조리방법을 달리한 쥐눈이콩의 항산화력 및 이소플라본 배당체·비배당체 함량 비교

신지훈,주나미,Shin, Jihun,Joo, Nami 한국식품조리과학회 2016 한국식품조리과학회지 Vol.32 No.2

Purpose: In this study, small black beans (Rhynchosia nulubilis) that were produced in the Jungsun province of South Korea were selected for use in various cooking recipes because they are known to contain higher isoflavones and excellent antioxidant effects, as compared to any other domestic soybeans. Methods: Physicochemical and antioxidant characteristics of small black beans were analyzed with uncooked beans and four other cooking methods of pan broiling, boiling, steaming, and pressure cooking. Results: Contents of ${\beta}$-glucosides (daidzin, glycitin, and genistin) and aglycone (daidzein, glycitein, and genistein) in small black beans were significantly different depending on the cooking methods (p<0.001). The results of the experiment indicated that the amount of total polyphenol in pressure cooked beans was highest, showing a value of 7.16 mg/g (p<0.001). Most contents of isoflavones (${\beta}$-glucoside, aglycone) in uncooked beans appeared to increase after cooking. In particular, the amount of glycitein was highest in pan broiled beans ($9.63{\mu}g/g$). The total isoflavone content differed among the different cooking methods, ranging from highest to lowest in the following order : pan broiled beans ($759.49{\mu}g/g$), pressure cooked beans ($725.12{\mu}g/g$), boiled beans ($591.05{\mu}g/g$), steamed beans ($511.61{\mu}g/g$), and uncooked beans ($180.80{\mu}g/g$) (p<0.001). Conclusion: Especially, the amount of isoflavones increased significantly in pan broiled beans and pressure cooked beans, suggestive of optimized cooking methods for increasing nutritional and functional contents in cooked food.

악성 기관지호흡기루와 기관지흉강루에 대한 인터벤션 치료

신지훈,김경래,김진형,송호영,Shin, Ji-Hoon,Kim, Kyung-Rae,Kim, Jin-Hyoung,Song, Ho-Young 대한기관식도과학회 2008 大韓氣管食道科學會誌 Vol.14 No.1

Malignant esophagorespiratory fistula is a devastating and life-threatening complication of esophageal and bronchogenic carcinomas. As a non-surgical treatment, peroral stent placement into the esophagus or airway can close-off the fistula and prevent progression of the pneumonia. Although reopening of the fistula is not uncommon despite stent placement, interventional treatment is effective for sealing off reopened ERFs. Bronchopleural fistula is a well-recognized complication of pneumonectomy. There have been several reports to occlude the fistula with use of stents and much more experience is required.

자연경관에 도입되는 건축물의 경관민감도 측정에 관한 연구

신지훈,최원빈,신민지,Shin, Ji-Hoon,Choi, Won-Bin,Shin, Min-Ji 한국농촌계획학회 2018 농촌계획 Vol.24 No.2

As high-rise buildings came in, the landscape of rural areas and natural landscapes often got damaged. Therefore, this study aims to prevent this, grasp the extent of the influence of the surrounding landscape, to grasp the range of height that can be permitted and present the direction of landscape management of agriculture and natural landscape. This study tried to grasp the range of height by using price sensitivity analysis method for two apartment and apartment complex which entered DangJin city and SeoSan city. First, in the case of a two apartment, the range of the height allowable section was from the 6th floor to the 11th floor in close range view, and it was a section from the 7th floor to the 12th floor in medium range view. In the case of the apartment complex, the range of the height allowable range was from the 10th floor to the 17th floor in close range view, the 9th floor to the 16th floor in medium range view. The stress index was found to be positive in a two apartment in close range view, and in the apartment complex case. therefore it was better to set it to a lower in the Range of Acceptable Height(RAH). Second, it showed no difference in the sensitivity of landscape to gender. Thirdly, the results of the landscape sensitivity analysis of major and non-major showed the difference in the medium range view picture of the apartment complex. Majors are lower than the point of minimum height(PMinH) than non-Majors. In the case of major, the stress index was 1.4. it turned out that it was better to make a decision closer to point of minimum height (PMinH). In the case of non-major, the stress index was -1.3. it was also able to accept decision close to the point of maximum height (PMaxH). Since the results of the above research gave changes only in the variable of the height of the landscape, we can not grasp the point of interaction with other variables, and future research is considered necessary.

