중남미에 처음으로 전해진 스페인어 형태 연구

서경석(Kyung-Suk Seo) 한국라틴아메리카학회 2003 라틴아메리카연구 Vol.16 No.1

수목장의 도입을 통한 산림의 효율적 활용방안에 관한연구

서경석(Seo Kyung-Suk),김갑열(Kim Gab-Youl) 한국주거환경학회 2006 주거환경(한국주거환경학회논문집) Vol.4 No.1

  The aim of this study is to show the reform of burial culture through the new burial system which is called by the woodland burial. the effective use of the country land and the economical and practical plan including forest conservation and tending policy which are valued with it.<BR>  As the method of this study, the meaning and the characteristic of the woodland burial were examined at first, and then this study analyzed the percentage of cremation and the present using state of the burial facilities, the valuation basis by the function of the common benefits and the efficient use of economy through the data of statistics and the precedent researches.<BR>  And this study showed the promoting facts to introduce and stabilize the woodland burial through the analysis about effect of the present burial culture.<BR>  management method, it can be ended in a short time and be gone off the idea which defend to change the forest mountain into the burial ground.<BR>  Therefore the system of the woodland burial should be needed the cautious approach.<BR>  Finally the movement and campaign should be begun to spread outcontinuously in future. with considering that 47.2% of Korean want to use the woodland burial by the recent survey which is the recognition survey about the woodland burial.

An imported case of hepatic unilocular hydatid disease

채종일,서민,서경석,이순형,CHAI, Jong-Yil,SEO, Min,SUH, Kyung-Suk,LEE, Soon-Hyung The Korean Society for Parasitology 1995 The Korean Journal of Parasitology Vol.33 No.2

소화불량을 주소로 내원한 38세 남자의 초음파 촬영과 전산화단층촬영 소견에서 간의 낭종이 발 견되어 낭종적출술을 시행하였다. 낭종은 성공적으로 적출되었으며, 현미경 하에서 낭액 내에 살아 움직이는 단방조충(Echinococcus granulosus)의 protoscolek가 다수 관찰되었다. 그러나, 수술중 낭종이 터져 낭액의 유출이 있었다. 술후 환자는 albendazole을 투약받았으며, 아나필락시스 등 합병증은 관찰되지 않았다 환자는 1982년부터 3년간 사우디아라비아에서 근무한 적이 있었다. 이 환자는 국내에서 확진된 단방포충 낭종증의 제16례로, 수술 중 낭종이 터졌으나 아나필락시스를 일으키지 않은 1례이었다. A 38-year old man visited a private clinic complaining of epigastric discomfort for 2 months A huge hepatic cyst was found by sonography and computerized tomography. An exploratory Laparotomy was performed under the impression of hydatid disease. The cyst was successfully removed. A lot of living protoscolices of Echinocucur Sranulosus were found from the cystic fluid under light microscopy. During the operation, however. the cyst was accidentally ruptured and the cystic fluid spilled out. The patient was medicated with albendazole, and had been well without any signs of anaphylaxis or recurrence for 1 year follow-up period. He had been in Saudi Arabia for 3 years. This is the 16th case of hydatid disease reported in Korea and a case without immediate complication in spite of rupture of the cyst.

생체 부분간이식이 시행된 Hepatic Epithelioid Hemangioendothelioma 증례

서형일(Hyung-Il Seo),박상재(Sang-Jae Park),김성훈(Seong Hoon Kim),서경석(Kyung-Suk Suh),이남준(Nam-Joon Yi),이우진(Woo Jin Lee),최준일(Joon Il Choi),이순애(Soon-Ae Lee),홍은경(Eun Kyung Hong),박중원(Joong-Won Park),김창민(Chang-Min K 한국간담췌외과학회 2006 한국간담췌외과학회지 Vol.10 No.3

