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      • 폐경후 여성에서 치료 약제에 따른 부위별 골밀도의 변화

        안봉수,신재규,주원찬,송민호,노흥규 충남대학교 의과대학 지역사회의학연구소 1996 충남의대잡지 Vol.23 No.2

        Because of the prolongation of life span, the postmenopausal osteoporosis is a serious health problem, which needs active preventive and conservative measures. Recent evidence suggests that estrogen replacement therapy .(ERT), calcitonin, bisphosphonate and ipriflavone treatments are effective in preventing bone loss in postmenopausal women. In this study, we evaluated the effects of estrogen, ipriflavone, and combined therapy with estrogen and ipriflavone to BMD in various bone sites (lumbar spine, femoral neck and Ward's triangle). Forty-eight patients were devided into 3 groups by treatment modalities which are estrogen and ipriflavone group (n=12). After basal bone mineral desity (BMD) were determined by DEXA. (Dual energy X-ray absorptiometry. Lunar Radiation Corp. U. S. A. ), the patient were received medication according to each treatment protocol. The patients with estrogen treatment group were 2mg estradiol and 10mg of medroxy progesterone for 21 days a month. The patients of ipriflavone treatment group were received 600mg daily. The patients with combined therapy with estrogen and ipriflavone were received same dose of other two treatment groups. The BMD after treatment were compaired with basal BMD. The results were as follows. 1) The BMD in lumbar spine and femoral neck were significantly increased after estrogen treatment. 2) The BMD in lumar spine was significantly increased after ipriflavone treatment but the BMD in femoral neck and Ward's triangle were not increased with ipriflavone treatment. 3) After combined therapy with estrogen and ipriflavone, the BMD in each sites were increased and the BMD in Ward's triangle was more incresed than estrogen or ipriflavone treatment alone. In conclusion, estrogen prevented cortical bone and trabecular bone loss. ipriflavone prevented trabecular bone loss. The combination with estrogen and ipriflavone was increased effects of estrogen to prevent trabecular bone loss.

      • KCI등재

        수소환원법으로 제조된 나노구조 Fe-Co 합금분말의 미세구조 및 자성특성

        안봉수,이백희,이규환,김영도,An, Bong-Su,Lee, Baek-Hui,Lee, Gyu-Hwan,Kim, Yeong-Do 한국재료학회 2002 한국재료학회지 Vol.12 No.6

        Magnetic properties of nanostructured materials are affected in complicated manner by their microstructure such as grain size, internal strain and crystal structure. Thus, studies on the synthesis of nanostructured materials with controlled microstructure are necessary for a significant improvement in magnetic properties. It is well known that when Fe-Co alloy undergoes ordering transformation, soft magnetic properties could be obtained. There are many reports that the magnetic properties of the materials can be changed with variation of grain size. In the present work, nanostructured Fe-50at.%Co alloy powder produced by hydrogen reduction process (HRP) starting with two oxide powder mixtures of $Fe_2O_3\;and\; Co_3O_4$. The mean grain size of the HRP powders was about 40 nm and coercivity of the: powders was about 43 Oe.

