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      • KCI등재

        Pseudomonas sp . EL-091S 에 의한 4-Chlorophenol의 분해 Kinetics

        손준석,이건,이상준 한국환경과학회 1993 한국환경과학회지 Vol.2 No.2

        In order to find the most fitted biodegradation model, biodegradation models to the initial 4-chlorophenol concentrations were investigated and had been fitted by the linear regression. The degrading bacterium, EL-091S, was selected among phenol-degraders. The strain was identified with Pseudomonas sp. from the result of taxonomical studies. The optimal condition for the biodegradation was as fellows: secondary carbon source, concentration of ammonium nitrate, temperature and pH were 200㎎/l fructose, 600 ㎎/l, 30℃ and 7.0 respectively. The highest degradation rate of the 4-chlorophenol was about 58% for 24 hours incubation on the optimal condition. Biodegradation kinetics model of 5 ㎎/l 4-Chlorophenol, 10 ㎎/l 4-chlorophenol and 50 ㎎/l 4-chlorophenol were fitted the zero order kinetics model, respectively.

      • KCI등재

        일개 도시 성인의 성별에 따른 대사증후군 관련요인의 차이

        손준석,조병만,김영욱,채창호,김찬우,김자현 대한임상건강증진학회 2012 Korean Journal of Health Promotion Vol.12 No.1

        Background: Metabolic syndrome is a major risk factor for cardiovascular disease. The combination of an aging population with a chronic diseased population is leading to an increase in the mortality rate due to cardiovascular diseases. The purpose of this study was to assess the prevalence of metabolic syndrome in the Korean population and to evaluate its related factors for sex differences. Methods: From April 2007 to December 2008, a total of 2,729 volunteers aged 40-69 years living in Changwon city underwent a clinical examination at a hospital in Changwon, Korea. Metabolic syndrome was diagnosed following the criteria defined in Circulation 2009. The clinical examination included measuring anthropometric variables and cardiovascular risk factors, while lifestyle factors were assessed through a questionnaire. Results: The prevalence of metabolic syndrome in our sampling pool was 25.2% with a break down by sex showing a rate of 30.2% in men and 22.2% in women. Related factors associated with metabolic syndrome common to both sex were age, self-health assessment, and alcohol consumption. Sleep duration seemed to be a related factor in men, while income, education, and menstruation status played significant roles in women. Conclusions: To better manage metabolic syndrome, men need to be educated on alcohol use and women of low socioeconomic status require particular attention as do the aging population and postmenopausal women. 연구배경: 대사증후군은 심혈관계 질환의 주된 위험인자인 고혈당, 고혈압, 고지혈증, 복부비만 등이 동시에 발생하는 일종의 질환군이다. 노령인구의 증가와 이러한 만성질환의 증가로 인하여 심혈관계질환으로 인한 사망률이증가되고 있다. 본 연구에서는 일개도시에 거주하는 인구에서 남녀 간의 대사증후군과 구성요소, 그에 영향을 주는관련요인들의 차이를 분석하고자 시행하였다. 방법: 2007년 4월부터 2008년 12월까지 경남 창원에 소재한 종합병원에서 국민의료보험공단에서 실시하는 성인병 및 암검진을 받기 위해 내원한 경남 창원에 거주하는40세 이상에서 69세 이하까지의 성인들 중 연구에 참여하기로 동의한 2,729명을 대상으로 하였다. 연구대상자들에대하여 인구사회학적지표, 생활습관, 주관적 건강인식과스트레스 정도에 대하여 일대일 면담을 통해 구조화된 설문지를 작성하였고 대사증후군과 관련된 검사를 시행하였다. 결과: 대사증후군의 유병률은 전체 25.2%였고 남성은30.2%, 여성은 22.2%로 나타났다. 대사증후군의 유병률은연령이 증가할수록, 건강하다고 생각할수록 높았고 남성에서는 음주의 양이 증가할수록 대사증후군의 유병률이증가하였으나 여성에서는 반대의 결과로 나타났다. 여성에서는 소득수준, 교육수준, 결혼상태에 따라 대사증후군의 유병률과 관계가 있었다. 특히 폐경 후 여성에서는 대사증후군의 유병률이 급격히 높아지는 것으로 나타났다. 결론: 대사증후군을 관리하기 위해서는 남성에서는 음주습관에 대한 교육이 필요하며, 여성의 경우에는 사회경제적환경이 낮은 계층에 대한 관심이 필요하다. 또한 연령이높을수록 그 위험이 증가하여 노령인구와 특히 여성의 경우폐경 후의 여성에 대하여는 중점적인 관리가 필요하다.

