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Concentration and Seasonal Variation of Particle PCBs in Air
여현구,천만영 한국대기환경학회 2005 한국대기환경학회지 Vol.21 No.E1
Atmospheric concentrations of PCBs were monitored in Ansung-city, Kyonggi province during the2001/2002 to characterize the concentration distribution and seasonal variation of particle polychlorinated-CBsand minimum value for octa-CBs. Seasonal contributions (%) of total particle PCBs showed the highestvalue in winter months and lowest value in summer month. This result indicated that concentration of totalparticle PCBs increased with decreasing temperature in the atmosphere. Therefore, particle PCBs wereeasily formed by the condensation of gas phase PCBs in winter months. The total particle PCBs exhibited an inverse correlation with temperature (p0.01) which suggestedthat particle PCBs were easily formed by condensation of gaseous PCBs in winter months.
안성 지역 소나무 잎과 토양 중 PBDEs의 농도 수준 및 특성
여현구,조기철,천만영,Yeo, Hyun-Gu,Cho, Ki-Chul,Chun, Man-Young 한국환경보건학회 2006 한국환경보건학회지 Vol.32 No.2
Polybrominated diphenyl ethers (PBDEs) in pine needles and soil samples from rural area were analyzed in this study. Concentrations of PBDE congeners were ranged between 0.2 and 3104 pg/g DW(dry weight) in pine needles and between 2.4 and 1997 pg/g DW in soil samples. The most abundant congener both in pine needles and soil samples was BDE-209, which was related to importation and production of deca-BDE technical mixtures in Korean industry. And BDE-99, BDE-47, BDE-100 deposited in pine needles and soil samples were closely matched with the major constituents of the penta-BDE technical mixture. Those can be interpreted as an evidence that transfer of the congeners in deca-BDE and penta-BDE technical mixtures from source to pine needle and soil occurs with broadly similar efficiency. Correlation coefficient(r) of PBDE congeners deposited in pine needles and soil samples is very significant because it implies th at there has been little weathering/degradation/alteration of the congeners generated from sources during atmospheric transport or within pine needles and soil themselves.
여현구,홍정주,이영전,이경식,전창엽,박정형,원진영,서진철,안유진,김건우,백승호,황은하,김그린,진영배,정강진,구본상,강필용,임경섭,김선욱,허재원,김영현,손영훈,김지수,최치훈,차상훈,이상래 한국뇌신경과학회 2019 Experimental Neurobiology Vol.28 No.4
The function of microglia/macrophages after ischemic stroke is poorly understood. This study examines the role of microglia/macrophages in the focal infarct area after transient middle cerebral artery occlusion (MCAO) in rhesus monkeys. We measured infarct volume and neurological function by magnetic resonance imaging (MRI) and non-human primate stroke scale (NHPSS), respectively, to assess temporal changes following MCAO. Activated phagocytic microglia/macrophages were examined by immunohistochemistry in post-mortem brains (n=6 MCAO, n=2 controls) at 3 and 24 hours (acute stage), 2 and 4 weeks (subacute stage), and 4, and 20 months (chronic stage) following MCAO. We found that the infarct volume progressively decreased between 1 and 4 weeks following MCAO, in parallel with the neurological recovery. Greater presence of cluster of differentiation 68 (CD68)-expressing microglia/macrophages was detected in the infarct lesion in the subacute and chronic stage, compared to the acute stage. Surprisingly, 98~99% of transforming growth factor beta (TGFβ) was found co-localized with CD68-expressing cells. CD68-expressing microglia/macrophages, rather than CD206+ cells, may exert anti-inflammatory effects by secreting TGFβ after the subacute stage of ischemic stroke. CD68+ microglia/macrophages can therefore be used as a potential therapeutic target.