산업재해 예방 및 대응에 있어서 기업 역할의 중요성 : 한・일 산업안전 대응체계 비교를 바탕으로

양서연 이화여자대학교 스크랜튼대학 스크랜튼학부 2023 ATE Vol.13 No.-

The Effect of Stroke on Pharyngeal Laterality During Swallowing

양서연,최경효,손유리 대한재활의학회 2015 Annals of Rehabilitation Medicine Vol.39 No.4

Objective To investigate whether patterns of dysphagia and swallowing laterality differ according to the location of brain lesions in patients with stroke.Methods Patients with stroke >20 years of age were enrolled in this study. A videofluoroscopic swallowing study (VFSS) including the anterior-posterior view was used to assess swallowing. Patterns of swallowing were classified into three types according to the width of barium sulfate flow while passing the pharyngoesophageal segment: right-side-dominant flow, left-side-dominant flow, and no laterality in flow. Laterality was defined when the width of one side was twice or more the width of the other side.Results A total of 92 patients who underwent swallowing function evaluations by VFSS were enrolled from September 2012 to May 2013. Of these, 72 patients had supratentorial lesions (group I) and 20 patients had infratentorial lesions (group II). Only 10 patients (13.9%) in group I and three patients (15.0%) in group II showed laterality. Of these 13 patients, laterality occurred on the left side regardless of the side of the brain lesion. No relationships were found between swallowing laterality and location of stroke or motor weakness.Conclusion The results suggest that swallowing laterality was not prevalent among patients with stroke and that lesion side, location of the brain lesion, or motor weakness did not influence swallowing laterality. Although stroke can cause symptoms of dysphagia, it is difficult to conclude that stroke has a crucial impact on swallowing laterality. Objective To investigate whether patterns of dysphagia and swallowing laterality differ according to the location of brain lesions in patients with stroke.Methods Patients with stroke >20 years of age were enrolled in this study. A videofluoroscopic swallowing study (VFSS) including the anterior-posterior view was used to assess swallowing. Patterns of swallowing were classified into three types according to the width of barium sulfate flow while passing the pharyngoesophageal segment: right-side-dominant flow, left-side-dominant flow, and no laterality in flow. Laterality was defined when the width of one side was twice or more the width of the other side.Results A total of 92 patients who underwent swallowing function evaluations by VFSS were enrolled from Sep-tember 2012 to May 2013. Of these, 72 patients had supratentorial lesions (group I) and 20 patients had infratento-rial lesions (group II). Only 10 patients (13.9%) in group I and three patients (15.0%) in group II showed laterality. Of these 13 patients, laterality occurred on the left side regardless of the side of the brain lesion. No relationships were found between swallowing laterality and location of stroke or motor weakness.Conclusion The results suggest that swallowing laterality was not prevalent among patients with stroke and that lesion side, location of the brain lesion, or motor weakness did not influence swallowing laterality. Although stroke can cause symptoms of dysphagia, it is difficult to conclude that stroke has a crucial impact on swallowing laterality.

Clinical Differences of Diabetic Polyneuropathy or Carpal Tunnel Syndrome in Patients with Diabetes

양서연,김대열 대한근전도전기진단의학회 2015 대한근전도 전기진단의학회지 Vol.17 No.1

Objective: To investigate whether there are clinical differences in patients with diabetic peripheral polyneuropathy (DPN) or carpal tunnel syndrome (CTS). Method: 587 patients with diabetes mellitus who had an electrodiagnostic study to investigate whether they had DPN or CTS were enrolled. The patients were divided into DPN, CTS, DPN+CTS groups. General characteristics, diabetes-related factors, and associated complications were compared between these two groups. Results: Of the 587 diabetic patients, 111 patients had DPN, CTS or both. Among 111 patients, 47 had DPN (42.3%), 29 had CTS (26.1%) and 35 had both (31.5%). The results showed that the duration of diabetes was associated with DPN. Patients who had both DPN and CTS had higher levels of Hb1Ac, PP2, albumin/creatinine ratio, and longer duration of diabetes than the patients who had only DPN or CTS. Conclusion: These results suggest that patients with both DPN and CTS showed a higher level of Hb1Ac, PP2, a longer duration of diabetes or renal complications, more so than seen in patients who have only DPN or CTS. Therefore, nerve conduction studies are recommended for patients who have these risk factors to be screened out for both DPN and CTS.

