보고편 - 대한가정학회 제50차 총회 및 창립 50주년 기념 학술대회 ( 주제 : 인간과 생활환경 ) 분야별 발표논문 초록 - 식생활 , 가족 : 홀어머니 가정에서 사는 아동들의 복지에 관한 종단적 연구

백선영 대한가정학회 1997 Family and Environment Research Vol.35 No.6

다중사용자 환경에서 공간적인 다이버시티를 이용하는 초광대역 통신시스템의 성능 비교분석

백선영,안진영,이성신,김상준,Baek, Sun-Young,An, Jin-Young,Lee, Sung-Sin,Kim, Sang-Choon 한국정보통신학회 2007 한국정보통신학회논문지 Vol.11 No.11

본 논문에서는 다중 수신안테나가 제공하는 공간적인 다이버시티를 이용하여 고속의 데이터 전송률을 달성하기 위한 초광대역 통신시스템의 성능 향상에 대해 연구한다. 다중사용자 간섭 신호들이 존재하는 환경에서 2PPM(Binary Pulse Position Modulation) THMA(Time Hopping Multiple Access) UWB 시스템의 성능을 이론적으로 분석하기 위해서 다중 수신안테나를 통해서 수신되는 공간적인 신호들을 결합한 후의 수신 SINR 표현식을 유도하고 BER 성능을 수치적인 시뮬레이션에 의해 평가된다. 또한 2PPM에 의한 시스템의 성능 결과들을 2PAM(Binary Pulse Amplitude Modulation) THMA UWB 시스템의 이론적인 성능 결과와도 비교한다. 공간적인 다이버시티가 2PPM과 2PAM THMA UWB 시스템의 성능에 미치는 영향을 분석한다. 다중 수신안테나의 수가 증가함에 따라 BER 성능이 향상됨을 보인다. 또한 다중사용자 간섭 신호들이 존재할 때 2PAM THMA UWB 시스템의 성능이 2PPM THMA UWB 시스템의 성능보다 상당히 우수하다는 것을 확인한다. In this paper, the performance improvement of ultra-wideband(UWB) communications system to achieve high-data-rate using spatial diversity provided by multiple receive antennas is investigated. We derive the expression for the received SINR after spatially combining through multiple receive antennas and evaluate the bit error rate(BER) performance by numerical simulation. We also compare the performance results in the case of 2PPM systems with the theoretical performance results in the case of 2PAM THMA UWB systems. The impacts of spatial diversity on the performance of 2PPM and 2PAM THMA UWB systems are analyzed. It is shown that the BER performance is improved as the number of receive antennas increases. Also, it is observed that in the presence of multiple user interference signals, the performance of 2PAM THMA UWB systems is considerably superior to that of 2PPM THMA UWB systems.

Potential use of transgenic domestic pigs expressing recombinant human erythropoietin in diabetes translation research

백선영,정학재,김경운,조규호,최인철,이훈택 한국통합생물학회 2019 Animal cells and systems Vol.23 No.1

Recently, diabetes mellitus (DM) has shown rapid global increases with about five million deaths annually. Animal models are imperative to understand disease mechanisms and develop diagnostic, preventive, and therapeutic interventions in translational research. Rodent and minipig models have been established and widely used for DM research. However, domestic pig models are limited in spite of advantages such as pharmacokinetic and physiopathological availability. This study examines the potential use of domestic pigs expressing recombinant human erythropoietin (rhEPO) as disease and therapeutic response models for DM. We previously generated transgenic pigs (n = 16, EPO Tg) in which rhEPO was expressed and circulated in all organs. Thirty-two pigs, including 16 controls, were fed high fat (HF) diets for 42 weeks. Subsequently, blood samples for chemical and metabolic analysis were collected after fasting for 24 h and glucose loading for oral glucose tolerance tests (OGTTs). We found increased activation of the PI3 K/Akt signaling pathway under hypoxic conditions after rhEPO treatment, and HF diet-inducible-obesity in the EPO Tg and control pigs. OGTTs showed lower fasting glucose levels in the EPO Tg pigs than in controls before and after the HF diet, suggesting that rhEPO may affect glucose concentrations. Insulin and C-peptide concentrations responded slowly to glucose administration and returned to initial levels after 2 h. The blood test results suggest that EPO might affect metabolic and chemical components such as glucose, high-density lipoprotein, glucagon, triglyceride, and free fatty acid. Our findings support the use of rhEPO transgenic domestic pigs as model animals for translational DM research.

