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      • KCI등재

        유리체절제술 중 발생한 발살바현상 관련 맥락막상강출혈

        임한웅,고병우,송유미,이병로,Han Woong Lim,Byung Woo Ko,Yumi Song,Byung Ro Lee 대한안과학회 2008 대한안과학회지 Vol.49 No.6

        Purpose: To report a suprachoroidal hemorrhage by Valsalva maneuver during vitrectomy under general anesthesia. Case summary: A healthy 26-year-old man had vitrectomy under general anesthesia due to rhegmatogenous retinal detachment in his right eye. During scleral indentation and endolaser photocoagulation, he took a sudden and severe bucking reflex because the effect of general anesthesia was insufficient. After the bucking reflex, suprachoroidal hemorrhage occurred in his right eye. Immediate IOP elevation and hyperfluorocarbon tamponade was performed to remove the suprachoroidal hemorrhage and reattach the retina and choroid. The patient’s corrected visual acuity was 20/50 and slender crescent‐shaped choroidal rupture remained around the temporal area of the macula, unlike traumatic choroidal rupture. Following fluorescein angiography, staining was evident at the choroidal rupture site; no fluorescein leakage was evident. Conclusions: We report a case of acute suprachoroidal hemorrhage which we investigated by fundus examination and fluorescein angiography. J Korean Ophthalmol Soc 49(6):1022-1027, 2008

      • KCI등재

        여러 가지 트리암시놀론제재의 유리체강내 투명기름방울모양 잔존물 발생 양상의 비교

        임한웅,고병우,송유미,박영숙,이병로,Han Woong Lim,M,D,Byung Woo Ko,M,D,Yumi Song,M,D,Young Sook Park,M,D,Byung Ro Lee,M,D 대한안과학회 2008 대한안과학회지 Vol.49 No.7

        Purpose: To investigate the characteristics of the clear oil-drop residue observed in the vitreous cavity after intravitreal injection of different brands of triamcinolone acetonide (TA), and to compare this ingredient’s effects in those products. Methods: Intravitreal injections of four different brands of triamcinolone acetonide (4 mg/0.1 mL), which are commercially available in Korea, were given to 40 eyes for the treatment of macular edema due to a variety of causes from October 2005 through February 2006. Regular slit-lamp biomicroscopy of fundus had been performed periodically with digital image acquisition equipment after injection of TA for at least two months. We analyzed the characteristics of this residue and compared the number and size of this residue in each product. Results: Four TA products commercially available in Korea were used, with vehicles composed of preservatives and suspending agents. There were differences between products in respect to ingredients and content, as well as the characteristics of the intravitreal clear oil droplet-like residue. Conclusions: Each TA product has a variable frequency and variable amounts of clear oil droplet-like residue, which seems to be a component of the vehicle. This variation could generate differences in efficacy, side effects, and retaining duration. It should be verified whether commercial TA products are consistently safe and effective. J Korean Ophthalmol Soc 49(7):1087-1093, 2008

      • KCI등재

        백내장수술 전 구후마취 직후 발생한 망막중심동맥과 중심정맥의 폐쇄 1예

        임한웅,고병우,송유미,박영숙,이병로,Han Woong Lim,M,D,Byung Woo Ko,M,D,Yumi Song,M,D,Young Sook Park,M,D,Byung Ro Lee,M,D 대한안과학회 2008 대한안과학회지 Vol.49 No.6

        Purpose: To report central retinal vein and artery occlusion after retrobulbar anesthesia for a cataract operation. Case summary: A 65-year-old woman was transferred to our facility 4 days after she had undergone cataract extraction with IOL implantation. She could count fingers and had a relative afferent papillary defect in her left eye. As seen upon fundus examination, dot-shaped, circular-shaped irregular, and partially linear-shaped retinal hemorrhages were evident. Fluorescein angiography revealed that branch arteries around the nasal and temporal areas were not filled, and that the filling of veins was delayed. After two weeks, the patient was only able to recognize hand motion, and her intraocular pressure was 10 mmHg. According to a fundus examination, the size and quantity of retinal hemorrhages increased, and a pale, macular edema was observed. Following fluorescein angiography, the filling defect of branch vessels on the nasal and temporal areas was still evident, and the blocked fluorescence of capillaries on the fundus was prominent. After two months, she could still only recognize hand motion, and her intraocular pressure had increased to 35 mmHg; we therefore diagnosed a neovascular glaucoma. Conclusions: A patient experienced a serious central retinal vessel occlusion after retrobulbar anesthesia for cataract extraction. Retrobulbar injections should therefore be administered with great caution to prevent this outcome. J Korean Ophthalmol Soc 49(6):1013-1017, 2008

