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        • 부산지역 제조업 근로자들의 요통과 작업환경과의 관계

          안소윤,신해림,손성근,김용완 인제대학교 1991 仁濟醫學 Vol.12 No.1

          산업장 근로자들의 요통과 작업환경과의 관계를 조사한 결과 근로자들의 요통경험율은 58.4%였으며 현재 직업과 관련된 요통경험율은 요통근로자들의 54.1%였다. The low back pain (LBP) is not a new problem and it has been a major problem in industry. This study has been made to determine self-reported LBP rate and to know the relation between work environment and work-related LBP by questionnaire survey. The study subjects are 269 workers in the manufacturing industries in Pusan and the study period is from December 1 to 30 in 1989. The results are summerized as follows; 1.The mean age of the workers are 35.11±10.3 years and 64.4% of workers are 20-40 years. 2.Self-reported LBP rate is 58.4% among the 269 workers. 3.54.l% of LBP workers complaint work-related back pain(WBP). 4.There were significant differences between LBP workers and WBP workers about the fitness of the working chair (p<0.01), the fitness of the working table (p<0.05).

        • KCI등재SCIESCOPUS

          Permissive Hypotension in Extremely Low Birth Weight Infants (≤1000 gm)

          안소윤,박원순,김은선,김진규,신정희,성세인,정지미,장윤실 연세대학교의과대학 2012 Yonsei medical journal Vol.53 No.4

          Purpose: We performed this study to evaluate the safety of permissive hypotension management in extremely low birth weight infants (ELBWIs). Materials and Methods: Medical records of all inborn ELBWIs admitted to Samsung Medical Center from January 2004 to December 2008 were reviewed retrospectively. Of a total of 261 ELBWIs, 47 (18%) required treatment for hypotension (group T), 110(42%) remained normotensive (group N), and 104 (40%) experienced more than one episode of hypotension without treatment (group P) during the first 72 hours of life. Treatment of hypotension included inotropic support and/or fluid loading. Results: Birth weight and Apgar scores were significantly lower in the T group than the other two groups. In the N group, the rate of pathologically confirmed maternal chorioamnionitis was significantly higher than other two groups, and the rate was higher in the P group than the T group. After adjusting for covariate factors,no significant differences in mortality and major morbidities were found between the N and P groups. However, the mortality rate and the incidence of intraventricular hemorrhage (≥stage 3) and bronchopulmonary dysplasia (≥moderate)were significantly higher in the T group than the other two groups. Long term neurodevelopmental outcomes were not significantly different between the N and P groups. Conclusion: Close observation of hypotensive ELBWIs who showed good clinical perfusion signs without intervention allowed to avoid unnecessary medications and resulted in good neurological outcomes.

        • KCI등재

          The effect of rooming-in care on the emotional stability of newborn infants

          안소윤,고선영,김경아,이연경,신손문 대한소아청소년과학회 2008 Clinical and Experimental Pediatrics (CEP) Vol.51 No.12

