소아 골에 발생한 Ki-1 양성 T-세포 악성 림프종 -1예 보고 -

안혜선,한길로,손진희,서정일,고영혜 대한병리학회 1989 Journal of Pathology and Translational Medicine Vol.23 No.4

Elimination of Lancet-Related Needlestick Injuries Using a Safety-Engineered Lancet: Experience in a Hospital

안혜선,고수희,방지환,박상원 대한감염학회 2018 Infection and Chemotherapy Vol.50 No.4

Background: Lancet-related needlestick injuries (NSIs) occur steadily in clinical practices. Safety-engineered devices (SEDs) can systematically reduce NSIs. However, the use of SEDs is not active and no study to guide the implementation of SEDs was known in South Korea. The lancet-related NSIs may be eliminated to zero incidence using a SED lancet with effective sharp injury protection and reuse prevention features. Materials and Methods: We implemented a SED lancet by replacing a conventional prick lancet in a tertiary hospital in a sequential approach. A spot test of the new SED was conducted for 1 month to check the acceptability in practice and a questionnaire survey was obtained from the healthcare workers (HCWs). A pilot implementation of the SED lancet in 2 wards was made for 1 year. Based on these preliminary interventions, a hospital-wide full implementation of the SED lancet was launched. The incidence of NSIs and cost expenditure before and after the intervention were compared. Results: There were 29 cases of conventional prick lancet-related NSIs for 3 years before the full implementation of SED lancet. The proportion of prick lancet-related NSIs among yearly all kinds of NSIs during two years before the pilot study was average 11.7% (22/188). Pre-interventional baseline incidence of all kinds of NSIs was 7.01 per 100 HCW-years. After the full implementation of SED lancet, the lancet-related NSIs became zero in the 2nd year (P = 0.001). The average direct cost of 18,393 US dollars (USD) per year from device and post-exposure medical care before the intervention rose to 20,701 USD in the 2nd year of the intervention. The incremental cost-effectiveness ratio was 210 USD per injury avoided. Conclusion: The implementation of a SED lancet could eliminate the lancet-related NSIs to zero incidence. The cost increase incurred by the use of SED lancet was tolerable.

Steady Inflow of Vancomycin-Resistant Enterococci from Outside a Hospital

안혜선,박상원,고수희,방지환 대한의료관련감염관리학회 2017 의료관련감염관리 Vol.22 No.2

Background: Cross-transmission within hospitals has been considered a major source of vancomycin-resistant enterococci (VRE) acquisition. Inflow of VRE from outside hospitals may also be an important factor in South Korea.Methods: An active-point surveillance for VRE colonization was performed in one medical ward of a 767-bed hospital using single rectal swabs or stool samples. The proportion of VRE detected within 48 h of admission was sought. Risk factors for VRE acquisition were analyzed. To confirm the persistence of VRE inflow outside a single point, the degree of yearly VRE inflow was assessed by passive surveillance of clinical specimens over 2 years in the hospital, each one year before and after the active surveillance.Results: The active-point surveillance of 9 days resulted in 28 (28/72, 38.9%) VRE-positive patients, of whom nine (9/72, 12.5%) were patients were estimated to originate from outside the hospital. The duration of hospitalization and the use of antibiotics were significant risk factors for VRE colonization after admission, and the number of days from admission to first VRE positivity was a median of 8.5 (interquartile range, 2.7-15.0). During the 2 years, 213 patients were identified to be VRE-positive per clinical specimens with 95.5% of concurrent stool VRE, and 12.6% (27/213) were estimated to have acquired the infection from outside the hospital. This confirmed that the VRE inflow was continuous, but not transient or resembling an outbreak on one point.Conclusion: The inflow of VRE was steady in a tertiary hospital with an average infection control policy in South Korea and should be a further target for VRE control.

