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RISS 인기검색어
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- 저자 : 서상준(Sang Joon Suh) (검색결과 28 건)
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서상준 ( Sang Jun Suh ),임형준 ( Hyung Joon Yim ),이동원 ( Dong Won Lee ),현종진 ( Jong Jin Hyun ),정영걸 ( Young Kul Jung ),김지훈 ( Ji Hoon Kim ),서연석 ( Yeon Seok Seo ),연종은 ( Jong Eun Yeon ),변관수 ( Kwan Soo Byun ),엄순호 대한간암학회 2017 대한간암학회지 Vol.17 No.1
Background/Aims: Hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT) exhibits poor prognosis. The aim of this study is to evaluate factors associated with survival of HCC patients with PVTT to suggest better therapeutic options. Methods: Patients with HCC which were newly diagnosed at three tertiary hospitals between January 2004 and December 2012, were reviewed retrospectively. Among them, Barcelona Clinic of Liver Cancer stage C patients with PVTT were identified. Factors affecting overall survival (OS) were analyzed and efficacies of the treatment modalities were compared. Results: Four hundred sixty five patients with HCC and PVTT were included. Liver function, tumor burden, presence of extrahepatic tumor, alfa fetoprotein, and treatment modalities were significant factors associated with OS. Treatment outcomes were different according to the initial modalities. OS of the patients who received hepatic resection, radiofrequency ablation (RFA), transarterial chemoembolization (TACE), hepatic arterial infusion chemotherapy (HAIC), sorafenib, systemic cytotoxic chemotherapy, radiation therapy (without combination), and supportive care were 27.8, 7.1, 6.7, 5.3, 2.5, 3.0, 1.8, and 0.9 months, respectively (P<0.001). Curative-intent treatments such as hepatic resection or RFA were superior to noncurative-intent treatments (P<0.001). TACE or HAIC was superior to sorafenib or systemic chemotherapy (P<0.001). Combining radiotherapy to TACE or HAIC did not provide additional benefit on OS (P=0.096). Conclusions: Treatment modalities as well as baseline factors significantly influenced on OS of HCC patients with PVTT. Whenever possible, curative intent treatments should be preferentially considered. If unable, locoregional therapy would be a better choice than systemic therapy in HCC patients with PVTT. (J Liver Cancer 2017;17:60-71)
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서상준,조문재,김련수,Suh, Sang-Joon,Jho, Moon-Jae,Kim, Youn-Soo 한국음향학회 1989 韓國音響學會誌 Vol.8 No.1
建策材料의 複素反射係數로 測定하기 爲해 새로운 方法을 指示하였다. 旣存의 方法인 正常波管內에서 正常波比를 測定하여 反射係數를 計算할 境遇, 管內에서 音壓의 最大값과 最小값을 精密하게 測定하기 爲해서는 많은 努力을 기울여야 하면 特히 많은 試料를 取扱할 때 境過 매우 번거로운 作業이 된다. 本 論文에서는 이러한 短點을 補完하기 爲해 任意의 세 位置에서 音壓과 位相 및 各 測定점까지의 距離를 測定한 後 最小自乘法에 의해 複素反射係數를 測定하는 方法을 考案하였다. 이 方法으로 두께 5cm, 密度 $50kg/m^3$인 유리纖維와 두께 1.5cm 인 鋼부反에 대한 複素反射係數를 測定한 結果와 旣存의 方法으로 測定한 結果가 잘 一致하는 것을 實驗으로 確認하였다. 또한 이 方法은 길이가 짧은 正常波管으로도 低周波의 反射係數를 測定할 수 있는 長點이 있을 뿐만 아니라 컴퓨터와 interface가 가능하기 때문에 특히 試料를 取扱하는 境遇 效果的으로 使用될 수 있을 것을 期待된다. The reflection coefficients of the sound absorbing materials are obtained from the standing wave ratio in the standin wave tube. This method is rather laborious to find the sound pressure maximum and minimum. We devised new method for determination of the complex reflection coefficients of the materials. The sound pressures and the phases are measured at least three points along the axis of the tube. The complex reflection coefficients are determined from the measured values by least square method. The measured results for the glasswool with thickness of 5cm and density of $50kg/m^3$ and the steel plate with thickness of 1.5cm are in good agreement with those of the conventional method. It is possible to measure the complex reflection coefficients at low frequencies with short standing wave tube and to interface with the personal computer which is very useful for the handling of amount of samples.
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가역원리에 의한 1인치 표준 컨덴서 마이크로폰의 정밀교정
서상준,조문재,Suh Sang Joon,Moon Jae Jho 한국음향학회 1989 韓國音響學會誌 Vol.8 No.5
표준 컨덴서 마이크로폰의 정밀 교정은 가역원리를 이용한 가역교정에 의해 이루어진다. 본 연구에서는 가역교정 중에서도 결합기를 이용하는 음압교정(pressure calibration)을 수행하여 세 개의 1인치 컨덴서 마이크로폰의 음압감도를 결정하였다. 마이크로본의 음압감도를 정밀하게 결정하기 위해서는 전압이나 결합기의 치수를 정밀하게 측정하여야 하며 결합기의 구조상 발생하는 제반 현상들에 대한 보정을 정확하게 해 주어야 한다. 이와같은 사항들을 정화하게 고려할 경우 가역교정에 의한 교정정밀도는 저주파와 중간 주파수 영역에서 0.05dB이며 10kHz 이상에서는 0.ldB가 된다. The calibration of 1 inch standard condenser microphone is done by the reciprocity calibration method. There are two kinds of reciprocity calibration, free-field calibration and pressure calibration. The pressure sensitivities of the three 1 inch condenser microphones are determined by pressure calibration. The accuracy of the pressure sensitivity of the microphone depends on the accuracies of the voltage and dimension measurements as well as the various corrections for the coupler. If the individual accuracies for the measurements and corrections are achieved, it is estimated that the over-all accuracy is approximately 0.05dB at low and middle frequencies decreasing to about 0.ldB over 10kHz.
