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      • KCI등재

        내장형 모노폴 안테나 설계 및 SAR분석

        신찬수,신호섭,김남,최재익,박주덕,Shin Chan-Soo,Shin Ho-Sub,Kim Nam,Choi Jae-Ic,Park Ju-Derk 한국전자파학회 2004 한국전자파학회논문지 Vol.15 No.12

        본 논문에서는 여러 구조 및 파라미터 변경을 통하여 SAR을 저감시킬 수 있는 PCS, IMT-2000 대역과 무선랜대역을 포함하는 평면 모노폴 안테나를 설계하였다. 설계를 위하여 안테나 특성 및 SAR에 영향을 미칠 수 있는 여러 가지 변수들을 고려하여 최적화 하였다. 이를 통해 원하는 대역폭과 만족할만한 SAR 값을 갖는 평면 모노폴 안테나를 설계하였다. 설계된 안테나를 제작된 휴대폰에 탑재하여 시뮬레이션 하였다. 그 결과 SAR 값은 1 g및 10g 평균 첨두치가 0.656, 0.387 W/kg이었다. 이 결과를 바탕으로 실제 측정장에서 동일한 조건으로 SAR을 측정하였다. 그 결과 내장형 평면 모노폴 안테나를 탑재한 휴대폰의 경우 0.686 W/kg(1 g 기준), 0.356 W/kg(10 g 기준)의 결과를 얻었고, 외장형 모노폴 안테나의 경우는 1.33, 0.812 W/kg이 나와 내장형 평면 모노폴 안테나의 SAR 값이 약 $50\%$ 낮은 결과를 얻었다. In this paper, meander-line planar monopole antenna mounted on PCS/IMT-2000/WLAN handset for SAR reduction is designed. Frequency characteristics and SAR value optimized with various design parameters are analyzed and designed. Designed internal monopole antenna mounted on the handset is simulated. The 1 g and 10 g peak average SARs of internal monopole antenna are 0.656 and 0.387 W/kg respectively. And internal monopole antenna and external monopole antenna attached on the handset are tested. As a result, internal monopole antenna 1 g and 10 g peak average SARs are 0.686 and 0.356 W/kg. And external monopole antenna's results are 1.33 and 0.812 W/kg, respectively. So internal monopole antenna has a about $50\%$ SAR reduction in comparison with external monopole antenna.

      • KCI등재후보

        한국인 성인 당뇨병의 병인론적 이형성

        신찬수(Chan Soo Shin),박용수(Yong Soo Park),김용성(Yong Sung Kim),김성연(Seong Yeon Kim),조보연(Bo Youn Cho),이홍규(Hong Kyu Lee),고창순(Chang Soon Koh),민헌기(Hun Ki Min),이병두(Byoung Doo Rhee),이기업(Ki Up Lee) 대한내과학회 1991 대한내과학회지 Vol.40 No.1

        N/A One hundred and twenty-one Korean adult diabetic patients with recent onset, diagnosed between the ages of 30 and 77 years, were investigated for the parameters of glycemic control, islet cell function, and immunologic markers of insulitis. The antibody tests were compared to the results of the 40 nondiabetic controls matched for age and body mass index (BMI). The 12 (9.9%) diabetic subjects were found to have positive islet cell surface antibody (ICSA). These patients were characterized by a small basal insulin reserve, more ketonuria, and poor glycemic control, although the maleness, the age at onset, and the duration of diabetes were the same as in 109 ICSA-negative cases. However, 11 patients (10.2%) having insulin autoantibody (IA) presented less basal and stimulated C-peptide reactivities, while other parameters compared were not different from those of IA-negative patients. Twelve patients were treated with insulin during follow-up for better glycemic control. Insulin-treated patients included those with poor glycemic control, more ketonuria, more proteinuria, longer duration of diabetes, and lower basal and stimulated C-peptide level, while the age of onset, the amount of weight loss, and the duration of diabetes were the same as in 87 cases treated without insulin. From these observations, it is suggested that 1) a significant number of Korean adult diabetic patients, who have not been treated with insulin initially, require insulin to control their high blood glucose levels: 2) about 17% of the middle-aged diabetic patients, who were diagnosed after the age of 30 are autoantibody positive suggesting autoimmune in etiology: 3) low C-peptide response after glucagon stimulation may be useful in predicting insulin deficiency when combined with ICSA and IA.

