특수아동을 위한 놀이치료 연구 분석: 1997-2009년까지의 국내 연구를 중심으로

서영은,이영선 한국자폐학회 2009 자폐성 장애연구 Vol.9 No.2

In recent years a growing number of studies employing play therapies for children with special needs were conducted and previous research shows that play therapies were successfully utilized for multiple mental health and concerns as well as psychosocial and behavior supports for children with various disabilities. This study reviewed a body of research using play therapy as a primary intervention, focusing on 34 studies which had been published in Korean journals between 1997 to 2009. The synthesis was conducted in the following categories: research participants, research design, interventions and their effects. The types of intervention were structured group play therapy and non-directive play, therapy and some of interventions included subject's parents or their peers without disabilities. Most of interventions were provided in segregated play therapy room by play therapists. Play therapy was effective for promoting verbal language and social and cognitive development as well as decreasing behavior problems and anxiety level. Based on results from this synthesis, further discussion on the results and implications for further research and practice were entailed. 최근 국내외에서 놀이치료의 수요가 증가하면서 다양한 환경에서 놀이치료가 실시되고 있으며 특수아동들을 대상으로 한 놀이치료 역시 늘어나고 있다. 본 연구는 장애 및 장애 위험 아동들을 대상으로 하는 놀이치료를 다룬 연구들을 종합 분석하여 현재까지의 연구를 정리하고 앞으로의 연구 방향을 제시하고자 하였다. 이를 위하여 놀이치료가 국내에 도입되어 활발하게 시작되어 온 1997년부터 2009년까지 지난 13년간 국내 학술지에 게재된 34편의 논문들을 분석 자료로 활용하여 연구 대상자, 연구 설계, 놀이치료, 중재의 효과를 중심으로 분석되었다. 놀이치료는 구조화된 집단놀이치료와 비지시적 놀이치료로 나누어서 분석이 이루어졌으며, 대부분의 중재들은 부모 참여 및 지원을 제공하고 있었다(부모-아동을 대상으로 한 연구, 부모 상담, 부모 놀이치료 등). 또한 놀이치료는 교실이나 가정보다는 분리된 치료실에서 놀이치료사에 의해서 이루어지는 경우가 대부분이었으며, 놀이치료의 효과는 언어표현 향상, 사회성 향상, 과잉행동 및 부주의 행동 감소, 불안심리 감소, 인지 향상 등으로 나타났다. 분석 결과를 바탕으로 국내 놀이치료 연구 및 현장에서의 특수아동에게 적용을 위한 논의 및 제언이 제시되었다.

섬망 심각도와 관련된 위험 요인

서영은,김태석,원왕연,이창욱,이철 대한신경정신의학회 2010 신경정신의학 Vol.49 No.6

ObjectivesZZThe purpose of this study was to investigate the relationship between the sum of the risk factors for delirium and the severity of delirium and to identify those risk factors which increase the severity of delirium. MethodsZZThe participants were 151 patients who were consulted with a consultation-liaison psychiatrist and diagnosed using DSM-IV criteria as suffering from delirium. Sociodemographic and clinical characteristics were obtained through structured interviews and medical chart reviews. The severity of delirium symptoms was measured by the Korean version of the Delirium Rating Scale-Revised 98 (K-DRS-R98). Patients were divided into two groups : a ‘mild delirium group (MDG)’, whose total scores on the K-DRS-R98 were below 16, and a ‘severe delirium group (SDG)’ with the scores above 16. ResultsZZThere was a positive correlation between the sum of known risk factors for delirium and total scores on the K-DRS-R98 (p=0.009). The SDG showed a significantly higher incidence of abnormal potassium levels, abnormal sodium levels, old age, and polypharmacy than the MDG (p=0.010, p=0.046, p=0.042, and p=0.033 respectively). In a logistic regression model, old age, abnormal sodium and potassium levels, and polypharmacy were found to predict increased severity of the delirium (p=0.001, p=0.007, p=0.019, and p=0.005 respectively). ConclusionZZThe present findings suggested that there are certain factors which not only affect the occurrence of delirium, but also severity of delirium symptoms. ObjectivesZZThe purpose of this study was to investigate the relationship between the sum of the risk factors for delirium and the severity of delirium and to identify those risk factors which increase the severity of delirium. MethodsZZThe participants were 151 patients who were consulted with a consultation-liaison psychiatrist and diagnosed using DSM-IV criteria as suffering from delirium. Sociodemographic and clinical characteristics were obtained through structured interviews and medical chart reviews. The severity of delirium symptoms was measured by the Korean version of the Delirium Rating Scale-Revised 98 (K-DRS-R98). Patients were divided into two groups : a ‘mild delirium group (MDG)’, whose total scores on the K-DRS-R98 were below 16, and a ‘severe delirium group (SDG)’ with the scores above 16. ResultsZZThere was a positive correlation between the sum of known risk factors for delirium and total scores on the K-DRS-R98 (p=0.009). The SDG showed a significantly higher incidence of abnormal potassium levels, abnormal sodium levels, old age, and polypharmacy than the MDG (p=0.010, p=0.046, p=0.042, and p=0.033 respectively). In a logistic regression model, old age, abnormal sodium and potassium levels, and polypharmacy were found to predict increased severity of the delirium (p=0.001, p=0.007, p=0.019, and p=0.005 respectively). ConclusionZZThe present findings suggested that there are certain factors which not only affect the occurrence of delirium, but also severity of delirium symptoms.

