當歸飮子加減을 응용한 乾癬 患者 1例에 대한 臨床的 考察

심상희,김종한,최정화,Shim, Sang-Hee,Kim, Jong-Han,Choi, Jung-Hwa 대한한방안이비인후피부과학회 2002 한방안이비인후피부과학회지 Vol.15 No.1

Psoriasis is a common genetically determined, chronic, inflammatory skin disease characterized by rounded crythematous, dry, scaling patches. It is caused to blood heat(血熱), shortage of blood(血燥) and blood stasis(血瘀) in oriental medicine. We treated a patient who suffered from chroinc and recurred psoriasis, and who was differenciated with endogenous wind due to shortage blood(血燥生風) with Danguiumjagagam(當歸飮子加減). After 10 days of treatment with Danguiumjagagam(當歸飮子加減) and acupunture, we observed an improvement. Based on this experience, it is considered that oriental medicine can be applied to the treatment of psoriasis.

고등학교 피부 미용 교과서 분석 - 국가직무능력표준(NCS)을 중심으로

심상희 한국콘텐츠학회 2022 한국콘텐츠학회논문지 Vol.22 No.5

This study analyzed the problems of skin beauty textbooks used in high school based on the NCS ability unit, and was to improve them. By the NCS standard, it focuses on the contents which can be learned during the high school course. The main results are as follows. First, the revision of textbooks is to contain NCS competency unit, which is excluded in spite of being taught. Second, Replacement is required for NCS 5 level beyond the high school. Third, the illustrated and photographic materials is revised to improve the understanding by maintaining consistency and visibility. Fourth, the contents on the practical skill need specific explanations and instructional materials. Fifth, to revise terminology and the notation system is needed in skin care. The results of this study can be used as basic data to develop an NCS learning module in the skin care field and high school textbooks. 본 연구는 현재 고등학교에서 사용되는 피부 미용 교과서를 NCS 능력 단위를 기준으로, 고등학교 교과서의 문제점과 개선방안에 대해 분석하였다. NCS 기준을 바탕으로 고등학교 과정 동안 습득 가능한 내용의 포함 여부 및 내용의 적합성을 중심으로 분석하였으며 연구의 주요 결과는 다음과 같다. 첫째, 고등학교 기간동안 학습이 가능지만 누락된 NCS 능력 단위를 추가하는 방향으로 개편이 필요하다. 둘째, 고등학교 수준을 벗어난 NCS 능력 단위 5 수준은 교체 작업이 필요하다. 셋째, 삽화 자료와 사진 자료는 학습의 이해를 돕기 위하여 선명도와 일관성을 유지하는 방향으로 개선이 필요하다. 넷째, 교과서의 실습과 관련된 내용들은 구체적인 설명과 이와 관련된 학습자료의 첨부가 요구된다. 다섯째, 피부 미용에서 사용되는 전문용어의 개념 정리와 표기 방식에 대한 논의가 필요하다. 본 연구의 결과는 피부 미용 분야 NCS 학습 모듈 개발과 고등학교 피부 미용 교과서의 개선방안을 모색하는데 기초 자료로 활용될 수 있다. 연구의 한계점으로 학습 대상자의 견해를 반영되지 못한 부분이 있다. 학생들의 교과서에 대한 만족도 및 개선방안에 대한 견해를 살펴보는 후속 연구가 필요할 것으로 생각된다.

Isolation of an Isocoumarin and an Isobenzofuran Derivatives froma Fungicolous Isolate of Acremonium crotocinigenum

심상희,Arlene A. Sy,James B. Gloer,Donald T. Wicklow 대한화학회 2008 Bulletin of the Korean Chemical Society Vol.29 No.4

냉각탑의 수처리 방법

심상희 대한설비공학회 2003 설비저널 Vol.32 No.12

개방 순환식 냉각수 시스템에서 나타나는 금속 부식, 스케일 및 미생물 장애에 대한 화학적 처리 방법에 대하여 설명하고자 한다.

