새로운 상호연결망 하프 버블정렬 그래프 설계 및 성질 분석

서정현,심현,이형옥,Seo, Jung-Hyun,Sim, Hyun,Lee, Hyeong Ok 한국정보통신학회 2017 한국정보통신학회논문지 Vol.21 No.7

버블정렬 그래프는 노드 대칭이며 데이터 정렬 알고리즘에 활용 할 수 있다. 본 연구에서는 버블정렬 그래프의 망 비용을 개선한 하프 버블정렬 그래프를 제안하고 분석한다. 하프 버블정렬 그래프 $HB_n$의 노드수는 n!이고 분지수는 ${\lfloor}n/2{\rfloor}+1$이다. 하프 버블정렬 그래프의 분지수는 버블정렬 그래프의 분지수의 $${\sim_=}0.5$$배 이고, 지름은 $${\sim_=}0.9$$배 이다. 버블정렬 그래프의 망 비용은 $${\sim_=}0.5n^3$$이고, 하프 버블정렬 그래프의 망 비용은 $${\sim_=}0.2n^3$$이다. 하프 버블정렬 그래프는 버블정렬 그래프의 서브 그래프임을 증명하였다. 추가로 라우팅 알고리즘을 제안하였고 지름을 분석하였다. 마지막으로 버블정렬 그래프와 망 비용을 비교 하였다. The Bubble sort graph is node symmetric, and can be used in the data sorting algorithm. In this research we propose and analyze that Half Bubble sort graph that improved the network cost of Bubble sort graph. The Half Bubble sort graph's number of node is n!, and its degree is ${\lfloor}n/2{\rfloor}+1$. The Half Bubble sort graph's degree is $${\sim_=}0.5$$ times of the Bubble sort, and diameter is $${\sim_=}0.9$$ times of the Bubble sort. The network cost of the Bubble sort graph is $${\sim_=}0.5n^3$$, and the network cost of the half Bubble sort graph is $${\sim_=}0.2n^3$$. We have proved that half bubble sort graph is a sub graph of the bubble sort graph. In addition, we proposed a routing algorithm and analyzed the diameter. Finally, network cost is compared with the bubble sort graph.

『新纂辟瘟方』의 編制와 內容에 대한 考察

심현아(Hyun-A Sim),송지청(Ji-Chung Song),금경수(Kyung-Su Keum),엄동명(Dong-Myung Eom) 한국의사학회 2013 한국의사학회지 Vol.26 No.2

Objective : 『Shinchanbyeokonbang』(printed in 1613) was written by Heo Joon, who is an author of 『Dongeuibogam』(also printed in 1613). Even though 『Dongeuibogam』 has 「Onyeok」(chapter for pestilence), Heo Joon wrote technical book for pestilence as name as 『Shinchanbyeokonbang』. Therefore, we try to compare 『Shinchanbyeokonbang』 with 『Dongeuibogam』「Onyeok」. Method : We compared formation and contents of 『Shinchanbyeokonbang』 with 『Dongeuibogam』「Onyeok」. Result : 『Shinchanbyeokonbang』 has entirely new contents than 『Dongeuibogam』「Onyeok」 in somehow, almost contents of 『Dongeuibogam』 「Onyeok」 are in 『Shinchanbyeokonbang』 though. Also 『Shinchanbyeokonbang』 reorganized prescrptions for pestilence not only in 『Dongeuibogam』 「Onyeok」 but also in 『Dongeuibogam』 ; 「Han」, 「Hwangdal」, 「Hwa」, 「Yinhoo」, 「Hyeol」, 「Seup」 and 「Sasoo」. Conclusion : 『Shinchanbyeokonbang』 was printed by Heo Joon at the same time when 『Dongeuibogam』 was printed in 1613. However, 『Shinchanbyeokonbang』 has newly formation and contents is some aspects comparing to 『Dongeuibogam』「Onyeok」, which is the similar chapter for pestilence because this book is the technical book for pestilence.