      • KCI등재

        황반질환에 따른 스펙트럼 영역 빛간섭단층촬영의 다양한 오류 분석

        신용운,이주향,전재연,송유미,조희윤,이병로,Yong Woon Shin,Ju Hyang Lee,Jae Yeon Jun,Yumi Song,Hee Yoon Cho,Byung Ro Lee 대한안과학회 2010 대한안과학회지 Vol.51 No.8

        Purpose: To report the frequency, severity and various types of artifacts associated with spectral-domain optical coherence tomography (SD-OCT) based on macular pathologies. Methods: Data was collected retrospectively from 116 eyes of 116 subjects. SD-OCT (3D-1000, Topcon Corp., Japan) imaging was performed in 40 healthy eyes, 45 eyes with intraretinal pathology (IRP) and 31 eyes with subretinal pathology (SRP). The scan protocol was 12×6 mm radial scan. The frequency and types of artifacts were investigated in each scan and were analyzed based on macular disease. Additionally, the effect of artifacts on the measurement of macular thickness was studied. Results: Errors occurred in 77 eyes (66.38%). Inner retinal boundary misidentification (IRBM) was the most common error (25.86%), with the frequencies of other types of artifacts being 10.34% for off-center fixation, 15.52% for degraded image and 8.6% for outer retinal boundary misidentification (ORBM). The overall error rate of SD-OCT in the retinal pathology group was much higher than that in the normal group. Macular thickness was underestimated in the IRP group because the outer retinal boundary of the IRP group tended to be misidentified toward the inner retina (p<0.01). Conclusions: SD-OCT can frequently cause various types of artifacts in patients with macular disease. When interpreting OCT images, the artifacts of SD-OCT should be considered in order to obtain accurate macular thickness and to prevent erroneous clinical decisions. J Korean Ophthalmol Soc 2010;51(8):1084-1091

      • KCI등재

        신경항법을 이용한 반복적 경두개자기자극의 적용 위치 선정 방법과 우울증 치료 효과 고찰

        김명주(Myeongju Kim),송유미(Yumi Song),서채원(Chaewon Suh),마지영(Jiyoung Ma),홍가혜(Gahae Hong),김정윤(Jungyoon Kim) 대한생물치료정신의학회 2020 생물치료정신의학 Vol.26 No.2

        Repetitive transcranial magnetic stimulation (rTMS) is widely recognized as an effective and noninvasive neuromodulation for treating depression, and has been applied in a wide range of clinical settings. However, previous studies often reported inconsistent antidepressant effects that may be due to differences in the rTMS protocols such as coil placement. The typical simulation site for rTMS depression protocol is the left dorsolateral prefrontal cortex (DLPFC). Targeting the exact site of the left DLPFC while considering individual brain structure has been challenging due to the non-invasive nature of rTMS. Several researchers have applied various targeting methods to overcome the abovementioned issue. Most of the previous studies have applied the “5-cm rule” or the “international 10-20 system,” which is easily applicable. Recently, researchers started to apply a neuronavigation system that targets the stimulation site based on neuroimaging of each individual. Pros and cons of targeting methods have been discussed in terms of validity and reliability of targeting stimulation sites, differences in treatment responses, as well as considerations of individual characteristics. Therefore, the current review focuses on the targeting methods of stimulation site and the treatment effects of depression in previous studies. For discussion, we divided neuronavigation methods into using fixed coordinates and using individualized targets. Furthermore, the limitations of each targeting method are discussed that may potentially contribute to the development of the optimal rTMS protocol for depression treatment.

      • KCI등재

        월경주기에서의 호르몬의 변화가 뇌에 미치는 영향: 구조 및 기능적 자기공명영상 연구를 중심으로

        하은지(Eunji Ha),송유미(Yumi Song),김정윤(Jungyoon Kim),윤수정(Sujung Yoon) 대한생물치료정신의학회 2021 생물치료정신의학 Vol.27 No.2

        It is well known that sex hormones are potential modulators of brain functions and women experience dynamic hormonal changes during the menstrual cycle. Previous animal studies have reported that the variations in sex hormones over the menstrual cycle may affect cognitive function, emotion, and behavior by altering structures and functional connectivity of the brain. Considering the prevalence of certain neuropsychiatric disorders such as mood and anxiety disorders is relatively high in women, as compared with men, fluctuations of sex hormones over the menstrual cycle may influence the human brain and potentially underlie sex differences in clinical features of several neuropsychiatric disorders. There is, however, little evidence regarding the exact mechanisms underlying the effects of sex hormones on the human brain. In this review, we focused on studies to examine structural and functional changes over the menstrual cycles in women and aimed to provide an up-to-date overview of neuroimaging studies regarding the effects of sex hormonal fluctuations on the brain and behaviors.

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