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복강경 담낭절제술에서 수술 전 자기공명췌담관조영술의 유용성
백진오,김용훈,안근수,박태준,강구정,임태진 대한내시경복강경외과학회 2012 Journal of Minimally Invasive Surgery Vol.15 No.3
Purpose: The aim of this study is to evaluate the value of preoperative MRCP prior to laparoscopic cholecystectomy by analysis of postoperative outcomes. Methods: Between 2009.12∼2010.12, 283 patients underwent laparoscopic cholecystectomy for treatment of benign biliary disease. Among these patients, 125 underwent preoperative MRCP and were classified as the MRCP group. The remaining 158 patients who did not undergo MRCP were classified as the non MRCP group. We compared perioperative data,including the rate of bile duct injury, operative complication,conversion rate, hospital stay, and hospital cost between the two groups. In addition, we analyzed preoperative MRCP findings,including common bile duct (CBD) stones and bile duct anomaly. Results: Findings on pre-operative MRCP scan revealed silent CBD stones in five patients (4.0%) and bile duct anomalies were identified in 17 patients (13.6%). Three cases of bile duct injury occurred in the non MRCP group, whereas, no bile duct injury occurred in the MRCP group. No significant statistical difference in postoperative complication was observed in either group. Mean duration of operation was 50.5(±30.4) minutes in the MRCP group, and 52.2 (±29.9) minutes in the non MRCP group (p=0.630). Post operative hospital stay was 2.1 (±1.4) days (mean) in the MRCP group, and 2.5 (±2.5) days in the non MRCP group. No statistical difference was observed between the two groups (p=0.110). Conclusion: MRCP may be useful for evaluation of bile duct anomaly and identification of hidden bile duct stones. However,this modality did not show statistical benefits for postoperative outcomes in patients who underwent laparoscopic cholecystectomy.
백진오,정은영,박우현,최순옥,Baek, Jin-O,Jung, Eun-Young,Park, Woo-Hyun,Choi, Soon-Ok 대한소아외과학회 2011 소아외과 Vol.17 No.1
This study was aimed to evaluate associated congenital anomalies in the patients with esophageal atresia with tracheoesophageal fistula (EA/TEF). Forty-two neonates with the diagnosis of EA/TEF treated over a 10 year period in a single institution were included in this study. The demography of EA/TEF was analyzed. Major associated anomalies including vertebral, anal, cardiac, renal, limb, neurologic and chromosome were reviewed and categorized. Males were slightly more dominant than females (1.47:1) and all patients had Gross type C EA/TEF. Only 19 % of the patients had solitary EA/TEF without associated anomalies. Cardiac anomalies were the most common associated congenital anomaly in patients with EA/TEF (73.8 %). But 47.6 % were cured spontaneously or did not affect patients' life. Atrial septal defect (ASD) was the most common cardiac anomaly followed by patent ductus arterious (PDA) and ventricular septal defect (VSD). Among gastrointestinal anomalies (23.8 %), anorectal malformations were the most frequent, 70 % Vertebral and limb abnormalities accounted for 11.9 % and urogenital malformations 9.5 % of the anomalies in patients with EA/TEF. VACTERL associated anomalies were 23.8 % and 1.8% had full VACTERL. Almost 12 % of EA/TEF had neurologic anomalies. Patients with EA/TEF require preoperative evaluation including neurologic evaluation to detect anomalies not related to VACTERL. Though associated cardiac anomaly occurred in 73.8 % of patients in our study, only 21.42 % needed surgical correction. The authors suggesrs further studies with large numbers of patients with EA/TEF.