      • KCI등재

        제주 4·3사건 이후 공동체 안전과 회복력에 관한 연구 -불신과 갈등에서 상생과 발전으로-

        안봉수,김철수 한국경찰연구학회 2023 한국경찰연구 Vol.22 No.2

        The safety of the community was examined mainly by the fear, conflict, mistrust, and frustration that spread in the community after the 4·3 incident. The 4·3 incident that residents remember was the first painful memory of the "Massacre" before the political or social movement character. In particular, the residents who suffered from the 4·3 incident themselves remembered that 100% of it was the "Massacre." As such, even after the end of the 4·3 incident, the memories of 4·3 were filled with "pain" and "fear." Moreover, 80% of the direct victims of the 4·3 incident in particular said "violence and suffering." After the 4·3 incident, complex relationships such as grudges were formed between village community members, and conflicts also emerged between the villagers. After the 4·3 incident, faith in the police, administrative authorities, or public institutions, plummeted, and the distrust of the affected residents who experienced the 4·3 incident was very high. These conditions weakened the sense of community belonging and hindered its development. However, the community had the task of rebuilding and developing again after the collapse after the closure of the incident. Before securing the material resources of the community, the will of the villagers to work together to achieve the development of the village and the belief that such efforts would bring good results. The will and faith of the villages surveyed were high. Regardless of gender, age, or type of damage, the villagers had a strong will to resolve and overcome the inherent conflicts after the 4·3 incident and the will to solve problems. As a result of the joint efforts of the villagers and the bereaved families who experienced the 4·3 incident to achieve the development of the village beyond 4·3, the community has recovered from its wounds and made remarkable progress in the local area more than 20 years later. The 4·3 incident was an unfortunate historical event that had a great impact on the disappearance and disintegration of the community. The peaceful community was reduced to a region of antagonism and conflict for seven years and seven months. The second half of the 20th century, a time of destruction and restoration of village communities, was dominated by the principle of individual and community security. Perhaps the experiences and memories of the 4·3 incident also acted as a fundamental factor in community development, strengthening the cohesion within the community, influencing the prevention of recurrence and the formation of volitional attitudes for village development. 4·3사건은 마을공동체의 소멸, 붕괴에 큰 영향을 미친 불행한 역사적 사건이었다. 조사연구 결과, 주민들이 기억하는 4·3사건은 정치적 또는 사회운동론적 성격 규정 이전에 ‘양민학살’이라는 기억이 제일 먼저 떠오르고 있었다. 특히 4·3사건을 직접 겪으면서 피해를 입은 주민들은 100%가 ‘양민학살’이었다고 기억하는 상태였다. 그런 만큼 4·3사건이 종료된 이후에도 4,3에 대한 기억은 ‘고통’과 ‘공포’로 점철되어 있었다. 4·3사건 이후 공동체 구성원들간에는 원한관계 등 복잡한 관계들이 형성되면서 주민들간에 갈등도 나타났다. 경찰과 행정관청 곧 공공기관에 대한 믿음은 추락했고 4·3사건을 직접 겪은 피해 주민들의 불신은 매우 높았다. 이러한 상태들은 공동체 소속감을 약화시켰고 공동체의 발전을 저해하였다. 그러나 마을공동체는 사건 종결 후 붕괴를 딛고 다시 재건과 발전을 동시에 이루어야 하는 과제를 안고 있었다. 공동체의 물질적 자원을 확보하기 전에 주민들이 서로 합심하여 마을 발전을 이루려는 의지와 구성원들간의 믿음이 먼저 요구되었다. 4·3사건 이후 마을사람들 사이에 내재한 갈등을 해결하고 극복하려는 의지와 문제해결 의지가 강했고, 20여년 후부터 지역내에서 상처를 회복하고 발전을 이루었다. 4·3 이후 공동체의 안전확보와 회복노력은 4·3사건의 참혹함에 저항하기 위한 공동체적 연대의 결과이며, 4·3사건의 경험과 기억들은 공동체 내부의 응집력을 강화했고, 마을발전의 의지적 태도 형성에 영향을 주면서 공동체 발전의 원천적 요인으로 작용했다.

      • 인슐린 비의존형 당뇨병에 합병된 관상동맥질환의 임상소견과 관상동맥 조영 소견에 대한 고찰

        구본정,안봉수,정진옥,성인환,전은석,송민호,노흥규,김영건 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1

        Diabetes mellitus has a major impact on cardiac morbidity and mortality. We analyzed the clinical characteristics and coronary angiographic finding in patients with a coronary artery disease and with noninsulin dependent diabetes mellitus We retrospectively reviewed the clinical and coronary angiographic findings in 74 patients with noninsulin dependent diabetes millitus and in 328 non-diabetic patients who a coronary insufficiency. Significant coronary occlusions and multiple coronary artery diseases were more common in diabetics than in non-diabetics. The patients with noninsulin dependent diabetes mellitus has several limiting factors to perform the successful percutaneous coronary angioplasty, it could bo a possible factor of rapid deterioration of coronary insufficiency in patients with diabetes mellitus. Smoking, hypertension significantly increased the incidence of significant coronary occlusions whereas obesity and hypercholesterolemia did not any significant influence on incidence of the significant coronary occlusions. The longer duration of diabetes mellitus associated with higher incidence of significant coronary occlusions and multiple coronary diseases. Significant coronary occlusions and multiple coronary artery diseases were occurred more common in diabetics than in non-diabetics. However, the patients with noninsulin dependent diabetes mellitus has several limiting factors to perform the successful percutaneous coronary angiolasty. Hypertension and smoking significantly increased the incidence of significant coronary occlusions.

