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안찬식,조암,An, Chan-Sik,Jo, Am 대한인간공학회 2004 大韓人間工學會誌 Vol.23 No.3
Today we are observing a lot of injuries, casualties, and property losses that are mainly caused by the defects of products. In order to derive safety designs, which minimize the possibility of such product liability-related accidents, we need to take into account the user-product interaction as an important part of the danger factor analysis. Existing risk analysis techniques, however, have some limitations in detecting comprehensive danger factors that are peculiarly involved in human errors and the functional defects of products. Researches on danger factor analysis regarding the user-product interaction have been carried out actively in ergonomics. In this paper, we suggest a novel product risk analysis technique, which is more objective and systematic compared to the previous ones, by combining a modified TAFEI (Task Analysis For Error Identification) technique with SASA (Systematic Approach to Accident Scenario Analysis) technique. By applying this technique to the product design practice in industry, corporations will be able to improve the product safety, consequently strengthening the competitiveness.
안찬식,Chang Hee Lee,변재호,이민희,정우경,Sang Hyun Choi,김도영,Young-Suk Lim,Young Seok Kim,김지훈,최문석,김명진 대한영상의학회 2019 Korean Journal of Radiology Vol.20 No.12
Objective: To compare the diagnostic accuracy of dynamic computed tomography (CT) and gadoxetate-enhanced magnetic resonance imaging (MRI) for characterization of hepatic lesions by using the Liver Imaging Reporting and Data System (LIRADS) in a multicenter, off-site evaluation. Materials and Methods: In this retrospective multicenter study, we evaluated 231 hepatic lesions (114 hepatocellular carcinomas [HCCs], 58 non-HCC malignancies, and 59 benign lesions) confirmed histologically in 217 patients with chronic liver disease who underwent both gadoxetate-enhanced MRI and dynamic CT at one of five tertiary hospitals. Four radiologists at different institutes independently reviewed all MR images first and the CT images 4 weeks later. They evaluated the major and ancillary imaging features and categorized each hepatic lesion according to the LI-RADS v2014. Diagnostic performance was calculated and compared using generalized estimating equations. Results: MRI showed higher sensitivity and accuracy than CT for diagnosing hepatic malignancies; the pooled sensitivities, specificities, and accuracies for categorizing LR-5/5V/M were 59.0% vs. 72.4% (CT vs. MRI; p < 0.001), 83.5% vs. 83.9% (p = 0.906), and 65.3% vs. 75.3% (p < 0.001), respectively. CT and MRI showed comparable capabilities for differentiating between HCC and other malignancies, with pooled accuracies of 79.9% and 82.4% for categorizing LR-M, respectively (p = 0.139). Conclusion: Gadoxetate-enhanced MRI showed superior accuracy for categorizing LR-5/5V/M in hepatic malignancies in comparison with dynamic CT. Both modalities had comparable accuracies for distinguishing other malignancies from HCC.
안찬식,이영한,김성준,조희우,서진석,송호택 대한자기공명의과학회 2013 Investigative Magnetic Resonance Imaging Vol.17 No.1
Purpose : The purpose of this study was to find and categorize the various magnetic resonance imaging (MRI) findings of spinal metastases that correlate with the type of primary cancer. Materials and Methods: We retrospectively reviewed gadolinium-enhanced magnetic resonance images of 30 patients with 169 spinal metastatic lesions from lung cancer (n = 56), breast cancer (n = 29), colorectal cancer (n = 20), hepatocellular carcinoma (HCC) (n = 17), and stomach cancer (n = 47). The size, location, extent of invasion, signal intensity, margin,enhancement pattern, and osteoblastic or osteolytic characteristics of each metastatic tumor were analyzed. Results: The metastatic lesions from HCC were larger than those from the other primary tumors (P < 0.05) except for colorectal cancer (P = 0.268). Well-defined metastatic tumor margins were more frequently seen in lung cancer and breast cancer (P < 0.01). All but HCC showed a tendency to invade the vertebral body rather than the posterior elements (P <0.02). Colorectal cancer and HCC showed a tendency toward extraosseous invasion without statistical significance. HCC showed a characteristic enhancement pattern of ‘worms-in-a-bag’. Rim enhancement with a sclerotic center was only seen in spinal metastases from stomach cancer. Conclusion: Despite many overlapping imaging features, spinal metastases of various primary tumors display some characteristic MRI findings that can help identify the primary cancer.