N<SUB>2</SUB>O 추진제 분해 촉매의 고온 내열 특성 연구
백진오(Jinoh Baek),김태규(Taegu Kim) 한국추진공학회 2010 한국추진공학회 학술대회논문집 Vol.2010 No.5
아산화질소를 추진제로 사용하기 위해 아산화질소의 촉매 분해 특성과 고온 하에서 내열성을 연구하였다. 기존의 Ru 촉매의 내열성을 개선하기 위해 추가적으로 Al2O3 지지체에 Si를 담지시킨 후 Ru을 담지하였다. 관형 반응기를 이용하여 반응온도에 따른 아산화질소의 전환율을 측정하고, Si 첨가에 의한 분해특성에 대해서 연구하였다. 반응온도가 높을수록 전환율이 우수했고, Ru/Al2O3-Si 촉매가 Ru/Al2O3 촉매보다 높은 전환율을 보였다. The characteristics of thermal-resistance catalyst for N2O propellant decomposition were studied in the present study. Si was added to the Al2O3 support to stabilize its surface area at high temperature (>1000℃). Ru was used as a catalyst for N2O decomposition. The prepared catalysts were characterized using SEM, EDS and XRD analysis, and N2O conversion was measured as reaction temperatures. The Ru/Al2O3-Si catalyst showed better performance than Ru/Al2O3 catalyst.
갑상선 유두암의 예후 예측 인자로서 BRAFV600E 돌연변이의 역할
권택주,백진오,이지연,강진구,황승욱,김완욱,박호용,정지윤,박지영,정진향 대한갑상선-내분비외과학회 2014 The Koreran journal of Endocrine Surgery Vol.14 No.3
Purpose: Papillary thyroid carcinoma (PTC) is the most common malignant tumor of the thyroid and BRAFV600E mutation is the most frequent genetic alteration in PTC. BRAFV600Emutation has been demonstrated as a prognostic biomarker for prediction of poor clinicopathological outcomes, such as increased incidence of extrathyroidal extension, lymph node metastasis, and advanced stage. However, there is conflicting literature regarding the association of BRAFV600E mutation and aggressive clinicopathological features. In this study, we investigated the prevalence of BRAFV600E mutation in PTC and determined the association of BRAF mutation with indicators of poor prognosis for PTC.Methods: We reviewed 1009 patients with PTC, who underwent thyroid surgery at Kyungpook National University Hospital between January 2013 and March 2014. BRAFV600E mutation analysis was performed using real-time polymerase chain reaction based amplification of DNA extracted from paraffin-embedded tumor specimens. Results: BRAFV600E mutation was detected in 863 (85.5%) patients. In univariate analysis, histologic subtype, extrathyroidal extension, and advanced stage showed significant association with BRAFV600E mutation. In addition, concurrent Hashimoto’s thyroiditis showed an association with low prevalence of BRAFV600E mutation. However, no stati-stically significant association was observed for age, gender, multifocal or bilateral tumor, and lymph node metastasis. Multivariate analysis showed an independent association of extrathyroidal extension with BRAFV600E mutation.Conclusion: In this study, extrathyroidal extension of PTC is an independent prognostic factor associated with BRAFV600E mutation status. However, conduct of further large scale studies with long term follow up is required before the BRAF mutation can be conclusively recommended as a prognostic biomarker.
이지연,정진향,김완욱,황승욱,강진구,백진오,김혜정,박지영,정지윤,임재양,박호용 한국유방암학회 2014 Journal of breast cancer Vol.17 No.4
Ectopic breast tissue can occur anywhere along the incompletelyregressed mammary ridge. Among the various types ofbreast choristoma, ectopic breast tissue, which has only glandulartissue without a nipple or areola, is most commonly detectedin axillary areas. However, ectopic breast cancer is often notdetected until significant clinical symptoms have been revealed,or diagnosis is delayed. Furthermore, an examination of ectopicbreast tissue tends to be omitted from a screening mammography. Especially, the microcalcifications of ectopic breast tissueare difficult to delineate on mammography. Herein, the authorsreport a case of ectopic breast carcinoma that showed clusteredmicrocalcifications on screening mammography, and discussthe interpretation and implications of microcalcification inectopic breast tissue.