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급성 호흡기 감염으로 입원한 소아 환자에서 Chlamydia pneumoniae의 임상 양상: Mycoplasma pneumoniae와의 비교
성재진 ( Jae Jin Sung ),김은진 ( Eun Jin Kim ),선용한 ( Yong Han Sun ),전인상 ( In Sang Jeon ),차한 ( Hann Tchah ),류일 ( Eell Ryoo ),손동우 ( Dong Woo Son ),조혜경 ( Hye Kyung Cho ),조혜정 ( Hye Jung Cho ),김나연 ( Na Yeon Kim 대한천식알레르기학회 2015 Allergy Asthma & Respiratory Disease Vol.3 No.5
Purpose: Chlamydia pneumoniae is a common intracellular bacterial pathogen and plays an important role in acute respiratory infections. The purpose of this study was to investigate clinical presentations of C. pneumoniae in children with acute respiratory infections. Methods: We examined the medical records of pediatric patients (age<18 years) admitted with acute respiratory infections of C. pneumoniae to Gachon University Gil Medical Center between March 1, 2011 and August 31, 2014. We compared the clinical features of C. pneumoniae infection with that of Mycoplasma pneumoniae infection. Results: We confirmed acute respiratory infections of C. pneumoniae in 110 patients out of 2,156 patients (5.1%) admitted with acute respiratory infections. The mean age was 37.2±30.1 months. More than half of them (54.5%) had coinfection. C. pneumoniae infection had mild and subacute courses. The mean duration of symptoms prior to admission was 8.5±13.8 days. There were remarkable seasonal variations and prevalence was higher in December and April (P=0.03 and P=0.02, respectively). Although rhinorrhea and pharyngeal injection were more common in C. pneumoniae infection (P<0.05), clinical signs and symptoms were similar between C. pneumoniae and M. pneumoniae. Extrapulmonary manifestations such as skin lesion, Gastrointestinal symptoms, hepatitis, and neurologic symptoms were common (41.0%) in C. pneumoniae infection and, had similar incidence in M. pneumoniae infection. Conclusion: C. pneumoniae is an important infectious agent of acute respiratory infections in children. Clinical pictures of C. pneumoniae are similar to M. pneumoniae, even in extrapulmonary manifestations. C. pneumoniae should be taken into consideration in differential diagnosis of acute respiratory infection in children. (Allergy Asthma Respir Dis 2015;3:346-351)