      • KCI등재

        12주간 high-speed 탄력 밴드 운동이 농촌 고령자의 신체 수행 능력과 근기능에 미치는 영향

        손준석,강동헌,윤동현,김대영,김희재,김장회,소병훈,송한솔,황수승,송욱 대한임상건강증진학회 2015 Korean Journal of Health Promotion Vol.15 No.4

        Background: Aging related decrease in muscle strength and flexibility leads to functional loss of physical ability. Power training is known to improve these capacities and helps in performing daily routine better. Therefore, we modified previously proven and certified sarcopenia intervention exercise for elderly in rural community and applied them to examine the effects on physical fitness and muscle functions to show its applicability. Methods: Subjects were divided into control and exercise group using single-blind method. Exercise group underwent high-speed elastic band training(concentric contraction in 1 second) 2 days per week for 12 weeks. Before and after the intervention, we performed body composition analysis, anthropometric measurement, blood test, blood pressure check, senior fitness test (SFT), upper body and lower body strength examination. Korean version of Physical Activity Scale for the Elderly (K-PASE), and Center for Epidemiological Studies- Depression Scale (CES-D) were also assessed. Results: Body weight in control group was significantly increased (Paired t-test: P=0.008), although it was consistent in exercise group (Group×Time: P=0.013). 30-second chair stand (P<0.001) and 30-second arm curl (P<0.001) of the senior fitness test were also significantly improved in exercise group compared to control. In addition, muscle strength of knee flexion (P=0.034) and K-PASE score (P<0.001) were improved in training group with statistical significance. Conclusions: The modified high-speed elastic band training for rural elderly improved muscle strength and daily physical performance. This result suggests a simple and easy to perform band training could be an excellent solution to prevent sarcopenia in rural elderly. It also supports the evidence that this program would be widely distributed. 연구배경: 노화로 인한 신체 수행 능력의 감소는 신체 움직임의 기능적 손실을 야기한다. Power training은 근육의파워와 기능을 향상시키고, 나아가 일상생활을 수행하는데도움을 준다. 따라서 본 연구에서는 선행 연구에서 효과가검증된 근감소증 중재 운동 방법을 보완 및 적용해 농촌맞춤형 운동 중재 방법으로써 효과를 검증하고자 한다. 방법: 본 연구는 단일맹검 무작위 방법으로 대상을 대조군과 운동군으로 분류하였으며 탄력 밴드를 이용해 12주동안 주 2회의 high-speed 탄력 밴드 운동(1초 동안 단축성수축 실행)을 실시하였다. 운동 중재 전후에 신체조성 및계측, 혈액검사, 노인체력검사와 상, 하지 근력검사, 우울척도 그리고 신체활동설문지를 통해 운동 효과를 증명하였다. 결과: 대조군의 체중에서 사전 값에 비해 사후 값에서 통계적으로 유의하게 증가(Paired t-test: P=0.008)했지만 운동군에서는 체중의 변화가 나타나지 않았다(Group × Time: P=0.013). 운동군에서는 대조군에 비해 노인체력검사 항목중 30초 동안 의자에 앉았다 일어나기(P<0.001)와 아령 들기(P<0.001) 검사에서 통계적으로 유의하게 개선되었으며knee flexion 근력 검사(P=0.034)와 신체활동설문지(P<0.001) 검사에서도 통계적으로 유의하였다. 결론: 본 연구를 통해, high-speed 탄력 밴드 운동을 적용한 운동 중재가 농촌 노인의 체력과 근력을 향상시키고, 일상 생활 수행 능력을 개선시키는데 효과가 있음을 확인하였다. 이러한 결과는 간편하고 쉬운 동작의 밴드 운동이 농촌 노인들의 근감소증을 예방할 수 있는 운동 프로그램으로 보급 및 확산될 수 있는 근거를 제시한다.