학교 밖 청소년의 진로장애가 진로탐색행동에 미치는 영향 : 자아존중감, 우울의 매개효과

심현아(Sim Hyun A) 학습자중심교과교육학회 2020 학습자중심교과교육연구 Vol.20 No.1

본 연구는 학교 밖 청소년이 지각한 진로장애와 진로탐색행동의 관계에서 자아존중감과 우울의 매개효과를 살펴보는 데 주된 목적이 있다. 본 연구에서는 한국청소년정책연구원에서 수행한 「학업중단 청소년 패널 조사 및 지원방안 연구」의 데이터를 활용하였다. 그 중 5차년도 조사(2017)에 참여한 318명을 대상으로 하였다. 분석을 위해 SPSS 21.0을 활용하였으며 매개효과를 알아보기 위하여 Baron와 Kenny(1986)가 제안한 매개효과 분석단계에 따라 순차적 회귀분석을 실시하였다. 본 연구의 결과는 다음과 같다. 첫째, 진로장애, 자아존중감, 우울, 진로탐색행동은 유의미한 상관관계가 있는 것으로 나타났다. 둘째, 진로장애와 진로탐색행동의 관계에서 자아존중감은 부분 매개효과가 있는 것으로 나타났다. 셋째, 진로장애와 진로탐색행동의 관계에서 우울은 부분 매개효과가 있는 것으로 나타났다. 본 연구를 바탕으로 연구의 논의와 결론을 제시하였으며, 제한점과 후속연구를 위한 제언을 하였다. This study is empirical research intended to test a mediated effect of Self-esteem and depression between career barrier and career exploration behavior of out-of-school youth’ This study utilized data from the 「A Study on the Survey for drop out of school」conducted by the National Youth Policy Institute. The subjects of this study were 318 people who participated in the fifth year survey(2017). SPSS 21.0 was used for the analysis and to find out the mediating effect, sequential regression analysis was conducted according to the mediating effect analysis stage proposed by Baron and Kenny (1986). Based on the results of this study; First, there were statistically significant correlation among in career barrier, Self-esteem, depression, career exploration behavior. Second, there were a partial mediation effect of out-of-school youth Self-esteem in the relationship between career barrier and career exploration behavior. Third, there were a partial mediation effect of out-of-school youth depression in the relationship between career barrier and career exploration behavior. Based on the results, implications and limitations were presented for future studies.

『화타현문내조도(華陀玄門內照圖)』의 약물포제(藥物포製)에 대한 고찰(考察)

심현아 ( Hyun A Sim ),황성연 ( Seong Yeon Hwang ),엄동명 ( Dong Myung Eom ) 대한한의학원전학회 ( 구 대한원전의사학회 ) 2012 대한한의학원전학회지 Vol.25 No.2

Objective: Huatuoxuanmenneizhaotu(華陀玄門內照圖) is a Huatuo`s book in two volumes, The second volume classifies poisonous and nonpoisonous medicines with explaining processing of medicinals. We, authors have concern on processing of medicinals in Huatuoxuanmenneizhaotu. Methods: Through Huatuoxuanmenneizhaotu text translation, we will try to categorize four ways: classifying 1) poisonous and nonpoisonous medicines, 2) methods of making medicines, 3) processing of medicinals using weter and fire and 4) methods of supplements in processing of medicinals. Result: There are some miss-matching in poisonous and nonpoisonous medicines category in Huatuoxuanmenneizhaotucomparing with Bencaogangmu. There are several methods in making medicines, processing of medicinals and supplements in processing of medicinals. Conclusion: These results explain that processing of medicinals in Huatuoxuanmenneizhaotuwere really diverse and various.

Steap4에 의한 지방세포분화 촉진 기전

심현아(Hyun A Sim),신주연(Jooyeon Shin),김지현(Ji-Hyun Kim),정명호(Myeong Ho Jung) 한국생명과학회 2020 생명과학회지 Vol.30 No.12