      • KCI등재후보

        당뇨유발 백서에서 △6 탈포화효소의 활성도 및 지방산 구성

        신찬수(Chan Soo Shin),이문규(Moon Kyu Lee),한은경(Eun Kyung Han),고경수(Kyung Soo Ko),김철희(Chul Hee Kim),김성연(Seong Yeon Kim),조보연(Bo Youn Cho),이홍규(Hong Kyu Lee),고창순(Chang Soon Koh),민헌기(Hun Ki Min) 대한내과학회 1992 대한내과학회지 Vol.43 No.2

        N/A Microsomal △6 desaturase is a key enzyme in the metabolism of polyunsaturated fatty acids, the activity of which is regulated by insulin. To determine if changes in d △6 desaturase activity in experimental diabetes correspond to changes in fatty acid compoistion of microsome and RBC membrane, 18 Sprague-Dawley rats were studied for 6 weeks. The animals were divided into 3 groups with 6 rats in each group. The first group was the contrals, the 2nd 3rd groups were streptozotocin diabetic rats but insulin was injected to the 3rd group. The △ 6 desaturase activities of diabetic rats were 68pg of those of controls (p<0.05) and increased to 119% of controls (p<0.05) with insulin treatment. Linolic (LA), palmitic (PA) and docosahexaenoic acids (DHA) were increased and arachidonic (AA) & oleic acids (OA) decreased in liver microsome of diabetic rats, which were reversed with insulin treatment, respectively. In erythrocyte membrane LA & stearic acids (SA) were increased, and PA, AA, and palmitoleic acids were decreased which were not reversed with insulin treatment, however. To summarize, insulin controls the △ 6 desaturase activities, which in turn affect fatty acid compositions of microsome and RBC membranes. Theee findings suggest that adequate insulin therapy is required for the correction of the polyunsaturated fatty acid metabolism as well as blood glucose control in the insulin dependent diabetics.

      • KCI등재

        건강보험데이타베이스를 이용한 골다공증성 고관절 골절 식별 및 타당도

        박찬미 ( Chan Mi Park ),장선미 ( Sun Mee Jang ),장수현 ( Su Hyun Jang ),하용찬 ( Yong Chan Ha ),이영균 ( Young Kyun Lee ),윤현구 ( Hyun Koo Yoon ),신찬수 ( Chan Soo Shin ),김덕윤 ( Deog Yoon Kim ),이성수 ( Seong Su Lee ),최형진 ( 대한고관절학회 2010 Hip and Pelvis Vol.22 No.4

        Purpose: The aim of this study was to develop and validate identification criteria for the cases of osteoporotic hip fracture using the National Health Insurance Database, and we calculated the incidence rate of osteoporotic hip fracture in the Korean population using these criteria. Materials and Methods: The criteria to identify osteoporotic hip fracture using a diagnosis code, a procedure code, the type and number of medical service usages and the patients` ages were developed via discussions among experts. These criteria were validated by using a hip fracture cohort in which all the genuine osteoporotic hip fracture patients in the Jeju area were identified by reviewing the registered medical records and radiographs. By applying the identification criteria to the National Health Insurance Database that was accumulated until June 2009, we calculated the incidence rate of osteoporotic hip fracture in patients between 50 and 100 years of age in 2008. Results: The identification criteria had a sensitivity of 93.1% and a positive predictive value of 77.4%. A total of 20,432 osteoporotic hip fracture cases were identified in 2008, and the incidence rate was 15.7 cases per 10,000 persons. The osteoporotic hip fracture incidence rate for females was 20.7 (per 10,000persons), and this was 2.1 times higher than that for the males (9.8case per 10,000persons), and the rates were increased with age. Conclusion: The incidence of osteoporotic hip fracture that occurred on a nationwide scale can be more precisely estimated by using the National Health Insurance Database with its comprehensive information on the overall details of treatment as well as the diagnosis codes, and so the incidence of osteoporotic hip fracture can be reliably calculated for each year. The results from this research could be used as evidence in a hip fracture management plan for establishing Korean Health policy.