한국어 말하기 능력 신장을 위한 플립드 러닝(flipped learning) 기반 문법 교육

양서연,오빛나래,이경,윤영 국제한국어교육학회 2017 국제한국어교육학회 춘계학술발표논문집 Vol.2017 No.-

An atypical case of Lemierre syndrome following oropharyngeal infection

양서연,정수진,박해열,이경화,천유진,김효은,김성한 고신대학교(의대) 고신대학교 의과대학 학술지 2018 고신대학교 의과대학 학술지 Vol.33 No.1

Lemierre syndrome is characterized by anaerobic bacterial infection in the head and neck and clinical or radiological evidence of internal jugular vein thrombophlebitis. The most common pathogens are Fusobacterium species, particularly F u s o b a c t e r i u m n e c r o p h o r u m . Septic emboli resulting from infected thrombophlebitis of the internal jugular vein leads to metastatic infections involving lung, liver, kidney, bone and central nervous system. The accurate diagnosis and treatment is important because it may be associated with a high mortality rate if untreated. We present a case of 28-year-old man with an atypical history for the diagnosis of Lemierre syndrome, which showed no definite evidence of internal jugular thrombophlebitis.

[이슈브리프] 차별하는 인공지능: AI가 확산할 수 있는 은연중 차별의 우려와 새로운 사회적 윤리의 필요성

양서연 한국여성정책연구원(구 한국여성개발원) 2019 젠더리뷰 Vol.54 No.-

F-114 Repeated Measurements of Fractional Exhaled Nitric Oxide (FeNO) Are Not Necessary for Screening of Asthma

양서연,김성한,변민광,김형중,안철민,김윤희,박혜정 대한결핵 및 호흡기학회 2017 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.124 No.-

Background: Although old guidelines recommend FeNO should be checked more than two times within the same session for asthma, recent studies showed excellent reproducibility of FeNO. This study aimed to determine whether repeated measurements of FeNO within the same session are necessary for asthma screening. Methods: We retrospectively reviewed electronic medical records of 132 adult outpatient subjects who visits pulmonary department of Gangnam Severance Hospital for asthma evaluation and tested FeNO measurement during June 2016 to July 2017. Results: Among total of 132 patients, 79 patients (59.8%) was diagnosed as asthma. Repeated FeNO measurements taken within the same session showed high reproducibility (Intraclass correlation coefficient > 0.9; P-value < 0.001) and strong correlation (Pearson’s coefficient > 0.9; P-value < 0.001); however, reliability and correlation was slightly weak in subjects with low FeNO (< 52.8 ppb). The value of repeated measurement was not significantly different in general; however, the value of FeNO measured at 2nd time was significantly higher than that measured at 1st time in subjects with lowest and highest lung function. The value of FeNO measured at 1st time was not inferior to that measured at 2nd time to predict asthma. After adjustment with lung function, the value of FeNO measured at 1st time (sensitivity, 80.5%; specificity, 85.1%) was superior to that measured at 2nd time (sensitivity, 76.6%; specificity 85.1%) to predict asthma.