Candidemia due to Necrotizing fascitis associated Artificial urinary sphinter

서영은,김어진 대한내과학회 2022 대한내과학회 추계학술대회 Vol.2022 No.2

Minimum Inhibitory Concentration (MIC) of Propionic Acid, Sorbic Acid, and Benzoic Acid against Food Spoilage Microorganisms in Animal Products to Use MIC as Threshold for Natural Preservative Production

서영은,성미선,황정은,윤요한 한국축산식품학회 2023 한국축산식품학회지 Vol.43 No.2

Some preservatives are naturally contained in raw food materials, while in some cases may have been introduced in food by careless handling or fermentation. However, it is difficult to distinguish between intentionally added preservatives and the preservatives naturally produced in food. The objective of this study was to evaluate the minimum inhibitory concentration (MIC) of propionic acid, sorbic acid, and benzoic acid for inhibiting food spoilage microorganisms in animal products, which can be useful in determining if the preservatives are natural or not. The broth microdilution method was used to determine the MIC of preservatives for 57 microorganisms. Five bacteria that were the most sensitive to propionic acid, benzoic acid, and sorbic acid were inoculated in unprocessed and processed animal products. A hundred microliters of the preservatives were then spiked in samples. After storage, the cells were counted to determine the MIC of the preservatives. The MIC of the preservatives in animal products ranged from 100 to 1,500 ppm for propionic acid, from 100 to >1,500 ppm for benzoic acid, and from 100 to >1,200 ppm for sorbic acid. Thus, if the concentrations of preservatives are below the MIC, the preservatives may not be added intentionally. Therefore, the MIC result will be useful in determining if preservatives are added intentionally in food.

포렌식을 위한 MFCC 기반의 오디오 음질 분류 방법

서영은,안상근,이해연 한국정보기술학회 2024 한국정보기술학회논문지 Vol.22 No.1

통신, 엔터테인먼트, 보안 등 다양한 분야에서 오디오의 활용이 증가함에 따라서, 그 음질을 평가하여 응용하는 것이 중요해지고 있다. 특히, 오디오 포렌식 분야에서 오디오의 고음질과 저음질을 신속하게 판별하는 기술은 불법적인 녹취 데이터를 분류하는데 기여한다. 본 논문에서는 변형된 DenseNet 기반의 음질 분류 모델을 통해 오디오의 음질을 판단하는 방법을 제안한다. 3초 단위 오디오를 입력받아, MFCC(Mel-Frequency Cepstral Coefficients)를 이용해 2차원 신호 특징을 추출하였고, 변형된 DenseNet 모델에 적용하여 음질 판단에 활용하였다. 국내외 데이터셋과 자체적으로 수집한 오디오를 사용하여 실험을 수행하였다. CNN 모델을 사용하였을 때 86.7% 정확도를 보였으나, 제안한 변형된 DenseNet 모델을 사용하였을 때 94% 정확도를 달성하였다. As the use of audio increases in various fields such as communication, entertainment, and security, it is becoming more important to evaluate accurately its quality and apply. In particular, the technology to quickly determine the high and low quality of audio can contribute to classify illegal recording data in the field of audio forensics. In this paper, we propose a method of determining the audio quality using a modified DenseNet-based audio quality classification model. When audio in units of 3 seconds was input, the 2D feature of the audio was extracted using Mel-Frequency Cepstral Coefficients(MFCC) and applied to the modified DenseNet model to determine audio quality. Experiments were performed using domestic and foreign datasets and audio collected in-house. Although the accuracy of the CNN model was 86.7%, the proposed modified DenseNet model achieved the accuracy of 94%.

