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한국 재래계의 HNF4α 유전자 내 SNP와 성장과의 연관성 분석
양송이,최소영,홍민욱,김훈,곽경록,이효정,정동기,손시환,홍영호,이성진,Yang, Song-Yi,Choi, So-Young,Hong, Min-Wook,Kim, Hun,Kwak, Kyeongrok,Lee, Hyojeong,Jeong, Dong Kee,Sohn, Sea Hwan,Hong, Yeong Ho,Lee, Sung-Jin 한국가금학회 2018 韓國家禽學會誌 Vol.45 No.4
$HNF4{\alpha}$ 유전자는 인간의 지질 수송 및 대사에 관여하는 간 전사인자로써, 닭의 지방 축적에 관련된 잠재적 후보유전자로 선정하였다. 선행연구에서 보고된 $HNF4{\alpha}$ 유전자 내 A543G SNP은 외래 육계뿐만 아니라, 외래 육계와 유전적 차이를 가지는 한국 재래계의 생시체중과 생체중에 유의적 연관성을 보인 바 있으나, 해당 SNP의 정확한 위치는 보고된 바 없다. 따라서 본 연구에서는 sequencing을 통하여 A543G SNP의 정확한 위치를 파악하고, A543G SNP의 주변 부위의 한국 재래계의 산육형질에 유의적 연관성이 있는 SNP을 파악하고자 하였다. Genomic DNA는 128수의 한국재래계의 혈액을 이용하여 추출하였으며, PCR 뒤 sequencing에 사용되었다. Sequencing 결과, 증폭범위 내에서 총 14개의 SNP가 탐색되었으며, 이 중 $HNF4{\alpha}$ 유전자의 intron 4 상에서 기존에 보고되지 않은 1개의 새로운 SNP를 발견하였다. 확인된 14개의 SNP 중 rs731246957과 rs736159604가 재래계의 생시체중 및 생체중에 유의적 연관성(P<0.001)을 보였다. rs731246957은 닭의 20번 염색체의 5,566,970번째에 위치하며, 선행논문에서 체중과의 연관성이 보고된 A543G SNP인 것으로 확인되었으며, 기존의 연구결과와 유사한 결과를 얻을 수 있었다. 반면에 선행논문에서 닭의 성장형질과의 연관성이 보고된 적 없는 rs736159604 SNP는 GG 유전자형 그룹이 GA, AA 유전자형 그룹에 비해 꾸준히 높은 체중 관측치를 보였으며, 특히 40주령의 체중은 다른 유전자형 그룹에 비해 약 1.8배 높게 관측되었다. 뿐만 아니라 신규 발견한 SNP의 T allele을 가지는 계군이 G allele을 가지는 계군보다 성장면에서 고능력을 보이는 것을 확인하였다. 따라서 본 연구결과는 한국재래계의 산육형질과 연관된 후보유전자로써 $HNF4{\alpha}$ 유전자의 기초정보를 제공하며, 해당 유전자내 특정 단일염기의 변이가 재래계의 체중 관련 유전자 마커로 유용하게 활용 가능할 것을 시사한다. The hepatocyte nuclear factor 4 alpha ($HNF4{\alpha}$) gene is related to lipid transport, including abdominal fat and growth, in chickens. Interestingly, the A543G SNP within the $HNF4{\alpha}$ gene has previously been reported to be associated with body weight in both broilers and Korean native chickens (KNCs). However, its exact position within the HNF4 is not yet reported. This study aimed to identify the position of the A543G SNP and to identify additional SNPs that can be used as genetic markers in KNCs. A total of 128 KNCs were used for the sequencing and analysis of these genetic associations. As a result, A543G SNP was located in intron 4 of the $HNF4{\alpha}$ gene; it is reported as rs731246957 in the NCBI database. Fourteen SNPs were detected in the sequenced portion of the $HNF4{\alpha}$ gene; three of these, rs731246957, rs736159604 and new SNP, intron 6 (249), were significantly related with growth in the chickens. In this study, the TT genotype of rs731246957, previously reported as A543G SNP, the GG genotype of rs736159604 and GT of new SNP have are highly associated with body weight from birth to 40 weeks of age in KNCs (P<0.01). These results suggest that rs736159604, rs731246957 and intron 6 (249) SNPs within the $HNF4{\alpha}$ gene could function as growth-related markers in the selective breeding of KNCs.