葛根解肌湯을 투여하여 치료한 단독 환자에 대한 임상보고 3례

심상희,정동환,유미경,박수연,최정화,김종한,위통순,Shim, Sang-hee,Jeong, Dong-hwan,Yu, Mi-kyung,Park, Su-yeon,Choi, Jung-hwa,Kim, Jong-han,Wee, Tong-sun 대한한방안이비인후피부과학회 2004 한방안이비인후피부과학회지 Vol.17 No.3

Erysipelas is a type of cellulitis in skin infection generally caused by group A ${\beta}$-hemolytic streptococci. An erysipelas skin lesion typically has a raised border that is sharply demarcated from normal skin. The underlying skin is painful, intensely red, hardened, swollen, and warm. Objectives: We reviewed three cases of erysipelas patients who hospitalized in Dongshin Univ. Suncheon Oriental medicine hospital from June 2001 to June 2002. Methods : We treated them with Galgunhaegitang(葛根解肌湯) for interior diease of Taeumin(太陰人) and also used acupuncture and cupping therapy. Results and Conclusions ; We had significant effects of Galgunhaegitang(葛根解肌湯) for three cases of erysipelas patients. So if the patient were a Taeumin(太陰人), we can consider using Galgunhaegitang(葛根解肌湯) for erysipelas. We can also use antibiotics properly in case there are high fever or open wounds.

보골지 및 염초보골지의 proteasome 저해 작용

심상희,Shim, Sang-Hee 한국생약학회 2008 생약학회지 Vol.39 No.1

Ubiquitin-proteasome proteolytic system plays an important role in selective protein degradation and regulates cellular events including apoptosis. Cancer cells have been shown to be more sensitive to the proapoptotic effects of proteasome inhibition than normal cells. Thus, proteasome inhibitor can be potential anticancer agent. Since the MeOH extracts of psoraleae semen and processed psoraleae semen showed potent proteasome inhibition activity, the fractions of the extracts were evaluated on the activity to screen the proteasome inhibitors. The $CHCl_3$ fr. of the processed psoraleae semen showed the most potent activity, of which chemical investigation led to two coumarins, psoralen and isopsoralen. Their structures were determined by spectroscopic methods such as $^1H-NMR$ and EIMS spectra.

十六味流氣飮의 抗癌 및 抗癌劑 副作用에 미치는 영향

심상희,김종한,최정화,정현우,Shim, Sang-Hee,Kim, Jong-Han,Choi, Jung-Hwa,Jeong, Hyun-Woo 대한한방안이비인후피부과학회 2002 한방안이비인후피부과학회지 Vol.15 No.2

Shibyukmiyouki-Eum was a drug that treated carbuncle and cellulitis. So, the purpose of this study was to investigate effect of Shibyukmiyouki-Eum on the anticancer and inhibitive effects of the secondary effects by anticarcinogen We used Shibyukmiyouki-Eum extract(SYE) with freeze-dried, 8wks-old male mice(balb/c, ICR) and cancer cell lines(L1210. S-180) for this Study, The proliferation of cells was tested using a colorimetric tetrazoliun assay(MTT assay). and measurement of WBC, RBC, hemoglobin and platelet was tested by a automated hematology analyzer. The results of this study were obtained as follow; SYE was showed significantly cytotoxicity on the L1210 and S-180 cell lines. increased proliferation of thymocytes decreased by anticarcinogen. In combined effects of SYE and vincristine(0.005㎎/kg), SYE was significantly inhibited proliferation of L1210 cells and significantly increased proliferation of thymocytes. Also SYE was significantly increased count of WBC. platelet and increased count of RBC, hemoglobin. These results suggest that SYE has not only anticancar action but inhibitive effects of on the secondary effects by anticarcinogen.

내소승마탕(內消升麻湯)의 항암효과(抗癌效果) 연구(硏究)

심상희,박수연,김종한,최정화,Shim, Sang-Hee,Park, Su-Yeon,Kim, Jong-Han,Choi, Jung-Hwa 대한한방안이비인후피부과학회 2006 한방안이비인후피부과학회지 Vol.19 No.1