프로바이오틱스의 기능성과 안전성

서영은,윤요한,김세정 한국낙농식품응용생물학회 2019 Journal of Dairy Science and Biotechnology (JMSB) Vol.37 No.2

Probiotics stabilize intestinal microflora, reduce constipation, reduce decay by inhibiting harmful bacteria, and prevent diseases. Probiotics have also been studied for their possible roles in immune activation, treatment of cancer, remediation of cholesterol, treatment of diabetes, alleviation of allergies, and relief of lactose intolerance. However, recent data concerning the side effects of probiotics have prompted debate regarding their efficacy and safety. Major adverse events associated with probiotics are gastrointestinal symptoms, such as diarrhea, gastrointestinal disorders, and vomiting, along with skin rash and urticaria. Probiotics occasionally cause sepsis in infants with poor immunity and elderly people with severe diseases. In contrast to previous studies that described the efficacy of probiotics in intestinal regulation, some recent studies have reported that the activity of intestinal microbes becomes weak as a result of the influx of probiotics. The data indicate that the safety of probiotics is not guaranteed and that further investigations are needed.

축산물이력제를 활용한 수도권에서 유통 중인 한우고기 유통환경조사

서영은,이지선,윤요한 한국축산식품학회 2023 Food and Life Vol.2023 No.3

The objective of this study was to investigate the distribution conditions for Hanwoo in capital area. Hanwoo beef samples(n=206) were collected in Seoul from June 2022 to April 2023. The individual information, distribution time, distributionchannel, and distribution location for the samples were collected with the animal products traceability system. In addition, the exposure temperature of Hanwoo beef from retail stores to the final consumption place was collectedfrom the regional temperature observation data from the Korea Meteorological Administration for the dates the samplecollected. It was found that the proportion of Hanwoo beef distributed in Seoul was the highest in 30–39-month-oldand steers. Regarding the location of each distribution channel, slaughterhouses and meat packaging companies hadthe highest share in Gyeonggi-do. Transport times were 4.3–249.5 min from the slaughterhouse to the meat packagingbusiness, 64.1–141.0 min from the slaughterhouse to the meat sales business, and from 19.4–344.0 min from the meatpackaging business to the meat sales business. Finally, it took 22.0 to 88.0 min from the meat sales business toconsumers. The atmosphere temperature ranges to which Hanwoo beef is exposed from the meat sales business tothe consumer were –2.1℃–28.8℃ in spring and fall, 18.1℃–33.4℃ in summer, and –9.6℃–14.3℃ in winter. Thus, consumersshould not expose Hanwoo beef to a temperature suitable for the microbial growth for a long time during the transportto the final consumption place. This result might be useful in distribution simulation for the microbial fates withthe predictive models and in the microbial risk assessment.

액체배양에 의한 홍국색소 생산의 최적배양조건

서영은,정혁준,홍순명,유대식,Seo, Young-Eun,Jung, Hyuck-Jun,Hong, Soon-Myung,Yu, Tae-Shick 한국미생물학회 2007 미생물학회지 Vol.43 No.1

홍국 색소의 액체배양에 의한 대량생산조건을 개발하기 위하여 Monascus sp. KM 1001 변이주를 대상으로 균체생산 및 색소생성에 미치는 최적배양조건을 비교 검토하였다. 실험균주의 색소생성을 위한 액체배지의 최적화학적 조성은 4% rice powder, 0.15% Bacto-peptone, 0.1% glycine, 0.01% $FeSO_{4}{\cdot}7H_{2}O,\;0.1%\;MgSO_{4}{\cdot}7H_{2}O,\;0.25%\;KH_{2}PO_{4},\;pH4.5$였다. 실험균주의 $2.0{\times}10^{6}\;spores/ml$의 포자현탁액을 액체배지 50 ml에 접종하여 배양온도 $30^{\circ}C$에서 150 rpm으로 5일간 배양하였을 때, 10.00 g/L의 균체생산과 세포외 황색색소 오렌지색소와 적색색소는 각각 3.25 unit, 1.59 unit, 0.88 unit를 생성하였으며, 세포내 황색색소 오렌지색소와 적색색소는 84.96 unit, 78.84 unit, 91.80 unit의 색소를 생산할 수 있었다. The optimal conditions for Monascus pigments production of Monascus sp. KM 1001, pigment overproducing mutant, in submerged culture was investigated. The optimal medium for the production of pigment from KM 1001 mutant is determined to be composed of 4% rice powder, 0.15% Bacto-peptone, 0.1% glycine, 0.01% $FeSO_{4}{\cdot}7H_{2}O,\;0.1%\;MgSO_{4}{\cdot}7H_{2}O,\;0.25%\;KH_{2}PO_{4},\;pH4.5$. On optimal conditions,10.0 g/L of the cell mass was obtained at $30^{\circ}C$ for 5 days. Yellow, orange and red pigment of Monascus sp. KM 1001 were produced 3.25 units, 1.59 units and 0.88 units in extracellular part, and 84.96 units, 78.84 units and 91.80 units in intracellular part, respectively.