      • KCI등재후보

        일부 채용건강진단 대상자의 척추분리증 유병률에 관한 연구

        손준석,김영욱,이철호,채창호,조병만,김자현 대한척추신경외과학회 2009 Neurospine Vol.6 No.4

        Objective: In Korea, there appears to be an increase in the diagnosis of lumbar spine disorders recently. This trend has urged employers to screen new employees for this disorder. One of the methods for the investigation is the radiological examination of the lumbar spine. We studied the prevalence of spondylolysis according to age and sex with lumbar X-ray (anterior-posterior view and lateral view) of new employees in pre-employment screening examination. We also estimated the outbreak period of spondylolysis by analysing the prevalence rates at each age group, which were the results of our study. Methods: We gathered the data of lumbar X-ray findings for new employees, who had recieved pre-employment screening examinations in the department of occupational and environmental medicine of Masan Samsung Hospital Korea during a period from January 1, 2002 to December 31, 2005. We analyzed the data to obtain the age and sex prevalence of spondylolysis and spina bifida. Results: The prevalence of spondylolysis for the pre-employment screening examination was 5.9% (male 6.6%; female 4.3%) in this study. The prevalence of spondylolysis after adjusting age and sex was 9.0%. The prevalence of spondylolysis was positively correlated with age, and showed to be higher in female than male. Body mass index of spondylolytic subjects was higher than that of normal. The prevalence of spondylolysis was significantly higher in those with spina bifida than normal subjects. Conclusion: The prevalence of spondylolysis of the pre-employment screening examination was 5.9% in this study. The factors which relates with spondylolysis were age, BMI and the prevalence of spina bifida. Objective: In Korea, there appears to be an increase in the diagnosis of lumbar spine disorders recently. This trend has urged employers to screen new employees for this disorder. One of the methods for the investigation is the radiological examination of the lumbar spine. We studied the prevalence of spondylolysis according to age and sex with lumbar X-ray (anterior-posterior view and lateral view) of new employees in pre-employment screening examination. We also estimated the outbreak period of spondylolysis by analysing the prevalence rates at each age group, which were the results of our study. Methods: We gathered the data of lumbar X-ray findings for new employees, who had recieved pre-employment screening examinations in the department of occupational and environmental medicine of Masan Samsung Hospital Korea during a period from January 1, 2002 to December 31, 2005. We analyzed the data to obtain the age and sex prevalence of spondylolysis and spina bifida. Results: The prevalence of spondylolysis for the pre-employment screening examination was 5.9% (male 6.6%; female 4.3%) in this study. The prevalence of spondylolysis after adjusting age and sex was 9.0%. The prevalence of spondylolysis was positively correlated with age, and showed to be higher in female than male. Body mass index of spondylolytic subjects was higher than that of normal. The prevalence of spondylolysis was significantly higher in those with spina bifida than normal subjects. Conclusion: The prevalence of spondylolysis of the pre-employment screening examination was 5.9% in this study. The factors which relates with spondylolysis were age, BMI and the prevalence of spina bifida.

      • KCI등재

        고압전류 감전자에게서 나타난 말초신경병증 증례보고

        손준석,김영욱,채창호,민경범,이철호 대한산업의학회 2006 대한직업환경의학회지 Vol.18 No.4

        Background: With increasing industrial development, opportunities are growing to contact electricity in the workplace or home. Therefore, the risk of electrical accident has been increased gradually. In general, electrical injuries involve the extremities and result in amputation or severe disability of limbs. Delayed spinal cord injury and peripheral neuropathies following electrical accidents are extremely rare. Case report: A 32-year-old man with 10 years working experience at a CRT-monitor manufacturer with repetitive exposures to high voltage current visited our hosipital. He complained of left leg weakness and atrophy, and intermittent pain. The symptoms were progressive. Other symptoms occurred such as nocturia, hesitancy, and weak urinary stream. We examined the patient and conducted EMG, L-spine MRI, neurometer test, isokinetic strength test, and physical examination. The results showed neural injuries due to anterior horn lesions or compression of the left femoral nerve pathway, with a consequent diagnosis of neurogenic bladder.