      • 골밀도 측정의 부위별 차이에 따른 임상적 의의

        노흥규,안봉수,신재규 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2

        Osteoporosis is a common clinical problem with high risk of fracture in old age, especially postmenopausal women. Secondary causes of osteoporosis can be identified in 20% of women and 40% of men with vetebral fracture. One of the cause of secondary osteoporosis is endocrine disease such as hypogonadism, ovarian agenesis, hyperthyroidism, hyperadrenocorticism, hyperparathyroidism and diabetes mellitus. The degree of bone loss in cortical and trabecular bone is different according to the cause of osteoporosis and the measurement of bone mineral densities on various sites is important to assure the feature of bone loss in various types of osteoporosis. To determine changes in the bone mineral density in women with postmenopause and with hyperthyroidism, we measured the bone mineral density (BMD) of lumbar spine and femoral neck by dual energy X-ray absorptiometry (DEXA) in 47 patients with postmenopause and 24 patients with hyperthyroidism. The result were as follows : 1) The BMD of lumbar spine and femoral neck in postmenopausal osteoporosis and hyperthyroidism patients are significantly lower than normal controls. 2) No significant difference in the patient/normal ratios of spine and femoral neck in both diseases.

      • KCI등재

        나노 구조 Fe-Co 합금분말의 제조 및 자성특성

        이백희,안봉수,김대건,김영도 한국분말야금학회 2002 한국분말재료학회지 (KPMI) Vol.9 No.3

        Conventional Fe-Co alloys are important soft magnetic materials that have been widely used in industry. Compared to its polycrystalline counterpart, the nanostructured materials have showed superior magnetic properties, such as higher permeability and lower coercivity due to the single domain configuration. However, magnetic properties of nanostructured materials are affected in complicated manner by their microstructure such as grain size, internal strain and crystal structure. Thus, studies on synthesis of nanostructured materials with controlled microstructure are necessary for a significant improvement in magnetic properties. In the present work, starting with two powder mixtures of Fe and Co produced by mechanical alloying (MA) and hydrogen reduction process (HRP), differences in the preparation process and in the resulting microstructural characteristics will be described for the nano-sized Fe-Co alloy particles. Moreover, we discuss the effect of the microstructure such as crystal structure and grain size of Fe-Co alloys on the magnetic properties.

      • 담석증 환자에서의 ^(99m)Tc-DISIDA 간담도스캔의 소견 분석

        미애,안봉수,신재규,김진환,이헌영,노흥규 충남대학교 의과대학 지역사회의학연구소 1996 충남의대잡지 Vol.23 No.1

        ^99mTc-DISIDA scan findings in 90 patients with gall bladder stone (GB stone) were analyzed according to the complications of GB stone retrospectively. The results are as follows: 1. Among the 90 patients with GB stone, 48 cases had simple GB stone, 25 cases were complicated with acute cholecystitis, 8 cases with chronic cholecystitis and 9 cases with IHD and CBD stones. 2. The findings of ^99mTc-DISIDA scan were normal in 41 patients(46% ), nonvisualized GB in 39 patients(43%) and delayed intestinal excretion in 15 patients(17 % ). 3. Among the 15 cases with nonvisualized GB with other findings, 7 cases had delayed intestinal excretion, 5 cases had no intestinal excretion and 3 cases had decresed hepatic excretion. The above results mean that the ^99mTc-DISIDA scan with GB stone shows various findings according to the complications of stone.

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