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      • SCOPUSKCI등재

        암환아 어머니의 사회적지지와 부담감

        백소희,박인숙,Paik So Hee,Park In Sook 한국아동간호학회 1996 Child Health Nursing Research Vol.2 No.1

        The purpose of the study was to identify the degree of social support and burden in mothers of children with cancer, and to determine a strategy of an effective social support utility for burden relief in these mothers. The subjects of this study were consisted of mothers of cancer children, registered at a'C'University affiliated hospital in Taejon. The data was collected from July 1 to August 31, 1994. Three instruments were used to collect the data : a semi-structured interview questionnaire which was developed by the researcher was used to identify the content of the mother's burden, a Visual Analogue Scale(VAS) that had a 10cm horizontal line was used to measure the degree of mother's burden and the PRQ part I & part Ⅱ were used to measure the degree of mother's social support. The content of mother's burden collected through in depth interviews was analyzed using content analysis. Also burden and social support data were analyzed by SAS program. The result of this study were summarized as follows : 1. The data on burden content from the interview were categorized as psychological, physiological, family interaction with maternal role, financial burden and personal interaction with social relational burden. 2. The degree of burden measured by VAS had a mean of 8.04(range from 0.5 to 10). 3. The score for social support measured by PRQ part Ⅱ had a mean of 88.9(range from 71 to 113). The highest scores was for reassurance of worth. The lowest score was for opportunity for nuturance. Most of the 15 mothers received the greatest amount of support from their sisters, spouse, friends, neighbors, relations, priest were perceived as eaningful resource person. 4. The correlation coefficient of burden and social support was somewhat negative correlation but no statistical significance(r=-.072). Therefore, a further study is necessary to repeat the qualitative research for exploring factor to be affected family caregiver's burden according to disease proceeding stage. On the basis of the results from this study, future research will be promoted valid and reliable tool development. Through this study, nurses understand and assess the individual psychologic burden and further it would be recommendated to produce professional education program for pediatric oncologic specialist nurse.

      • KCI등재

        대학생의 진로정체감 지위에 관한 잠재프로파일 분석: 성취목표지향성과 성취정서의 영향력 검증

        백소희,이지혜 한국진로교육학회 2019 진로교육연구 Vol.32 No.4

        This study was conducted to see if the vocational identity status of university students were classified into six categories(achievement, moratorium, foreclosure, diffusion, searching moratorium and undifferentiated) by the Vocational Identity Status Assesment(VISA) model of Porfeli et al.(2011). Then, the effects of achievement goal orientation and achievement emotion on class classification were tested against each vocational identity status. For this purpose, the data were collected from 300 university students at the nationwide level. Then, the vocational identity status was classified through latent profile analysis. In addition, multinominal logistic regression analysis was used to test the effects of achievement goal orientation and achievement emotion on vocational identity status classification. Results were as follows: First, the vocational identity status of university students was classified into five potential groups: ‘foreclosure’, ‘diffusion’, ‘searching moratorium’, ‘achievement’, and ‘undifferentiated’. Second, multinominal logistic regression analysis results revealed that those with low performance-approach goal and self-esteem, and high boredom were likely to belong to the diffusion group. Meanwhile, those with significantly low mastery-avoidance goal and shame were likely to belong to the achievement group. Implications on utilizing achievement goal orientation and achievement emotion for vocational identity development were discussed. 본 연구는 대학생의 진로정체감 지위가 Porfeli 등(2011)의 진로정체감 지위 평가(Vocational Identity Status Assesment; VISA)모델에 의해 여섯 가지 지위인 성취, 유예, 유실, 혼미, 탐색유예, 미분화로 분류되는지 확인하고 진로정체감 지위의 분류에 대한 성취목표지향성과 성취정서의 영향력을 검증하고자 하였다. 이를 위해 전국 시/도 대학생 300명을 대상으로 자료를 수집하였고, 잠재프로파일분석을 통해 진로정체감 지위를 유형화하였다. 또한 다항 로지스틱 회귀분석을 통해 진로정체감 지위 구분에 대한 성취목표지향성, 성취정서의 영향력을 확인하였다. 연구결과, 첫째, 잠재프로파일분석을 통해 VISA척도의 탐색, 몰입, 재고려의 세 차원에 따라 대학생의 정체감 지위가 다섯 개의 잠재집단으로 유의미하게 분류되었으며 각 집단은 ‘유실’, ‘혼미’, ‘탐색유예’, ‘성취’, ‘미분화’로 명명하였다. 둘째, 분류된 다섯 개의 잠재집단에 대한 다항 로지스틱 회귀분석을 실시하여 성취목표지향성과 성취정서의 특성을 파악한 결과 수행접근목표가 낮으며, 성취정서 중 자부심이 낮고 지루함이 높을 때 혼미 집단에 분류되는 것으로 나타났다. 한편, 숙달회피목표가 낮고 성취정서 중 수치심이 낮을 때 성취집단에 분류되는 것으로 나타났다. 본 연구의 결과를 바탕으로 대학생의 진로정체감 발달을 위하여 성취목표지향성과 성취정서를 활용하는 접근에 대한 시사점을 논의하였다.