      • KCI등재

        건강한 한국 성인 남성에서 골밀도와 중성지방의 상관관계

        손준석,고현민,박종경 대한임상건강증진학회 2015 Korean Journal of Health Promotion Vol.15 No.3

        Background: As the elderly population increasing, the interest in osteoporosis, hyperlipidemia, and cardiovascular diseases has increased in recent years. In accordance with such trend, many studies regarding correlations between bone density and hyperlipidemia have been conducted. However, the study outcomes have been inconsistent so far, and most of the studies focused on females. Therefore, this study aimed to investigate the correlation between serum lipid levels and bone density in healthy Korean male adults. Methods: This study surveyed 851 male adults, who visited an examination center at a university hospital, on smoking, drinking, hypertension, and diabetes history. A laboratory examination measured total cholesterol, triglyceride, low density lipoprotein cholesterol, high density lipoprotein cholesterol, apolipoprotein A-1, and apolipoprotein B. For bone density, lumbar, femoral neck, and femur were measured using dual energy X-ray absorptiometry. Results: Body mass index (BMI) and bone density T-value showed a positive correlation. Triglyceride exhibited a positive correlation with bone density T-value, and they still revealed a significant positive correlation after correcting for age and BMI. While high density lipoprotein cholesterol showed a negative correlation with bone density, they were not correlated significantly after correcting for age and BMI. There was no correlation found between low density lipoprotein cholesterol and bone density. Conclusions: This study confirmed that bone densities of all areas measured were significantly increased in Korean male adults as triglyceride increased. Total cholesterol, high density lipoprotein cholesterol, and low density lipoprotein cholesterol did not show a significant correlation with bone density. 연구배경: 노인 질환의 증가로 골다공증, 고지혈증 및 심혈관 질환에 대한 관심이 증가되었다. 이런 흐름에 따라 골밀도와 고지혈증의 상관관계에 대한 여러 연구가 시행되어왔다. 그러나 지금까지 그 연구 결과가 일치하지 않고, 대부분의 연구가 여성에게 편중되어 있었다. 따라서 본 연구에서는 건강한 한국 남성을 대상으로 혈청 지질 농도와 골밀도 간의 상관관계에 대하여 알아보고자 하였다. 방법: 일개 대학병원 검진센터를 방문한 성인 남성 851 명을 대상으로 설문지를 통하여 흡연, 음주력, 고혈압, 당뇨병 등의 과거력을 조사하였고, 검사실 검사로 총 콜레스테롤, 중성지방, 저밀도지단백 콜레스테롤, 고밀도지단백콜레스테롤, 아포지단백 A-1, 아포지단백 B를 측정하였으며, 골밀도는 이중 에너지 X선 흡수 계측법을 이용하여 요추 골밀도와 대퇴목 골밀도, 대퇴골 골밀도를 측정하였다. 결과: 체질량지수와 골밀도 T 값은 양의 상관관계를 보였다. 중성지방은 골밀도 T 값과 양의 상관관계를 보였으며 나이와 체질량지수를 보정한 이후에도 유의한 양의 상관관계를 보였다. 고밀도지단백 콜레스테롤은 골밀도와 음의 상관관계를 보였으나 나이와 체질량지수를 보정한 이후에는 유의한 상관관계가 없었다. 저밀도지단백 콜레스테롤은 골밀도와 상관관계가 없었다. 결론: 한국인 성인 남성에서 중성지방이 높을수록 모든부위의 골밀도가 유의하게 증가하였음을 확인할 수 있었다. 총 콜레스테롤과 고밀도지단백 콜레스테롤 및 저밀도지단백 콜레스테롤은 골밀도와 유의한 상관관계가 없었다

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