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      • KCI등재

        Fe80 B12 Si8 비정질 합금에 Cr 첨가가 자기적 성질에 미치는 영향

        신찬수,송진태 대한금속재료학회(대한금속학회) 1986 대한금속·재료학회지 Vol.24 No.11

        The effect of Cr element and heat treatment on the physical and magnetic properties of Fe_(80)B_(12)Si_8 (at.%) amorphous alloy which has a high saturation magnetization and a low core loss was investigated in this study. The (Fe_(1-x)Cr_x)_(80)B_(12)Si_8 (x= 0-0.10) amorphous allay ribbons were fabricated by single roller method and annealed for 20 minutes at various temperatures below the crystallization temperature in Ar gas atmosphere. With increasing Cr contents, it was found that crystallization temperature increased from 472℃ to 490℃ and soft magnetic properties were improved. The coercive force decreased and the maximum permeability increased with increasing Cr contents. These improvements may be attributed to the decreasing of magnetostriction by Cr addition to Fe_(80)B_(12)Si_8 alloy. The annealing treatment improved the soft magnetic properties of Fe_(1-x)Cr_x)_(80)B_(12)Si_8 amorphous alloys and the optimum annealing temperature was 60℃ lower than the crystallization temperature. Coercive force and high frequency magnetic properties of (Fe_(0.96)Cr_(0.04))_(80)B_(12)Si_8 amorphous alloy that was annealed at 425℃ for 20 minutes were comparable to a zero magnetostrictive Co-based alloy.

      • SCOPUSKCI등재
      • KCI등재
      • KCI등재

        The Risks and Benefits of Calcium Supplementation

        신찬수,김경민 대한내분비학회 2015 Endocrinology and metabolism Vol.30 No.1

        The association between calcium supplementation and adverse cardiovascular events has recently become a topic of debate due to the publication of two epidemiological studies and one meta-analysis of randomized controlled clinical trials. The reports indicate that there is a significant increase in adverse cardiovascular events following supplementation with calcium; however, a number of experts have raised several issues with these reports such as inconsistencies in attempts to reproduce the findings in other populations and questions concerning the validity of the data due to low compliance, biases in case ascertainment, and/or a lack of adjustment. Additionally, the Auckland Calcium Study, the Women’s Health Initiative, and many other studies included in the meta-analysis obtained data from calcium-replete subjects and it is not clear whether the same risk profile would be observed in populations with low calcium intakes. Dietary calcium intake varies widely throughout the world and it is especially low in East Asia, although the risk of cardiovascular events is less prominent in this region. Therefore, clarification is necessary regarding the occurrence of adverse cardiovascular events following calcium supplementation and whether this relationship can be generalized to populations with low calcium intakes. Additionally, the skeletal benefits from calcium supplementation are greater in subjects with low calcium intakes and, therefore, the risk-benefit ratio of calcium supplementation is likely to differ based on the dietary calcium intake and risks of osteoporosis and cardiovascular diseases of various populations. Further studies investigating the risk-benefit profiles of calcium supplementation in various populations are required to develop population-specific guidelines for individuals of different genders, ages, ethnicities, and risk profiles around the world.

      • KCI등재후보

        Dikkopf-2, -3 and -4 Enhance Early Osteoblastic Differentiation in Mouse Mesenchymal Progenitor Cells and Stimulate Apoptosis in Osteoblastic Cells

