Effect of Facial Parameters on the Incidence of Rejection and Artifacts on the Video Head Impulse Test

변광현,류혜수,정재윤,최지은,이민영 대한이비인후과학회 부산,울산,경남 지부회 2021 임상이비인후과 Vol.32 No.2

Background and Objectives: The video head impulse test (vHIT) is a useful tool that uses a high-speed infrared video camera and an inertial accelerometer to quantify the vestibulo-ocular reflex. Despite advancements in recording technology, physicians should be aware of measurement artifacts induced by examiners. However, little is known about the impact of facial anatomy on artifacts. Therefore, we investigated how variance in facial anatomy affects measurement artifacts. Materials and Methods: This study enrolled nine subjects from November 2018 through November 2019. A digital camera was used to measure facial parameters, including head ratio, binocular spacing, nasofrontal angle, depth of nasion, and pupil ratio. Two examiners performed vHITs with ICS Impulse System (GN Otometrics). All impulses were assessed for artifacts, including rejection, notch during head impulse (notchduring), notch after head impulse (notchafter), and rebound. Results: The rejection rate was significantly correlated with depth of nasion, as measured by the experienced examiner, and with pupil ratio, as measured by the inexperienced examiner. notchduring rate was significantly correlated with nasofrontal angle, as measured by the inexperienced examiner. Rebound rate was significantly correlated with head ratio, as measured by both examiners. Conclusions: Measurement artifacts were significantly correlated with head ratio, depth of nasion, nasofrontal angle, and pupil ratio.

岩刻畵 拓本에 대한 技法 硏究

변광현 安東大學 1997 安東大學 論文集 Vol.19 No.1

"Takbon" in Korean means a copy made from tapping on the paper with ink pad("Mung-chi" in Korean, says like "moong-czhee"). It also means a rubbed copy of petroglyphs or pictographs of tombstone or stone monuments. The techniques of "Takbon" come from that of the traditional woodcut print, which is at first, brushed the ink onto the engraved or cut-in wood panel with ink brush("Muk-Sol"), and then covered the paper, and rubbed in circles on the surface of paper with the wad of human hair or horse's mane, which were called "Inczhe´" and "Maryop" in Korea in the past, and also "Baren" as a disc pad be covered with a bamboo shoot in Japan. "Bazi" with horsehair and "zongpica" with the fiber filament of palm tree in china. But because of techniques of wood cut should stain the wood or any object with the ink, it must be apllied differently to keep the surface of rocks in petroglyphs as be good. I mainly refered to the basic method written in the book, "The world of Takbon"(Ilzisa, 1991), which was written by a buddhist monk "Byongzin" who is the "Takbon" specialist in Korea. I have improved and applied his genius unique tool(ink pad) and techniques of "Takbon" from ancient weathered rocks thorough having in practice at 6 of places in petroglyphs scattered in southern korea ; chilpori in yongil, sokjangdong in kyongju, bosongri in yongchon, anhwan in koryong, tekokri in namwon, dohangri in haman. "Takbon" is the method of defining the figures of engraved petroglyphs which are dim and vague by weathering or moss. But surface of rocks is rough, sunk and mixed with the deep cracks, so you have got to press with a small "Mungchi" in the narrow surface sometimes. You look at the figures of it subjectively, and find out the figure and press with "Mungchi" by the design in your mind. Because of the figures made from your mind and can not press with a large plain "Mungchi" such as the press machine, takbon is absolutely not a copy of object, become art works such as monoprints in printmaking or even paintings.

