항암화학요법 시행 후 전이병소의 절제술을 시행한 증례

김형진,김수홍,오순남,이상철,이윤석,강원경,김동구,오승택 대한임상종양학회 2007 대한임상종양연구 심포지엄 Vol.2007 No.12

에스결장암에 의한 다발성 간 및 폐전이가 있는 환자에서 bevacizumab-FOLFIRI 항암화학요법 시행 후 전이병소의 절제술을 시행한 증례

김형진,김수홍,오순남,이상철,이윤석,강원경,김동구,오승택 대한종양외과학회 2007 대한임상종양학회 학술대회지 Vol.2007 No.9

Imaging Findings of Midgut Volvulus Associated with a Large Small-Bowel Diverticulum in an Adult Patient: Case Report

김지영,나성은,오순남,황보설,변재영 대한영상의학회 2004 대한영상의학회지 Vol.50 No.5

Although most patients with jejunoileal diverticulum are asymptomatic, a large, small-bowel diverticulum can be associated with midgut volvulus in an adult. We present a rare case of midgut volvulus that was associated with a large, small-bowel diverticulum in a 77-year-old woman presenting with chronic recurrent abdominal pain. The CT showed the characteristic whirl sign of twisted mesentery, the small bowel loops along the superior mesenteric artery and a large sac-like small-bowel diverticulum. A small bowel series also demonstrated a corkscrew appearance of proximal jejunum, a finding suggestive of midgut volvulus, and a large jejunal diverticulum. During the laparotomy, the small bowel was seen twisted counterclockwise 270°. The mesenteric root was very shortened. A 4 cm sized diverticulum was seen on the mesenteric border of jejunum, on the portion about 40 cm distal from the Treitz ligament. 대부분의 소장 게실은 증상이 없지만 성인에서 발견되는 커다란 소장 게실은 중장 염전과 동반될 수 있다. 저자들은 만성 재발성 복통을 호소하는 77세 여자에서 발생한 커다란 소장 게실과 동반된 중장 염전의 드문 증례를 보고하고자 한다. 전산화단층촬영에서 상장간막 동맥을 따라 꼬인 장간막과 소장의 특징적인 와류증후(whirl sign)와 커다란 낭 모양의 소장 게실이 보였다. 소장조영술(small bowel series)에서도 중장 염전을 시사하는 소견인 근위부 공장의 코르크 따개 모양(corkscrew appearance)과 커다란 공장 게실이 보였다. 수술시 소장은 반시계방향으로 270°돌아있었고 장간막의 기저부는 매우 짧았다. 약 4 cm 크기의 게실이 트라이츠 인대(Treitz ligament) 40 cm 하방의 공장에서 발견되었다.

Ultrasonographic findings of low-grade endometrial stromal sarcoma of the uterus with a focus on cystic degeneration

박가은,나성은,오순남,이아원,이근호,김미란 대한초음파의학회 2016 ULTRASONOGRAPHY Vol.35 No.2

Purpose: The goal of this study was to perform a retrospective analysis of the ultrasonographicfindings associated with low-grade endometrial stromal sarcoma. Methods: Ten pathologically confirmed cases of low-grade endometrial stromal sarcoma atour institution from January 2007 to April 2014 were retrospectively reviewed. All patientsunderwent a preoperative transvaginal ultrasound. Two radiologists came to a consensusregarding the location, size, margin, and echogenicity of the tumor, as well as the presence ofintratumoral cystic degeneration and its extent and configuration. Results: Low-grade endometrial stromal sarcoma manifested as an intramural mass protrudinginto the endometrial cavity (n=6) or as a purely intramural mass (n=4). The maximal diameterof the lesion ranged from 4 to 9.1 cm (mean, 6.2 cm). The imaging features of low-gradeendometrial stromal sarcoma were variable: six cases involved predominantly solid massescontaining cystic degeneration, one was a predominantly unilocular cystic mass, two were illdefinedinfiltrative solid masses, and one was a well-defined solid mass. Among the seven caseswith internal cystic degeneration, five patients showed a multiseptated cystic area or a cysticarea with multiple small clusters, while a unilocular cystic area within the tumor was found intwo patients. Conclusion: Low-grade endometrial stromal sarcoma is associated with variable ultrasonographicfindings with regard to the location, margin, and configuration of the lesion. Multiseptated cysticareas and multiple small areas of cystic degeneration are common.