Effects of Newborn Care Education for First-time Fathers on Their Knowledge and Confidence in Newborn Care at Postpartum One Month

안혜선,방경숙 한국간호과학회 2014 Journal of Korean Academy of Nursing Vol.44 No.5

Purpose This study was conducted to identify the effects of newborn care education for fathers on their knowledge and confidence in newborn care at postpartum one month. Methods A nonequivalent control group pretest posttest design was used. The participants were 53 first-time fathers of newborns, 27 in experimental group, and 26 in control group. They were recruited at the nursery of one municipal hospital in Seoul. For the experimental group, a 50-minute education on newborn care using video, verbal education, demonstration and practice were provided prior to discharge. Fathers' knowledge and confidence in newborn care and their satisfaction with the education program were measured at postpartum one month. Results The fathers in the experimental group showed significantly higher knowledge (t=-4.51, p<.001), and confidence in newborn care (t=-2.29, p=.026) compared to the control group at postpartum one month. Fathers in the experimental group had a satisfaction score of 27.37±2.73 immediately after the education, and 25.30±3.40 at postpartum one month. Conclusion Results indicate that newborn care education for first-time fathers is an effective method in enhancing the level of knowledge and confidence in newborn care. It can be used in the nursery department before discharge as a useful nursing intervention.

식이지방의 종류와 Guar Gum의 첨가가 난소절제한 흰쥐의 지질대사에 미치는 영향

안혜선 한국영양학회 1997 Journal of Nutrition and Health Vol.30 No.10

This study examined the effect of dietary lipids and guar gum on lipid metabolism in ovariectomized rats. The experimental animals received ovarietomy (OVX). Lipids sources were divided into 3 groups (soybean oil(SB), beef tallow(BT)) and fish oil(FO)) and guar gum was supplemented to each lipid diet (SBG, BTG, FOG). Experimental diets were fed to therats for 16 weeks. Serum triglyceride (TG) levels were higher in the BT group and lower in the FO group as compared to the SB group .Serum total cholesterol (Tc) and HDL-C levels were lower in the FO group as compared to the SB group. Serum LDL-C and phospholipid levels were lower in the FO group as compared to the SB group. Serum lipids levels were lowered by guar gum supplement. Serum SFA(saturated fatty acids) contents were not significantly influenced by dietary lipids and guar gum. Serum MUFA(monounsaturated fatty acids) contents were the lowest in the SB group. Fecal weight was highest in the beef tallow group and lowest in the fish oil group. Fecal weight was increased by guar gum supplement in all lipid groups. Total bile acid content in feces was increased by guar gum supplement in the soybean oil and beef tallow groups. The endothelial cells of the beef tallow group changed from a flat shape to distorted round and enlarged shapes. The subendothelial layer was the thickness the thickest in the beef tallow group ; the interspace between elastic lamina was widened and elastic lamina was straightened and partly disrupted . The fish oil group showed more porminient endothelial cells and subendothelial layer. Internal elastic membrane and elastic lamina exhibited regularly wavy shapes. Guar gum supplement showed positive effects in all lipids groups. Based on the above results , it is suggested that beef tallow increased serum TG levels and injured the wall of the aorta. On the other hand, fish oil , which decreased serum lipid levels, has a positive effect on the walls of the aorta. Guar gum protects the aorta from injury by reducing the serum lipid levels. Therefore, it is suggested that soybean oil and beef tallow consumed with guar gum is beneficial.

주간 및 야간 여대생의 체형에 대한 인지와 체중조절 및 식습관에 대한 연구

안혜선,이상선 漢陽大學校 韓國生活科學硏究所 1999 韓國 生活 科學 硏究 Vol.- No.17

This study was performed to investigate the relationship between body image, weight control and eating habit. Among 134 female college students, a self-reported questionnaire was used, and the summary of the results are as follows 1) Average BMI of day-school female students were in the underweight category and average BMI of night-school female students were in the normal weight category. 2) Day-school female students were highly concerned for weight control and they attempted more weight control program than night-school female students. 3) In score of body image scale, day∼school female students were less satisfactory than night-school students. 4) Most of the female students wanted to be thinner than actual body image. 5) Night-school female students showed more regular eating habit and balanced diet than day-school female students. 6) In eating habit by score of body image scale, the group which have more satisfaction about body image had more regular eating habit and took mere balanced diet. However, the group which have less satisfaction about body image took less balanced diet. These results suggest that eating habit influenced by perception about body image. Therefore, female college students need nutrition education to have right perception and psychological satisfaction about image to maintain good health.