        신찬수,조선욱,정주연,선현진,양재연,김상완,김성연 대한골대사학회 2011 대한골대사학회지 Vol.18 No.2

        Objectives: The inhibitory effect of Dickkopf (Dkk)-1 on osteoblastic differentiation through blocking Wnt signaling has been well studied. However, the role of other members of the subfamily of Dkks remains unclear. We have examined the role of different Dkks on osteoblastic differentiation of mesenchymal progenitor cells and apoptosis of osteoblasts. Methods: Osteoblastic differentiation was induced by treatment of Wnt-3a with Dkks or vehicle in C3H10T1/2 cells and alkaline phosphatase (ALP) activity was measured. Serum deprivation induced apoptosis was performed with pre-treatment of Dkks or vehicle in MC3T3-E1 cells and methyl thiazolyl tetrazolium (MTT) assay was done. Results: Dkk-2 at low concentrations (5 and 20 nM) and Dkk-3, -4 at any concentrations (5 to 100 nM) significantly increased Wnt-3a-induced ALP activity, whereas Dkk-2 at high concentration (100 nM) significantly reduced. Treatment of Dkk-2, -3 and -4 at high concentration (100 nM) showed significant decreases of Wnt/β-catenin transcriptional activity,whereas no effects were seen at low concentration (20 nM). In parallel experiments, treatment of Dkk-1 showed robust dose dependent inhibition not only in ALP activity but also in Wnt/β-catenin transcriptional activity. Dkk-2, -3 and -4 increased serum deprivation-induced apoptosis in MC3T3-E1 mouse osteoblasts, while Dkk-1 had no effect. Conclusions: We found that unlike Dkk-1, Dkk-3 and -4 stimulated early osteoblastic differentiation at various concentrations regardless of their inhibitory effects on Wnt/β-catenin transcriptional activity at high concentration. Dkk-2 had a biphasic effect where the lower doses significantly increased ALP activity while the high dose was inhibitory. Dkk-2, -3 and -4stimulated osteoblast apoptosis whereas Dkk-1 had no effect. [Korean Journal of Bone Metabolism, 18(2): 101-110, 2011]

      • KCI등재

        내장형 모노폴 안테나 설계 및 SAR분석

        신찬수,신호섭,김남,최재익,박주덕,Shin Chan-Soo,Shin Ho-Sub,Kim Nam,Choi Jae-Ic,Park Ju-Derk 한국전자파학회 2004 한국전자파학회논문지 Vol.15 No.12

        본 논문에서는 여러 구조 및 파라미터 변경을 통하여 SAR을 저감시킬 수 있는 PCS, IMT-2000 대역과 무선랜대역을 포함하는 평면 모노폴 안테나를 설계하였다. 설계를 위하여 안테나 특성 및 SAR에 영향을 미칠 수 있는 여러 가지 변수들을 고려하여 최적화 하였다. 이를 통해 원하는 대역폭과 만족할만한 SAR 값을 갖는 평면 모노폴 안테나를 설계하였다. 설계된 안테나를 제작된 휴대폰에 탑재하여 시뮬레이션 하였다. 그 결과 SAR 값은 1 g및 10g 평균 첨두치가 0.656, 0.387 W/kg이었다. 이 결과를 바탕으로 실제 측정장에서 동일한 조건으로 SAR을 측정하였다. 그 결과 내장형 평면 모노폴 안테나를 탑재한 휴대폰의 경우 0.686 W/kg(1 g 기준), 0.356 W/kg(10 g 기준)의 결과를 얻었고, 외장형 모노폴 안테나의 경우는 1.33, 0.812 W/kg이 나와 내장형 평면 모노폴 안테나의 SAR 값이 약 $50\%$ 낮은 결과를 얻었다. In this paper, meander-line planar monopole antenna mounted on PCS/IMT-2000/WLAN handset for SAR reduction is designed. Frequency characteristics and SAR value optimized with various design parameters are analyzed and designed. Designed internal monopole antenna mounted on the handset is simulated. The 1 g and 10 g peak average SARs of internal monopole antenna are 0.656 and 0.387 W/kg respectively. And internal monopole antenna and external monopole antenna attached on the handset are tested. As a result, internal monopole antenna 1 g and 10 g peak average SARs are 0.686 and 0.356 W/kg. And external monopole antenna's results are 1.33 and 0.812 W/kg, respectively. So internal monopole antenna has a about $50\%$ SAR reduction in comparison with external monopole antenna.

      • KCI등재

        노인 남성 골다공증의 접근과 치료

        신찬수 대한임상노인의학회 2005 대한임상노인의학회지 Vol.6 No.1

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