냉동식품 중 Listeria monocytogenes의 분포 조사 및 시험방법에 관한 연구

백선영,곽효선,차진,박성국,임순영,김형일,박선희,김창민 식품의약품안전청 1997 식품의약품안전청 연보 Vol.1 No.-

최근 급속히 소비가 증가되고 :긴는 냉동식품을 대상으로 교 monoef09☞HfS의 오염도를 확인하오 분리균웨 특성 조사 및 신속 시험법을 확립하고자 서울, 부산 둥 5개 지역에서 판매 되고 있는 냉동식품을 구입하여 쿄 monoe-frgrnes를 분리, 동정하고 분리균에 대하여는 혈청형 조사 및 항생제 내싱 검사를 실시하였다. 냉동피자, 만두, 식육 및 수산물 가공품 둥 총 624건의 냉동식품을 구입하여 L uonoefof☞nog뫼 오염도를 조사한 결과 55건(9.5%)의 검체에서 t raonoofog☞oeg가 검출되첬으며 각 식품군별로는 냉동 만두 5.a%, 피자류 12.8%, 식욱가공품 10.4%, 해산물 기공품 9.1%, 기타 8.8%에서 양성률을 나타내었다. 분리균의 혈청형은 type 1이 87.5%를 나타내었으며 type4가 12.5%, 기타가 3.6%를 나타내었다. 항생제 내성 시험 결과 대부뚠의 항생제체 대해 감수석을 나타내었으나 nalidixic ac펀, polyrnyxin 8에 대하여는 저항성을 나타내었다. 또한 Hernolysin gene (fJy 1, ffy 2)과 Internalin gene (inf 1, inf2)의 mixed primer를 이용하여 최종 확인을 위한 신속하교 정확한 시험법인 multi-pleB PCR 분석법을 확립하였다. 표준균준 및 분리균의 DNA 추출을 위하여 Iysozyme (3mg/m쓰과 Proteinase (200fe/mf)처리 및 boiling을 싫시하였다. PCR 후 전기영동시 교 mortoofofeneg의 표준균주와 분리균은 446bp와 714bp band를 나타낸 반면 t innocua와 교. iuanovi 균주는 band를 나타내지 않았다. We surveyed the dfstribution of L. monocytogenes with five groups of frozen fooods. Six hundreds twenty four samples of frozen foods were randomly purchased in the market and tested. Fifty nine samples were ploved to be L. monocytogenes (9.5%) including kyoza(4.3%), pizza(12.8%), processed meat foods (10.4%), processed sea foods(9.1%), other frozen foods (10.5%). Serotypes of those isolates were; serotype 1(87.5%), type 4 (12.5%) and others (3.1 %). Also, isolates were tested for the antibiotic susceptibility. They were resistant to nalidixic acid, streptomycin, and polymyxin B and sensitive to ohlorarnphenicol, ampicillin, carbenicillin, tetracycline, tobramycin, gentamicin, kanamycin. neomycin, norfloxacin, ciprofloxacin, trimethoprim sulfamethoxazale. A multiplex-PCR method for rapid confirmation of L. monocytogenes was applied to the isolates.. We developed a new PCR technique to extract DNA form the cell. Treatmient of lysezyme (2mg/ml), proteinase (200㎍/m1) and boiling (15 min) were carried ou. hly 1, hly 2 and inl 1, inl 2 were used as primers. Standard strains and isolates of L. monocytobenes showed a specific amplified products of 719 bp and 446bp. These fragment was not shown with L. innocua andd L. ivanovii samples on agarose gel electrophoresis.