Interfraction Prostate Movement in Bone Alignment After Rectal Enema for Radiotherapy

서영은,김태효,이기수,조원열,이형식,허원주,최영민 대한비뇨의학회 2014 Investigative and Clinical Urology Vol.55 No.1

Purpose: To assess the effect of a rectal enema on interfraction prostate movement inbone alignment (BA) for prostate radiotherapy (RT), we analyzed the spatial differencein prostates in a bone-matched setup. Materials and Methods: We performed BA retrospectively with data from prostate cancerpatients who underwent image-guided RT (IGRT). The prostate was identified withimplanted fiducial markers. The setup for the IGRT was conducted with the matchingof three fiducial markers on RT planning computed tomography images and those ontwo oblique kV x-ray images. Offline BA was performed at the same position. The coordinatesof a virtual prostate in BA and a real prostate were obtained by use of theExaxTrac/NovalisBody system, and the distance between them was calculated as thespatial difference. Interfraction prostate displacement was drawn from the comparisonof the spatial differences. Results: A total of 15 patients with localized prostate cancer treated with curative hypofractionatedIGRT were enrolled. A total of 420 fractions were analyzed. The mean ofthe interfraction prostate displacements after BA was 3.12±2.00 mm (range, 0.20–10.53mm). The directional difference was profound in the anterior-posterior and supero-inferiordirections (2.14±1.73 mm and 1.97±1.44 mm, respectively) compared with theright-left direction (0.26±0.22 mm, p<0.05). The required margin around the clinicaltarget volume was 4.97 mm with the formula of van Herk et al. Conclusions: The interfraction prostate displacement was less frequent when a rectalenema was performed before the procedure. A rectal enema can be used to reduce interfractionprostate displacement and resulting clinical target volume-to-planning targetvolume margin.

The Efficacy and Safety of Tadalafil 5 mg Once Daily in the Treatment of Erectile Dysfunction After Robot-Assisted Laparoscopic Radical Prostatectomy: 1-Year Follow-up

서영은,김수동,김태효,성경탁 대한비뇨의학회 2014 Investigative and Clinical Urology Vol.55 No.2

Purpose: To evaluate the efficacy and safety of tadalafil 5 mg once daily use in the treatment of erectile dysfunction (ED) after robot-assisted laparoscopic radical prostatectomy (RALP). Materials and Methods: The study retrospectively evaluated 92 patients who underwent RALP at Dong-A University Hospital. The patients were surveyed by use of the abridged five-item version of the International Index of Erectile Function (IIEF-5) questionnaire, which was self-administered before surgery and at 6 months and 1 year after surgery. The 92 patients were classified into the tadalafil group (n=47) and the non-tadalafil group (n=45). Each group was then classified depending on the nerve-sparing (NS) procedure used: bilateral NS or unilateral NS. Results: At 6 months, the total IIEF-5 scores of the tadalafil group and the non-tadalafil group were 10.0±3.4 and 7.0±4.0, respectively. At 1 year, the total IIEF-5 score in the tadalafil group was significantly greater than that in the non-tadalafil group (13.2±5.6 vs. 7.7±4.8, p<0.0001). Statistically significant improvements (p<0.05) were observed in the tadalafil group for all 5 domains of the IIEF-5 score, whereas in the non-tadalafil group there was no significant improvement in any of the domains at 1 year. The reported side effects were flushing (8.5%, n=4), headache (4.3%, n=2), and dizziness (2.1%, n=1). Conclusions: In ED patients after NS RALP, a once-daily dose of tadalafil 5 mg was well tolerated and significantly improved EF compared with that in the non-tadalafil group.