성인의 식이섭취 조사를 위한 반정량 식품섭취빈도조사지의 타당도 연구 -건강증진센터 내원 성인을 대상으로 -

심지선,오경원,서일,김미양,손춘영,이은주,남정모,Shim, Jee-Seon,Oh, Kyung-Won,Suh, Il,Kim, Mi-Yang,Sohn, Chun-Young,Lee, Eun-Joo,Nam, Chung-Mo 대한지역사회영양학회 2002 대한지역사회영양학회지 Vol.7 No.4

This study was conducted to validate the semi-quantitative food frequency questionnaire that was developed to assess the intakes of fatty acids, as well as energy, carbohydrates, fat, protein, minerals and vitamins in Korean adults. The validity of the semi-quantitative food frequency questionnaire was tested on 78 subjects (31 men,47 women) aged 34 to 66 years. The semi-quantitative food frequency questionnaire included 93 food items and was validated on two 3-day dietary records. The mean intakes and the Spearman Correlation Coefficients between the semi-quantitative food frequency questionnaire and the two 3-day dietary records were analyzed for each nutrient and food group level. The mean nutrient intakes obtained from the semi-quantitative food frequency questionnaire were estimated to be greater than those of the two 3-day dietary records. The Spearman Correlation Coefficients between the energy-adjusted nutrient intakes from the semi-quantitative food frequency questionnaire and the two 3-day dietary records ranged from 0.24 for polyunsaturated fatty acids to 0.55 for fat in men and from 0.29 for polyunsaturated fatty acids to 0.55 for saturated fatty acids in women, respectively. The Spearman Correlation Coefficients for food intake ranged from 0.11 for teas and beverages to 0.58 for grains and their products in men,-0.04 for potatoes and starches to 0.73 for milk and dairy products in women. Foods consumed regularly had lower intra-person variation and tended to have higher observed correlation coefficients. These results indicate that the semi-quantitative food frequency questionnaire is a useful tool for estimating nutrient intakes, particularly of total fat and saturated fatty acid intakes.

Self-Reported Diet Management and Adherence to Dietary Guidelines in Korean Adults with Hypertension

심지선,Kyungwon Oh,Sun Jae Jung,Hyeon Chang Kim 대한심장학회 2020 Korean Circulation Journal Vol.50 No.5

Background and Objectives: Although dietary management is strongly recommended in patients with hypertension, little is known about how many manage their diet and follow the guidelines for hypertension. We investigated the prevalence of dietary management among adults with known hypertension and evaluated their compliance to the dietary guidelines. Methods: Data from the Korea National Health and Nutrition Examination Survey 2013–2016 were used. Among 15,870 adults aged 30–79 years, 4,162 reported a physician-diagnosed hypertension. Diet management behavior was defined by self-report response. Actual dietary intake was assessed by a 24-hour dietary recall. Dietary quality was evaluated using the Korean Healthy Eating Index (KHEI). Results: Among adults with hypertension, 28.0% reported that they were managing their diet. Those with hypertension consumed significantly less dietary sodium (p value<0.01), but also less potassium (p value<0.01), resulting in no difference of sodium-to-potassium ratio compared to those without hypertension (p value=0.66). Among those with hypertension, diet-managing adults had better KHEI score (66.9, p value<0.01) and consumed less sodium (3,354.3 mg, p value<0.01) than not-managing adults (63.6 score and 3,554.5 mg, respectively). However, total KHEI score was rather lower in those with hypertension (p value<0.01) than those without hypertension and their sodium intake was still over the recommended amount. Conclusions: More than two-thirds of Korean adults with hypertension did not manage their diet in daily life. More effective strategies are needed to increase the level of compliance with dietary recommendations for people with high blood pressure.

Pt를 대체하는 비귀금속 산화 촉매의 개발

심지선,공민정,장길상,장길남,이후근 한국공업화학회 2012 한국공업화학회 연구논문 초록집 Vol.2012 No.1

Cohort Profile: The Cardiovascular and Metabolic Diseases Etiology Research Center Cohort in Korea

심지선,송보미,이정현,이승원,박지혜,최동필,이명하,하경화,김대중,박성하,이원우,염유식,신의철,김현창 연세대학교의과대학 2019 Yonsei medical journal Vol.60 No.8

Mortalities from cardiovascular disease in Korea have decreased markedly over the past three decades. The major cardiovascularand metabolic risk factors, however, remain prevalent, and their burden on health is large. The Cardiovascular and Metabolic DiseasesEtiology Research Center (CMERC) planned a cohort study in order to identify novel risk factors and to develop evidencebasedprevention strategies of cardiovascular and metabolic diseases. The CMERC deliberately designed two prospective cohorts,a community-based general population cohort (the CMERC cohort) and its sister cohort (a hospital-based high-risk patient cohort),covering a broad spectrum of cardiovascular and metabolic diseases. This paper describes the CMERC cohort study of community-dwelling adults aged 30 to 64 years. A total of 8097 adults completed baseline measurement between 2013 and 2018. Baselinemeasurements assessed socio-demographic factors, medical history, health-related behaviors, psychological health, socialnetwork and support, anthropometry, body composition, and resting blood pressure and comprised electrocardiography, carotidartery ultrasonography, fasting blood analysis, and urinalysis. Both active follow-up through an annual telephone survey and a5-year on-site health examination survey and passive follow-up through secondary data linkage with national databases, such asnational death records, have been applied. Researchers interested in collaborative research may contact the corresponding author.