Six-transmembrane epithelial antigen of prostate 4 (Steap4)는 철과 구리를 환원하여 철과 구리의 세포내 유입에 관여하는 금속 환원효소로, 구리 철의 항상성 뿐만 아니라 염증, 포도당 대사, 지질 대사에도 중요한 역할을 한다. 최근에 Steap4가 지방세포의 분화를 촉진한다는 보고가 발표되었으나, 이에 관련된 분자적 기전에 대해서는 알려지지 않았다. 그래서, 본 연구에서는 Steap4에 의한 지방세포분화 촉진에 관련된 기전을 연구하였다. 이를 위해 3T3-L1 백색지방세포, 불멸화된 갈색지방세포(iBA) 및 생쥐의 배아 섬유아 세포인 C3H10T1/3 세포에서 Steap4을 감소시킨 후 지방세포분화 초기단계에 관련된 신호들을 분석하였다. Steap4을 shRNA로 감소시켰을 때 지방세포분화 초기 단계에서 3종류 지방세포의 세포 증식이 억제되었으며, 세포주기 관련 단백질인 cyclin A, cyclinD 그리고 cdk2의 발현은 감소하는 반면 세포주기 저해 단백질인 p21과 p27의 발현은 증가하였다. 또한 세포주기 관련 신호인 p38, ERK 그리고 Akt의 활성화는 억제되었다. 한편 지방세포분화 초기 단계에 관여하는 지방세포분화 전사인자들을 분석하였을 때, Steap4의 감소는 지방세포분화 활성 전사 인자인 C/EBPβ, KLF4의 발현을 저해하는 반면, 지방세포분화 억제 전사 인자인 KLF2, KLF3 그리고 GATA2의 발현은 증가시켰다. 또한 Steap4의 과발현은 C/EBPβ promoter에 존재하는 전사억제 히스톤 표지자인 H3K9me2과 H3K27me3을 감소시켰다. 따라서, 이상의 결과를 종합하면 Steap4는 지방세포분화 초기단계인 mitotic clonal expansion을 촉진하고 지방세포분화 전사인자들의 발현을 조절함으로써, 지방세포분화를 촉진시킴을 알 수 있었다. The six-transmembrane epithelial antigen of prostate 4 (Steap4) is a metalloreductase that plays a role in intracellular iron and cupper homeostasis, inflammatory response, and glucose and lipid metabolism. Previously, Steap4 has been reported to stimulate adipocyte differentiation; however, the underlying mechanisms of this action remain unexplored. In the present study, we investigated the molecular mechanisms involved in Steap4-induced adipocyte differentiation using 3T3-L1 cells, immortalized brown adipocyte (iBA) cells, and mouse embryonic fibroblast C3H10T1/2 cells. The knockdown of Steap4 using adenovirus-containing shRNA attenuated mitotic clonal expansion (MCE), as evidenced by the impaired proliferation of 3T3-L1 cells, iBA cells, and C3H10T1/2 cells within 48 hr after adding the differentiation medium. Steap4 knockdown downregulated G1/S phase transition-related cell cycle regulators (including cyclin A and cyclin D) and upregulated cell cycle inhibitors (including p21 and p27). Furthermore, Steap4 knockdown inhibited the phosphorylation of p38 mitogen-activated protein kinase, extracellular signal-regulated kinase, and Akt. Moreover, Steap4 knockdown repressed the expression of early adipogenic activators, such as CCAAT-enhancer-binding protein β (C/EBPβ) and Kruppel-like factor family factor 4 (KLF4). On the other hand, Steap4 knockdown stimulated the expression of adipogenic inhibitors, including KLF2, KLF3, and GATA2. The overexpression of Steap4 using an adenovirus removed the repressive histone marks H3K9me2 and H3K9me3 on the promoter of C/EBPβ. These results indicate that Stepa4 stimulates adipocyte differentiation through the induction of MCE and the modulation of early adipogenic transcription factors, including C/EBPβ, during the early phase of adipocyte differentiation.

『식료찬요(食療纂要)』중(中) 오채(五菜)를 이용한 식치(食治) 연구(硏究)

심현아 ( Hyun A Sim ),송지청 ( Ji Chung Song ),엄동명 ( Dong Myung Eom ) 대한한의학원전학회(구 대한원전의사학회) 2011 대한한의학원전학회지 Vol.24 No.5

Objective: 『Sikryochanyo』written by Jeon Soonyi is the first food-Therapy book at Korea. In 『Sikryochanyo』, there are many kinds of food-Therapy including Five-Vegetable therapy. Method: We will try to find out cases of food-therapy with Five-Vegetable in 『Sikryochanyo』. Result: In 『Sikryochanyo』, Five-Vegetable were treated as materia medica widely. Green onion, one of Five-Vegetable as materia medica was the major in use and porridge or soup were the major in frquency. Conclusion: On several types of Five-Vegetable, such as parts or whole, methods to make, the prescription shape etc., there are plenty of usage with its own effectiveness.

『신찬벽온방(新纂辟瘟方)』의 편제(編制)와 내용(內容)에 대한 고찰(考察)

심현아,송지청,금경수,엄동명,Sim, Hyun-A,Song, Ji-Chung,Keum, Kyung-Su,Eom, Dong-Myung 한국의사학회 2013 한국의사학회지 Vol.26 No.2

Objective : "Shinchanbyeokonbang"(printed in 1613) was written by Heo Joon, who is an author of "Dongeuibogam"(also printed in 1613). Even though "Dongeuibogam" has "Onyeok"(chapter for pestilence), Heo Joon wrote technical book for pestilence as name as "Shinchanbyeokonbang". Therefore, we try to compare "Shinchanbyeokonbang" with "Dongeuibogam" "Onyeok". Method : We compared formation and contents of "Shinchanbyeokonbang" with "Dongeuibogam" "Onyeok". Result : "Shinchanbyeokonbang" has entirely new contents than "Dongeuibogam" "Onyeok" in somehow, almost contents of "Dongeuibogam" "Onyeok" are in "Shinchanbyeokonbang" though. Also "Shinchanbyeokonbang" reorganized prescrptions for pestilence not only in "Dongeuibogam" "Onyeok" but also in "Dongeuibogam" ; "Han", "Hwangdal", "Hwa", "Yinhoo", "Hyeol", "Seup" and "Sasoo" Conclusion : "Shinchanbyeokonbang" was printed by Heo Joon at the same time when "Dongeuibogam" was printed in 1613. However, "Shinchanbyeokonbang" has newly formation and contents is some aspects comparing to "Dongeuibogam" "Onyeok", which is the similar chapter for pestilence because this book is the technical book for pestilence.