      • KCI등재후보

        라코사마이드와 관련된 발프로산 독성 1례

        지혜(Ji Hye Baek),김건하(Gun Ha Kim),변정혜(Jung Hye Byeon),소희(So Hee Eun),은백린(Baik Lin Eun) 대한소아신경학회 2016 대한소아신경학회지 Vol.24 No.2

        발프로산은 소아에서 널리 쓰이는 항경련제로 다양한 부작용과 약물 상호작용이 보고되어 왔다. 반면, 새로운 항경련제인 라코사마이드는 약물 상호작용이 거의 없는 것으로 알려져 있다. 본 증례는 열성 질환 이후 나타난 라코사마이드와 관련된 발프로산 독성(고암모니아혈증)에 대해 보고한 두번째 증례이다. 라코사마이드를 증량한지 18일후 과도한 기면이 발생했으며 당시 혈중 발프로산 농도(>150 μg/mL)가 상당히 높았고 이후 3일뒤 혈중 암모니아 수치(232 N­μg/dL )가 급격히 증가하였다. 라코사마이드와 발프로산을 중단하고 엘카르니틴을 추가한 이후 4일만에 혈중 암모니아 수치가 정상화되고 환자는 의식이 명료해졌다. 발프로산의 독성이 새로운 항경련제의 추가나 발열과 연관되어 안정적인 치료 중에도 언제든 발생할 수 있어 약물 농도 및 부작용에 대한 주의깊은 관찰이 필요하다. Valproic acid (VPA) is a widely used anticonvulsant drug having various adverse effect and drug interaction. In contrast, newer antiepileptic drug, lacosamide has been known to have minimal drug interaction. We report the second case of lacosamide-associated valproic acid toxicity presenting as hyperammonemia following febrile illness. Prior to hospital admission, this 13-year-old girl had been treated with multiple antiepileptic drugs including valproic acid for 11 years with no any adverse effect. Lacosamide had recently been added due to poorly controlled seizures. The patient presented with excessive drowsiness 18 days following an increase in lacosamide dosage up to 7.5 mg/kg/day. Laboratory tests revealed elevated levels of VPA(> 150 ug/ml) and hyperammonemia (232 N-μg/dL). Eight days prior to admission, the patient suffered a 1-day fever as a result of influenza A infection and did not take an antiviral agent. Lacosamide and valproic acid treatments were discontinued, while treatment with L-carnitine was added. After 4-days, ammonia levels decreased to 144 N-μg/dL, and the patient became alert. In conclusion, valproic acid toxicity may occur at any time during the stable course of medical treatment, though patients may be more susceptible following the addition of new anti-epileptic drugs or febrile illness.

      • KCI등재후보

        Prognosis in Late-Onset Febrile Seizure

        지혜,황순영,변정혜,소희,은백린,김건하 대한소아신경학회 2017 대한소아신경학회지 Vol.25 No.4

        Purpose: There is a paucity of evidence about prognosis after a first febrile seizure in older children. We investigated the prognosis and potential risk factors associated with subsequent unprovoked seizures in children who had experienced a first febrile seizure over 6 years of age, which we termed as late-onset febrile seizure. Methods: We included all patients six years or older who presented to the emergency department with a febrile seizure between 2009 and 2015. Clinical data was collected by chart review and parents were contacted for information on seizure progress. We used the Cox proportional-hazards model and Kaplan-Meier analysis for evaluating the risk factors for subsequent unprovoked seizures. Results: Of 247 patients, we excluded 168 children who had a history of epilepsy, unprovoked, or febrile seizure and who were followed-up for period less than six months. Overall, 79 patients were classified as having had a first late-onset febrile seizure. During follow-up of 34.9±25.7(mean±SD) months, unprovoked seizure recurred in 7 of 79 patients (9%). The cumulative probability of seizure recurrence was 4% at 6 months, 6% at 1 year and 9% at 2 years. Clinical variables predictive of subsequent unprovoked seizures were not proved. Conclusion: This is the first multicenter study focusing on prognosis after a late-onset febrile seizure in children six years or older. The percentage of subsequent unprovoked seizure in patients with late-onset febrile seizure was 9% at 2 years of follow-up. Prospective follow-up study with longer duration is warranted.

      • KCI등재

        Differences in Factors Associated with Albuminuria according to Gender and Comorbidities of Hypertension and Diabetes

        장미애,소희,노혜미,천선영,오혜영,박경희,유진,송홍지 대한가정의학회 2015 Korean Journal of Family Medicine Vol.36 No.6

        Background: This study examined the differences in factors associated with albuminuria according to gender and comorbidities of hypertension (HTN) and diabetes mellitus (DM). Methods: We included 3,859 participants aged 20 to 79 years (55% female) from the 5th Korea National Health and Nutrition Examination Survey. Participants were excluded if they took antihypertensive or anti-diabetic medication, had chronic renal failure, had malignant tumor, were pregnant or menstruating during the health examination, or had missing urine albumin data. Albuminuria was defined by the participant’s urine albumin-creatinine ratio (uACR). Relationships between dependent and independent variables were analyzed using the Pearson’s correlation test and simple linear regression. Due to possible muticollinearity, multiple linear regression analysis was used to determine whether the association between the dependent and independent variables of interest remained significant after adjustment for other potentially confounding independent variables. Results: The variables significantly correlated with uACR were different between the genders and between subjects with HTN or DM as a comorbidity. In the multiple linear regression models, hemoglobin A1c (P=0.01) was positively associated with uACR in men without HTN and DM. In men with HTN or DM, systolic blood pressure and fasting glucose (P<0.01) were positively associated with uACR. In women with HTN or DM, waist circumference (P=0.011) and gamma-glutamyl transpeptidase (P<0.001) were positively correlated with uACR (P<0.05) and glucose level (P=0.019) was negatively correlated with uACR. Conclusion: The study suggested factors correlated with albuminuria were different for men and women according to comorbidities such as HTN and DM.

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