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Pressure-induced Resonance Raman Effect of InAsxP1−x Alloy Films on InP
변준석,김영동,박타령 한국물리학회 2012 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.61 No.10
We have studied the effect of hydrostatic pressure on the Raman spectra of the InAs<I><SUB>x</SUB></I>P<SUB>1-<I>x</I></SUB> alloy films that were grown on InP substrates. The high-pressure Raman scattering provides very useful information on the microscopic properties of the materials because electronic transition can be controlled by the pressure. The samples with intermediate compositions (0 < x < 1) exhibit both InAs-like and InP-like mode at all the pressures (up to ~80 kbar) we tried. It is well known that pressure increases the magnitude of E1 band gap whose magnitude is responsible for the Raman scattering efficiency of the related materials such as InP and GenSim multiple quantum wells. Using 457.9 nm (2.708 eV) line of argon ion laser we could observe enhanced Raman scattering efficiency for the three x = 0.7, x = 0.75, and x = 0.8 alloys at certain pressures, which indicates that the three samples have E1 band gap below 2.708 eV at ambient pressure. (Notice that both InAs-like and InP-like mode show resonance features). This result is consistent with the measurement of the electronic structure by ellipsometry. The shift-rates of E1 band gap of the three samples are comparable to that of InP. The resonance of ternary alloys with wider widths than InAs indicates that they have spatially fluctuating E1 band gaps, although good electronic band structures are maintained.
Usefulness of for BI-RAD Category 4 or Higher Lesions
변준석,오현화,이혜윤,김금원,김진숙,윤대성 대한종양외과학회 2017 Korean Journal of Clinical Oncology Vol.13 No.1
Purpose: As an alternative to core-needle biopsy in confirming the diagnosis of breast cancer, the usefulness of 99mTc-sestamibi scintimammography (MIBI scan) has been rarely reported. Thus, we aimed to evaluate a direct comparison between general diagnostic modalities and breast MIBI scan, which may be revealed as a potential diagnostic alternative. Methods: In a retrospective study, 301 patients with 801 lesions, who underwent breast MIBI scan, ultrasonography, and mammography simultaneously between January 2013 and February 2015, were reviewed. All data were analyzed by McNemar and Kappa test for statistical significance. Results: Mean age was 49.2±9.37 years old (range from 26 to 85 years old). Results of Breast MIBI scan were divided into three categories: 236 positive intensity uptakes (29.5%), 565 negative intensity uptakes (70.5%), and 67 suspicious abnormal intensity uptakes (8.4%). Pathologic reports were also allocated into four subgroups: 122 invasive cancers (15.2%), 44 non-invasive cancers (5.5%), 194 proliferative benign lesions (24.2%), and 441 non-proliferative benign lesions (55.1%). The sensitivity, specificity, positive predictive value, and negative predictive value of MIBI scan were 83.5%, 55.6%, 59.1%, and 95.2%, respectively. Specificity of MIBI scan plus general diagnostic modalities increased dramatically, up to 85.2%, compared to general modalities (6.8%). Conclusion: In general diagnostic modalities, such as mammography and ultrasound, BI-RAD category 4 or higher lesions were performed by needle biopsy rather than observation. The outstanding specificity and negative predictive value of MIBI scan provided confident results on non-proliferative benign lesions. MIBI scan may offer an alternative diagnostic tool for “invasive” biopsy procedures.