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      • Z-DNA-ADAR1 단백질 복합체와 PNA:DNA hybrid에 대한 핵 자기 공명 연구

        서여진 경상대학교 대학원 2011 국내석사

        RANK : 247631

        Left-handed Z-DNA is in a higher energy conformation than right-handed B-DNA and forms in a polymer of alternating pyrimidine-purine nucleotides. The Zα domain of human ADAR1 (ZαADAR1) preferentially binds Z-DNA rather than B-DNA with high binding affinity. Two ZαADAR1 proteins bind to each strand of double-stranded DNA with 2-fold symmetry with respect to the helical axis. ZαADAR1 binds to the Z-conformation of both non-CG-repeat DNA duplexes and a d(CGCGCG)2 duplex similarly. In order to investigate the sequence effect on the DNA binding affinity and B-Z conversion activity of the ZαADAR1, we performed NMR experiments on complexes between the ZαADAR1 and non-CG-repeat DNA duplexes, d(CACGTG)2 or d(CGTACG)2, with a variety of protein-DNA molar ratios. Comparison of these results with those from the analysis of d(CGCGCG)2 in the previous study suggests that ZαADAR1 binds to Z-DNA via an active B-Z transition mechanism in which ZαADAR1 first binds to B-DNA and then converts it to left-handed Z-DNA that is stabilized by the binding of a second ZαADAR1 molecule. During the B-Z transition, ZαADAR1 exhibits the sequence preference of d(CGCGCG)2 >> d(CACGTG)2 > d(CGTACG)2 through multiple sequence discrimination steps. These results can explain how ZαADAR1 selectively recognizes the alternating d(CG)n sequence in a long genomic DNA.

      • 색채의 상징성을 통한 색채심리표현 지도방안

        서여진 경북대학교 대학원 2014 국내석사

        RANK : 247631

        Modern society experiences the surprising speed and changes of technology and information. We are connected with the communication through the technology, however we are suffered from the absence of communication. We also feel mentally confused and empty. Such mental state solves the mental trouble and problems of our own through the production of Mandara and helps to have new energy. Describing our actual state with colors and shapes it contributes to find the balance of life. In this way the color has an influence on one's feelings, emotion, comfort and uneasiness and it is able to check one's physical condition and cure it. For the positive development and mental health of human it is important to understand that the need for color education grows and the color has the signification. This study aims at making students have interest in color, understand its psychological effect and know that the color has the meaning through the symbolism of color. The study considers the signification in the symbolism of color and the psychological effect of the expression with color. And it considers the expression of color in terms of the stages of development according to the theory of Lowenfeld. Then the study compares the lessons for color in the art textbooks and analyzes them. Through the pre-examination about the color the study looks for ways to set the sections and ways to teach. Finally the study presents the lesson plan and applies it to the art-centered class in middle school. As a result choosing colors and making them helped students to understand the authentic meaning that the color gives. As the colors painted on the works revealed the inner thought the teacher could understand the students' psychology. Recognizing that the color represents the meaning made realize the importance of color. The result of this study let us have interest in things of life or nature and examine them. Then it let us think of the meaning of color associated with things or experience. Finding out the relationship between the color and the meaning the students who lack of self-confidence have the active attitude toward the life and this has a positive influence on the art education. There will be need to have the continuous interest and various teaching method in order not to focus on only one meaning of color.

