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병리조직학적(病理組織學的)으로 확진(確診)된 각종 위질환(胃疾患)에 있어서 위내시경진단법(胃內視鏡診斷法)과 위(胃) X 선진단법에 의한 소견의 비교 검토
송인성 대한소화기학회 1979 대한소화기학회지 Vol.11 No.2
Preoperative gastroendoscopic and roentgenologic findings of stomach were evaluated in 231 cases of gastric diseases proven by the surgical intervention and histopathological examination. The results were as follows: 1) In the diagnosis of 175 cases of gastric cancer, correct diagnosis was made by gastroendoscopy in 82.3% and by rcentgenography in 81.6% significantly different statistically. And gastroendoscopy plus roentgenography permitted a correct diagnosis in 90% of the cases. The rate by which both gastroendoscopy and roentgenography for the diagnosis of gastric cander made diagnosis concomitantly was 78.6% in correctly diagnosed group and 8% in incorrectly diagnosed group, summing up the coincidence rate between two methods to 86.6%. 2) In the diagnosis of 31 cases of benign gastric ulcer, correct diagnosis was made by gastroendoscopy in 48.4% and by roentgenography in 67.7%, significantly different statistically. And gastroendoscopy plus roentgenography permitted a correct diagnosis in 74.2%. The rate of identical diagnosis by both gastroendoscopy and roentgenography for the diagnosis of benign gastric ulcer, on the contrary to gastric cancer, was 48.4% in correctly diagnosed group and 22.6% in incorrectly diagnosed group, making the coincidence rate of diagnosis by two methods in 71%. It is claimed at correct diagnosis for the brnign gastric ulcer from the above data that some other diagnositic methods like gastric output study and cytology of gastric juice are needed beyond the conventional gastroendoscopic and radiologic method, as with needs of expertise in both fields.
송인성(Insung Song),정영만(Youngman Jung),김용석(Yongseok Kim),이창돈(Changdon Lee),양순용(Soonyoung Yang) 한국자동차공학회 2009 한국자동차공학회 학술대회 및 전시회 Vol.2009 No.11
This paper presents the development of a cleaner for curbstone cleaning purpose. The cleaner sprays high pressure water jet and cleans the curbstone repeatedly along the section. The structure of the cleaner is divided into two sections: water supply vehicle section and the section for curbstone cleaner. The cleaner has two DC motors and can move forward, backward, left and right side. The cleaning device is composed of nozzles to spray high pressure water jet onto curbstone. In this study, the 3D modeling of the cleaner is made using CAD software and the prototype is also made for the selection of optimum nozzle shape and size.
Empirical Investigation on the Determinents of Retail Prices
송인성 서울대학교 경영연구소 2011 Seoul Journal of Business Vol.17 No.1
This study utilizes a rich data set from multiple retail chains to investigate the determinants of retail prices identified from marketing literature:wholesale price, retail competition, time elapsed since last promotion. The empirical results indicate that although all three factors are statistically significant in explaining the observed retail prices, they differ in the extent to which they explain retail price variation. The competing retail prices appear to explain more of variations in retail prices than other factors do. It is also found that a substantial variation in the pass-through of a brand exists across retailers. I also find positive cross-retail price responses, i.e.,price reductions in competing retailers tend to lower the prices in a retailer. Regarding the impact of time since last promotion, the result supports the concavity of the effect of the variable. In terms of the direction, the overall effect of TLP is positive initially and then decays.
송인성,이성률,정유정,정승훈,허혜진,김형규,고태희,고경수,김나리,이병두,염재범,한진 생화학분자생물학회 2013 Experimental and molecular medicine Vol.45 No.10
Bortezomib is a proteasome inhibitor used for the treatment of relapsed/refractory multiple myeloma (MM). However, intrinsic and acquired resistance to bortezomib has already been observed in MM patients. In a previous report, we demonstrated that changes in the expression of mitochondrial genes lead to changes in mitochondrial activity and bortezomib susceptibility or resistance, and their combined effects contribute to the differential sensitivity or resistance of MM cells to bortezomib. Here we report that the combination treatment of bortezomib and 2-methoxyestradiol (2ME), a natural estrogen metabolite, induces mitochondria-mediated apoptotic cell death of bortezomib-resistant MM KMS20 cells via mitochondrial reactive oxygen species (ROS) overproduction. Bortezomib plus 2ME treatment induces a higher level of cell death compared with treatment with bortezomib alone and increases mitochondrial ROS and Ca2þ levels in KMS20 cells. Pretreatment with the antioxidant N-acetyl-L-cysteine scavenges mitochondrial ROS and decreases cell death after treatment with bortezomib plus 2ME in KMS20cells. Moreover, we observed that treatment with bortezomib plus 2ME maintains the activation of c-Jun N-terminal kinase (JNK) and mitogen-activated protein kinase kinase kinase 4/7 (MKK4/7). Collectively, combination treatment with bortezomib and 2ME induces cell death via JNK-MKK4/7 activation by overproduction of mitochondrial ROS. Therefore, combination therapy with specific mitochondrial-targeting drugs may prove useful to the development of novel strategies for the treatment of bortezomib-resistant MM patients.
송인성 한국마케팅관리학회 2015 마케팅관리연구 Vol.20 No.1
This study provides a very brief overview of structural dynamic models in marketing. Structural dynamic models here refer to the models that incorporate forward-looking behaviors in which decision makers take into account the future states when making decisions. A brief introduction on the typical forms of dynamic programming model is presented. A few representative studies in the literature in the single-agent dynamics and also in the multi-agent dynamics are reviewed. And then, a few recent methodological advancements to relieve computational burdens of dynamic programming models are discussed. 이 연구에서는 마케팅 분야의 구조적 동태 모형의 실증 문헌들을 간략하게 살펴보았다. 구조적 동태 모형이라 함은 의사 결정자가 자신의 효익을 극대화하는 최적의 의사 결정을 하는데 있어 미래의 상태를 예견하고 이를 현재 시점의 의사 결정에 반영하는 선견적 행동을 한다는 가정하에 그러한 선견적 행동을 수리적인 실증 모형으로 표현한 것이다. 선견적 행동을 직접 모형화한 동적 계획법 모형의 일반 형태를 간략하게 서술하고, 모형의 특성을 단일 의사 결정자 모형과 복수 의사 결정자 모형으로 구분하여 구조적 동태 모형이 사용된 마케팅 분야의 대표적인 연구들을 살펴보았다. 또한 구조적 동적 모형 사용에 있어 계산상의 부담이 큰 장벽인데 이를 해결하고자 제시된 최근의 의미있는 진전들을 몇 가지 짚어보았다.