신생아에서 Vancomycin 내성 장구균 감염 1례

배수정,최귀전,김천수,이상락,김홍식,강진무,Bae, Soo Jung,Choi, Gui Jean,Kim, Chun Soo,Lee, Sang Lak,Kim, Heung Sik,Kang, Chin Moo 대한소아감염학회 1999 Pediatric Infection and Vaccine Vol.6 No.2

VRE 감염증은 항균제의 과다한 사용 후 출현하는 새로운 형태의 감염성 질환으로, 현재 심각한 임상 문제로 대두되고 있다. 최근 국내에서도 신경학적 장에나 당뇨병, 종양 등의 기저질환을 가진 성인 환자들에서 소수의 감염 예가 보고되고 있으나 소아기, 특히 신생아에서의 감염증은 잘 알려지지 않았다. 저자들은 생후 4일된 신생아에서 발생한 vancomycin 내성 E. faecalis 패혈증 l례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Vancomycin-resistant enterococcus(VRE) was first isolated from various specimens of patients with renal failure or leukemia in 1988. Thereafter VRE has been increasing gradually and became one of the clinically important palhogenic organisms currently. We experienced a case of E. faecalis sepsis in a 4 day old neonate. She was born at 39 weeks gestational age with 2,900gm weight by Cesarean section delivery due to breech presentation. She had had swelling and motion limitation of the left knee joint with fever for one day at age of 4 day and was transfered to our hospital. Ultrasonographic examination of her left knee joint showed some inflammatory change. E. faecalis was isolated from the blood. The organism showed resistance to vancomycin on drug susceptibility test using BHI agar screening test and disk diffusion method. After treatment with ampicillin-sulbactam for 3 weeks the baby was improved. Although VRE infection has been considered rare in Korea. considerable number of demonstrative studies about VRE isolation have been reported recently thus adequate countermeasures are needed to reduce the emergence and prevent nosocomial spreading of this organism.

분열효모에서 THO 복합체의 구성요소인 Tex1/THOC3가 생장 및 mRNA 방출에 미치는 영향

배수정,고은진,윤진호,Bae, Soo Jeong,Koh, Eun-Jin,Yoon, Jin Ho 한국미생물학회 2017 미생물학회지 Vol.53 No.4

진핵생물에서 THO/TREX 복합체는 전사 신장, pre-mRNA 가공 및 mRNA의 핵에서 방출에 중요한 역할을 담당한다. 이 복합체는 진화적으로 잘 보존되어 있지만, 생명체에 따라 구성성분과 기능에 차이가 존재한다. 이 논문에서는 출아효모보다는 고등생물과 더 유사한 분열효모 Schizosaccharomyces pombe에서 THO/TREX 복합체의 한 구성요소인 spTex1가 생장과 mRNA의 방출에 필수적이지 않다는 것을 보였다. spTex1 유전자의 결실과 과발현 어느 것도 생장의 결함과 $poly(A)^+$ RNA가 핵 안에 축적되는 현상을 거의 보이지 않았다. 또한 spTex1-GFP 단백질은 주로 핵 안에 위치하였다. Yeast two-hybrid와 Co-immunoprecipitation 분석에서 S. pombe Tex1은 THO/TREX 복합체의 주요 구성인자인 spHpr1 (THOC1), spTho2 (THOC2)과 상호작용을 하였다. 이와 같은 결과들은 S. pombe의 Tex1도 THO/TREX 복합체의 구성인자이지만, 생장과 mRNA 방출에는 중요한 역할을 하지 않음을 의미한다. In eukaryote, THO/TREX complex plays a critical role in transcriptional elongation, pre-mRNA processing, and nuclear mRNA export. This complex is evolutionally well- conserved, but there are some differences in composition and function according to organisms. Here we showed that spTex1, a component of THO/TREX complex, is not essential for growth and mRNA export in a fission yeast, Schizosaccharomyces pombe, which is more similar to higher eukaryote than budding yeast. Deletion and overexpression of the spTex1 gene do not lead to any detectable growth phenotype and accumulation of poly(A)+ RNA in the nucleus. And the spTex1-GFP protein is localized mainly in the nucleus. Yeast two-hybrid and Co-immunoprecipitation analysis showed that the spTex1 protein interacted with spHpr1 (THOC1) and spTho2 (THOC2), main subunits of THO complex. We conclude that the S. pombe Tex1 is a component of THO/TREX complex, but does not plays important roles in growth and bulk mRNA export from the nucleus.