      • KCI등재

        난소기능이 소실된 여성에서 혈청 인슐린유사 성장인자 결합단백질의 양상과 골밀도의 연관성function

        문신용(Shin Yong Moon),최영민(Young Min Choi),김석현(Seok Hyun Kim),이진용(Jin Yong Lee),김정구(Jung Gu Kim),신찬수(Chan Soo Shin),서창석(Chang Seok Suh),김성연(Seong Yeon Kim) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.1

        N/A The insulin-like growth factor(IGF)s are believed to play an important role in the maintenance of bone mass. The IGFs are found complexed with high affinity to a family of IGF-binding protein(IGFBP)s in the circulation. It is known that IGFBPs are involved in the transport of IGFs to tissues and modulate IGFs actions at local tissue The purposes of this study were to compare serum IGFBPs profiles in natural menopausal women with and without osteoporosis and in osteoporotic and nonosteoporotic women with premature menopause and to evaluate the relationship between serum IGFBPs profiles and bone mineral density(BMD) in women without ovarian function. Serum IGFBPs were measured by western ligand blot and immunoradiometric assay. The relative levels and proportions of serum IGFBP-2 measured by western ligand blot in natural menopausal women with osteoporosis(n=20) significantly increased compared to nonosteoporotic women(n= 20), whereas relative levels of serum IGFBP-3 in natural menopausal women with osteoporosis decreased. No significant differences in the relative levels of serum IGFBPs between osteoporotic(n=8) and nonosteoporotic women(n=10) with premature menopause were noted. The IGFBP-3 levels determined by immunoradiometric assay in women without ovarian function(n= 69) showed a similiar trend. The relative proportions of serum IGFBP-2 in osteoporotic women without ovarian function were signifcantly higher than those in nonosteoporotic women whereas relative levels of serum IGFBP-3 in osteoporotic women with natural menopause decreased. The relative levels and proportions of serum IGFBP-2 in women without ovarian function correlated negatively with BMD of lumbar spine, trochanter and Ward's triangle but there were significant positive correlations between levels and relative proportions of serum IGFBP-3 and BMD of above sites. No significant correlations between relative levels and proportions of serum IGFBP-1, IGFBP-2 and BMD were noted. Our data indicate that serum IGFBP profiles might be useful in identifying women without ovarian funcion at risk for osteoporosis,

      • 3차원 시청각환경제시기의 현실감 평가 실험

        서형준 ( Hyung Jun Seo ),신찬수 ( Chan Soo Shin ),장상절 ( Sang Cheol Jang ),박경동 ( Kyung Dong Park ),고희동 ( Hee Dong Ko ) 한국감성과학회 1998 추계학술대회 Vol.1998 No.-

        본 논문은 감성측정평가 시뮬레이터 구축의 일환으로 개발한 3차원 시청각 환경 제시기가 생성하는 가상환경의 현실감 정도를 평가하는 데 목적이 있다. 이를 위하여 가상환경의 최소 구성성분요소들로 Size, Length, Distance 등을 설정하였으며, 이들에 대하여 가상환경과 실제환경에서 각각 실험을 통해 피실험자들의 인식전도를 측정하였다. 실험에서 사용한 측정방법은 가상세계에 대한 인식실험을 위해 개발된 Size/Distance Estimation, Sketch Map, Object Search 방법 등을 사용하였으며, 가상환경과 실제환경에서 각각 도출된 실험결과의 차이를 토대로 3차원 시청각 환경 제시기의 현실감 수준을 평가하였다. 본 실험을 위해 구성한 피실험자의 집단은 컴퓨터 사용에 익숙한 20대 이공계열 84명(남:56, 여:28)의 학생들을 대상으로 하였다. 본 논문의 의의로는 3차원 시청각 환경 제시기가 생성하는 가상환경의 현실감 수준을 평가함으로써 개발 시스템의 보완 및 발전과 본격적인 감성공학 분야의 활용을 위한 지침을 마련하는데 있다.