SWOT 분석을 통한 환경보건 연구의 동향과 전망 고찰

신지훈,나진성,김기태,이종대,양원호,Shin, Jihun,Ra, Jin-Sung,Kim, Ki-Tae,Lee, Jongdae,Yang, Wonho 한국환경보건학회 2022 한국환경보건학회지 Vol.48 No.5

Background: Research in environmental health (EH) is of crucial strategic importance for contemporary society. It is becoming even more critical in light of the increasingly rapid pace of environmental changes, opportunities, and threats. Objectives: This study aimed to identify trends and the prospective of environmental health research using SWOT analysis. Methods: The trends in environmental health research were reviewed in previous studies and reports. Reviewed manuscripts were searched for using the keywords of 'environmental health' and 'environmental hygiene' in the KCI (Korean Journal of Citation Index), KISS (Korean Academic Information), PubMed, and Google Scholar. Results: It is essential to center the EH research agenda around key priorities focusing on technological innovation, job creation, and the increasingly prominent role of the private sector. Given the rapidly evolving global sustainability agenda, greater clarity on the ever-increasing sources of complexity and growing expectations of the public might be needed. This requires the identification of criteria to identify EH research priorities with the ultimate goal of maximizing societal benefit. Public health relevance, such as extent and severity of health impact, level of exposure, and inequalities of effects, could be included. Conclusions: Considering the recent interest in and importance of environmental health, a comprehensive approach to environmental health research should be required through the application of the latest science and technology, citizen participation, and environmental health surveillance systems.

Immune-triggering effect of the foodborne parasite Kudoa septempunctata through the C-type lectin Mincle in HT29 cells

신지훈,Jung-Pyo Yang,Seung-Hwan Seo,Sang-Gyun Kim,Eun-Min Kim,Do-Won Ham,Eun-Hee Shin 생화학분자생물학회 2020 BMB Reports Vol.53 No.9

Kudoa septempunctata is a myxozoan parasite that causes food poisoning in individuals consuming olive flounder. The present study aimed to investigate the currently insufficiently elucidated early molecular mechanisms of inflammatory responses in the intestine owing to parasite ingestion. After Kudoa spores were isolated from olive flounder, HT29 cells were exposed to spores identified to be alive using SYTO-9 and propidium iodide staining or to antigens of Kudoa spores (KsAg). IL-1, IL-8, TNF- and NFKB1 expression and NF-B activation were assessed using real-time PCR, cytokine array and western blotting. The immunofluorescence of FITC-conjugated lectins, results of ligand binding assays using Mincle-Fc and IgG-Fc, CLEC4E expressions in response to KsAg stimulation, and Mincle-dependent NF-B activation were assessed to clarify the early immunetriggering mechanism. Inflammatory cytokines (IL-1, GM-CSF and TNF-), chemokines (IL-8, CCL2, CCL5 and CXCL1) and NF-B activation (pNF-B/NF-B) in HT29 cells increased following stimulation by KsAg. The immunofluorescence results of spores and lectins (concanavalin A and wheat germ agglutinin) suggested the importance of Mincle in molecular recognition between Kudoa spores and intestinal cells. Practically, data for Mincle-Fc and KsAg binding affinity, CLEC4E mRNA expression, Mincle immunofluorescence staining and hMincledependent NF-B activation demonstrated the involvement of Mincle in the early immune-triggering mechanism. The present study newly elucidated that the molecular recognition and immune- triggering mechanism of K. septempunctata are associated with Mincle on human intestinal epithelial cells.

