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김종필(Jong Pill Kim),소순남(Soon Nam So),김계정(Kea Jeung Kim),이창우(Chang Woo Lee),강형재(Hyung Jai Kang) 대한피부과학회 1988 대한피부과학회지 Vol.26 No.6
Pemphigua foliaceus is a rare, relatively mild and chronic variety of pemphigus which is characterized by superficial flaccid bullae which show acantholytic changes in the upper part of the epidermis histopathologically. We report herein five cases of pemphigus foliaceus. The patients had erythematous and crusted patches chiefly on face, chest and back areas, except for case 2 who had flaccid bullae on the upper extrimities. The diagnosis of all these patients were confirmed by immunofluorescence studies. Among these five patients, one was recognized as a rifampicin induced pemphigus foliaceus, and the other one revealed concurrent lesions of psoriasis.
이진탁(Jin Tack Lee),소순남(Soon Nam So),김중환(Joong Hwan Kim),김재홍(Jae Hong Kim) 대한피부과학회 1988 大韓皮膚科學會誌 Vol.26 No.3
Ceftriaxone is a new semi-synthetic, broad spectrum third generation cephalosporin. It has a high degree of stability in the presence of beta-lactamase and its half-life averages about 8 hours. A total of 109 patients with uncomplicated gonococcal urethritis seen at the VD Clinic, Choong-Ku Public Health Center, in Seoul in the periods of March April 1986, and April-May 1987, were subjected to this study. The diagnosis of gonococcal infection and the test. of cure were made on the basis of culture and Gram staining of urethral smear. The patients were divided randomly into two groups consisting of 49 and 60, and treated with ceftriaxone, 250mg, IM and 500mg, IM respectively. No failure case was seen in both groups. lt is suggested that ceftriaxone, 250mg, IM regimen may be used as the first line treatment for uncomplicated gonococcal urethritis.
桑白皮가 白鼠 腹腔 肥滿細胞에 미치는 影響에 關한 細胞形態學的 硏究
蘇淳南,金禎洙,田炳得,李武三 전북대학교 의과학연구소 1986 全北醫大論文集 Vol.10 No.3
In order to investigate the cytomorphological influences of Cortex Mori on the rat peritoneal mast cells, this study was performed. After the rat peritoneal mast cell are suspended, the following results were obtained ; 1. Within 5 minutes after the addition of compound 38/80 solution(20μg/ml). degranulation of mast cells were induced. 2. Within 30 minutes after the addition of Cortex Mori solution (1mg/ml), degranulation of mast cell was induced. 3. The pretreated mast cells with Cortex Mori solution for 3 minutes did not show degranulation within 30 minutes after the addition of compound 48/80. 4. Within 30 minutes after the addition of solution of which pH and osmolarity equal to those of Cortex Mori solution, degranulation of mast cells was not induced. 5. The mast cells pretreated with solution of which pH and osmolarity equal to those of Cortex Mori solution for 3 minutes, show degranulation within 3 minutes after the addition of compound 48/80 solution. From the above results, it is suggested that the Cortex Mori may have some substances to inhibit the compound 48/80 dependant degranulation of the mast cell although it was not known how Cortex Mori acts on the mast cell. (Key words : Cortex Mori, mast cell)
김중환,김재홍,김영태,소순남 대한감염학회 1988 감염 Vol.20 No.4
Secondary syphilis is a great immitator. When syphilis produce unusual skin lesions, the diagnosis is often difficult and delayed. We report a case of secondary nodular syphilis with features of cutaneous lymphoma. A 52-year-old male patient has had erythematous to brownish nodules with pruritis and generalized lymphadenopathy for about 5 weeks prior to visit to our clinc. The diagnosis was eventually made by a skin biopsy and serologic tests for syphilis. Histopathologically, numerous plasma cells around blood vessles and endothelial hyperplasia were ween in the dermis and Warthin-Starry stain shows Treponema pallidum. Serologic tests revealed that VDRL was reactive at 1:64 dilutions and TPHA was reactive.
김영태,소순남,김성호,김중환 대한감염학회 1988 감염 Vol.20 No.2
Eczema herpeticum, a type of Kaposi's varicelliform eruption, is an uncommon disease and usually found in individuals who have an eczematous atopic dermatitis. We have experienced two cases of eczema herpeticum which occurred in a 21-year-old man and a 2-year-old girl with atopic dermatitis. Typical central umblicated vesicopustules and crusted lesions were seen in both patients. Herpes simplex virus were isolated on monolayers of vero cells from the eczematous lesion and identified by monoclonal antibody (Microtrak, syva) technique.