이런 시베리아

양서연 메이데이 2022 Paper Vol.265 No.-

단절 및 거절도식과 결혼만족과의 관계에서 지각된 배우자지지의 매개효과: 자기효과 및 상대방효과 검증

양서연(Yang Seo Yeon),최한나(Choi Han Na) 숭실대학교 부부가족상담연구소 2020 가족과 상담 Vol.10 No.1

본 연구는 단절 및 거절도식과 결혼만족 간의 관계에서 지각된 배우자지지의 매개역할을 자기효과와 상대방효과로 검증하는 것이다. 이를 위해 결혼기간이 1년 이상인 부부 458명(229쌍)을 대상으로 단절 및 거절도식 척도, 지각된 배우자지지 척도, 개정판 부부적응 척도를 사용하였다. 자료분석은 자기-상대방 상호의존 모형(Actor-Partner Interdependent: APIM; Kenny, 1996)을 사용하였다. 연구결과는 다음과 같다. 첫째, 단절 및 거절도식이 결혼만족에 미치는 자기효과와 상대방효과 모두 유의하지 않는 것으로 나타났다. 둘째, 단절 및 거절도식이 지각된 배우자지지에 미치는 자기효과와 상대방효과는 모두 유의한 것으로 나타났다. 셋째, 지각된 배우자지지가 결혼만족에 미치는 자기효과와 상대방효과는 성별에 따라 차이를 보였다. 우선 남편과 아내의 자기효과는 모두 유의한 것으로 나타났다. 하지만 아내의 상대방효과는 유의하게 나온 반면, 남편의 상대방효과는 유의하지 않은 것으로 확인되었다. 넷째, 단절 및 거절도식과 결혼만족과의 관계에서 지각된 배우자지지의 매개효과 중 자기효과는 존재하는 것으로 확인되었다. 그러나 지각된 배우자지지의 상대방효과는 남편과 아내 간 성차가 있는 것으로 나타났다. 우선, 지각된 배우자지지는 아내의 단절 및 거절도식과 아내와 남편의 결혼만족 사이를 매개하는 것으로 확인되었다. 반면, 지각된 배우자지지는 남편의 단절 및 거절도식과 아내의 결혼만족을 매개하지 않는 것으로 나타났다. 이러한 연구결과를 바탕으로 부부상담 및 결혼상담에 대한 시사점과 추후연구를 위한 제언을 논의하였다. This study was conducted to examine the mediating effect of perceived marital support in the relationship between 229 couples married for more than a year participated in this study. The data was analyzed by using APIM(Actor-Partner Interdependent Model; Kenny, 1996). The results indicated disconnection and rejection schema has no relation to actor effect and partner effect in marriage satisfaction. Second, disconnection and rejection schema was related to both actor effect and partner effect in perceived marital support. Third, there was a significant difference between gender regards to both actor effect and partner effect when perceived marital support influences on marriage satisfaction. Both genders’ actor effect was related to marriage satisfaction through perceived marital support. However, while wives’ partner effect had an impact on marriage satisfaction through perceived marital support, husbands’ did not. The results indicated actor effect existed in the mediator effect of perceived marital support in the relationship of disconnection and rejection schema and marriage satisfaction. However, wives and husbands partner effect on perceived marital support were significantly different. The results indicated perceived marital support mediates the relationship between wives’ disconnection and rejection schema and both wives’ and husbands’ marriage satisfaction. On the other hand, perceived marital support did not mediate the relationship between husbands’ disconnection and rejection schema and wives’ marriage satisfaction. Implications for counseling practice and future studies were discussed.

NCBI 데이터베이스로부터 획득한 스트렙토마이신-저항 유전자, strA의 생태학적 진화에 대한 계통발생학적 추론

양서연 ( Seo-yeon Yang ),송형근 ( Hyung-geun Song ),조쉬알파나 ( Alpana Joshi ),이지훈 ( Ji-hoon Lee ) 한국환경농학회 2023 한국환경농학회 학술대회집 Vol.2023 No.0

Antimicrobial resistance has brought serious problems from widespread occurrences in agricultural soil, crops, and clinical facilities since both agricultural and clinical environments are closely related to human life. Because of the emergence and rapid expansion of antibiotic-resistant pathogenic bacteria, the antibiotic resistance issue has gained considerable attention. It has been known that most antibiotic resistances are acquired resistance, but there is also a high potential for lateral transfer of antibiotic resistance genes from other microorganisms, which are ecologically and taxonomically distinct. Some antibiotic resistance enzymes, aminoglycoside-inactivating enzymes possessed by various species of Streptomyces, were like R (antibiotic resistance) factors found in gram-negative bacteria of clinical isolation. Here, we have tried to suggest evolutionary inference for one of antibiotic resistance genes, strA, aminoglycoside phosphotransferase gene for streptomycin resistance, by phylogenetic analysis of strA genes retrieved from GenBank.