전동 및 수동 구급 침상을 이용한 119구급활동의 신체역학적 부하 비교 무작위 마네킨 시뮬레이션 연구

송성욱,강명신,강현정,박진형,최명재,홍기정,신상도 대한응급의학회 2019 대한응급의학회지 Vol.30 No.6

Objective: The purpose of this study was to compare the biomedical demands between a manual stretcher cart (Manual Cot) and a novel powered stretcher cart (Power Cot) during simulated routine stretcher handling activities. Methods: A randomized cross-over design mannequin simulation study was planned. Fourteen participants sequentially performed routine stretcher handling tasks, including unloading, lowering, raising, and loading tasks with the Manual Cot and Power Cot. The biomechanical workload of each participant was assessed by measuring the muscle activity of four muscles (bilateral L4/5 erector spinae and rectus femoris) through an 8-channel electromyogram (EMG) measurement system by attaching the surface EMG. The time required to perform each task was measured, and after the end of the simulation, the participants were given a subjective questionnaire consisting of seven items (five-point Likert scale) on the usefulness and usability of the two stretcher carts. Results: Fourteen participants, six males and eight females, performed four routine stretcher handling scenarios. The median total task times for the Manual Cot and Power Cot were similar (95 seconds; range, 49-105 vs. 94 seconds; range, 84-140; P=0.063). For the lowering, raising, and loading tasks, the effects of Power Cot were significantly lower than the normalized muscle voluntary contraction (%) cumulative sum of the back or thigh (P<0.05). Compared to Manual Cot, the use of Power Cot resulted in a decrease in total muscle activity of 18.0-63.5% in the back muscles and 6.7-83.9% in the thigh muscles during the task simulation. The participants preferred the Power Cot in terms of usefulness in subjective perceptions. Conclusion: This simulation study identified that the Power Cot reduced the physical stress of emergency medical services workers without any significant performance time delay when performing stretcher-handling activities.

대하소설과 남녀 애정 문제 - 소설사적 흐름을 중심으로 -

송성욱 성심어문학회 2002 성심어문논집 Vol.24 No.-

조선시대 장편소설과 단편소설의 거리

송성욱 성심어문학회 1999 성심어문논집 Vol.20ㆍ21합병 No.-

응급실을 방문한 급성 폐색전증 환자의 예후 예측에 있어서 전산화 단층촬영 혈관 조영술의 정량적 분석의 유용성에 관한 연구

송성욱,박진식,제환준,이현주,박은아,신상도,정성구,곽영호,서길준 대한응급의학회 2009 大韓應急醫學會誌 Vol.20 No.1

Purpose: We evaluated the usefulness of quantitative analysis of computed tomography (CT) pulmonary angiography as a predictor of the prognosis of acute pulmonary embolism (PTE). Methods: We performed a retrospective analysis of 55 patients who visited our emergency department from January 2000 to November 2007 who were confirmed with PTE by CT pulmonary angiography. Two radiologists blinded to patient outcome measured CT parameters including the diameter of vessels and chambers, and the quantified pulmonary artery (PA) clot load score on the basis of embolus size and location. CT parameters and other clinical predictors were analyzed to determine their ability to predict major adverse event (MAE). Results: Of the 55 patients, 16 (29.1%) had a MAE PTE related shock, intubation, death, thrombolysis, right ventricular (RV) dysfunction within 30 days). Geneva score (odds ratio 2.5, 95% CI 1.18-5.29, p=0.02) and PA clot load score (odds ratio 1.64, 95% CI 1.18-2.27, p<0.01) were strong independent predictors of MAE. The cut-off value of Geneva and PA clot load scores were 4.5 and 19.0, respectively, and the area under the ROC curve were 0.697 (0.546~0.848) and 0.908 (0.828-0.988), respectively. Conclusion: Geneva and PA clot load score are significant predictors of PTE related shock, intubation, death, thrombolysis, and RV dysfunction within 30 days. CT pulmonary angiography is a useful predictor for the prognosis of PTE as well as a useful diagnostic tool.