반성적 사고 기반 교육연극을 활용한 예비교사 교육 프로그램 개발 및 적용
양송이(Song-Yi, Yang),조덕주(Duk-Joo, Jo) 한국문화교육학회 2020 문화예술교육연구 Vol.15 No.6
This study aimed to analyze the effects of the pre-service teacher education program based on their experiences and the their reflection using educational drama. The program including 4 main performance tasks was developed by reconstructing the content of the ‘Curriculum’ subject according to backward design and applied to an experimental group of 30 pre-service teacher for 13 weeks. To analyze the effects of this program, pre-service teachers’journals on curriculum perspectives were gathered and, in-depth interview & survey of satisfaction on this program were conducted. Analysis those results gathered showed the positive changes in aspects of the clarification of pre-service teachers’ curriculum perspectives. and in the improvement of a level of reflection as were set in the purpose of this program. And high satisfaction with this program was appeared, especially in aspects of the interaction with other teachers while they were acting in the drama. Based on this results, it was recommended the application of educational drama to other subjects and the extension of implementation period of these subjects. 본 연구는 예비교사가 실제 교육현장과 유사한 경험 및 경험에 대한 반성적 성찰을 할 수 있도록 반성적 사고 기반 교육연극 프로그램을 개발하여 적용한 후, 그 효과를 분석한 것이다. 프로그램의 목적은 예비교사들이 자신의 교육과정 관점을 명료화해 나가는 것이며, 이를 위해 교직 이론 과목인 ‘교육과정’ 과목을 대상으로 백워드 설계에 따라 교육연극을 활용한 프로그램을 개발하였다. 프로그램의 적용은 서울 K 대학교 교직이수 학생 30명의 동의를 받아 2019년 1학기 동안 수행하였고 프로그램의 효과로서 학생들의 교육과정 관점의 변화와 교육연극의 유용성에 대해 분석하였다. 연구 결과, 교육과정 관점의 변화에 있어서 예비교사들은‘나는 그런 교사가 되고 싶지 않다’라는 자신의 교육과정 관점에 대한 막연한 자각으로부터, ‘나는 어떤 교육과정 관점을 가지고 있다’라는 교육과정 관점의 명료화, 그리고‘타인과 사회의 요구 등을 고려한 교육과정 관점의 재 명료화’및‘다양한 요인을 고려한 교육과정 관점’으로 변화하는 특징을 나타냈다. 또 교육연극은 학습경험, 교수학습방법, 상호작용, 반성적 사고, 현실적 경험에 효과가 있다고 반응하였다. 이러한 연구결과는 교육연극을 활용한 예비교사 프로그램이 교육과정 관점 명료화 및 교수학습방법으로 효과적임을 나타내며 앞으로 다른 교직과목에로의 확산 및 경험을 바탕으로 한 교직과목간의 연계 등을 제안하였다.
양송이 ( Song Yi Yang ),오정민 ( Jeong Min Oh ),송다혜 ( Da Hye Song ),송보람 ( Bo Ram Song ),강명진 ( Myung Jin Kang ),이명선 ( Myung Sun Lee ),손가연 ( Ga Yeon Son ),오상환 ( Sang Hwan Oh ) 한국치위생학회(구 한국치위생교육학회) 2014 한국치위생학회지 Vol.14 No.4
Objectives : Latex gloves hygiene is the most effective method to prevent infection of microorganisms and to reduce the incidence of cross infections. The aim of this study was to compare the bacteria reduction ratio of cleansing with water, liquid soap and alcohol gauze. Methods : The left side glove was the control group and the right side was the experimental group. The experimental group washed hand with water, soap, and alcohol gauze. The hand plate was inoculated by the hand and inoculated for 24 hours in 35℃. Results : Washing with water showed that CFU of control group was 1116.9 and that of experimental group was 302.8. Hand washing by water reduced 74.3% of bacteria. Liquid soap revealed that CFU of control group was 619.9 and that of experimental group was 8.3. Hand washing by liquid soap reduced 97.5% of bacteria. Alcohol gauze included 875.2 CFU in control group and 5.8 CFU in experimental group. Washing by alcohol gauze reduced 99.5% of bacteria. Conclusions : Based on the results, the most effective latex gloves cleansing method was recommended as the standardized hand washing with the liquid hand soap and alcohol gauze. The results can be used to improve training strategies for enhancing glove hygiene practice in dental clinic.
국내 치위생(학)과 개설 현황 및 치과위생사의 활동 실태
양송이 ( Song-yi Yang ),유수민 ( Soo-min You ),이희연 ( Hee-yeon Lee ),임소현 ( So Hyeon Lim ),채주영 ( Joo-young Chae ),황선혜 ( Seon-hye Hwang ),오상환 ( Sang-hwan Oh ) 한국치위생학회 2021 한국치위생학회지 Vol.21 No.6
Objectives: Dental hygienists are an essential human resource in dental service organizations. However, there are several important persisting problems faced by them, that need to be solved. The purpose of this study was to explore the current situation in dental hygiene education institutions, number of active dental hygienists, and employment distribution across South Korea. Methods: The study gathered statistics of dental hygiene educational institutions, the ratio of active dental hygienists and the number of dental hygienists working across South Korea from officially reviewed websites. Results: Daegu and Gyeongbuk regions house the most number of colleges with dental hygiene programs. The Daejeon and Chungnam regions had the most universities with dental hygiene programs. The activity ratio of dental hygienists decreased every year. Dental hygienists’ employment was highly focused in the Seoul and Gyeonggi provinces. Conclusions: The survey data can be used as basic data for future dental hygienist education to cope with the shortage of active dental hygienists and regional imbalances. This could prove useful to consider the employment of dental hygienists appropriately.
양송이 ( Song Yi Yang ),손가연 ( Ga Yeon Son ),조미숙 ( Mi Suk Cho ),오상환 ( Sang Hwan Oh ) 한국치위생학회 2015 한국치위생학회지 Vol.15 No.4
Objectives: The purpose of the study was to investigate the awareness towards employment in the dental hygiene students. Methods: A self-reported questionnaire was completed by 425 dental hygiene students in Chungcheongdo and Gyeongsangdo from July to September, 2014. Except incomplete answer, 401 data were analyzed using SPSS 20.0 program. The questionnaire consisted of three questions of general characteristics of the subjects, nine questions of awareness towards employment, six questions of awareness of employment preparation, and eleven questions of awareness of employment outlook. Results: The dental hygiene students prefer to dental hygiene related institution including dental hospital, dental clinic, general hospital, and university hospital. The awareness for the knowledge of desired employment institution was average. The main access for the information of the employment was internet, and senior and professor’s advice, The most important preparations for the employment were a practical skill, trust, certificate, license, communication skill and English proficiency. The future outlook for the dental hygienist within five years was not optimistic, and the best way to overcome the weka point was specialization of the dental hygienist. Conclusions: This study will provide the useful information on improvement of employment strategy program for dental hygiene students.