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손지우,이정욱,이병순,노운섭,이병주,신조영,이시형,Son, Ji-Woo,Lee, Jung-Wook,Lee, Byung-Soon,No, Woon-Serb,Lee, Byung-Ju,Shin, Jo-Young,Lee, Si-Hyeong 대한한의정보학회 2007 大韓韓醫情報學會誌 Vol.13 No.1
Interstitial lung disease (ILD) is characterized by progressive scarring of the lung leading to restriction and diminished oxygen transfer. Clinically, the presenting symptoms of ILD are nonspecific (cough and progressive dyspnea on exertion) and are often attributed to other diseases, thus delaying diagnosis and timely therapy. In this study, I analyzed the 10 chinese papers of interstitial lung diseases(ILD). The etiology are body resistance weakness(本虛) and pathogenic factor prevailing(標實). The body resistance weakness(本虛) including deficiency of the lung(肺虛), deficiency of the kidney(腎虛), deficiency of the spleen(脾虛), deficiency of Qi and Yin(氣陰兩虛), pathogenic factor prevailing(標實) including stagnation of phlegm(痰濁), blood stasis(瘀血), noxious heat(熱毒). As an treatment aim at supplementing lung and kidney(益肺腎), resolving phlegm and blood stasis(化痰瘀).
가미사군자탕(加味四君子湯)이 OVA로 유발된 천식 마우스에 미치는 영향
손지우,신조형,이시형,Son, Ji-Woo,Shin, Jo-young,Lee, Si-Hyeong 대한한방내과학회 2008 大韓韓方內科學會誌 Vol.29 No.2
Objective : The purpose of this study was to investigate the effects of Gamisagunja-tang(GS) on the airway hyper-reactivity (AHR), cytokine production and T cell activation during the ovalbumin (OVA)-induced allergic asthma in mice. Materials and Methods : BALB/c mice were sensitized and challenged with 100 mg of OVA and 1 mg of aluminum potassium sulfate intraperitoneally on days 1 and 7. On day 14, mice were challenged on 3 consecutive days with 5% OVA. AHR and bronchoalveolar fluid (BALF), total inflammatory cell count and the production of cytokines were measured. Results : GS significantly suppressed the infiltration of inflammatory cells in the lung tissue and AHR. GS significantly down regulated the production of IL-4, IL-5 and increases of $INF-{\gamma}$ in BALF. GS reduced the population of eosinophils from lung and spleen in OVA-induced allergic asthma. GS reduced the population of $CD4^{+}$ $CD69^{+}$ $CD25^{-}$ T cells in OVA-induced allergic asthma Conclusion : These results suggest that GS may inhibit the production of IL-4, IL-5 and infiltration of eosinophils and be beneficial oriental medicine for allergic asthma.
손지우,이정욱,이병순,노운섭,이병주,김동민,김영두,신조영,이시형,Son, Ji-Woo,Lee, Jung-Wook,Lee, Byung-Soon,No, Woon-Serb,Lee, Byung-Ju,Kim, Dong-Min,Kim, Young-Du,Shin, Jo-Young,Lee, Si-Hyeong 대한한의정보학회 2007 大韓韓醫情報學會誌 Vol.13 No.1
Cough is not only serves to maintain normal function of respiratory tract, but also many diseases may lead to this symptom. In Korean medicine, Zhudanxi(朱丹溪), was the first to classify cough according to the different stages of time. In this research, I investigated the stage of Nocturnal Cough(夜嗽) through 26 oriental medical books. As a result, deficiency of Yin(陰虛) was the most common causes of Nocturnal Cough and indigestion(食積) is the next. Liuweidihuang-tang(六味地黃湯) prescribed as the treatment for Yin Xu(陰虛) and Xeibaisan-jiawei(瀉白散加味) prescribed as the treatment for indigestion(食積).
중풍 환자의 사상체질 유형별 혈중지질 분포에 대한 상관성 연구
이민구,박세욱,손지우,김대중,강백규,박상무,이인,문병순,이선우,Lee, Min-Goo,Park, Sae-Wook,Son, Ji-Woo,Kim, Dae-Joong,Kang, Baek-Gyu,Park, Sang-Moo,Lee, In,Moon, Byung-Soon,Lee, Sun-Woo 대한한방내과학회 2006 大韓韓方內科學會誌 Vol.27 No.2
Objectives : This study was executed in order to examine relationship between Sasang constitution and serum lipids in CVA patients. Method and Results : This study was done with 104 cases of stroke patients who admitted to department of the internal medicine Wonkwang university oriental hospital from September in 2004 to August in 2005. A study on the relationship among serum lipids : In T-cholesterol and triglyceride, T-cholesterol and HDL-cholesterol, LDL-cholesterol and HDL-cholesterol. T-cholesterol and LDL-cholesterol, they had positive correlation each other. Between triglyceride and HDL-cholesterol, they had negative correlation each other. Distribution of serum lipids which it follows in stroke type : T-cholesterol, HDL-cholesterol and LDL-cholesterol average of cerebral hemorrhage is higher than cerebral infarction. Distribution of serum lipids which it follows in Sasang constitution : T-cholesterol, triglyceride and LDL-cholesterol average of Taeyumin was higher than different types of Sasang constitution But it didn't have no statistically consideration Conclusions : The relationship between Sasang constitution and Serum lipids was not proven.