          Purpose : We aimed to examine the effect of rooming-in care on newborn infants emotional stability by comparing them with those cared for in a nursery. Methods : Forty-eight full-term newborn infants born at Cheil General Hospital between July 1 and October 31, 2007, were enrolled. Twenty-four newborn infants were roomed-in in their mothers rooms (rooming-in group), and 24 newborns were cared for in the hospital nursery (the nursery group) for the first 3 days of their lives. Those with perinatal problems that required medical treatment were excluded. By using Brazeltons neonatal behavior assessment scale, we measured irritability and self-quieting as well as the duration of crying after heel-stick puncture for the newborn metabolic screening test. Results : The rooming-in group had a higher irritability score than the nursery group (6.8±1.7 vs. 4.2±2.1, P<0.001), thereby suggesting stable behavior against external irritation; the former also had a higher self-quieting activity score (5.9±0.3 vs. 4.5±1.8, P=0.001), thereby suggesting that stability was reached quickly from the irritated state. Time taken to stop crying after the heel-stick puncture was significantly shorter in the rooming-in group than in the nursery group (17±15.1 seconds vs. 115.3±98.5 seconds, P<0.001). Conclusion : These results show that newborn infants in the rooming-in group exhibit more stable behavior against external irritation and can be stabilized from an irritated state more quickly than infants cared for in the nursery, even after a few days of rooming-in care. Purpose : We aimed to examine the effect of rooming-in care on newborn infants emotional stability by comparing them with those cared for in a nursery. Methods : Forty-eight full-term newborn infants born at Cheil General Hospital between July 1 and October 31, 2007, were enrolled. Twenty-four newborn infants were roomed-in in their mothers rooms (rooming-in group), and 24 newborns were cared for in the hospital nursery (the nursery group) for the first 3 days of their lives. Those with perinatal problems that required medical treatment were excluded. By using Brazeltons neonatal behavior assessment scale, we measured irritability and self-quieting as well as the duration of crying after heel-stick puncture for the newborn metabolic screening test. Results : The rooming-in group had a higher irritability score than the nursery group (6.8±1.7 vs. 4.2±2.1, P<0.001), thereby suggesting stable behavior against external irritation; the former also had a higher self-quieting activity score (5.9±0.3 vs. 4.5±1.8, P=0.001), thereby suggesting that stability was reached quickly from the irritated state. Time taken to stop crying after the heel-stick puncture was significantly shorter in the rooming-in group than in the nursery group (17±15.1 seconds vs. 115.3±98.5 seconds, P<0.001). Conclusion : These results show that newborn infants in the rooming-in group exhibit more stable behavior against external irritation and can be stabilized from an irritated state more quickly than infants cared for in the nursery, even after a few days of rooming-in care.

        • 과긴장과 저긴장의 기전과 치료 : NDT approach 를 중심으로

          안소윤 대한물리치료학회 1995 대한물리치료학회지 Vol.7 No.1

          Therapist have many troubles in the treatment of the patients who have a disorder in Centural Nerve System. It is the role of therapist that is to discriminate and control tone in the patients. In the case of hypertonus to be with hypotonus it is needed for therapist to inhibite the tonus properly without being influenced from the associated reaction. In this study the therapeutic control of the hypertonus and hypotonus through the Bobath approach is presented in detail. It is suggested that the Holistic approach using the plasticity of patients base on the Bobath concept is to be used in the improvement of activities and functions of individual patients.

        • KCI등재후보

          물리치료사와 물리치료과 학생의 성별에 따른 HIV/AIDS에 대한 지식과 태도

          안소윤,김종순 대한정형도수치료학회 2005 대한정형도수물리치료학회지 Vol.11 No.2

          The purpose of this descriptive study is to investigate the general knowledge and attitude about HIV/AIDS among gender in physical therapists and physical therapy students. AIDS a clinical syndrome that involves progressive immune deficiency and consequent development of opportunistic infection, tumors, neurologic disease and systemic wasting with chronic trends. Many medical specialists are afraid of AIDS patients because they have a little information of AIDS and fear of HIV infection from AIDS patients at work site. This study surveyed 649 physical therapists and physical therapy students by means of a self-administered questionnaire. This study was carried out from April, 2003 to October, 2003 for collecting data. The findings of this study can be summarized as follows. 1) The male and female physical therapist and physical therapy students who have an experience of educational program for HIV/AIDS show higher general knowledge about HIV/AIDS. 2) The male physical therapist and physical therapy students were conscious of the need for physical therapeutic intervention for the complication of HIV/AIDS. 3) The male who has higher general knowledge about HIV/AIDS are conscious of the need for educational program about HIV/AIDS. 4) The male and female want to have the choice to accept or reject the HIV/AIDS patients for treatment. 5) The knowledge of transmission mode in sexual intercourse of HIV/AIDS influence the attitude of male and female to patients with HIV/AIDS. 6) The knowledge of prevention of HIV/AIDS influence the attitude of male and female to patients with HIV/AIDS. 7) The knowledge of regarding symptom of HIV/AIDS influence the attitude of female to patients with HIV/AIDS. 8) The knowledge of general transmission mode of HIV/AIDS influence the attitude of male and female to patients with HIV/AIDS. 9) The knowledge of transmission risk factors in work site of HIV/AIDS influence the attitude of male and female to patients with HIV/AIDS. 10) The knowledge of needs for prevention in work site of HIV/AIDS influence the attitude of male and female to patients with HIV/AIDS. In conclusion, male and female with more knowledge of HIV/AIDS could positively treat HIV/AIDS patients.