상악동 진균구의 범위에 따른 수술 후 결과 차이

주여림,변광현,안정현,최기용,모지훈,정영준 대한이비인후과학회 2021 대한이비인후과학회지 두경부외과학 Vol.64 No.1

Background and Objectives Fungus ball is the most common type of fungal sinusitis commonlyassociated with good prognosis. However, postoperative results depending on the extentof the lesion has not been investigated. This study aimed to identify differences in postoperativeresults depending on the location and extent of the fungus ball. Subjects and Method Medical records of 165 patients who underwent endoscopic sinussurgery and who were diagnosed with fungus balls by biopsy from 2010 to 2019 were retrospectivelyreviewed. Patients were classified into four grades according to the location and extentof the fungus ball based on their endoscopic and CT findings. Poor outcome is defined asany pathologic signs such as nasal secretion, granulation, and polyps or narrowing of the naturalostium observed postoperatively according to Kennedy’s criteria, whereas good outcomeis defined as absence of pathologic signs. Results A total of 23 patients were Grade 1, 38 Grade 2, 67 Grade 3, and 37 Grade 4. Grades1 and 2 were mostly asymptomatic. However, as the location of the fungus ball became closerto the natural ostium, patients complained postnasal drip and purulent discharge. Grades 3 and4, who have much severe and more extensive lesions than those of Grades 1 and 2, had pooroutcome (p=0.007) and took longer time to completely recover (p<0.001). Conclusion Wound healing was delayed and poor when the fungus ball was located closer tothe natural ostium of the maxillary sinus. Therefore, preoperative consultation using endoscopicand CT findings could be useful for predicting their postoperative results.

Screening of A1555G mDNA Variant Using U-TOP™HL Genotyping Kit in Korean Family with Progressive Hearing Loss

안정현,변광현,정보경,이민영 대한이비인후과학회 2021 대한이비인후과학회지 두경부외과학 Vol.64 No.2

Recently, real-time polymerase chain reaction (PCR) using the U-TOP™HL Genotyping Kithas been introduced to detect genetic hearing loss caused by certain type of gene variantspopularly found in Korea. The mitochondrial 12S ribosomal ribonucleic acid (rRNA) genesare related to aminoglycoside induced or non-syndromic, sensorineural hearing loss. Amongthem, 1555A>G is commonly found and reported worldwide. We are presenting the case of amother and a son, who were screened by real-time PCR using the U-TOP™HL GenotypingKit and were found both to have the mitochondrial 12s rRNA 1555A>G variant with a differenthearing loss phenotype. This report encourages clinicians to use this or similar screenmethods for patients with familial hearing loss.

비용종을 동반한 만성 비부비동염의 내재형(endotype)에 따른 임상상과염색 방법에 따른 호중구성 비용종의 분류와 임상적 특징

김효연,모지훈,유신혁,변광현 대한이비인후과학회 2024 대한이비인후과학회지 두경부외과학 Vol.67 No.2

Background and Objectives There are various methods used to histologically assess thecell count of neutrophils in nasal polyps. With various classification of neutrophilic nasal pol-yps, determining the appropriate staining techniques and criteria is deemed important for thediagnosis of neutrophilic nasal polyps by assessing neutrophil cell counts. In this study, wetried to optimize different methods of neutrophil counting and staining by comparing clinicaloutcomes. Subjects and Method We studied 207 patients who underwent endoscopic sinus surgeryfor chronic rhinosinusitis with nasal polyp from August 2014 to September 2018. Patients’ na-sal polyp were taken to make following three slide sections: hematoxylin and eosin, humanneutrophil elastase (HNE), myeloperoxidase. After staining, microscope picture (×400) wastaken and neutrophils were counted. Neutrophil polyp (NP) was classified either by the tissueneutrophil count (20/HPF) or by the neutrophil percentage (1%/total cell) for clinical outcomecomparison. Results Two groups were made after HNE staining: the NP and the non-NP groups. TheL-K scores and delta showed significant differences between each group while neutrophil wasdefined based on 20 counts/HPF ( p<0.001). By Kaplan-Meier estimation, there was no statis-tical meaning between the two groups. But the NP group had a tendency to recur more thanthe non-NP group while 20 counts/HPF definition was used ( p>0.05). Conclusion HNE staining and 20 counts/HPF were the most specific for neutrophil count-ing. Analyzing the nasal polyp into two groups due to histologic types showed that the NPgroup had worse prognosis than the non-NP group. In conclusion, neutrophils in the nasal pol-yp might be considered seriously for clinical outcomes.