웨어러블 글래스 기반 스마트공장 장비-설비 예지보전 모니터링 시스템 구현

안혜선,송수호,이현,이남용 한국IT정책경영학회 2018 한국IT정책경영학회 논문지 Vol.10 No.5

In recent (the 4th industrial revolution era), various IT technologies and SW convergence technologies have been applied to the manufacturing industry in order to improve productivity. In general, the smart factory condition based monitoring service platform provides real-time monitoring technology using sensors and a system that supports decision making based on big data processing. In this study, we intend to implement smart factory condition based monitoring system, which provides product production as a service type. In particular, we provide AR/VR based monitoring service using wearable glass, so that we can diagnose and make prediction the status of the equipment on the basis of visualization. This is the part of the smart factory condition based monitoring service platform implementation. Finally, we tried to improve the accuracy of monitoring by developing data acquisition, real-time data processing, and data visualization program. They are implemented to realize the SW convergence technology that is needed in the actual manufacturing industry.

Endocrine-Mimicking Phytoestrogens: Heath Effects and Signaling

안혜선,계명찬 한국환경생물학회 2004 환경생물 : 환경생물학회지 Vol.22 No.4

Phytoestrogens display estrogen-like activity because of their structural similarity to human estrogens and exhibit high affinity binding for the estrogen receptors (ERs). The prevalence of phytoestrogens in our diets and the biological effects that they may cause need to be fully examined. ER is the ancestral receptor from which all other steroid receptors have evolved. Although phytoestrogens serve specific signaling functions between the plants and insects, fungi, and bacteria, many chemical signals are often misinterpreted as estrogenic signals in non- target organisms such as vertebrates. There are no ERs in plants or in their most common partners, insects. However, Rhizobium soil bacteria have NodD proteins which is an intended target of phytoestrogen signaling and share genetic homology with the ER. These two evolutionarily distant receptors both recognize and respond to a shared group of chemical signals and ligands, including both agonists and antagonists. This review briefly summarizes estrogen and estrogen receptors, kinds of important phytoestrogens, their health effects as well as some of the evolutionary aspects of mechanism by which phytoestrogen mimics the endogenous ER signaling in our body.

신세포암종의 병리학적 연구 -예후에 관련된 인자들 간의 상관관계 분석-

안혜선,박문향 대한병리학회 1992 Journal of Pathology and Translational Medicine Vol.26 No.6

읽기 문항 유형별 고등학생들의 영어 읽기전략 사용에 대한 연구

안혜선,배지영 한국영어학회 2022 영어학 Vol.22 No.-

The purpose of the present study is to analyze the patterns of Korean high school students’ use of reading strategies based on the question types for the College Scholastic Ability Test. This study analyzes learners of different reading proficiency levels using different reading strategies according to each of the five different question types. The participants of the study were two hundred eighty six students from third grade in a public girl’s high school located in Daejeon area. The questionnaire examined the correlation between the use of English reading strategies and reading proficiency using 24 questions. Strategies are selected from the Survey of Reading Strategies or SORS of Mokhatari and Sheorey (2002) and the questionnaires of Ikeda and Takeuchi (2000). Data collected from the experiment were statistically analyzed through SPSS(v.26). In order to verify the different use of reading strategies among the students in the three different English reading achievement levels, one-way ANOVA was used to analyze the statistical significance of each of the different groups. The findings are as follows. First, the upper, middle, and lower proficiency groups used different reading strategies for each question type, and the most frequently used reading strategies used by each group were statistically different by each question type. Second, the upper and middle proficiency groups are able to use the appropriate reading strategies depending on each question type. In conclusion, it suggests that understanding the pattern of the use of reading strategies based on the question type and English reading achievement level is not only important in teaching and learning reading but also in having students prepare for their reading test.