간 이식 소아에서 발생한 이식 후 림프 증식 질환: 단일 기관에서의 21년 경험

이정화,고재성,서정기,이남준,서경석,이건욱,강경훈,Lee, Jung-Hwa,Ko, Jae-Sung,Seo, Jeong-Kee,Yi, Nam-Joon,Suh, Kyung-Suk,Lee, Kuhn-Uk,Kang, Gyeong-Hoon 대한소아소화기영양학회 2009 Pediatric gastroenterology, hepatology & nutrition Vol.12 No.2

Purpose: To analyze the clinical spectrum of posttransplantation lymphoproliferative disorder (PTLD) after liver transplantation in children. Methods: From January 1988 to June 2009, we retrospectively reviewed the medical records of 8 PTLD cases among 148 pediatric patients underwent liver transplantation. The age at transplantation, time of presentation after transplantation, clinical manifestations, histologic diagnosis, results of EBV (Epstein-Barr virus) assessments, managements and outcomes of PTLD were investigated. Results: The prevalence of PTLD in liver transplant pediatric recipients was 5.4% (8 of 148). The mean age of patients was 25.4${\pm}$21.3 months (range 10 to 67 months). Seven of 8 patients (87.5%) underwent liver transplantation before 1 year of age. The common clinical presentations were persistent fever (8 of 8, 100%) and bloody diarrhea (6 of 8, 75%). PTLD was diagnosed with gastrointestinal endoscopic biopsies in five patients and surgical biopsies in three. Histologic findings showed early lesion in three patients, polymorphic in two, and monomorphic in three. Burkitt lymphoma and lymphoblastic lymphoma were found in two of 3 monomorphic patients. Seven of 8 patients were found with EBV-positive. Eight patients were treated with dose reduction of immunosuppressants and infusion of ganciclovir. Rituximab was added to four patients. PTLD were successfully managed in all patients except one who died of sepsis during chemotherapy. Conclusion: Major risk factor of PTLD was to undergo liver transplantation before 1 year of age. Continuous monitoring for EBV viral load and gastrointestinal endoscopic biopsy may be useful to early detection of PTLD. 목 적: 간 이식 소아에서 발생한 PTLD의 경험을 통해 발현 양상, 발병 위험 인자, 진단 방법, 치료 및 예후에 영향을 줄 수 있는 요인들을 알아보았다. 방 법: 1988년 1월부터 2009년 6월까지 서울대학교 어린이병원에서 간 이식을 받은 소아 148명 중 PTLD로 진단된 8명의 환아들을 대상으로 후향적 분석을 하였다. 이식당시 나이, 이식 후 PTLD 증상이 나타날 때 까지의 기간, 임상적 증상, 조직학적 소견, EBV 검사 결과, 치료 및 경과에 대해 조사하였다. 결 과: 간 이식 후 PTLD의 유병률은 5.4%였고, 발생시기는 조기 PTLD가 6명(75%), 후기 PTLD가 2명(25%)이었다. 대상 환아의 간 이식 당시 나이는 평균8.1${\pm}$4.4개월로, 12개월 미만이 7명(87.5%), 12개월 이후가 1명(12.5%)이었다. PTLD 진단 시 주증상은 발열, 설사, 혈변이었고 모두 장이나 장간막 림프절 침범이 있었다. 3명은 개복 수술로 5명은 상부 위장관 내시경이나 대장 내시경을 통한 조직 검사로 진단되었다. 조직학적 진단은 early lesion이 3명, polymorphic PTLD 2명, monomorphic PTLD 1명, Burkitt 림프종 1명, B 세포 림프종이 1명이었다. EBV는 7명에서 양성을 보였다. 치료는 전례에서 1차 치료로 면역억제제를 중지하고 항바이러스제(ganciclovir)를 투여 하였다. 4명의 환아들에서 rituximab을 추가하였고 Burkitt 림프종과 B 세포림프종으로 진단된 환아들은 각각 항암 치료를 병행하였다. B 세포 림프종으로 진단되어 치료 중에 패혈증으로 1명이 사망하였으며 나머지 7명은 호전되었다. 결 론: 1세 미만에 간 이식을 받은 경우가 PTLD 발생의 주요한 위험 인자였으며, EBV viral load의 지속적인 감시와 위장관 내시경을 통한 조직 검사가 PTLD 조기진단에 유용할 것으로 생각한다.

