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배태희,유영일,김우섭,김한구 대한두개안면성형외과학회 2009 Archives of Craniofacial Surgery Vol.10 No.2
Purpose: The aim of this study is to establish anatomical dimension of the nose and nostril shape in Korean twenties. Methods: Authors measured anthropometry of nose in Korean youths 1,000 individuals (male 363, female 637) and analyzed stastically them. Results: The mean measurements are as follows. 1. The shape of nostrils was classified into 7 types by the angle between both long axis of nostril (male / female). Type Ⅰ (<40°)1.7% / 1.72%, Type Ⅱ (41 - 70°) 26.17% / 29.35%, Type Ⅲ (71 - 100°) 39.94% / 38.77%, Type Ⅳ (unclassified) 3.85% /5.80%, Type Ⅴ (101 - 130°) 20.93% / 17.89%, Type Ⅵ (131-180°) 7.43% / 5.96%, Type Ⅶ (>180°) 0% / 0.47% 2. Lengths (male/female) Width of nasal root: 25.29 ± 2.25 mm / 24.72 ± 2.40 mm Width of nose: 37.63 ± 2.46 mm / 34.77 ± 2.11 mm Width of columella: 7.18 ± 0.92 mm / 6.92 ± 0.86 mm Width of alar: 4.99 ± 1.00 mm / 4.74 ± 0.91 mm Width of nostril floor: 10.98 ± 1.40 mm / 10.13 ± 1.73 mm Protrusion of nasal tip: 17.12 ± 1.95 mm / 16.88 ± 1.84 mm Length of alar: 27.10 ± 2.21mm / 24.66 ± 2.18 mm Length of nasal root: 17.37 ± 2.51 mm / 16.08 ± 2.90 mm Depth of nasal root: 7.83 ± 1.63 mm / 6.82 ± 1.36 mm Length of columella: 8.13 ± 1.40 mm / 7.30 ± 1.46 mm Height of nose: 60.50 ± 8.90mm / 59.14 ± 9.22 mm Height of nasal bridge: 52.68 ± 7.49 mm / 50.57 ± 7.71 mm3. Angles Nasofacial angle: 30.19 ± 3.43° / 29.13 ± 6.31° Nasofrontal angle: 134.88 ± 7.25° / 139.94 ± 6.33° Nasolabial angle: 95.08 ± 8.95° / 95.80 ± 8.93° 4. Nasal index: 72.60 ± 9.57% / 68.21 ± 7.03% Nasal tip protrusion-nasal height index: 45.64 ± 5.21% / 47.09 ± 5.21% Nasal tip protrusion-nasal width index: 32.61 ± 6.83% / 31.63 ± 6.71% Conclusion: These data could be useful reference for anthropometry of nose in Korean twenties.
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배태희,김종찬,김우섭,김한구,김승홍 대한성형외과학회 2007 Archives of Plastic Surgery Vol.34 No.1
Purpose: Photogrammetry has been introduced as an alternative to direct measurement to obtain facial distances for a variety of anthropometric applications. The aim of this study is to establish morphological and functional value of an eye in Korean youths using specially designed computer software with digital photographic images.Methods: Authors measured anthropometry of an eye in Korean youths 1,449 individuals(622 males, 827 females) and analyzed stastically them. Results: The mean measurements are as follows. The diameter of cornea was 11.6±0.9mm in males and 11.3±0.9mm in females. The vertical dimension of palpebral fissure was 7.4±1.7mm in males and 8.2±1.6mm in females. The intercanthal width was 35.8 ±3.2mm in males and 34.4±2.9mm in females. The biocular width was 90.4±5.7mm in males and 87.4±5.3mm in females. The endocantion-superior margin of palpebral fissure distance was 12.7±1.4mm in males and 11.6±1.4mm in females. The horizontal dimension of palpebral fissure was 28.5±2.2mm in males and 27.4±1.9mm in females. The slant of palpebral fissure was 10.7±2.6° in males and 11.3±3.0° in females. The height of upper eyelid was 10.6±2.3mm in males and 10.7±2.3mm in females. The width of double fold was 2.0±0.7mm in males and 1.9±0.6 mm in females. A double fold was seen in 21.9% of males and 44.9% of females. The most frequent shape of the double fold was type IV. The most common type of epicanthal fold was type III in both males and females.Conclusion: Photogrammetic measurement of large population using specially designed software could offer reliable data and these data could be useful reference for preoperative consultation, surgical planning and anthropometic study of eye.