이선우,윤종민,손지우,강백규,박상무,윤효진,김대중,김태진,이인,신용일,문병순,Lee, Sun-Woo,Yun, Jong-Min,Son, Ji-Woo,Kang, Beak-Gyu,Park, Sang-Moo,Yun, Hyo-Jin,Kim, Dae-Joong,Kim, Tae-Jin,Lee, In,Shin, Yong-Il,Moon, Byung-Soon 대한한방내과학회 2007 大韓韓方內科學會誌 Vol.28 No.3
Objectives : This study was executed in order to evaluate the effects of electroacupuncture on upper-extremity spasticity control in stroke patients. Methods : Eighteen patients with stroke were enrolled and classified into two groups, the study and control group. The control group did not receive any oriental medical treatment. In the study group, the electroacupuncture points were applied to Kokt'aek (PC3) and $Ch'{\u{o}}ch'{\u{o}}n$ (PC2), Naegwan (PC6) and $Ch'{\u{o}}kt'aek$(LU5) of the affected limb. H-reflexl M-response ratio (HIM ratio), modified Ashworth scale (MAS) and Fugl-Meyer motor function assessment (FMA) were used for evaluation of spasticity control before electroacupuncture, within two hours after electroacupuncture, and at two weeks. Results : In MAS, the study group declined more than the control group. but there was no statisticallysignificant consideration. In H/M ratio. the study group was more efficient than the control group. and spasticity decreased successively during the series in the study group. In FMA, motor function in the study group improved more than in the control group and motor function in the study group increased successively during the series. Conclusions : These results showed that electro acupuncture was a useful method to decrease upper-extremity spasticity in patients with stroke. Further studies are needed to explore more cases and the long-lasting carryover effects on upper-extremity spasticity in electroacupuncture.
뇌졸중 환자의 하지 강직에 대한 음양경락별 전침의 효과
박세욱,이민구,이선우,강백규,손지우,박상무,이인,문병순,Park, Sae-Wook,Lee, Min-Goo,Lee, Sun-Woo,Kang, Baek- Gyu,Son, Ji-Woo,Park, Sang-Moo,Lee, In,Moon, Byung-Soon 대한한방내과학회 2006 大韓韓方內科學會誌 Vol.27 No.2
Objectives : The aim of this study is to review the effects of acupuncture on lower limb spasticity control in stroke patients. Methods: H-reflex/M-response ratio and Modified Ashworth Scale was used for evaluation of spasticity control before acupuncture, within one hours after acupuncture , at twenty-four hours, and four weeks. We divided two groups. One is the yin meridian acupunctured goup and the other is the yang meridian acupunctured group. Results: H/M ratio is declined within 1 or 24 hours after acupuncture for poststroke spasticity patients. The yin meridian acupunctured group is a bit more efficient than the yang meridian acupunctured goup. But there is no meaning in the statistics because of small patient pool. Conclusions: We need more patients group to decide the effect of electro- acupuncture on leg spasticity of stroke patients.
식적(食積) 및 음허(陰虛)로 인한 해수 환자의 임상적 특성 분석
이정욱,박상무,강백규,한덕진,나란희,방창호,장석오,손지우,이시형,Lee, Jung-Wook,Park, Sang-Moo,Kang, Baek-Gyu,Han, Deok-Jin,Na, Ran-Hee,Bang, Chang-Ho,Jang, Seak-Oh,Son, Ji-Woo,Lee, Si-Hyeong 대한한방내과학회 2009 大韓韓方內科學會誌 Vol.30 No.1
Cough is a common clinical problem to which various etiologies are attributable. In Korean medicine there are differentiations in etiology such as food-accumulation and Yin-deficiency. This study was aimed to analyze the relations between the time of cough and Korean syndrome differentiations and to compare the symptoms of Korean syndrome differentiations (food-accumulation and Yin-deficiency). Sixty-two cough patients were analyzed and classified into one of two syndrome differentiations by etiology. We compared the time of coughing and symptomatic characteristics of two: such as symptom differences and change of severity after treatment. Patients with food-accumulation were more prevalent than patients with Yin-deficiency. Among symptoms, anorexia, dyspepsia, nausea and nasal discharge were more prevalent in food-accumulation while pruritus of throat was prevalent in Yin-deficiency. Coughing at night was prevalent in Yin-deficiency and coughing at rising hour was prevalent in food-accumulation.
침치료가 뇌졸중으로 인한 구음장애에 미치는 음향적 특성에 대한 증례보고
이민구,박세욱,이선우,유현희,이승언,김용정,손지우,임은경,김성남,이인,문병순,윤종민,Lee, Min-Goo,Park, Sae-Wook,Lee, Sun-Woo,Ryu, Hyun-Hee,Lee, Seung-Eon,Kim, Yong-Jeong,Son, Ji-Woo,Rhim, Eun-Kyung,Kim, Sung-Nam,Lee, In,Moon, Byung-Soon 대한한방내과학회 2005 大韓韓方內科學會誌 Vol.26 No.3
Objectives : The aim of this study is to find the acoustic characteristics of acupuncture therapy effects on post-stroke dysarthria. Methods : Acupuncture therapy was applied for four to six weeks by inserting needles into eight acupuncture points, CV23, CV24, bilateral 'Sheyu' and ipsilateral ST4, ST6 and contralateral LI4, ST36 on facial palsy side. All the speech samples were collected, pre-treatment and post-treatment, using Computerized Speech Lab. VOT and TD of each speech sample and vowel formant(F1&F2) were analyzed on spectrogram. Result : VOT and TD were decreased after treatment. F1 was decreased, and F2 was increased after treatment. Conclusions : This suggests that acupuncture therapy improves symptoms of post-stroke dysarthria by stimulating articulation organs such as tongue, lips, cheeks, larynx and pharynx.