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토끼 태아에서 표피성장인자 투여가 코티졸 , 티록신 , 프로락틴의 생성에 미치는 영향
김수평(Soo Pyung Kim),신종철(Jong Chul Shin),이종건(Jong Kun Lee),김용욱(Yong Wook Kim),변태섭(Tae Sup Byun),신재인(Jae In Shin),이종승(Chong Seong Yi),나종구(Jong Gu Rha) 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.12
N/A Respiratory distress syndrome (RDS) is a major cause of death in premature neonates, and it is caused by the failure of morphological and biochemical lung maturation (synthesis and secretion of lung surfactant). It is known that cortisol, thyroxine, prolactin, epidermal growth factor (EGF), and estrogen accelerate the lung maturation. Cortisol and thyroxine are currently used in the antenatal treatment for the prevention of RDS in premature neonates. In order to evaluate the effect of EGF on the levels of cortsol, thyroxine, and prolactin, this study was undertaken. Phosphate buffered saline (PBS) with and without EGF was directly injected into the 25 days gestational fetus in uterus. Blood was collected for the measurement of cortisol, thyroxine, and prolactin one day or two days after the injection. Body weights and lung weights were also measured. The results were as follows: 1. There was no significant difference in body weights and lung weights between PBS-treated group(control group) and EGF-treated poup(experimental group), 24 hours and 48 hours after the injection. 2. 24 hours after the injection, the levels of cortisol were significantly inaeased in the EGF-treated group compared with those in the PBS-treated group. However 48 hours after the injection, there was no significant difference in the levels of cortisol between the two groups. The levels of thyroxine and prolactin in the EGF-treated group did not significantly differ from those in the PBS-treated group 24 hours and 48 hours after the injection. In conclusion, in vivo, the synthesis of cortisol may be affected by EGF treatment, which suggests that the action of EGF for lung maturation may be partially mediated by the increased endogenous levels of cortisol.
신재인 ( Shin Jae-in ),박창호 ( Park Chang-ho ),이병주 ( Lee Byeong-ju ) 한국구조물진단유지관리공학회 2005 한국구조물진단유지관리공학회 학술발표대회 논문집 Vol.9 No.1
Many highway structures become functionally obsolete due to inadequate width before they become structurally deficient. Because widening is almost always more economical than complete replacement, there is a need to make available the results of research and field experience pertaining to the widening of structures. For this reasons, in Korea many widening structures constructed. In the widening highway sites, widening for keeping of existing road height and improving of road eight is widely adopted. At times, new structures was constructed m using fill over top of design level but existing structures was constructed no study of increased fill over top. In this paper, load reduction method for subway structure is proposed and failure example of the four sided box culvert is illustrated. Therefore design method for construction between the new and old structure in widening highway box culvert provides the designer and constructor.
『요루노네자메(夜の寝覚)』의 여주인공 조형 ―생령사건의 의미를 중심으로―
신재인 ( Shin Jae-in ) 한국일어일문학회 2023 日語日文學硏究 Vol.124 No.0
本稿は、平安後期物語『夜の寝覚』の女主人公の造形と生霊事件の関係について考察したものである。『源氏物語』の六条御息所は、自分が光源氏の正妻葵の上の病床に生霊になって現れたという噂を聞いて、葵の上とみられる女性を苦しめる夢を見る。思い詰めた御息所は出家したものの、死後にも死霊になって源氏の女たちを苦しめた。『夜の寝覚』の中の君は自分の生霊が現れたという噂を聞くにつけ、出家を志したが、妊娠によって出家できなかった。彼女は和泉式部の法華経を引く歌を読みながら宿世を嘆いた。同じく生霊といわれた二人の女性の行く末は、出家と非出家に分かれて、物語の展開に影響した。中の君は現存本以後の末尾欠陥部分において、偽死事件の後、子供たちのために再び生きていくことで『無名草子』に批判された。彼女は、所詮一夫多妻制の下で『蜻蛉日記』の道綱母や和泉式部の絶望を引き継ぎつつ、生きていくことを余儀なくされた一人の女性であった。生霊事件の汚名はそういう中の君の自画像と深くかかわっているものであった。物語の行く末に影響した『夜の寝覚』の生霊事件を『源氏物語』の六条御息所の生霊と読み比べることにより、『夜の寝覚』の女主人公の造形を平安の物語史における一人の女性像として読み直すことができる。 This paper aims to analyze the character of Yoru no Nezame´s heroine with ‘living ghost incident’. The Lady Rokujo of The Tale of Genji hears a rumor that she appeared as a living ghost on the sick bed of Lady Aoi, the lawful wife of Hikaru Genji, and dreams of tormenting a woman who is believed to be Lady Aoi. After suffering, Lady Rokujo became a bonze, but she became a ghost and tormented the women of Hikaru Genji. Naka no Kimi, the heroine of Yoru no Nezame, wanted to become a bonze upon hearing a rumor that her living ghost had tormented Lady Ichinomiya, but was unable to. She lamented her destiny by composing a song that quoted the Lotus Sutra by Izumi Shikibu. The fates of the two women, who are also said to have appeared as a living ghost, were divided into those who became a bonze and those who did not, and influenced the stream of the story. Naka no Kimi was criticized by Mumyo Zoshi for faking her death and coming back to life for her children in the defective part of the story. She was, after all, a woman who was forced to live under the polygamy system, inheriting the despair of Izumi Shikibu and Michitsuna´s Mother in Dragonfly Diary. The stigma of the ‘living ghost incident’ was deeply related to Naka no Kimi´s self-portrait. By comparing ‘living ghost incident’ in Yoru no Nezame with that of Lady Rokujo in The Tale of Genji, I can reinterpret the female character in Yoru no Nezame as a female figure in the history of Heian Monogatari.