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배재문,한호성,김영우 梨花女子大學校 醫科大學 醫科學硏究所 1996 EMJ (Ewha medical journal) Vol.19 No.2
목적: 림프관종은 흔한 질환이 아니므로 보고된 례들도 많지 않아 그 임상적 특성이 매우 다양하게 보고되어 있다. 저자들은 최근 2년 6개월간 14례의 림프관종을 경험하였기에 림프관종의 임상적 특성을 분석하는 것이 의의가 있을 것으로 판단하였다. 방법: 1993년 9월부터 1996년 3월까지 이화여자대학교 의과대학부속 목동병원에서 치료받았던 14례의 림프관종에 대하여 임상기록을 통한 후향적 분석을 하였다. 임상적 특성은 증상, 종양의 위치, 지난방법, 종양의 크기, 치료방법 그리고 합병증 및 재발여부에 관하여 분석을 하였다. 결과: 1) 림프관종 발견 연령분포는 4주 이내가 4명, 4주 이상 2세 이하가 4명이었고 2세 이상 10세 이하가 3명이었으며 남자가 6명, 여자가 8명으로서 남녀비가 1 : 1.3 이었다. 2) 증상으로는 신체 각 부위의 종괴로 나타나는 경우가 71.4%로서 가장 많았다. 3) 발생부위는 전흉벽과 액와부에 가장 많이 발생하였다. 4) 림프관종의 진단방법으로는 초음파가 유용한 진단적 가치가 있었다. 5) 림프관종의 크기는 5cm 이하가 6례(42.9%), 5cm 이상 10cm 이하가 6례(42.9%), 10cm 이상 15cm 이하가 2례(14.2%)였다. 6) 치료방법의 주류는 완전절제이며 수술후 합병증이나 재발의 례는 없었다. 결론: 림프관종은 종괴의 감별진단에서 꼭 염두를 두어야 하며 특히 소아의 종괴일 경우 림프관종을 감별하여야 한다. Objectives : Lymphangioma is an infrequent disease. Few cases of lymphangioma has been reported, so its clinical characteristics are variale. We had experienced fourteen patients of lymphangioma during relatively short period, two and half years. It was worth to analyze the clinical characteristics of the lymphangioma. Methods : A clinical analysis was made in fourteen patients with lymphangioma who had been admitted to Ewha Womans University Mokdong Hospital from September, 1993 to March, 1996 retrospectively by the review of clinical records. The characteristics were about the symptoms, locations, diagnostic methods, sized of tumor, treatment, and complications. Results : were summerized as following 1) The sex ratio was 1 to 1.3(male to female) and the most prevalent age group was less than 10 years(78.6%) 2) The most common presenting symptom was a mass(71.4%) 3) The locations were trunk and axillary(35.7%), retroperitoneum(21.4%), extremity(21.4%), neck and mesentery in decreasing order. 4) The ultrasonogram was a useful disgnostic method of lymphangioma(71.4%). 5) The size distribution of tumors were 42.9% in less than 5cm, 42.9% in 5 to 10cm, and 14.2% in 10.1 to 15cm. 6) The treatment of choice was complete excision. There was no complication, or recurrence. Conclusion : lymphangioma should be considered as differential diagnosis in patients with mass, especially children.
Pefloxacin이 난치성 외과적 감염에 미치는 영향
배재문,박규주,윤여규,김진복 대한화학요법학회 1990 대한화학요법학회지 Vol.8 No.2
Resistance of bacterial pathogens to antibiotics is a problem that increases from year to year often resulting from indiscriminate use of β-lactam antibiotics and aminoglycosides. Pefloxacine, a new quinolone derivative, has been shown to have a broad spectrum of antibacterial activity with less resistance. In order to evaluate their efficacy and safety in surgical patients, 30 patients (24 patients with postoperative wound infection, 6 patients with postoperative sepsis) were given pefloxacin 400㎎ bid i.v. for 5 days. The results of treatments are as follows: 1. Overall efficacy of pefloxacine was 96.6% 2. In all but 3 of 19 patients with documented initial pathogen, bacteriologic eradication of the pathogen were achieved(84.2%) 3. Hematologic and biochemical assays performed before, during, and 5 days after pefloxacin did not reveal any adverse effects. 4. Side effects of pefloxacine were observed in 5 (16.6%) patients. 4 patients had nausea, and 1 patients had urticaria, The side effects were usually mild except in 1 patients who had to discontinue pefloxacine due to severe hausea. It can be concluded that pefloxacine is a safe and effective antibiotics that can be used in surgical patients with complicated infections.