This study was carried out to evaluate antioxidative, cytotoxic and chemosensitizing effects for anti-tumor activities of Naesosungma-tang (NST). The results were as follows ; 1. The oxidative effects were measured by DPPH radical scavenging activity. NST water extract was showed more effective than ethanol extract and also various solvent fractions from NST showed effective in the following order : butanol fraction > ethyl acetate fraction > hexane fraction > aqueous fraction. 2. NST water extract was showed cytotoxic effects on the human cancer cells Calu-6 cell and SNU-601 cell, but not on MCF-7 cell. 3. The viability of cells was measured in 4 kinds of solvent fractions from water extract of NST by MTT assay. The results were as followings : 1) On the NIH3T3 cell, $IC_{50}$ value was $200{\sim}300\;{\mu}g/m{\ell}$ in three fractions except aqueous fraction. 2) On the Caco-2 cell, effective only in the butanol fraction. 3) On the Calu-6 cell, most effective in hexane fraction($IC_{50}:80\;{\mu}g/m{\ell}$) and effective in ethyl acetate and butanol fraction($IC_{50}:100{\sim}120\;{\mu}g/m{\ell}$). 4) On the MCF-7 cell, $IC_{50}$ value was similar in three fractions except aqueous fraction. 5) On the SNU-601 cell, $IC_{50}$ value was within $100\;{\mu}g/m{\ell}$ in three fractions except aqueous fraction. 6) On the HCT-1l6 cell, $IC_{50}$ value was $150{\sim}200\;{\mu}g/m{\ell}$ in three fractions except aqueous fraction. 7) On the AML-2/WT cell, not effective in four kinds of solvent fractions. 4. In combined effects of NST and vincristine on AML-2/D100 cell, water and ethanol extracts of NST and hexane fraction of water extracts of NST more effectively inhibited proliferation of AML-2/D100 cell. These results Suggest that NST has antioxidative and cytotoxic effects against Caco-2, Calu-6, MCF-7, SNU-601, HCT116 and NIH3T3 cell especially Calu-6 and SNU-601 cell, and also chemosensitizing effects against AML-2/D100 cell in combined vincristine.

淸肌散加減을 응용한 한포진 환자 치험 1례

심상희,정동환,김종한,최정화,박수연,Shim, Sang-hee,Jeong, Dong-hwan,Kim, Jong-han,Choi, Jung-hwa,Park, Soo-yeon 대한한방안이비인후피부과학회 2003 한방안이비인후피부과학회지 Vol.16 No.3

Dyshidrotic eczema is a eczema making vesicles at the hand and foot with pruritus, tend to chronically recurred. It is caused to retention of Damp-heat in interior(濕熱蘊積), interior heat due to Yin deficiency(陰虛內熱) in Oriental medicine. We treated a patient who suffered from recurred dyshidrotic eczema differentiated with retention of Damp-heat in interior(濕熱蘊積) with Chunggisangagam(淸肌散加減). After about 30 days of treatment with Chunggisangagam(淸肌散加減), acupunture and aroma therapy, we observed an improvement. Based on this experience, it is considered that the Oriental medicine can be applied to the treatment of dyshidrotic eczema.

부모양육태도가영아정서지능발달에미치는영향

심상희,홍미라,김동진 전국상담복지학회 2019 전국상담복지연구 Vol.3 No.-

가정은 영아들의 사회성이 형성되는 곳으로 가정에서의 부모의 교육과 역할은 매우 중요하다. 그러나 급격한 산업화로 인한 사회변화 현상으로 여성의 사회진출은 증가하고 가정은 기능에서 많은 변화를 가져왔다. 본 연구의 목적은 어머니의 양육태도와 아버지의 양육태도가 정서지능에 미치는 영향을 알아보고 영아 시기는 정서 지능을 발달시키는데 중요한 시기임을 알고 좀 더 영아의 정서 지능에 관련된 연구가 폭넓게 마련될 필요가 있다. 본 연구의 방법은 문헌연구를 통한 실증적 연구를 시행하였다. Home is where the social nature of infants is formed and parents' education and role in the home is very important. However, due to the social changes caused by rapid industrialization, women's advancement into society increased and families brought about many changes in function. The purpose of this study is to find out the effect of mother's upbringing and father's upbringing on emotional intelligence, to find out that the infant period is an important time for developing emotional intelligence, and more studies related to the emotional intelligence of infants need to be made widely. The method of this study was to conduct empirical research through the study of literature.