국소환경 모델을 이용한 초미세먼지(PM2.5) 노출 기여율 평가

신지훈(Jihun Shin),최영태(Yongtae Choe),김동준(Dongjun Kim),민기홍(Gihong Min),우재민(Jaemin Woo),김동준(Dongjun Kim),신정현(Junghyun Shin),조만수(Mansu Cho),성경화(Kyeonghwa Sung),이종대(Jongdae Lee),양원호(Wonho Yang) 한국환경보건학회 2022 한국환경보건학회지 Vol.48 No.2

Background: Since people move through microenvironments rather than staying in one place, they may be exposed to both indoor and outdoor PM2.5 concentrations. Objectives: The aim of this study was to assess the exposure level of each sub-population group and evaluate the contribution rate of the major microenvironments. Methods: Exposure scenarios for sub-population groups were constructed on the basis of a 2019 Time-Use survey and the previous literature. A total of five population groups were classified and researchers wearing MicroPEM simulated monitoring PM2.5 exposure concentrations in real-time over three days. The exposure contribution for each microenvironment were evaluated by multiplying the inhalation rate and the PM2.5 exposure concentration levels. Results: Mean PM2.5 concentrations were 33.0 µg/m3 and 22.5 µg/m3 in Guro-gu and Wonju, respectively. When the exposure was calculated considering each inhalation rate and concentration, the home showed the highest exposure contribution rate for PM2.5. As for preschool children, it was 90.8% in Guro-gu, 94.1% in Wonju. For students it was 65.3% and 67.3%. For housewives it was 98.2% and 95.8%, and 59.5% and 91.7% for office workers. Both regions had higher exposure to PM2.5 among the elderly compared to other populations, and their PM2.5 exposure contribution rates were 98.3% and 94.1% at home for Guro-gu and Wonju, respectively. Conclusions: The exposure contribution rate could be dependent on time spent in microenvironments. Notably, the contribution rate of exposure to PM2.5 at home was the highest because most people spend the longest time at home. Therefore, microenvironments such as home with a higher contribution rate of exposure to PM2.5 could be managed to upgrade public health.

Correctness by Construction 을 적용한 안전필수 시스템 개발

신지훈(Jeehoon Shin),오준석(Joon-Seok Oh),윤용기(Yong-Ki Yoon),최진영(Jin-Young Choi) 한국정보과학회 2009 한국정보과학회 학술발표논문집 Vol.36 No.2B

오늘날 많은 안전 필수 시스템들의 오류로 인해 큰 피해들이 발생하고 있다. 이러한 안전 필수 시스템은 높은 무결성과 정확성이 보장되어야 한다. 이러한 속성들을 만족시키기 위해 많은 개발 프로세스들이 연구되고 있으며 이들 중 Praxis의 Correctness by Construction 개발방법이 부각되고 있다. 본 연구에서는 안전 필수 시스템인 열차제어시스템 구성요소들 중 열차간의 간격제어기능을 수행하는 DCM(Distance Constrol Module)을 대상으로 Correctness by Construction을 적용하여 개발한다. 이 연구결과를 토대로 안전 필수 시스템 개발에 있어 가이드라인을 제시한다.

스마트기기 사용에 따른 소방관의 감정노동 통계분석

신지훈(Ji-Hun Shin),박부연(Bu-Yeon Park),이재홍(Jae-Hong Lee),송설경(Sul-Kung Song) 한국전자통신학회 2015 한국전자통신학회 논문지 Vol.10 No.11

스마트 기기를 활용한 다매체 119신고서비스의 도입으로 소방관들은 감정노동에 더욱 노출되게 되었다. 본연구는 이러한 소방관의 높아진 감정노동 수준이 직무만족에 미치는 영향을 알아보기 위하여 수행되었다. 그결과 소방관의 감정노동수준이 높을수록 직무 스트레스(β=0.166, p=0.000)와 사회적 지지(β=0.540, p=0.000) 정도는 높아지는 결과를 보였으나, 직무만족은 낮아지는 경향을 보였다(β=-0.136, p=0.000). 소방관들은 국민의 안전과 재산을 보호하는 중요한 업무를 수행하므로 이들의 직무만족 정도는 업무수행의 원동력이 된다. 이에 소방관의 감정노동을 관리할 수 있는 체계적이고 실질적인 예방 교육과정이 필요하리라 생각된다. The introduction of multimedia 119-notification service utilizing smart devices causes firefighters to be more exposed to emotional labor. The purpose of this study is to investigate the effect of increased emotional labor of firemen on job satisfaction. As a result, the higher the emotional labor of firefighters is, the higher job stress ( β=0.166, p=0.000) and social support(β=0.540, p=0.000) are. But job satisfaction tends to be lower(β=-0.136, p=0.000). As they play an important role to protect the safety and property of citizens. their job satisfaction becomes the driving force of their duty. Therefore, we think that some systematic and substantial prevention curriculum to manage their emotional labor is required.