Cardiovascular and Metabolic Diseases Etiology Research Center (CMERC) cohort: study protocol and results of the first 3 years of enrollment

심지선,송보미,이정현,이승원,박지혜,최동필,이명하,하경화,김대정,박성하,이원우,김현창 한국역학회 2017 Epidemiology and Health Vol.39 No.-

Although the etiologies of cardiovascular disease (CVD) are widely understood, the goal of finding a globally effective solution for preventing CVD is unrealistic. Therefore, we aimed to conduct a community-based prospective study on the prevention and management of CVD in Korean adults. This study was designed to recruit 8,000 healthy adults over the course of 5 years. The baseline assessment includes a wide range of established CVD risk factors, including demographic characteristics, medical history, health behaviors, psychological conditions, body size and composition, blood pressure, the augmentation index, carotid ultrasonography, an electrocardiogram, and biochemical indicators, as well as some novel factors, such as social network characteristics, exposure to environmental pollutants, inflammatory markers, hemostatic markers, and immunosenescence markers. Annual telephone interviews and follow-up health examinations at 5-year intervals after the baseline assessment are planned to collect information on changes in health status and its determinants. Additionally, indirect follow-up using secondary data sources will be conducted to obtain information on health services utilization and death. So far, more than 6,000 adults have been enrolled during the first three and a half years, and almost all participants have been tracked by annual telephone follow-up surveys. The data have been uploaded to iCReaT, the clinical research information management system of the Korea National Institute of Health.

Global analysis of ginsenoside Rg1 protective effects in b-amyloid-treated neuronal cells

심지선,송민영,임성빈,이승은,박강식 고려인삼학회 2017 Journal of Ginseng Research Vol.41 No.4

Background: A number of reports have described the protective effects of ginsenoside Rg1 (Rg1) in Alzheimer’s disease (AD). However, the protective mechanisms of Rg1 in AD remain elusive. Methods: To investigate the potential mechanisms of Rg1 in b-amyloid peptide-treated SH-SY5Y cells, a comparative proteomic analysis was performed using stable isotope labeling with amino acids in cell culture combined with nano-LC-MS/MS. Results: We identified a total of 1,149 proteins in three independent experiments. Forty-nine proteins were significantly altered by Rg1 after exposure of the cells to b-amyloid peptides. The protein interaction network analysis showed that these altered proteins were clustered in ribosomal proteins, mitochondria, the actin cytoskeleton, and splicing proteins. Among these proteins, mitochondrial proteins containing HSD17B10, AARS2, TOMM40, VDAC1, COX5A, and NDUFA4 were associated with mitochondrial dysfunction in the pathogenesis of AD.

Factors associated with dietary adherence to the guidelines for prevention and treatment of hypertension among Korean adults with and without hypertension

심지선,허지은,김현창 대한고혈압학회 2020 Clinical Hypertension Vol.26 No.2

Background: Although dietary modification is strongly recommended for prevention and treatment of hypertension, little is known about which factors are associated with adherence to dietary guidelines. We investigated knowledge and attitude, perceived benefits of, barriers to, and self-efficacy of dietary therapy, and identified the factors associated with dietary adherence among adults with and without hypertension. Methods: We collected information on the knowledge/attitudes and perceived benefits of dietary therapy, as well as barriers to and self-efficacy regarding dietary adherence from 497 middle-aged (34–69 years) adults who participated in the follow-up examination of the Cardiovascular and Metabolic Diseases Etiology Center (CMERC) cohort study during December 2018 and February 2019. Results: Among people without hypertension, 95.5% (343/359) and 95.8% (344/359) answered that they would limit sodium intake and consume health diet, respectively, if diagnosed hypertension. However, among people with hypertension, only 79.7% (110/138) and 77.5% (107/138) reported they were limiting dietary sodium intake and having healthy diet, respectively. Frequency of diet management was not different between normotensive (34.0%) and hypertensive (35.5%) groups. Compared to normotensives, hypertensive people were more likely to have lower dietary adherence score, think they need to change their diet, think dietary change impossible, and report lower self-efficacy for following diet guidelines. Dietary management was significantly associated with cardiometabolic risk factors (OR: 1.63) and dietary education (OR: 2.19) among normotensives, while it was associated only with awareness that lifestyle modification is necessary regardless of antihypertensive medication (OR: 6.29) among hypertensive people. Good dietary adherence had significant associations with perceived barriers (OR: 0.71), selfefficacy (OR: 3.71), and dietary education (OR: 1.98) among normotensives; and with perceived barriers (OR: 0.54), self-efficacy (OR: 4.06), and dietary management (OR: 4.16) among hypertensive people. Conclusions: Many Koreans have relatively low adherence to dietary guidelines for hypertension prevention and treatment. Knowledge, dietary practices, and factors affecting dietary adherence were different between adults with and without hypertension. A targeted approach will be needed to improve blood pressure control of the Korean population.