분열효모에서 TREX-2 복합체의 구성요소인 Sus1이 생장 및 mRNA 방출에 미치는 영향

배수정,윤진호,Bae, Soo Jeong,Yoon, Jin Ho 한국미생물학회 2017 미생물학회지 Vol.53 No.1

Sus1 / ENY2는 진핵생물에 잘 보존된 작은 단백질로 염색사 리모델링과 mRNA 생성과정에 관여한다. Sus1 단백질은 전사 보조활성자인 SAGA 복합체와 핵공과 연관된 TREX2 복합체 등, 핵에 존재하는 2개 복합체의 구성 요소이다. 분열효모 Schizosaccharomyces pombe의 유전체 데이터에서 Sus1의 이종상동체를 찾아 기능을 분석하였다. 4분체 분석 결과 이 유전자는 생장에 필수적이 아니었으나, Sus1 유전자를 결실시키면 낮은 온도에서 생장이 느렸으며, $poly(A)^+$ RNA도 핵 안에 약간 축적되는 표현형을 보였다. 또한 Sus1-GFP 단백질은 주로 핵에 존재하였다. Yeast two-hybrid 분석과 공동면역침전 실험에서 Sus1 단백질은 TREX-2 복합체의 또 다른 구성인자인 Sac3와 상호작용을 하였다. 이와 같은 결과들은 S. pombe의 Sus1 단백질도 역시 TREX-2 복합체의 구성인자로 mRNA 방출에 관여하고 있음을 시사한다. Sus1 / ENY2 is a tiny conserved protein that is involved in chromatin remodeling and mRNA biogenesis. Sus1 is associated to two nuclear complexes, the transcriptional coactivator SAGA and the nuclear pore associated TREX2. In fission yeast, Schizosaccharomyces pombe, ortholog of Sus1 / ENY2 was identified from the genome database. Tetrad analysis showed that the S. pombe sus1 is not essential for growth. However, deletion of the sus1 gene caused cold-sensitive growth retardation with slight accumulation of $poly(A)^+$ RNA in the nucleus. And the Sus1-GFP protein is localized mainly in the nucleus. Yeast two-hybrid analysis and co-immunoprecipitation experiment showed that Sus1 interacts with Sac3, another subunit of TREX2 complex. These results suggest that S. pombe Sus1 is also involved in mRNA export from the nucleus as a component of TREX-2 complex.

중국 패션시장의 성공적 진입을 위한 한,중 스트리트 패션스타일 비교,분석 -서울시와 대련시의 비교를 중심으로-

배수정 ( Soo Jeong Bae ),오현아 ( Hyun A Oh ) 한국패션비즈니스학회 2009 패션 비즈니스 Vol.13 No.4

The main investigation of this thesis is about the comparative analysis of the fashion style preferences in the ages of 20-30 women, according to the style, by researching the area of Dalian and Seoul, represented as outstanding fashion cities in north eastern area. Both taking pictures and recording camcoders were performed at the famous fashion street in Seoul and Dalian. The period of investigation was from 24th of July to 2nd of August 2008. The result of research are as follows. Generally, the casual style was predominant in both area. The jean casual in Seoul was somewhat tidy and conservative, while that in Dalian showed the tendency of boldly exposed their body. In terms of easy casual, T-shirts and mini-tight skirt were preferred in Seoul, while T-shirts and midi-flare skirt was popular in Dalian. In Seoul, the blouse and mini skirt were in vogue, while one-piece dress, blouse and 5/7/9 length pants were prevalent in Dalian, in case of romantic style. The sports casual was relatively low in frequency in both areas, however, it was relatively more popular in Dalian than in Seoul. The frequency of classic style was similar in both areas. The T-shirts/blouse and Chanel-line skirt were preferred in Seoul, while the combination of jacket/shirts and full-length straight pants were preferred in Dalian. The one-piece dress was predominant in feminine style, the combination of mini one-piece dress and shoulder bag prevalent in Seoul, while the combination of Chanel-line one-piece dress designed as boldly exposed body was popular in Dalian, which shows the tendency of sexy, feminine style. The clear contrast or differences of street styles in Seoul and Dalian would become evident by this research. The continuous investigations into the various regions of China would be expected as an important measure for the successful launching into the Chinese fashion market.

