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송유선,송화순,이범훈,김혜림,Song, Yu-Sun,Song, Wha-Soon,Lee, Bum-Hoon,Kim, Hye-rim 한국섬유공학회 2008 한국섬유공학회지 Vol.45 No.4
An enzymatic treatment method was introduced using pectinase to scouring cotton fiber from a cotton/chitosan-blend fabric without damaging the chitosan component. The pectinase treatment conditions such as the pH, temperature, enzyme concentration, and treatment time were optimized by measuring the weight loss and the degree of reduction of the galacturonic acid in the cotton fabric. The changes in the weight loss, tensile strength, moisture regain, dyeability, pill formation, and surface morphology of the cotton/chitosan blend with the changes in the pectinase treatment conditions were evaluated. The optimum pectinase treatment conditions for cotton fabric were found to be a treatment temperature of $55^{\circ}C$, a treatment time of 50 minutes, a pectinase concentration of 0.5% (owf), and a pH of 8.0. The pectinase treatment of the cotton/chitosan blend improved the fabric's moisture regain, dyeability, and resistance to pill formation due to the removal of the non-cellulose cotton, but did not affect the chitosan's weight loss, relative viscosity, and degree of deacetylation. The results showed that pectinase treatment of cotton/chitosan blends is an effective method of removing non-cellulose cotton without damaging chitosan.
사람 호흡기 상피세포에서 Protopanaxadiol의 Lipopolysaccharide로 유도된 활성산소 생성과 MUC5AC 과발현 억제 효과
송유선,김준희,나형균,최윤석,송시연,김용대,배창훈 대한이비인후과학회 2019 대한이비인후과학회지 두경부외과학 Vol.62 No.9
Background and Objectives MUC5AC is one of the major secretory mucin genes in thehuman airway epithelium. MUC5AC expression is increased by a variety of inflammatory mediators. Protopanaxadiol (PPD), one of the major active metabolites in ginseng, is known to haveanti-inflammatory, antitumor and antioxidant properties. However, the effects of PPD on mucinsecretion of airway epithelial cells still have not been reported. Therefore, the aim of this studyis to investigate the effect of PPD on lipopolysaccharide (LPS)-induced MUC5AC expressionin human airway epithelial cells. Materials and Method In the mucin-producing human NCI-H292 airway epithelial cells,the effect of PPD on MUC5AC expression was investigated using reverse transcription-polymerasechain reaction and enzyme immunoassay after treated with LPS. N-acetylcysteine (NAC)as a reactive oxygen species (ROS) scavenger, and apocynin as a nicotinamide adenine dinucleotidephosphate oxidase inhibitor were used to compare the inhibitory effect of PPD on LPSinducedROS production in human NCI-H292 cells. Results LPS significantly increased MUC5AC mRNA expression and protein production. LPS also increased ROS production. PPD inhibited LPS-induced MUC5AC mRNA expressionand protein production as well as ROS production. In addition, NAC and apocynin inhibitedLPS-induced MUC5AC mRNA expression and protein production. Conclusion These results demonstrate that PPD inhibits LPS-induced MUC5AC expressionvia ROS in human airway epithelial cells and the inhibitory effect of PPD was similar to that ofNAC and apocynin. These findings indicate that PPD may be a therapeutic agent for control ofmucus secretion and oxidative stress in human airway epithelial cells.
송유선,이인숙,최경운,조길호,이성문,이영환,김정일 대한자기공명의과학회 2014 Investigative Magnetic Resonance Imaging Vol.18 No.4
Objective: The aims of this article are to differentiate soft tissue masses showing low signal intensity on T2-weightedimages (T2WIs) according to the histopathologic findings. Conclusion: To know relatively small numbered soft tissue masses with low signal intensities on T2WIs adding characteristiclocation, morphology, signal intensities on other sequences might be helpful for differential diagnosis of mostly nonspecificsoft tissue tumors on MRI.
기관지확장증이 있는 16세 여자 환자의 비결핵 항산균 폐질환
송유선,정혜인,이보라,허희재,고원중,김지현,안강모,경예찬 대한 소아알레르기 호흡기학회 2020 Allergy Asthma & Respiratory Disease Vol.8 No.4
Nontuberculous mycobacterial (NTM) pulmonary disease generally occurs in old people with underlying lung disease. However, unlike adults, NTM infections in children with normal immunity are rare, and they occasionally manifest as lymphadenitis. We herein present a rare case of NTM pulmonary disease in a girl who is the youngest patient reported in Korea. A 16-year-old female was brought to the hospital because of dyspnea on exertion, fever, and productive cough. The patient had bronchiectasis. She underwent Fontan operation for right isomerism, double outlet right ventricle, pulmonary stenosis, and had been taking prophylactic antibiotics for asplenia. NTM were found in the sputum and bronchoalveolar lavage fluid by acid fast bacillus (AFB) staining and culture, which were identified as Mycobacterium avium. The treatment started with azithromycin, ethambutol and rifampicin. After 6 months of treatment, respiratory symptoms improved and the sputum AFB culture became negative. She is currently on medication with above-mentioned drugs for 10 months without any adverse effects. This case suggests that NTM pulmonary disease should be suspected and properly treated especially in children and adolescents with underlying lung disease.
연구논문 : 호료와 매염제가 황벽추출물로 날염한 면/견직물의 날염성질에 미치는 영향
송유선 ( Yu Sun Song ),송화순 ( Wha Soon Song ) 한국의류산업학회 2013 한국의류산업학회지 Vol.15 No.5
In this study, the dyeing properties of Phellodendron amurense on cotton and silk fabrics were evaluated to establish a scientific database of dyeing methods using natural dyes with the ultimate aim of facilitating the practical use of these dyes. The optimal thickener and dyeing concentrations depending on the thickener type were identified when dyeing with P. amurense, and the fabric color, color fastness, and antibiosis were examined for various thickeners, fabrics, and mordants. The results were as follows.: The optimal concentrations of thickeners when dyeing on cotton and silk fabrics were CMC 3% (w/w), Mayprogum 7% (w/w), and Indalka 9% (w/w). The optimal concentration of P. amurense was 25% (w/w), irrespective of the type of thickener. To maintain the hue unique to P. amurense, thickening with Mayprogum or Indalka and mordanting with Al was effective for cotton, while thickening with Mayprogum or Indalka and mordanting with Al or thickening with CMC and mordanting with gallnut was effective for silk. The dry-cleaning fastness and abrasion resistance of cotton fabrics dyed with P. amurense were excellent at the 4-5 level. Gallnut was effective for washing fastness and perspiration fastness against color degradation, and FFC was effective for light fastness. The washing fastness, dry-cleaning fastness, abrasion resistance, and perspiration fastness of silk fabrics dyed with P. amurense were excellent at level 4, except for washing and perspiration fastness, and FFC was effective for the improvement of light fastness. Dyeing cotton and silk fabrics with P. amurense thus yielded antibiosis and excellent washing fastness.