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Calcifying Aponeurotic Fibroma of the Elbow - A Case Report -
오미혜,조현득,박용구,정은아,이지혜,한종규 대한병리학회 2009 Journal of Pathology and Translational Medicine Vol.43 No.1
Calcifying aponeurotic fibroma is a rare soft tissue tumor that mostly occurs in the distal extremities of children and adolescents. We report here on a case of calcifying aponeurotic fibroma of the right elbow in an 8-year-old boy, and the tumor was diagnosed by surgical excision. The patient complained of painless swelling and mild limitation of the range of motion of the elbow joint. Radiologically, the mass was ill-defined and showed stippled calcification with shallow bony erosion. Microscopically, the tumor was composed of spindle cells with nodular deposits of hyalination and calcification, and these deposits were surrounded by palisading polygonal plump cells. Immunohistochemically, the tumor showed a diffuse positive expression for CD99 and negativity for smooth muscle actin, S-100 protein and CD34. The patient has been well with no signs of recurrence during the 42 months after surgery. Calcifying aponeurotic fibroma is a rare soft tissue tumor that mostly occurs in the distal extremities of children and adolescents. We report here on a case of calcifying aponeurotic fibroma of the right elbow in an 8-year-old boy, and the tumor was diagnosed by surgical excision. The patient complained of painless swelling and mild limitation of the range of motion of the elbow joint. Radiologically, the mass was ill-defined and showed stippled calcification with shallow bony erosion. Microscopically, the tumor was composed of spindle cells with nodular deposits of hyalination and calcification, and these deposits were surrounded by palisading polygonal plump cells. Immunohistochemically, the tumor showed a diffuse positive expression for CD99 and negativity for smooth muscle actin, S-100 protein and CD34. The patient has been well with no signs of recurrence during the 42 months after surgery.
사회적 지지 프로그램이 노인장기요양 재가급여 노인 수급자가족원의 부담감에 미치는 효과
오미혜,박경민 한국지역사회간호학회 2014 지역사회간호학회지 Vol.25 No.2
Purpose: This study was conducted to evaluate the effect of a social support program on family caregivers’ rolestrain in elderly long-term home care. Methods: The research adopted a non-equivalent control group pretest-posttest design. The number of participants was 25 in the experimental group and 25 in the control groupsampled among family caregivers in elderly long-term home care. The experimental group participated in a10-session social support program, which consisted of physical, emotional, informational, and material support. The effect of the program was evaluated by measuring family caregivers’ role strain. Results: The experimentalgroup showed a significant decrease in family caregivers’ role strain in elderly long-term home care. Conclusion:The result suggests that the social support program was effective in decreasing family caregivers’ role strain inelderly long-term home care. There is a need to develop more effective and systematicsocial support programsforfamily caregivers of elderly long-term home care
오미혜,정혜연,조현득,정진행,배상병,이지혜,장시형,이현주 대한병리학회 2015 Journal of Pathology and Translational Medicine Vol.49 No.4
Thymic carcinomas are uncommon malignant tumors, and thymic adenocarcinomas are extremely rare. Here, we describe a case of primary thymic adenocarcinoma in a 59-year-old woman. Histological examination of the tumor revealed tubular morphology with expression of cytokeratin 20 and caudal-type homeobox 2 according to immunohistochemistry, suggesting enteric features. Extensive clinical and radiological studies excluded the possibility of an extrathymic primary tumor. A review of the literature revealed only two global cases of primary tubular adenocarcinomas of the thymus with enteric immunophenotype.
대퇴부의 횡문근내에서 발생한 과립세포 종양의 세침흡인 세포학적 소견 - 1 증례 보고 -
오미혜,강신광,Oh, Mee-Hye,Khang, Shin-Kwang 대한세포병리학회 1993 대한세포병리학회지 Vol.4 No.1
Granular cell tumor is mostly benign and thought to be of Schwann ceil origin. The head and neck, particularly tongue, breast, and upper respiratory tract are frequently involved. Recently, we have experienced a case of granular cell tumor of the right thigh in a 30-year old male, diagnosed by fine needle aspiration cytology which revealed distinct cytologic features The smear revealed cellular aspirates with clear back-ground. The tumor cells showed uniform small nuclei and abundant eosinophilic, granular cytoplasm with hazy cell border. Mitoses were not found.
Clinicopathological Significance of S100A4 Expression in Non-small Cell Lung Carcinomas
오미혜,정은아,조현득,이지혜 대한병리학회 2010 Journal of Pathology and Translational Medicine Vol.44 No.5
Background : S100A4 has been implicated in invasion and metastasis of various malignant tumors. The aim of this study was to investigate whether or not S100A4 plays an important role in non-small cell lung carcinomas (NSCLCs). Methods : Sixty-seven patients with NSCLC including 37 with squamous cell carcinomas (SCCs) and 30 with adenocarcinomas (ADs) who had undergone surgical resection were analyzed. S100A4 expression was analyzed by immunohistochemistry using tissue microarray blocks. Results : S100A4 expression was positive in 56 (83.6%) of 67 NSCLC cases. ADs were more frequently S100A4 positive than SCCs (p = 0.017). However, no significant correlation was observed between S100A4 expression and age, gender, pT, pN or tumor, node and metastasis (TNM) stage. Two distant metastatic cases revealed an S100A4 positive reaction. Kaplan-Meier survival curves with the logrank test showed no correlation with 3-year survival (p = 0.782) or 5-year survival (p = 0.227) in either group of patients according to S100A4 expression. Conclusions : S100A4 expression was not correlated with age, gender, pT, pN or TNM stage or survival in patients with NSCLCs. Therefore, S100A4 expression may not be useful as a prognostic marker for NSCLCs. However, S100A4 expression showed a higher positivity in ADs than in SCCs.
오미혜,정은아,이지혜,조현득,양승하,곽정자 대한병리학회 2010 Journal of Pathology and Translational Medicine Vol.44 No.6
We report a case of spindle cell epithelioma, a so-called benign mixed tumor of the vagina. The patient was a 35-year-old nulliparous woman who presented with a polypoid mass in the posterior wall of the lower vagina just above the hymenal ring. The tumor was relatively welldefined with an expansile margin and composed of stromal-type spindle cells with a myxoid stroma arranged in short fascicles and an irregular cord-like or reticular pattern. A few glandular structures lined by cuboidal cells with squamous metaplasia were also noted. Cellular atypia was not conspicuous and mitosis was not found. We examined this tumor immunohistochemically to identify the histogenesis. The coexpression of epithelial and mesenchymal markers in stromal-type spindle cells suggested a multipotential cell origin for this tumor. The patient has been well with no signs of recurrence during the 12 months after surgery.