      • 한국 여성에서 비만과 우울증의 연관성

        윤대현,박진호,이철민,신찬수,조상헌,오병희,Yoon, Dae-Hyun,Park, Jin-Ho,Lee, Cheol-Min,Shin, Chan-Soo,Cho, Sang-Heon,Oh, Byung-Hee 한국정신신체의학회 2007 정신신체의학 Vol.15 No.1

        연구목적 : 비만과 우울증은 모두 심각한 공공 의료 문제이고 특히 주된 심혈관계 질환 위험인자이다. 비만과 우울증 상에 관한 해외 연구는, 일정한 결론은 아니나, 여러 연구에서 연관성 존재를 보고하고 있고 특히 일부 연구는 여성에서 그 연관 정도가 큼을 보고 한 바 있다. 본 연구는 한국 여성에서 있어 비만, 특히 복부비만과 우울증상의 연관성을 분석하고자 한다. 방법: 여성 연구 대상자 4,609명을 대상으로 Beck 우울 척도 및 체계측을 시행한 결과를 이용 우울증상과 비만과의 연관성을 분석하였다. 비만도는 체질량지수로 정하였으며 체질량지수 $25kg/m^2$ 이상을 비만으로 하였고 복부비만은 허리둘레 85cm 이상으로 정의하였다. 임상적으로 우울증을 의심할 수 있는 Beck 우울척도 분할점은 16점으로 하였다. 결과: 정상 체중군에 비해 비만 여성군에서 우울 여성의 비율이 유의미하게 높았고(27.6% VS. 23.2%, p<0.01), 복부 비만 여성에서도 우울 여성군의 비율이 통계적으로 유의하게 높았고(26.9% VS. 22.7%, p<0.01), 비만 여성군 중 우울 여성에서 복부 비만 가진 비율이 통계적으로 유의미하게 높았다(93.2% VS. 86.9%, p<0.01). 결론 : 본 연구의 결과는 한국 여성에서 비만, 특히 복부비만과 우울증간 연관성이 존재함을 보였고 향후 전향적 연구를 통한 비만과 우울증간 상호 역할에 대한 적극적 이해가 필요함을 시사한다. Backgrounds: Obesity and depression are serious health problem and also constitute cardiovascular disease risk factors. Some studies found an association between obesity and higher rates of depression in women but not in men. The current study examined the association between depressive symptoms and obesity, especially central obesity in Korean women. Methods : The participants were 4,609 Korean women aged 20-85 years. Each individual was assessed for the presence of obesity and central obesity using the criteria suggested by WPRO(World Health Organization Regional Office for the Western Pacific). Depressive symptomatology was measured by Beck Depression Inventory(BDI). Results : In obese women, rate of depressed women is significantly higher compared normal group(27.6% VS. 23.2%, p<0.01). The rates of depressed women is higher in women who had central obesity(26.9% VS. 22.7%, p<0.01). Depressed women had higher rates of central obesity(93.2% VS.86.9%, p<0.01). Conclusion Our findings show obesity especially central obesity is associated with depressed women and suggests that further investigation for interaction between depression and obesity is needed.

      • 한국 여성에서 우울증상과 혈당 조절의 연관성

        윤대현,박진호,박민정,신찬수,조상헌,오병희,Yoon, Dae-Hyun,Park, Jin-Ho,Park, Min-Jeong,Shin, Chan-Soo,Cho, Sang-Heon,Oh, Byung-Hee 한국정신신체의학회 2006 정신신체의학 Vol.14 No.1