GPR 분석을 위한 자갈궤도 자갈의 감쇄특성을 이용한 이득함수 개발

신지훈(Jihoon Shin),최영태(Yeongtae Choi),장승엽(SeungYup Jang) 한국지반환경공학회 2017 한국지반환경공학회논문집 Vol.18 No.4

자갈궤도는 100여년 이상 전세계적으로 널리 사용되는 궤도구조로 저렴한 초기 건설비용, 유연한 유지보수와 진동 및 소음의 저감효과가 있지만, 열차운행에 따라서 지속적인 침하가 발생하는 단점이 있다. 이로 인해 지속적인 유지보수가 필요하며, 최근 열차의 속도, 용량, 중량의 증가로 유지보수비용이 증가하고 있는 실정이다. 파울링(fouling)은 노반 세립분이나 자갈입자가 파쇄되면서 발생한 세립분이 자갈 사이의 공극을 메우는 현상으로 배수가 나빠지고, 자갈궤도의 침하를 가속화시키는 등 자갈도상의 열화의 주원인으로 지목되고 있다. 본 논문에서는 GPR(Ground Penetrating Radar)을 이용하여, 도상의 상태를 평가 할 수 있는 분석방법을 제안하였다. 경험에 의존하는 기존의 분석기법을 대신하여, 고속선에 사용되는 자갈의 감쇠 특성을 반영한 이득함수(gain function)를 제안하였다. 실내 박스 실험과 실모형 실험을 통해 제안한 이득함수로 증폭한 GPR신호에 힐버트 변환을 추가로 적용하여 자갈층과 노반층에서 반사된 신호의 세기변화를 깊이에 따라 계산하였다. 이로부터 신호의 세기가 비교적 크게 변화하는 곳을 파울링층과 노반층의 경계로 구분할 수 있었다. 다만 현장적용을 위해서는 침목의 영향을 분리하고 전자기파 분산특성 등에 대한 추가 연구가 필요할 것으로 사료된다. Ballasted track has been used as track system for more than 100 years. Ballasted track has advantages of low construction cost, flexible maintenance, low noise and vibration, and so on. However, ballasted track leads to continuous settlement which causes maintenance. Recently, increase in speed, traffic volume, and weight of train requires more frequent maintenance. Fouling, well-known phenomenon of accumulation of fine materials due to intrusion of subgrade and breakage of ballast materials, expedites the settlement (i.e., irregular settlement) of track. Ground Penetrating Radar (GPR) can be one of non-destructive tools that can evaluate fouling level of ballast. In this paper, a gain function based on the attenuation characteristics of ballast material is suggested in conjunction with Hilbert transform. Lab box tests and full-scale tests indicate that the suggested method reasonably classifies clean, fouled layers, and subgrade. However, additional study to eliminate effect of sleeper and to include the scattering features of the electromagnetic wave in ballast voids should be required in order to enhance the accuracy.

생태적 보전가치 평가를 통한 자연공원 계획에 관한 연구 -황매산 군립공원을 중심으로-

신지훈 ( Ji Hoon Shin ) 한국환경보건기술학회(구 한국환경복원녹화기술학회) 2010 한국환경복원기술학회지 Vol.13 No.5

This study is intend to evaluate natural conservation value, and to suggest natural park plan based on conservation value evaluation. In this study evaluation items are selected through related studies about ecological conservation evaluation, and evaluation items in this study can be classified into 2 aspects, ecological environment and topographic environment. After each evaluation items are overlaid with GIS program, management levels are derived from comprehensive overlaid maps of each evaluation items. Management areas can be classified into 5 levels; Critical Conservation Area, Conservation Area, Restoration Area, Passive Usable Area, Active Development Area and Settlement Area. So management areas can be matched each management levels to land use of natural park, that is district of preservation, district of natural environment, district of settlements and district of mass facilities. This study have good enough to evaluate ecological value for natural park plan, but, it is difficult to evaluate conservation value only with maps of each evaluation items, so it needs supplementary field survey for precise conservation value evaluation.