        • KCI등재

          Mesenchymal stem cells transplantation for neuroprotection in preterm infants with severe intraventricular hemorrhage

          안소윤,장윤실,박원순 대한소아청소년과학회 2014 Clinical and Experimental Pediatrics (CEP) Vol.57 No.6

          Severe intraventricular hemorrhaging (IVH) in premature infants and subsequent posthemorrhagichydrocephalus (PHH) causes significant mortality and life-long neurological complications, includingseizures, cerebral palsy, and developmental retardation. However, there are currently no effectivetherapies for neonatal IVH. The pathogenesis of PHH has been mainly explained by inflammationwithin the subarachnoid spaces due to the hemolysis of extravasated blood after IVH. Obliterativearachnoiditis, induced by inflammatory responses, impairs cerebrospinal fluid (CSF) resorption andsubsequently leads to the development of PHH with ensuing brain damage. Increasing evidence hasdemonstrated potent immunomodulating abilities of mesenchymal stem cells (MSCs) in various braininjury models. Recent reports of MSC transplantation in an IVH model of newborn rats demonstratedthat intraventricular transplantation of MSCs downregulated the inflammatory cytokines in CSF andattenuated progressive PHH. In addition, MSC transplantation mitigated the brain damages that ensueafter IVH and PHH, including reactive gliosis, cell death, delayed myelination, and impaired behavioralfunctions. These findings suggest that MSCs are promising therapeutic agents for neuroprotection inpreterm infants with severe IVH.

        • KCI등재SCIESCOPUS

          Stem Cell Therapy for Bronchopulmonary Dysplasia: Bench to Bedside Translation

          안소윤,장윤실,박원순 대한의학회 2015 Journal of Korean medical science Vol.30 No.5

          Bronchopulmonary dysplasia (BPD), a chronic lung disease affecting very premature infants, is a major cause of mortality and long-term morbidities despite of current progress in neonatal intensive care medicine. Though there has not been any effective treatment or preventive strategy for BPD, recent stem cell research seems to support the assumption that stem cell therapy could be a promising and novel therapeutic modality for attenuating BPD severity. This review summarizes the recent advances in stem cell research for treating BPD. In particular, we focused on the preclinical data about stem cell transplantation to improve the lung injury using animal models of neonatal BPD. These translational research provided the data related with the safety issue, optimal type of stem cells, optimal timing, route, and dose of cell transplantation, and potency marker of cells as a therapeutic agent. Those are essential subjects for the approval and clinical translation. In addition, the successful phase I clinical trial results of stem cell therapies for BPD are also discussed.

        • KCI등재SCIESCOPUS

          Quantitative in Vivo Detection of Brain Cell Death after Hypoxia Ischemia Using the Lipid Peak at 1.3 ppm of Proton Magnetic Resonance Spectroscopy in Neonatal Rats

          안소윤,박원순,유혜수,이장훈,성동경,정유진,성세인,임근호,장윤실,이정희,김기수 대한의학회 2013 Journal of Korean medical science Vol.28 No.7