원발성 경화성 담도염에 대한 간이식 1예 보고

김수태(Soo Tae Kim),이건욱(Kuhn Uk Lee),김상준(Sang Joon Kim),김선희(Sun Whe Kim),서경석(Kyung Suk Seo),윤용범(Yong Bum Yun),이국현(Kuk Hyeun Lee),하종원(Jong Won Ha),박연호(Yeoun Ho Park) 대한외과학회 1995 Annals of Surgical Treatment and Research Vol.49 No.3

개에서 자가 부분 간 이식술전후 동맥혈의 KBR ( Ketone Body Ratio ) 측정과 이식 간의 초기 기능부전 지표로서의 상관관계에 관한 연구

김상준(Sang Joon Kim),김수태(soo Tae Kim),안세현(Sei Hyun Ahn),김병식(Byung Sik Kim),정중기(Jung Kee Jung),김건표(Kyun Pyo Kim),서경석(Kyung Suk Seo) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.5

N/A Living-related segmental liver transplantation is now accepted as a method of liver transplantatior in pediatric group. But if graft failure occurs, mortality is high. Hence the early prediction of graft failure may contribute to the improvement of the chance of survival. The ketone bodies (acetoacetate, B-hydroxybutyrate) are known to be produced in the hepatic mitochondria. KBR (ketone body ratio) is a ratio of acetoacetate/B-hydroxybutyrate, which ref1ects the NAD+/NADH, i.e. oxidoreduction state of NAD of hepatic mitochondria. Because the viability of grafted liver is ultimately depeadant on the oxidoreduction potential of hepatic mitochondria, KBR might reflect the viability of grafted liver. The purpose of this experiment is to study whether KBR is a useful indicator of initial grat failure after liver transplantation. The experiment consisted of ten autologous left lobe liver transplants in dogs. The arterial blood was taken at preoperative period, anhepatic stage, reperfusion-15 minutes, 1 hour, 3 hour, 6 hour anl daily during their survival, and then KBR was calculated by ketone body concentration. The result of KBR measurement was as follows; it was 1.16+-0.33 at preoperative period, and abruptly decreased to 0.46+- 0.21 at anhepatic stage, and recovered to various levels according to initial graft function after reperfusion. To evaluate the initial graft function, the dogs were divided into two groups. A group (n=3) had KBR below 0.7 at reperfusion 1 hour, and B group (n=7) above 1.0. In group A, all of them showed early graft failure and died within 12 hours postoperatively. KBR changes in group A were as follows; it was 1.16 at preoperative period, and decreased to 0.25 at anhepatic stage, and recorded 0.69, 0.54, 0.61, 0.29 at reperfusion-15 min, 1 hour, 3 hour, 6 hour respectively. It never recovered above 0.7 at any period after reperfusion. In group B. they showed good early-graft function with survival of 16 hours to 8 days and died of other causes, ln group B, preoperative KBR was 1.16, and decreased to 0.54 at anhepatic stage, but promptly recovered to 0.95 at reperfusion-15 minute, 1.32 at 1 hour. It slightly decreased to 0.83 at 1 hour but maintained above 1.0 after 6 hour. In conclusion, the decreased KBR at anhepatic stage should promptly recover after reperfusion for the graft viability, and the value below 0.7 of KBR after reperfusion-1 hour represents the early graft failure, and above 1.0 of KBR represents good functioning graft. The KBR is a useful indicator of early graft function in canine autologous segmental liver transplantation, and it is assumed that KBR is further applicable on canine and human allogenic segmental liver transplantation.