PGM-Free Diesel 배기가스 처리용 산화촉매 개발 연구

심지선,공민정,장길상,장길남,이후근 한국공업화학회 2013 한국공업화학회 연구논문 초록집 Vol.2013 No.-

식품안정성과 식사섭취의 관련성 : 국민건강영양조사 제3기 (2005년)

심지선(Shim Jee Seon),오경원(Oh Kyungwon),남정모(Nam Chung Mo) 韓國營養學會 2008 Journal of Nutrition and Health Vol.41 No.2

제3기 (2005년) 국민건강영양조사 자료를 이용하어 분석한 결과 연구 대상자의 과반수에서 식품확보가 불안정하였으며, 식품안정성은 식사섭취와 관련이 있어 식품확보가 불안정한 군에서 영양소 섭취량이 낮고 섭취 식품의 다양성이 적었다. 본 연구는 우리 국민의 식품안정성과 식사섭취의 관련성에 대한 거의 초기 연구로 식품확보에 대한 안정성의 문제 크기를 파악하고 식품확보 여부에 따른 식사섭취의 양적 · 질적 측면을 다루었다. 이와 함께 식생활은 건강과 밀접한 관련이 있으므로 식품안정성과 건강 및 질병에 관한 후속 연구가 필요하며, 이러한 연구 결과에 근거하여 향후에는 저소득층의 안정적인 식품확보를 지원하는 정책을 마련하고 시행중인 정책의 효과 평가와 개선 방안을 모색할 필요가 있겠다. Although food insecurity might be associated with poor dietary intake, this relationship has not been researched in Korea. This study examined the association of food security with dietary intake from the third Korea National Health and Nutrition Examination Survey. Food security was measured by a self-reported hunger measure on the dietary situation of subjects' households in the previous year and approximately 2/3 of the subjects lived in food-insecure households. Dietary intake was based on a 24-hour dietary recall. Food insecurity was significantly associated with low nutrients intake and nutrients intake compared to dietary reference intakes (DRI) was also lower among subjects in food-insecure house-holds. Overall diet quality based on dietary diversity score (DDS) was worse in food-insecure subjects. Food security should be considered an important issue to public health because dietary change due to food insecurity may affect health status. (Korean J Nutr 2008; 41 (2): l74~183)

성인 중도지체장애인의 신체적 자기효능감이 정신건강에 미치는 영향 : 회복탄력성의 매개효과를 중심으로

심지선(Sim, Ji Sun),안민권(Ahn, Min Kweon),안진경(Ahn, Jin Kyeong) 학습자중심교과교육학회 2020 학습자중심교과교육연구 Vol.20 No.20

본 연구의 목적은 성인 중도지체장애인의 신체적 자기효능감과 정신건강 간의 관계에서 회복탄력성의 매개효과를 확인하는데 있다. 2018년 8월부터 10월까지 자료를 수집하였고 총 348명의 성인 중도지체장애인이 본 연구에 참여하였다. 신체적 자기효능감, 정신건강 및 회복탄력성은 구조화된 설문지를 사용하여 측정되었으며, 수집된 자료는 SPSS/WIN 25.0으로 분석하였다. 연구 결과 나이(F=9.18, p<.001), 장애등급(F=2.28, p=.046), 직업유무(F=4.97, p=.026)에 따라 정신건강에 통계적으로 유의한 차이가 있었다. 정신건강과 회복탄력성(r=-.14, p<.01) 사이에는 통계적으로 유의한 상관관계가 있었다. 신체적 자기효능감 하위요인 인지된 신체능력, 신체적 자기표현 자신감과 정신건강의 하위요인 불안과 우울, 사회생활 부적응, 신체화 증상과 회복탄력성의 하위요인 자기조절능력, 대인관계능력, 긍정성의 변수들 간의 관계 18개 중에서 5개의 매개효과가 나타났다. 이 연구의 결과는 성인 중도지체장애인의 정신건강을 향상시키기 위해서는 신체적 자기효능감과 회복탄력성을 향상시킬 필요가 있음을 시사한다. The purpose of this study was to test mediating effect of resilience on the relationship between physical self-efficacy and mental health among adults with disabilities in South Korea. Data were collected from August to October, 2018 and a total of 348 adults with disabilities participated in this study. physical self-efficacy, mental health, and resilience were measured using a structured questionnaire. Collected data were analyzed with SPSS 25.0 for windows. As a result of research, there was a statistically significant difference in mental health of participants according to age (F=9.18, p<.001), level of disability (F=2.28, p=.046), and occupation (F=4.97, p=.026). There were statistically significant correlations between mental health and resilience (r=-.14, p<.01). 5 of the 18 mediating effects of the relationship between the physical self-efficacy sub-factor perceived physical ability, physical self-expression confidence and the mental health sub-factor anxiety and depression, social life maladjustment, physicalization symptoms and the resilience sub-factor interpersonal ability, self-control ability, positivity. The results of this study indicate that to improve mental health for adults with disabilities, it is necessary to enhance physical self-efficacy and resilience.