      • 근로빈곤가구의 특성 및 결정요인에 관한 연구 : 2000-2008년 노동패널조사를 중심으로

        서여진 경북대학교 대학원 2011 국내석사

        RANK : 247631

        The purpose of this study is to examine characteristics and deciding factors of the working poor which covers the near poor. In order to do this, the working poor was classified into two groups - ‘the working poor’, 'the non-working poor'. Especially, the working poor was reclassified into two groups based on their long-term income: long-term income non-poverty group and long-term income poverty group. To accomplish the purpose, this study utilized the data provided by Korea Labor and Income Panel Study(KLIPS) from 2000 to 2008. The major results of this study can be summarized as the following. First, the 454 out of 1,395 working households experienced poverty during the 8-year-analysis. Among these households, 393 households and 61 households are classified into long-term income non-poverty and long-term income poverty groups. Second, the working households, which experienced poverty, were the lower human capital(female, the elder, low educational level), disadvantageous household characteristics(the spouseless, monthly rent, small number of household members, low labor income, low financial satisfaction), and unstable labor market status(simple labor, agriculture-fishery labor, occupational changes more than 2 times, temporary labor). Even in the working households, which experienced poverty, there were different characteristics between long-term income non-poverty and long-term income poverty groups. Third, according to the important factors deciding whether to have experienced poverty or not, it is more likely to experience the working poor status if they have such characteristics as demographical characteristics(female, age-in their 40's, lower than middle-school-educational level), household characteristics(the spouseless, larger family), and labor market characteristics(occupational changes more than 2 times, non-full-time workers). Based on the results of this study, research implications are as follows. The policies for the working poor need to improve the current policy focusing on creating merely temporary works. Moreover, they need to create decent jobs to guarantee stable income and take prior attentions to the socially weak such as the female, and the spouseless, and so on.

      • External environmental migration as an adaptation strategy

        서여진 Graduate School, Yonsei University 2020 국내석사

        RANK : 247615

        The term climate refugees (or environmental refugees) has been gaining currency as a normative and sociological term. So far legal advocates and practitioners have encountered difficulties in assisting individuals who claim they fit within this term, as the term has yet to become de jure in national legal systems. However, when analyzing vulnerable regions such as small island states, the salience of the term has rather rendered climate refugees a de facto concept. The aim of this study is to examine whether the notion of climate refugees should be expected to gain legal and moral recognition within nation-states. First, the study argues that at the systemic level, the current refugee and environmental regimes are unable to fully support the notion of climate refugees, thus I analyze whether climate refugees could exist at a local or regional level. Therefore, by taking a case study on the Pacific Region, I address whether state initiatives could help lend validity to such a term. The aim of this study is to indicate that states may play a pivotal role that is supportive of climate refugees, but when taking into consideration the crisis and failures of the refugee regime, I analyze that the usage of the term migrants rather than the term refugees has the greater potential of delivering climate justice. Likewise, the study suggests that the term ‘external environmental migrant’ would be a more suitable term as migration might play a pivotal role than the existing ‘durable solutions’ found within the refugee regime. 기후 난민(또는 환경 난민)이라는 용어는 규범적이고 사회학적인 용어로 통용되고 있다. 지금까지 법치부의자들과 실무자들은 이 용어가 아직 국가 법률 시스템에(de jure) 존재하지 않았기 때문에 그 동안 환경난민이라고 주장하는 개인들을 돕는 데 어려움을 겪어왔다. 군소 도서 국가(small island states)와 같은 취약한 지역을 분석할 때, 그 용어의 명료함(salience)은 기후 난민을 사실상의 개념으로 만들었다고 평가받는다. 그러므로 이 연구의 목적은 기후 난민에 대한 개념이 국가 내에서 법적, 도덕적 인정을 받아야만 하는지를 조사하는 것이다. 먼저, 이 연구는 제도적(systematic) 차원에서 현행 난민과 환경레짐(regime)이 기후난민의 개념을 전 세계적인 규모에서 총체적으로 보여줄 수 없기 때문에 기후난민이 지역적(regional and local) 차원에서 존재할 수 있는지를 분석하고자 한다. 따라서, 태평양(Pacific) 지역에 대한 사례 연구를 함으로써, 국가 수준의 환경난민문제에 대한 전폭적인 언급 밑 선전 행위가 그러한 용어에 타당성을 부여하는 데 도움이 될 수 있는지 여부를 다루고자 한다. 이 연구의 목적은 국가가 기후 난민을 지지하는 중추적인 역할을 할 수 있음을 나타내는 것이지만, 난민레짐의 위기와 실패를 고려할 때, 난민이라는 용어보다 이주민이라는 용어의 사용이 향후 기후 정의를 전달할 수 있는 더 큰 잠재력을 가지고 있다고 분석한다. 이와같이, 이 연구는 '초국가적(또는 외부)-환경-이주자'라는 용어가 난민 레짐 내에서 발견되는 기존의 '지속가능한 해결책(durable solutions)'보다 더 적절한 용어일 것임을 제안한다.

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