경영 TREND-정보화 사회에서 개념과 감성의 사회로

백선영,Baek, Seon-Yeong 한국지역냉난방협회 2007 집단에너지 Vol.5 No.-

꿈의 오케스트라 바이올린 단원의 경험과 이에 따른 변화 탐색

백선영 한국음악교육학회 2019 음악교육연구 Vol.48 No.3

The purpose of this study was to discover the experiences and changes of the violin student’s in the ‘El Sistema Korea’ orchestra program. Participating observations, classroom observations, activity journals, group interviews and in-depth interviews with participants in the study, and recordings were taken in order to collect data for this research. The conclusions of this study are as follows. First, ‘El Sistema Korea’ orchestra education has allowed students to experience a variety of activities that they have never experienced in a more practical way before, which has contributed to expanding there artistic experience. Second, the ‘El Sistema Korea’ orchestra education has improved the students’ self-confidence and self-esteem, and these personal changes have produced positive improvements in their social skills. Finally, the students’ interest to enjoy music in life, to major in music, and to enjoy art in life improved consistently through the ‘El Sistema Korea’ orchestra education. However, despite these positive factors, the opportunity costs to study was a decisive factor in forcing them to abandon their orchestra education.

우유중 잔류 항생물질 분석방법에 관한 비교연구

백선영,김형일,박건상,김소희,권경란 한국식품위생안전성학회 1996 한국식품위생안전성학회지 Vol.11 No.2

Recently, as concern about the residual antibiotics in milk increase, the detection methods of residual antibiotics used extensevely at the present time were investigated and compared to their properties and the detection limits of variable antibiotics. At first, comparative tests of the detectable sensitivity of 4 teat organisms, B.cereus, B.subtilis, M.luteus, B. stearothermophilus C-953, were performed by disc assay. As a result, B.stearotleermoph.ilus was the most sensitive strain of all other strains and showed the detect limit of 5-50 ppb for penicillins (PCs). And also, B.subtilis was showed the more effective detection limit, 200-400 ppb, for aminoglycosides (AGs) and M.luteus was showed predominant sensitivity , 50-500 ppb for macrolides(MLs) and B.cereus was the most sensitive strain for tetracyclines (TCs) and showed the detection limit of 100-400 ppb. Therefore, each test strains were showed a different sensitivity in the detection of the different antibiotic families. When the detection limit of disc assay and other methods were compared, TTCmethod was less sensitive than other methods showing 5-50 ppb detectable lebel for PCs. Also, for the detection of other antibiotic families TTC method was showed the worst sensitivity and Delvo and Charm Farm tests were similar to the detectable properties of AGs and MLs. Although disc assay was showed the similar detection limit for PCs with Delvo and Charm Farm, it was more widely effective for the detection of kanamycin, erythromycin, chlortetracycline, doxycycline, verginiamycin and so on than Delvo or Charm Farm. CharmII test was showed the best sensitivity for the most of antibiotics except neomycin and gentamycin. But it was necessary that different tests must be performed to each antibiotic family and so it was regarded that the effectiveness of that method was low.