          This study was performed to determine the accuracy of proton magnetic spectroscopy (1H-MRS) lipid peak as a noninvasive tool for quantitative in vivo detection of brain cell death. Seven day-old Sprague Dawley rats were subjected to 8% oxygen following a unilateral carotid artery ligation. For treatment, cycloheximide was given immediately after hypoxic ischemia (HI). Lipid peak was measured using 1H-MRS at 24 hr after HI, and then brains were harvested for fluorocytometric analyses with annexin V/propidium iodide (PI) and fluorescent probe JC-1, and for adenosine-5'-triphosphate (ATP) and lactate. Increased lipid peak at 1.3 ppm measured with 1H-MRS, apoptotic and necrotic cells, and loss of mitochondrial membrane potential (ΔΨ) at 24 hr after HI were significantly improved with cycloheximide treatment. Significantly reduced brain ATP and increased lactate levels observed at 24 hr after HI showed a tendency to improve without statistical significance with cycloheximide treatment. Lipid peak at 1.3 ppm showed significant positive correlation with both apoptotic and necrotic cells and loss of ΔΨ, and negative correlation with normal live cells. Lipid peak at 1.3 ppm measured by 1H-MRS might be a sensitive and reliable diagnostic tool for quantitative in vivo detection of brain cell death after HI.

        • KCI등재

          Pseudohypoaldosteronism in a premature neonate with severe polyhydramnios in utero

          안소윤,신손문,김경아,이연경,고선영 대한소아청소년과학회 2009 Clinical and Experimental Pediatrics (CEP) Vol.52 No.3

          We report a case of a premature newborn baby who presented with hyponatremia, hyperkalemia, and metabolic acidosis accompanied by severe polyhydramnios in utero. The baby was diagnosed with pseudohypoaldosteronism on the basis of normal 17-hydroxyprogesterone levels, elevated aldosterone, and clinical symptoms. His serum electrolyte levels were corrected with sodium chloride supplementation. Sodium supplementation was reduced gradually and discontinued at 5 months of age. At 5 months, the child was able to maintain normal serum electrolyte levels without oral sodium chloride supplementation, and showed normal physical and neurological development. This case illustrates that pseudohypoaldosteronism must be considered if a newborn infant with an antenatal history of severe polyhydramnios shows excessive salt loss with normal levels of 17-hydroxyprogesterone.

        • KCI등재후보

          물리치료(학)과 졸업생의 취업준비 노력과 성과

          안소윤,안성자,권해연,Ahn,,So,Youn,An,,SeongJa,Kwon,,HaeYeon 대한물리치료과학회 2014 대한물리치료과학회지 Vol.21 No.1

          Background : This study aims to examine actual conditions of college students' life, behaviors to prepare for employment, and employment performance, thereby providing basic materials to create efficient measures for college students' employment strategies. Method : The subjects of this study were 207 graduates from the Department of Physical Therapy employed in medical and health institutions in Gyeongsangnam-do and Busan. Aquestionnaire devised by Yu Yeon-wha and Lim Gyeong-ae(2012, 2011) was revised and complemented into a self-reporting questionnaire composed of 29 questions. The collected data was analyzed using SPSS Win 18.00 program. Results : 1) The biggest reason for the respondents' selecting physical therapy as a major was bright prospect for employment, and the largest percent of the respondents answered that they started to prepare for employment in the second semester of junior year. 2)Regarding behaviors to prepare for employment, those who largely provided information on employment were the respondents' seniors and friends. 62.3% of the respondents owned certificates and diplomas. 59.9% took part in programs related to employment in order to prepare for employment. Their weakest area was English and what they wanted to know most was annual salaries provided by companies. They put self-development and growth potential before everything as what should be considered in priority when getting a job. 3)The most frequently asked question in their interviews for employment was the motive for application. The biggest reason for their employment at their current institution was their good personality and manner. 4)As for employment performance, they were unsatisfied with their current average annual salary. Conclusion : School should provide consciousness education and employment coaching so that students can early prepare for employment with an active attitude. In particular, educational environment where many students can gain easy access to information about employment in diverse areas should be provided and student coaching should be actively conducted.

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