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토끼 귀에 발생한 초기 창상 반흔에 베라파밀이 VEGF의 발현 및 세포자멸사에 미치는 영향
배태희,김우섭,김한구,김미경 대한성형외과학회 2009 Archives of Plastic Surgery Vol.36 No.1
Purpose: Excessive scarring in the forms of keloid and hypertrophic scar could be a consquence of the accumulation of granulation tissue cells due to aberrant control of apoptosis. Verapamil retard extracelluar matrix production and inhibits VEGF production in primary cultured keloid fibroblast. The object of this study was effect of verapamil on VEGF expression and apoptosis in early wound scarring of the rabbit ear. Methods: Full thickness wounds were created on the ventral side of 6 New Zealand rabbits's ear. 16 days after initial wounding verapamil and saline were injected each scars and scars were harvested 1 week, 2 weeks, 4 weeks later. The wounds were stained with hematoxylin and eosin, TUNEL stain, immunohistochemical stain for VEGF and calculated scar elevation index. Results: Histologic analaysis demonstrated significant reduction in inflammation, vascularity and improvement in dermal collagen organization in experimental group. In TUNEL staining apotosis positive cells were increased and immunohistochemial staining of VEGF demonstrated significant reduction of VEGF expression in experimental group. No significant difference was noted in scar elevation index between two groups. Conclusion: This study suggest that intralesional injection of verapamil on early wound scarring of the rabbit ear decreased VEGF production and increased apoptosis and have a benefit on the pathophysiology of scar formation.
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태아 흰쥐의 창상치유에서 Fas, Fas Ligand 및 bcl-2의 발현
배태희,김한구,박대숭,김우섭,김승홍,이태진 대한성형외과학회 2004 Archives of Plastic Surgery Vol.31 No.2
Cutaneous wound healing in adult humans and higher vertebrate animals results in scar formation. In contrast, both human and animal fetuses at early gestational ages exhibit skin wound healing without scarring. A recent study has suggested that apoptosis occurs and plays an important role in achieving a decrease in cellularity during skin wound healing. The purpose of this study is to reveal the hypothesis the apoptosis may decreases the inflammatory infiltrates in fetal skin wound healing and may affect the fetal scarless wound healing.Open full-thickness incisional skin wounds were created on fetal rats at gestational ages 16 days(term= 21days). Wound were harvested at 24 hour(n=15), 72 hour(n=15), 120 hour(n=15). Adult skin wound was harvested at 24 hour(n=15), 72 hour(n=15), 120 hour(n =15). The wounds were fixed and stained with hematoxylin and eosin, TUNEL stain, immunohistochemical stain for Fas, Fas ligand, bcl-2. Fetal wounds was healed without scar formation and with regeneration of normal dermal and epidermal appendage architecture. Immunohistochemical staining for Fas, Fas ligand shows sparse positive cells in squamous epithelium of the both adult and fetus, there are no difference of expression between two groups. Immunohistochemical stainings for bcl-2 shows no positive cells in both adult and fetus. The apoptotic index of adult is 0.65±0.32 and fetus is 0.56 ±0.37(p=0.464), there is no significant difference stastically between two groups.These data indicate that apoptosis is not likely to be related to decreased infiltration of inflammatory cells that is main factor of scarless fetal wound healing.
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확장광배근피판을 이용한 화상 후 반흔 유방의 재건 2례
배태희,김한구,김우섭,Bae, Tae-Hui,Kim, Han-Koo,Kim, Woo-Seob 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.1
Purpose: Authors present the case of 2 patients who underwent extended Latissimus dorsi myocutaneous flap to reconstruct postburn breast deformity. Methods: A 39-year-old woman and 18-year-old woman with postburn breast deformity visited for reconstruction. The nipples were preserved but normal breast development did not occur due to scar contracture. Burn scar contracture was released by excision of the restricting burn scar and breast mound was reconstructed with extended Latissimus dorsi myocutaneous flap. Additional contracture release with multiple z-plasty was performed at the axillae and medial portion of breast. Results: Postburn breast reconstruction using Latissimus dorsi myocutaneous flap showed natural shaped breast mound and inframammary fold. There was no significant complication in both cases. Conclusion: Latissimus dorsi myocutaneous flap provide sufficient skin and soft tissue and it could be an effective method for reconstruction of postburn breast deformity.
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