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송광규,서영효,전귀옥,최해윤,김종대 대한본초학회 2004 大韓本草學會誌 Vol.19 No.4
Two patients were dignosed as pneumonia through simple chest X-ray. They were suffering from cough, sputum, fever, chilling sign etc. We performed oriental medical treatment like herbal medicine without using western antibiotics. Through those treatments we could get good results. The herb medicine used at this case was mainly Cheongpyebyulgap-san(淸肺鱉甲散). From the results, we could find out that the oriental medical treatments were very effective to reduce inflammatory fever and to care pneumonia. So in order to prevent antibiotics abuse, we have to make more researches into pneumonia, and try to find out more effctive oriental medical therapies for infectious diseases.
인삼양영탕(人蔘養榮湯)이 비소세포 폐암세포(NCI-H520) 이식 마우스에서 항암 및 면역 활성에 미치는 영향
송광규,곽민아,김종대,Song, Kwang-Kyu,Kwak, Min-A,Kim, Jong-Dae 대한한의학방제학회 2013 大韓韓醫學方劑學會誌 Vol.21 No.1
Objectives : The object of this study was to observe anticancer and related immunomodulatory effects of Insamyangyoung-tang extracts (ISYYTe) on non-small cell lung carcinoma (squamous epithelial carcinoma), NCI-H520, xenograft Balb/c nu-nu nude mice. Methods : Three different dosages of ISYYTe, 50, 100 and 200 mg/kg were orally administered once a day for 42 days from 11 days after tumor cell inoculation. Six groups, which are intact control, tumor bearing control, 5-fluorouracil (FU) 30 mg/kg, ISYYTe 50 mg/kg, ISYYTe 100 mg/kg, ISYYTe 200 mg/kg, each of 8 mice per group were used in the present study. Changes on the body weight, tumor volume and weight, lymphatic organ (spleen and popliteal lymph node), serum interferon (IFN)-${\gamma}$ levels, splenocytes NK cell activity and peritoneal macrophage activities, splenic tumor necrosis factor (TNF)-${\alpha}$, interleukin (IL)-$1{\beta}$ and IL-10 contents were observed with tumor mass and lymphatic organ histopathology to detect anticancer and immunomodulatory effects. Results : As results of ISYYTe 50, 100 and 200 mg/kg treatment, decreases in the tumor volumes and weights were detected. At histopathological observations, decreases of tumor cell volumes in tumor masses were dose-dependently decreased mediated by increases of apoptosis among tumor cells by treatment of all three different dosages of ISYYTe. As results of tumor cell inoculation, marked decreases of spleen and popliteal lymph node weights, serum IFN-${\gamma}$, splenic TNF-${\alpha}$, IL-$1{\beta}$ and IL-10 contents and splenocytes were observed with histopathological atrophic changes of spleen and popliteal lymph nodes. Conclusions : Over 50 mg/kg of ISYYTe showed favorable anticancer effects on the NCI-H520 cell xenograft with immunomodulatory effects. Although relatively lower anticancer effects were observed in ISYYTe 200 mg/kg treated mice as compared with 5-FU 30 mg/kg treated mice, there are no meaningful favorable immunomodulatory effects were observed after 5-FU treatment in the present study.
청상보하탕(淸上補下湯)으로 호전된 위증환자 치험(治驗) 1례(例)
송광규,조동희,최해윤,김종대,전귀옥,Song, Kwang-Kyu,Cho, Dong-Hee,Choi, Hae-Yun,Kim, Jong-Dae,Jeon, Kwi-Ok 대한한방내과학회 2005 大韓韓方內科學會誌 Vol.26 No.3
Wei symptom is muscle relaxation to the point of no contraction and occurs in the limbs. Several cases have led to death. This is a clinical report of a Wei symptom patient diagnosed with impairment of body fluid due to lung heat(肺熱傷津). This patient was treated with Chungsangboha-tang(Qingshangbuxia-tang) and had significant improvement in Wei symptom. Results suggest that oriental medicine is an effective treatment for Wei symptom. But more clinical case reports are needed.
송광규 ( Song Gwang Gyu ),박미연 ( Park Mi Yeon ),김대준 ( Kim Dae Jun ),최해윤 ( Choe Hae Yun ),김종대 ( Kim Jong Dae ) 대한본초학회 2003 大韓本草學會誌 Vol.18 No.4
Fever is rising one`s temperature from various reasons or feeling like having fever even if the temperature is normal. Unbalanced equilibrium of Yin and Yang from the exogenous pathogenic factors or the internal damage is usually considered to be the cause of fever in the Oriental medicine. The fever from deficiency of Qi is a one of the major component of the theory about the fever due to internal damage. In clinic, these kind of cases are observed generally along with wasting disease and no high fever, and the treatment for this may be the complement of Qi. Li Dongyuan(李東○) embodied this idea in a prescription called Bojoongikkitang. And now we are reporting a case which showed many improvements of symptoms by taking Bojoongikkitang after we diagnosed as fever from the deficiency of Qi. But, more clinical case reports are needed.