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서상준 ( Sang Jun Suh ),임형준 ( Hyung Joon Yim ) 대한소화기학회 2013 대한소화기학회지 Vol.61 No.3
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer death in Korea. Curative treatment is only possible when the disease is diagnosed at the early stage. The prognosis of patients with HCC is even dismal in advanced stages. No systemic cytotoxic chemotherapy has proven to be beneficial in overall survival. Recently, the understanding of the molecular pathogenesis led to the development of new therapies. With the evidence of dysregulation of critical genes associated with cellular proliferation, growth factor signaling, cell cycling, apoptosis, and angiogenesis in HCC, a number of molecular target agents are under clinical trials. Sorafenib is the first systemic anticancer drug which has proven to gain survival benefit in the global as well as Asia-Pacific trials. However, the survival gain is still modest, and further efforts to improve outcomes in patients with HCC are necessary by developing novel drugs or combining other forms of therapies. This article will review signaling pathways in HCC and introduce molecular target agents under investigation currently. (Korean J Gastroenterol 2013;61:136-146)
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서재갑,서상준,Suh, Jae-Gap,Suh, Sang-Joon 한국음향학회 2007 韓國音響學會誌 Vol.26 No.8
A reverberation chamber should be designed and constructed so as to satisfy its purposes and available space. However, it is somewhat difficult to meet the intended design requirements due to various errors from construction process. So, the post-construction measurement of its volume and surface areas is very essential to check the actual volume and volume uncertainty of a reverberation chamber These values should be carefully calculated and accurately estimated since they are used not only to evaluate the acoustic characteristics of building materials but also to calculate uncertainties for other acoustic characteristics. In this work, the method for the calculation and uncertainty estimation of the volume of a reverberation chamber is presented. To this end, the coordinates of all corners was measured with Total Station after construction. The results showed that the calculated volume of the measured reverberation chamber differs by 5 % from the design specification. The expanded volume uncertainty was also estimated to be about 2 % of the total calculated volume. 잔향실은 사용 목적과 주어진 공간에 따라 적절한 크기와 형태를 갖도록 설계, 시공된다. 그러나 일반 공작물과는 달리 정확한 설계도에 따른 시공이 어렵기 때문에 완공후에는 실제 치수를 측정하여 체적과 표면적 등을 확인하는 것이 중요하다. 이러한 값들은 잔향실을 이용하여 측정하는 건축재료의 음향특성 계산에 직접 사용될 뿐만 아니라 체적 불확도는 음향특성의 불확도 산출에도 중요한 요소이기 때문에 정확하게 계산하여야 한다. 본 논문에서는 잔향실 완공 후, Total Station으로 각 꼭지점의 좌표를 측정하여 이로부터 잔향실의 체적과 불확도를 산출하는 방법을 제시하였다. 잔향실의 체적을 계산한 결과 설계값과 약 5 %의 차이가 나는것을 확인할 수 있었으며, 잔향실 체적의 확장불확도를 평가한 결과 전체 체적의 약 2 %정도인 것을 확인하였다.
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윤기상,서상준,서재갑,Yoon, Ki-Sang,Suh, Sang-Joon,Suh, Jae-Gap 한국음향학회 2007 韓國音響學會誌 Vol.26 No.1
본 논문에서는 여름철마다 소음으로 사회적인 문제가 되고 있는 말매미 노랫소리의 음향특성과 발음 메커니즘을 연구하였다. 자연 상태에서의 노랫소리를 대상으로 파형과 FFT를 분석하였으며, 고속사진촬영으로 진동막 운동 형태를 분석하였다. 수컷 말매미의 복부 공동 (Cavity)의 공진주파수를 알기 위해 강제 공진 실험을 실시하였다. 실험 결과, 말매미의 두 진동막은 시간적으로나 형태적으로 비대칭 운동을 하며 매 진동시마다 다양한 주파수가 발생하는 것으로 관찰되었다. 또한 말매미는 약 $7{\sim}7.5 kHz$ 영역의 소리를 공명시킬 수 있는 구조를 갖는 것으로 확인되었다. This paper presents a study on acoustic characteristics and sound generation mechanism of Cryptotympana atratas' songs which cause noise problems in summer days. The waveforms & FFT of Cryptotympana atratas' songs in nature were analyzed, and the actions of tymbals were visualized by the high speed camera. In order to know resonance frequency of the abdominal cavity of male Cryptotympana atrata, the sine sweep test was done. It was observed from the experimental results that Cryptotympana atrata's two tymbals act asymmetrically with respect to time & shape, and make a variety of frequencies every time it vibrates. It was also shown that Cryptotympana atratas' have a structure that cause resonances sounds only in a $7{\sim}7.5 kHz$ bandwidth.
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