"화타현문내조도(華陀玄門內照圖)"에 대(對)한 연구(硏究)

심현아,금경수,정헌영,최현배,엄동명,Sim, Hyun-A,Keum, Kyung-Soo,Jung, Hyen-Young,Choi, Hyun-Bae,Eom, Dong-Myung 대한한의정보학회 2012 大韓韓醫情報學會誌 Vol.18 No.1

Objective : "Huatuoxuanmenneizhaotu" is a Huatuo's about 5~6 century works are estimated to be voted for. Scored the first Anatomical Pictures. Expand your knowledge on the anatomy of the later set the foundation. This books is part of two volumes, which is largely divided into six parts. We have concern on the content and features. Method : Through "Huatuoxuanmenneizhaotu" text translation, we will try to categorize two ways : classifying 1) The first volume of Chapter 1, Pictures 2) The second volume divided into four parts, Chapter 2, Viscera Disease and Chapter 3, Viscera metastasize and Chapter 4, Viscera and Bowel each for metastasize, explained. Result : In consideration against Disease symptom classification, Medicine classification, processing of medicinals examine. Viscera Disease symptom each wind pattern(風證), qi pattern(氣證), heat pattern(熱證), cold pattern(冷證), deficiency pattern(虛證) was classified as. Same method were explained as Viscera into Viscera, as Viscera into Bowel. Viscera Disease also not mentioned in the Bowel Disease symptoms were found to be viewed. Conclusion : These results explain "HuatuoXuanmenNeizhaotu" were really diverse and various.

Zigbee와 적외선 센서를 활용한 밸브 개폐 모니터링 시스템 설계 및 구현

심현,오재철,Sim, Hyun,Oh, Jae-Chul 한국전자통신학회 2015 한국전자통신학회 논문지 Vol.10 No.1

화학공장과 같이 위험지역에 설치된 밸브장치는 폭발의 위험을 방지하기 위해 방화 방폭장치로 밀폐되어 있다. 본 논문에서는 방폭장치로 인해 외부전원장치를 사용할 수 없는 밸브장치에 적외선센서와 Zigbee 센서를 이용하여 위험지역의 밸브의 열림도를 측정하여 개폐여부를 확인하고, 밸브 개폐 작동시간을 로그화하여 운전 관리자가 공장을 관리 통제할 수 있는 저전력 모니터링 시스템을 제안한다. 전력관리기능을 적용하기 위해 개선된 비동기LPL 알고리즘을 적용한 전력제어 릴레이보드를 개발하고, 이를 적용한 방폭형 지능형 밸브시스템과 공장 밸브 개폐모니터링 시스템을 설계하고 이를 구현 및 테스트 하였다. The valve device is installed in hazardous areas, such as a chemical plant explosion has been sealed with fire protection device to prevent the risk of explosion. In this paper, due to the explosion-proof devices using external power the device can not be used in infrared sensors and Zigbee sensor valve device by measuring the open degree of valve opening and closing of the danger zone to check whether. Valve opening and closing operation log screen time, we propose a low-power operation monitoring system administrators to manage and control the plant. Develop power control relay board apply an improved algorithm to apply the asynchronous LPL power management. The plant monitoring system and explosion-proof valve opening and closing the valve system with the intelligent device designed and implemented and tested it.

『목과일람(目科一覽)』의 편제(編制)와 내용(內容)에 대한 고찰(考察)

송지청,심현아,금경수,엄동명,Song, Ji-Chung,Sim, Hyun-A,Keum, Kyung-Su,Eom, Dong-Myung 한국의사학회 2013 한국의사학회지 Vol.26 No.2

Objective : The field of specialty in medicine origins from general or comprehensive theories of medicine. "Mokgwaillam" is a book of ophthalmology. However, its contents are from "Dongeuibogam" "Ahn" We need to compare "Mokgwaillam" with "Dongeuibogam" "Ahn" and find out how they are different or similar. Method : Contents comparison between "Mokgwaillam" and "Dongeuibogam" "Ahn" was conducted in contents movement, deletion, transformation and so on. Result : The most content of "Mokgwaillam" derived from "Dongeuibogam" "Ahn" even though "Mokgwaillam" adjusted several parts of "Dongeuibogam" "Ahn" as a book of ophthalmology. Conclusion : Because "Mokgwaillam" contents are not outright and remarkable in ophthalmology field, "Mokgwaillam" has its limit. On the contrast, we suggest that "Mokgwaillam" could represents speciating ophthalmology field in Traditional Korean Medicine. The reason is that "Mokgwaillam" tried to remake "Dongeuibogam" "Ahn" contents as a ophthalmologic book in some aspects ; contents movement, deletion, transformation and so on.