우유중 잔류 항생물질 분서방법에 관한 비교연구

백선영,김형일,박건상,김소희,권경란 한국식품위생안전성학회 1996 한국식품위생안전성학회지 Vol.11 No.2

Recently, as concern about the residual antibiotics in milk increase, the detection methods of residual antibiotics used extensevely at the present time were investigated and compared to their properties and the detection limits of variable antibiotics. At first, comparactive tests of the detectable sensitivity of 4 test organisms, B. cereus, B. subtilis, M.luteus, B.stearothermophilus C-953, were performed by disc assay. As a result, B.stearothermophilus was the most sensitive strain of all other strains and showe the detect limit of 5-50 ppb for penlicillins (PCs). And also, B.subitilis was showed the more effective detection limit, 200-400 ppb, for aminoglycosides (AGs) and M.luteus was showed predominant sensitivity , 50-500 ppb for macrolides(MLs) and B.cereus was the most sensitive strain for tetracyclines (TCs) and showed the detection limit of 100-400 ppb. Therefore, each test strains were showed a different sensitivity in the detection of the different antibiotic families. When the detection limit of disc assay and other methods were compared, TTCmethod was less sensitive than other methods showing 5-50 ppb detectable lebel for PCs. Also, for the detection of other antibiotic families TTC method was showed the worst sensitivity and Delvo and Charm Farm tests were similar to the detectable properties of AGs and MLs. Although disc assay was showed the similar detection limit for PCs with Delvo and Charm Farm, it was more widely effective for the detection of kanamycin, erythromycin, chlortetracycline, doxycycline, verginiamycin and so on than Delvo or Charm Farm. CharmII test was showed the best sensitivity for the most of antibiotics except neomycin and gentamycin. But it was necessary that different tests must be performed to each antibiotic family and so it was regarded that the effectiveness of that method was low.

Corynebacterium세균의 이종간 원형질체 융합에 의한 재조합주의 유전학적 분석과 L-glutamate 와 L-glutamine 생성

백선영,이혜경,최순영,김종욱,이세배,임번삼,민경희 한국산업미생물학회 1990 한국미생물·생명공학회지 Vol.18 No.3

자외선 조사와 NTG를 처리하여 Brevibacterium flavum 10AHR(arg his Rif^r)과 Corynebacterium glutamicum 11TS(trp Sm^r)의 돌연변이주를 분리하였다. B. flavum 10AHR과 C. glutamicum 11TS를 300㎍/㎖의 lysozyme으로 18시간 처리하여 원형질체를 형성하고, 융합시 30%의 PEG 6,000으로 처리하였을 때 가장 높은 3.7×10 exp(-6)의 융합빈도를 나타내었다. 재조합주의 유전적 분석결과 재조합주들은 FMM(Rif^r Sm^r), FA(Rif^r Sm^r arg), FH(Rif^r Sm^r his), FT(Rif^r Sm^r trp), FAH(Rif^r Sm^r arg his), FAT(Rif^r Sm^r arg trp), FAHT(Rif^r Sm^r arg his trp)으로 분류되었다. FAH에 속하는 균주들은 대부분 모균주에 비해 glutamate와 glutamine의 생산성이 월등히 증가하였으며, FAH1의 경우 glutamate 생성에 있어 모균주인 B. flavum 10AHR에 비해 12배, glutamine은 모균주인 C. glutamicum 11TS에 비해 2.6배 정도 생성이 현저히 증가하였다. 재조합주들의 효소활성을 측정해본 결과 glutamate와 glutamine의 생성량은 GDH와 GS의 활성도와 각각 관련이 있음을 알 수 있었다. For interspecific portoplast fusion, Brevibacterium flavum 10AHR(Rif^r arg his) and Corynebacterium glutamicum 11TS(Sm^r trp) were induced by UV and NTG treatment. The protoplast fusion frequency between B. flavum 10AHR and C. glutamicum 11TS was 3.7×10 exp(-6) with the lysozyme treatment(300㎍/㎖) for 18 hrs. Genotypes of recombinants were analized as FMM(Rif^r Sm^r), FA (Rif^r Sm^r arg), FH(Rif^r Sm^r his), FT(Rif^r Sm^r trp), FAH(Rif^r Sm^r arg trp), FAT(Rif^r Sm^r arg trp), and FAHT(Rif^r Sm^r arg his trp). FAH 1 produced 12 fold of glutamate production compared to parental type, B. flavum 10AHR. In glutamine productivity, it produced 2.6 fold to parental type, C. glutamicum 11TS. Production of glutamate or glutamine by recombinants was involved in the specific activities of glutamate dehydrogenase(GDH) and glutamine synthetase(GS), respectively.

서울대기중 아질산기체의 계절별 농도변화

백선영,이용근,이동수 대한환경공학회 1993 대한환경공학회 학술발표논문집 Vol.1993 No.12