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      • KCI등재

        정상성인의 인솔 높이가 균형에 미치는 영향

        오명화 ( Myoung Hwa Oh ),이전형 ( Jeon Hyeong Lee ),권유정 ( Yoo Jung Kwon ),이종대 ( Jong Dae Lee ),이명희 ( Myoung Hee Lee ),김경 ( Kyung Kim ) 대한물리의학회 2009 대한물리의학회지 Vol.4 No.2

        Purpose:The purpose of this study was to investigated the effect of stability on heel-heights of insole in healthy adults. Methods:Subjects of 39 males measured stability index of the Biodex Stability System(BSS) by wearing shoes of 2cm, 5cm insoles including bare feet. The BSS was consisted of a movable balance platform and the platform was interfaced with computer software that enables the device to serve as an assessment of balance performance. Stability index of the BSS included overall stability index(OSI), anteroposterior stability index (APSI), mediolateral stability index(MLSI). In the BSS, subjects were asked to step on to the platform of the BSS and assume a comfortable position while maintaining slight flexion in the knees, looking straight ahead. Subjects were trained for 10min for adaptation to the heel-height of insole and then they maintained double limb stance for 2min. Biodex platform set to convert Lv.8 into Lv.1 gradually. Results:There were statistically significant differences between heel-heights of insole and stability index of OSI, APSI, and MLSI(p<.05). The result of post-hoc test were as follows; 1)OSI had significant differences between bare feet and 2cm, 5cm. 2)APSI had significant differences between bare feet and 2cm, 5cm. 3)MLSI had significant differences between bare feet and 2cm, 5cm(p<.05). Conclusions:We found that the more heels of insole high, the more stability index increases. In particular, balance index of insole above 5cm more increased and we could acknowledge that the insole above 5cm more effected balance of healthy adults.

      • KCI등재

        실험적으로 유발된 직장종양에 대한 치료적 초음파의 효과

        정미선,오명화,김계엽,김찬규,Cheong, Mee-Sun,Oh, Myoung-Hwa,Kim, Gye-Yeop,Kim, Chan-Kyu 대한물리치료과학회 2004 대한물리치료과학회지 Vol.11 No.3

        The use of therapeutic ultrasound(US) in humans with malignant neoplasms has been contra-indicated in physical therapy practice. Some studies have shown the results after application of US inhibited of tumor growth but some studies have shown the results facilitated of tumor growth in mouse. The purpose of this study were to determine the effects of US on rectal sarcoma(CT-26) in mouse and to determine the histological change of tumor. Thirty-five female BALB/C mouse, age 6 to 8 weeks received subcutaneous injection of 0.1 105 tumor cells. When tumors grew to 5 mm in diameters, the mouse were randomly assigned to control group(n=7) and high powered continuous US group(n=7) and low powered continuous US group(n=7) and high powered pulsed US group(n=7) and low powered pulsed US group(n=7). The experimental group (four groups) received 10 treatments over a 10-day period of 3 MHz ultrasound. Tumor dimension were measured on days 1(start of treatment), 5(midtreatment), and 10(end of treatment, preexcision and postexcision). Tumors were weighed after excision and the mouse were observated histological change of tumor. All tumors grew larger over time. Mean tumor weights(in grams) and volumes(in cubic millimeters) were 2.063 g and $2729.313\;mm^3$ for the high powered continuous US group 1.881 g and $2428.002\;mm^3$ for the low powered continuous US group 1.730 g and $2381.002\;mm^3$ for the high powered pulsed US 1.673 g and $2289.562\;mm^3$ for the low powered pulsed US group 1.670 g and $2297.333\;mm^3$ for the control group. Ultrasound increased the weight and volume of subcutaneous tumor in mouse. We urge caution in the use of ultrasound in the areas of tumors.

      • Streptozotocin 유발 당뇨백서에서의 골격근의 GLUT-4와 근섬유의 변화

        허명,김계엽,오명화,박승규,Heo, Myoung,Kim, Kye-Yoep,Oh, Myung-Hwa,Park, Seung-Kyu 대한임상전기생리학회 2003 대한임상전기생리학회지 Vol.1 No.1

        The purpose of this study is to discuss and analyze the change of GLUT-4 and muscle fiber type of streptozotocin(STZ)-diabetic rats over a period of 6 weeks. We divided into four groups; I(aquatic exercise and feeding of Cordyceps militaris; n=6), test group II(feeding of Cordyceps miliaris; n=6), test group III(aquatic exercise; n=6), control group IV(non-treatment; n=6). After experimenting we measured the blood glucose, body weight, muscle fiber type and GLUT-4 protein content. The change of glucose levels decreased greater in group I than the other group. The body weight gain was lower in the all groups. The change femoris muscle fiber type, the size of muscle fiber TypeII lessened more than the one of Type I in group IV. Decrease of muscle fiber size more diminishment in group I than the other group. GLUT-4 protein quantity decrease in group IV compared to normal group. It was significantly increased in group. I, III compared to group IV. But there was more increase in group I (p<.001). These results suggest that GLUT-4 and muscle fiber type II decrease in STZ-diabetic rats and that when we apply aquatic exercise and feeding of Cordyceps militaris in diabetic rats over a period 6 weeks, it is increase GLUT-4 and the increase of insulin sensitivity of peripheral tissue. So it is considered to be helpful in improvement of glucose homeostasis and in prevent from muscle atrophy resulted from complication.

      • SCOPUSKCI등재

        면역억압계군에서 Salmonella gallinarum 감염에 대한 면역반응

        김계엽,임재향,고홍범,조경오,김태열,오명화,Kim, Gye-Yeup,Lim, Jae-Hyang,Koh, Hong-Bum,Cho, Kyoung-Oh,Kim, Tae-Youl,Oh, Myoung-Hwa 대한수의학회 2002 大韓獸醫學會誌 Vol.42 No.3

        The immune response against Salmonella gallinarum infection was investigated in immunosuppresed chickens. Newly hatched chickens were treated with cyclophosphamide at the first and second day after birth and were challenged intraperitoneally with S gallinarum ($1{\times}10^7CFU/m{\ell}$) on day 6. Group 1, Immunosuppresed and Challenged group, was treated with cyclophaiphamide and challenged with S gallinarum; group 2, Immunosuppressed group, was only treated with cyclophsphamide; group 3, Challenged group, was only challenged with S gallinarum; group 4, Control group. In each group, the localization of lymphocytes of the lymphoid organs and intestine was immunohistochemically compared using a variety of monoclonal antiboies ($CD4^+$, $CD8^+$, and B lymphocyte). Also, S gallinarum were assessed by Maccallum-Goodpasture stain and immunohistochemical analysis in the paraffin-embedded intestinal tissues. In S gallinarum challenged chickens, $CD4^+$ and $CD8^+$ lymphocytes of the intestinal organs such as duodenum, jejunum, ileum and colon were increased. However, in cyclophophamide treated chickens, $CD4^+$ and $CD8^+$ lymphocytes and especially B lymphocytes of the lymphoid organs such as thymus, spleen, and bursa of Fabricius were dramatically decreased. These results suggest that cyclophsophamide is an immunosuppressive agent that especially causes depletion of B lymphocytes, suppress humoral immunity and eventually suppresses avian immune responses. Its protection against S gallinarum infection is mainly dependent on both cell-mediated mechanism and the humoral immune response.

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