        연구목적 : 우울증상은 여성에게 흔하며 적절한 혈당 조절은 당뇨병 치료에 있어 매우 중요하다. 당뇨병 환자에서 우울증은 상대적으로 흔히 발견된다. 그러나 아직 우울증과 혈당조절의 상호관계에 대해서는 명확히 밝혀진 바가 없다. 본 연구는 한국 여성 당뇨병 환자의 혈당 조절과 우울증상 사이의 상호관계를 평가하려 한다. 방법: 여성 당뇨병 환자 216명을 포함한 연구 대상자 4,567명을 대상으로 Beck 우울 척도와 장기 혈당조절 지표인 $HbA_{1c}$ 수치를 측정하여 우울증과 혈당조절간의 연관성을 분석하였다. 공복 혈당 수치와 비만도 지표인 체질량지수도 함께 측정하여 분석하였다. 임상적으로 우울증을 의심할 수 있는 분할점은 16점으로 하였다. 결과: 당뇨병 보유 여성군에서 우울 여성군이 유의미하게 많았고(P<0.001), Beck우울 척도 평균치도 통계적으로 유의하게 높았다(p<0.001). 우울 여성군에서 $HbA_{1c}$, 평균치 (p<0.01)와 공복 혈당 평균치 (p<0.05)가 유의미하게 높았고, 혈당 조절의 장애가 심할 수록 우울 여성군의 비율이 증가하는 경향을 보였다(p=0.001). 결론: 본 연구는 한국 여성에서 우울증상과 당뇨병 및 혈당 조절간 연관성이 존재함을 지지하는 결과를 보였다. 향후 종적 연구를 통한 우울장애와 당뇨병간 상호작용에 대한 원인-결과론적 이해가 요구된다. Backgrounds : Depression has been prevalent in women and maintaining optimal glycemic control is an important goal of diabetes management. Although depression is common in adults with diabetes, its relationship to glycemic control remains unclear, espacilly in Korean women. The current study examined the relationship of depressive symptomatology with glycemic control in Korean women. Methods : Beck depression inventory (BDI), $HbA_{1c}$ as an index of long-term glycemic control, fasting glucose level and body mass index (BMI) were measured in sample of 4,567 women of whom 4.7%, 216 women had diabetes, and the relationship between depression and glycemic control was analyzed. BDI Scores of 16 and above is a cut off point to indicate possible clinical depression. Results The frequency of depressed women (p<0.001) and the mean score of BDI (p<0.001) were significantly higher in diabetic women. The mean level of $HbA_{1c}$ (p<0.01) and fasting glucose (p<0.05) were higher in depressed women. There was a graded relationship between the percentile of depressed women and a degree of glycemic control impairment (p=0.001). Conclusion : The current study found the relationship of depressive symptomatology with glycemic control in Korean women. This relationship may be mediated by decreased self-care behaviors or by neurobiological dysregulation. Improving identification and treatment of depression in women with diabetes might have favorable effects on diabetic outcomes.

      • KCI등재후보

        당뇨병환자의 적혈구막 인지질지방산의 변화

        장학철(Hak Chul Jang),박경수(Kyong Soo Park),홍성관(Sung Kwan Hong),신찬수(Chan Soo Shin),한은경(Eun Kyung Han),이문규(Moon Kyu Lee),김성연(Seong Yeun Kim),이홍규(Hong Kyu Lee),고창순(Chang Soon Koh),민헌기(Hun Ki Min),이병두(Byoung 대한내과학회 1990 대한내과학회지 Vol.39 No.5

        N/A Several differences in phospholipid fatty acid composition of the erythrocyte membrane have been reported in diabetes mellitus, and these remain controversial. To evaluate the dietary fat intake pattern and the fatty acid metabolism in Korean diabetic patients, fatty acids in the erythrocyte membrane were determined by gas-liquid chromatography in 10 subjects with IDDM, 36 subjects with NIDDM, and 37 control subjects. Significant increases in palmitic acid (p<0.01) and oleic acid (p <005) were observed in erythrocytes from IDDM patients. Significant increases in myristric acid (p<0. 05), palmitic acid (p<0.01), and oleic acid (p<0.05), along with significant decreases in docosahexaenoic acid (p<0.01), were observed in erythrocytes from nonobese NIDDM patients, Similar fatty acid compositions in erythrocytes were noticed in obese NIDDM patients, except for eicosadienoic acid. The P/S ratios in the erythrocyte membrane fatty acids were significantly lower in diabetic patients than in the controls (0.92±0.03 vs 1.01±0.02, p<0.05 in IDDM; 0.85±0.03 vs 0.99±0.02, p<0.01 in nonobese NIDDM; 0.81±0.07 vs 0.99±0.02, p<0.05 in obese NIDDM). The arachidonic: linoleic acid ratio and oleic: stearic acid ratio in the erythrocyte membrane were not different between the diabetic patients and the controls, but the eicosapentaenoic: docosahexaenoic acid ratio was lower in the NIDDM patients than in the controls. These results suggest that an increase in the peroxidation of fatty acids in the erythrocyte membrane might result in a decrease of polyunsaturated fatty acids, especially DHA, and since membrane fatty acids are modified by receut dietary fat intake, we should be concerned about diet therapy, especially fat intake in diabetes. Fish oil supplements in diabetic patients should also be used with caution.

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