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STANDARDS OUTLOOK 국내 기술표준동향 - 인증제품 구매활성화를 위한 공공기관 구매실적과 계획 조사결과
양승배,Yang, Seung-Bae 기술표준원 2011 기술표준 Vol.110 No.-
인증제품에 대한 공공기관 구매실적 조사결과 지난해 NEP 제품구매액은 약간 감소했으나, 이는 인증 제품수 감소에 따른 현상으로 NEP 제품별 평균구매액은 증가한 것으로 나타났다.
수술 전 혈소판 기능 검사를 위한 PFA<sup>®</sup>-100의 임상적 이용
김성만,양승배,이제훈,Kim, Sung-Man,Yang, Seung-Bae,Lee, Jehoon 대한임상검사과학회 2009 대한임상검사과학회지(KJCLS) Vol.41 No.1
The Platelet Function Analyzer (PFA)$^{(R)}$-100 measures the ability of platelets activated in a high-shear environment to occlude an aperture in a membrane treated with collagen and epinephrine (CEPI) or collagen and ADP (CADP). The time taken for the flow across the membrane to stop (closure time, CT) is recorded. The aim of this study was to assess the potential of the PFA$^{(R)}$-100 as a primary clinical screening tool using the wide spectrum of clinical samples assessed for platelet function as well as to perform the optimal algorithm for the use of PFA$^{(R)}$-100. We established the reference interval in 460 hospital inpatients defined as having normal platelet function based on classical laboratory tests. The reference interval by using the range $5^{th}$ and $95^{th}$ percentile was 84~251 seconds for males CEPI-CT and 85~249 seconds for females CEPI-CT. A total of 1,200 inpatients were enrolled to identify impaired hemostasis before surgical interventions. The abnormal group showing prolonged CEPI-CT was 303 cases (18.9%). Only 3 cases had both abnormal CEPI-CT and CADP-CT. Several factors including sample errors, drugs, hematologic abnoralities were contributed to unexpected prolonged CEPI-CT for screening test. The von Willebrand factor (vWF:Ag) assay was performed only in one patient to verify the algorithm for the use of PFA$^{(R)}$-100. The PFA$^{(R)}$-100 was sensitive and rapid method for primary screening test of platelet dysfunction, so we can substitute it for the bleeding time in routine clinical practice.
Signal Changes in Hippocampal Subfields during Controlled Breathing Patterns by Using Functional MRI
박찬아,양승배,이경진,이영배,김행근,강창기 한국물리학회 2019 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.74 No.7
The purpose of this study was to investigate the functional properties of each hippocampal subfield and determine its association with decreased working memory due to abnormal breathing. Eleven healthy volunteers participated in this study and performed a breathing task in magnetic resonance imaging (MRI). To quantify the effects of various breathing patterns on the hippocampus, we segmented its subfields and then applied them to the functional MRI (fMRI) data to measure the signal change according to the respiration pattern. The results indicated that mouth breathing (mouth inhalation and exhalation) had the biggest effect on signal change. Of all subfields studied, the hippocampal head showed the greatest change. These findings imply that mouth breathing can significantly induce blood oxygenation level-dependent (BOLD) signal change in the hippocampus; especially, the hippocampal head is the most susceptible to breathing alterations, suggesting that it could be strongly associated with poor working memory in habitual mouth-breathers.