폐암 환자에서 Cyfra 21-1의 진단적 유용성 평가

송성욱,유은형,조현정 대한진단검사의학회 2015 Laboratory Medicine Online Vol.5 No.3

Background: Lung cancer is the most lethal malignant neoplasm in the world. Serum cytokeratin fragment 21-1 (Cyfra 21-1) is a valuable tumor marker for detection of lung cancer, and it has good sensitivity and specificity. The aim of this study was to investigate the diagnostic value of Cyfra 21-1 levels in patients with lung cancer. Methods: We retrospectively reviewed 814 samples from 169 patients with lung cancer, 124 patients with benign pulmonary diseases, and 521 normal controls from health check-up clinic. Serum Cyfra 21-1 levels were determined with Architect CYFRA 21-1 kit (Abbott, USA) using Architect i2000 analyzer. Results: Median levels and interquartile ranges for Cyfra 21-1 in patients with lung cancer (non-small cell lung cancer: 3.16 [1.98, 9.00] ng/mL, small cell lung cancer: 3.32 [2.07, 5.20] ng/mL) were higher than those in patients with benign pulmonary diseases (1.50 [1.17, 2.17] ng/mL; P< 0.01) and in normal controls (1.26 [0.93, 1.75] ng/mL; P<0.01). Sensitivity, specificity, positive predictive value, and negative predictive value for Cyfra 21-1 were 70.4%, 81.2%, 49.6%, and 91.3%, respectively. The area under the curve for Cyfra 21-1 was 0.839 (95% confidence interval, 0.802-0.877). Conclusions: We concluded that Cyfra 21-1 may be useful in the diagnosis of lung cancer. 배경: 폐암은 전 세계적으로 가장 치명적인 암 중의 하나이다. 혈청 사이토케라틴분절 21-1 (Cytokeratin fragment 21-1, Cyfra 21-1) 측정은 폐암의 진단에서 좋은 민감도와 특이도를 지닌 종양 표지자로 알려져 있다. 본 연구에서 폐암의 선별 검사로 Cyfra 21-1의 유용성을 평가하고자 한다. 방법: 연구 대상은 건양대학교 병원을 방문한 폐암 환자 169명, 양성 폐질환자 124명, 정상 건강검진자 521명으로 총 814명을 후향적으로 분석하였다. 혈청 Cyfra 21-1은 Architect CYFRA 21-1 kit를 이용하여 Architect i2000 분석기에서 측정하였다. 결과: 폐암 환자에서 Cyfra 21-1의 중앙값 및 사분범위(비소세포성 폐암: 3.16 [1.98, 9.00] ng/mL, 소세포성 폐암: 3.32 [2.07, 5.20] ng/mL)는 양성 폐질환자(1.50 [1.17, 2.17] ng/mL) 및 정상 군(1.26 [0.93, 1.75] ng/mL)보다 통계적으로 유의하게 높았다(각각 P<0.01). Cyfra 21-1의 민감도, 특이도, 양성 예측치, 음성 예측치는 각각 70.4%, 81.2%, 49.6%, 91.3%였다. 또한 Cyfra 21-1의 곡선하면적은 0.839 (95% confidence interval 0.802-0.877)였다. 결론: 본 연구 결과 Cyfra 21-1은 폐암을 진단하는 데 유용한 종양 표지자임을 확인할 수 있었다.

Severe Fever with Thrombocytopenia Syndrome Mimicking Scrub Typhus: Three Case Reports

송성욱,유승진,유정래,이근화,김재왕,허상택 대한응급의학회 2015 大韓應急醫學會誌 Vol.26 No.4

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease in South Korea with clinical features similar to those of scrub typhus. Infected patients with these two diseases usually visited the emergency department (ED) complaining of fever that was not responsive to treatment in a local clinic. Aggressive management of SFTS is required in order to prevent rapid progression and human-to-human transmission, thus rapid and accurate differential diagnosis of the two diseases in the ED is important. We reported three laboratory confirmed cases of SFTS during 2013-2014 in a single center, with fever, skin lesions, and history of outdoor activities in order to help in differential diagnosis between SFTS and scrub typhus in the ED.

Antibiotic Resistance Mechanisms of Escherichia coli Isolates from Urinary Specimens

송성욱,이은영,고은미,하호성,정호중,배일권,정석훈 대한진단검사의학회 2009 Annals of Laboratory Medicine Vol.29 No.1