암성 악액질(cancer cachexia)의 한약치료에 대한 고찰 : 2000~2009년까지 중의논문을 중심으로
송광규(Kwangkyu Song),박미연(Meeyeon Park),최해윤(Haeyun Choi),김종대(Jongdae Kim) 한국한의학연구원 2010 한국한의학연구원논문집 Vol.16 No.2
Objetcives : Cancer cachexia is a common syndrome in advanced cancer patients, which is characterized by profound changes in protein, fat and carbohydrate metabolism , resulting in anorexia, weight loss, muscle wasting and poor performance status. We studied the journals of Chinese herb medicine about cancer cachexia and reported the results. Methods : This study attempted to analyze the contents of the research papers concerning the treatment of cancer cachexia presented in the journals of Chinese medicine published in China over the period between 2000 and 2009. Results & Conclusions : The principles for medical treatment were invigorating Ki(益氣), invigorating the spleen(健脾), regulating the stomach(和胃), nourishing the blood(養血), nourishing Eum(補陰), promoting the circulation of Ki(行氣), removing the phlegm(化痰), removing blood stasis(祛瘀) etc. The used herbs were Poria(茯笭), Astragali Radix(??), Atractylodis Macrocephalae Rhizoma(白朮), Codonopsis Pilosulae Radix(黨蔘), Dioscoreae Rhizoma(山藥), Citri Pericarpium(陳皮), Angelicae Gigantis Radix(當歸), Coicis Pemen(薏苡仁), Paeoniae Radix Alba(白芍藥) etc. The effetcive rate of treatment with Chinese herb medicine group was comparable or even more effetcive. Chinese herb medicine group had little side effetcs. Chinese medicine herb treatment to inhibit cancer cachexia has many possibilities.
보중익기탕가미방(補中益氣湯加味方)으로 호전된 만성 방광염 환자 처험1례 -IPSS 변화를 중심으로-
박송기,송광규,전귀옥,조동희,신현철,강석봉,권은희,Park, Song-Kee,Song, Kwang-Kyu,Jeon, Kwi-Ok,Cho, Dong-Hee,Shin, Hyeon-Cheol,Kang, Seok-Bong,Kwon, Eun-Hee 대한한방내과학회 2005 大韓韓方內科學會誌 Vol.26 No.2
Objectives: This study was designed to evaluate the effects of an oriental medicine therapy, namely Bojoongikkitang-gamibang, on a chronic cystitis patient. Methods: The clinical data was analyzed on a patient with chronic cystitis due to Bigiheoyak(脾氣虛弱) and Junggihaham(中氣下陷) whose main symptoms were urinary disturbances, such as urgency, weak stream, hesitancy and nocturia, etc. The patient visited twice at the internal medicine department of Dae-Gu Hanny University Dae-Gu Oriental Medicine Hospital on May 20, and on June 3, 2004 and was only treated with herbal medicine(Bojoongikkitang-gamibang). Results: After treatment, improvement was seen in the subsection of the International Prostate Symptom Score(IPSS). Conclusions: This study suggests that Bojoongikkitang-gamibang is significantly effective in treatment of a chronic cystitis.
박송기,권은희,송광규,전귀옥,신현철,강석봉,문정환,Park, Song-Gi,Kwon, Eun-Hee,Song, Kwang-Kyu,Jeon, Kwi-Ok,Shin, Hyun-Cheol,Kang, Seok-Bong,Moon, Jung-Hwan 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.3
Diabetes mellitus is a metabolic disorder characterized by hyperglycemia which results from one or both of decreased insulin secretion and increased insulin resistance. Chronic hyperglycemia causes damage to the eyes, kidneys, nerves, heart and blood vessels. The major goal in treating diabetes mellitus is controlling elevated blood sugars without causing abnormally low levels of blood sugar. A 67-year-old woman was admitted with hyperglycemia, thirst, Lt. leg numbness and both leg weakness. The patient was diagnosed as So-gal(消渴) due to dry ness-heat based on yin-deficiency(陰虛燥熱) through oriental medicine and NIDDM through western medicine. The patient was treated with oriental and western medicines. Specifically herbal medicine(Gamijihwangtang), acupuncture, moxa theraphy were used as well as oral medications. Clinical symptoms improved and hyperglycemia dramatically stablized.