Background : This study was designed to characterize urinary isolates of Escherichia coli that produce extended-spectrum β-lactamases (ESBLs) and to determine the prevalence of other antimicrobial resistance genes. Methods : A total of 264 non-duplicate clinical isolates of E. coli were recovered from urine specimens in a tertiary-care hospital in Busan in 2005. Antimicrobial susceptibility was determined by disk diffusion and agar dilution methods, ESBL production was confirmed using the double-disk synergy (DDS) test, and antimicrobial resistance genes were detected by direct sequencing of PCR amplification products. E. coli isolates were classified into four phylogenetic biotypes according to the presence of chuA, yjaA, and TSPE4. Results : DDS testing detected ESBLs in 27 (10.2%) of the 264 isolates. The most common type of ESBL was CTX-M-15 (N=14), followed by CTX-M-3 (N=8) and CTX-M-14 (N=6). All of the ESBLproducing isolates were resistant to ciprofloxacin. PCR experiments detected genes encoding DHA- 1 and CMY-10 AmpC β-lactamases in one and two isolates, respectively. Also isolated were 5 isolates harboring 16S rRNA methylases, 2 isolates harboring Qnr, and 19 isolates harboring AAC(6’)- Ib-cr. Most ESBL-producing isolates clustered within phylogenetic groups B2 (N=14) and D (N=7). Conclusion : CTX-M enzymes were the dominant type of ESBLs in urinary isolates of E. coli, and ESBL-producing isolates frequently contained other antimicrobial resistance genes. More than half of the urinary E. coli isolates harboring CTX-M enzymes were within the phylogenetic group B2. Background : This study was designed to characterize urinary isolates of Escherichia coli that produce extended-spectrum β-lactamases (ESBLs) and to determine the prevalence of other antimicrobial resistance genes. Methods : A total of 264 non-duplicate clinical isolates of E. coli were recovered from urine specimens in a tertiary-care hospital in Busan in 2005. Antimicrobial susceptibility was determined by disk diffusion and agar dilution methods, ESBL production was confirmed using the double-disk synergy (DDS) test, and antimicrobial resistance genes were detected by direct sequencing of PCR amplification products. E. coli isolates were classified into four phylogenetic biotypes according to the presence of chuA, yjaA, and TSPE4. Results : DDS testing detected ESBLs in 27 (10.2%) of the 264 isolates. The most common type of ESBL was CTX-M-15 (N=14), followed by CTX-M-3 (N=8) and CTX-M-14 (N=6). All of the ESBLproducing isolates were resistant to ciprofloxacin. PCR experiments detected genes encoding DHA- 1 and CMY-10 AmpC β-lactamases in one and two isolates, respectively. Also isolated were 5 isolates harboring 16S rRNA methylases, 2 isolates harboring Qnr, and 19 isolates harboring AAC(6’)- Ib-cr. Most ESBL-producing isolates clustered within phylogenetic groups B2 (N=14) and D (N=7). Conclusion : CTX-M enzymes were the dominant type of ESBLs in urinary isolates of E. coli, and ESBL-producing isolates frequently contained other antimicrobial resistance genes. More than half of the urinary E. coli isolates harboring CTX-M enzymes were within the phylogenetic group B2.

고전소설과 TV드라마 : TV드라마의 한국적 아이콘 창출을 위한 시론

송성욱 국어국문학회 2004 국어국문학 Vol.- No.137

It is a matter of common knowledge that The korean classical novel and TV drama are much the same. The purpose of this paper is to comparative study on the The korean classical novel and TV drama, focusing on the gap and the same between two genre. Novel and TV drama hold the narrative source common, the other hands this source is used in very different conditions. The result that these two genre are very different. Novel shows a historical reality and moral allegiance through something fantastic factor. Korean classical novel is based on the tradition of Taoism and Buddhism, accordingly the representation of a fantastic is being in the natural order of events. And narrative function of the fantastic elements is much various. On the other hand TV drama shows a common emotion which we can experience in daily life. These differences due to another social condition.

고전소설에 나타난 환상적 표상의 몇 가지 층위

송성욱 성심어문학회 2003 성심어문논집 Vol.25 No.-

노령의 농업인에서 짧은 수면 시간과 우울증의 연관성

송성욱,이현정,유정래,오정환 대한수면연구학회 2023 Journal of sleep medicine Vol.20 No.3

Objectives: This study was conducted to identify the association between short sleep duration and depressive symptoms among elderly farmers. Methods: This study analyzed the Safety for Agricultural Injuries of Farmers cohort data collected from September 2015 to June 2018. The data were based on an agricultural survey of the health and behaviors of adult farmers on Jeju Island in South Korea. Depressive symptoms were defined as a score of 8 or higher according to the short form of the geriatric depression scale. Short sleep duration was defined as less than 6 hours of average daily sleep duration. Results: The analysis included 507 participants, aged over 60 years. Of these, 87 (17.2%) demonstrated depressive symptoms. The prevalence of depressive symptoms differed significantly between farmers with <6 h (25.8%) and those with ≥6 h (13.5%) of sleep (<i>p</i>=0.001). Multivariable analyses confirmed that short sleep duration was significantly associated with depressive symptoms (odds ratio=1.876, 95% confidence interval=1.129–3.118). Conclusions: Our findings suggest that short sleep duration increases the risk of depressive symptoms among elderly farmers. Adequate daily sleep duration may prevent depressive symptoms in the population.