퍼지 침입탐지 엔진을 이용한 실시간 침입탐지 대응 모듈 설계

배수정(Su-joung bae),김한섭(Han-sop kim),연현정(Hyun-jeoung yeon),황윤철(Yoon-cheol hwang),이상호(Sang-ho lee) 한국통신학회 2002 한국통신학회 학술대회논문집 Vol.2002 No.11

근대계몽기 문학교육의 형성과 흔적 : 근대 초기 서양문학 수용의 세 국면과무학육

배수정 ( Su Chan Bae ) 한국문학교육학회 2012 문학교육학 Vol.39 No.-

I focused on the interpretation of western literature in Korea in order to investigate vivid aspects of receiving western literature in early modern period. Because interpretation is the sole way to understand western literature for literary education, Until now, though some studied the influence of western literature at various place, hardly anyone had studied the temporal process of interpretation earnestly. As tran slation is a social phenomenon, it develops according as intellectual energy are ripen in one society. In this paper I examined the translation of Pilgrim`sprogess as a missionary text, that of The Count of Monte Cristo as an adapatation, and I enlighted the formation of literary translator in Korea. In Korea, regular translator was formed after 1920s, because Koreans must wait until someone appears who could command Korean and foreigh language efficiently. Translator cannot be educated without long term intellectual investment. For this problem I suggested both the endeavor of scholars who major in western language and the establishment of western classical language institute

대학홍보용(大學弘報用) 의류상품개발(衣類商品開發)에 관(關)한 연구(硏究) -전남대학교(全南大學校)의 사례(事例)를 중심(中心)으로-

배수정 ( Soo Jeong Bae ) 한국패션비즈니스학회 2003 패션 비즈니스 Vol.7 No.1

Recently, the field of university PR(public relations) and UI(university identity) come to be emphasized as a remarkable one because the applicants to the universities are consistently reduced in Korea. The purpose of this thesis is to present a souvenir for university PR which is designed in a clothing commodity, easily accessible to visitors, helping students and university officials to keep a pride to our university. We have designed four kinds of clothing, ie T-shirts, polo-shirts, trousers, and hats, after scrutinizing those of other universities. By making change the length of sleeves and slacks, the four kinds were transformed into eight kinds of clothing commodities. The basic trend of this design is on the trompe l``oeil, with the colors being white, grey and black ones, which are of 100% cotton.

영국(英國) 패션의 원동력(原動力)에 관(關)한 연구(硏究)2 -후세인 샬라얀을 중심(中心)으로-

배수정 ( Soo Jeong Bae ) 한국패션비즈니스학회 2000 패션 비즈니스 Vol.4 No.4

The purpose of this thesis is how to find the way of activating Korean fashion industry, by reviewing the accomplishments of British young designers, Hussein Chalayan, who are contributors to the present peak activities of British fashion. Some results come over this depressive state of Korean fashion might be proposed. Firstly, Korean government should try to direct the Korean fashion associated group to make the unified and effective results in an organized way. Secondly, Korean fashion industries and university-level fashion school should have more intimate relationship and be closely communicated with each other. Also the fashion school should watch their curriculum. and change it gradually to the up-todate one. Thirdly, the Korean new generation designers should do effort to have the highest tailoring technique and artistic good sense. Finally, the designer should have broad range of knowledge for their design. In conclusion, the government, university-level fashion schools, fashion industries and fashion designers should be positively changed and cooperated to do the best and activate Korean fashion.

영국(英國) 패션의 원동력(原動力)에 관(關)한 연구(硏究) (1) -Lee Alexander MacQueen을 중심(中心)으로-

배수정 ( Soo Jeong Bae ) 한국패션비즈니스학회 1998 패션 비즈니스 Vol.2 No.3

대학 수업에서 누적 동료평가 점수를 활용한 성적 산출 방법의 타당성

배수정(Soo Jung Bae),박주용(Joo Yong Park) 한국인지과학회 2016 인지과학 Vol.27 No.2

동료평가 (peer assessment)란 통상 교수자가 주관하는 평가를 학생들로 하여금 서로에 대해 하도록 하는 활동을 가리킨다. 동료평가는 고등교육에서 글쓰기를 훈련시키기 위한 도구 혹은 배운 지식을 적용하거나 확장하는 학습 활동을 위한 도구로 사용된다. Park(2016)은 최근 동료평가를 예습 활동의 한 부분으로 확장하는 방안을 제안하였다. 학생들은 매주의 수업에 앞서 스스로 공부하고, 공부한 내용을 바탕으로 하여 대답할 수 있는 질문에 대해 한 페이지 글을 쓰고 다른 학생들의 글을 평가하였다. 본 연구에서는, 이 시스템을 S 대학의 학부수업에 두 학기에 걸쳐 적용한 결과가 분석되었다. 학생들 간의 채점 신뢰도와, 학생들의 채점 결과와 교수자에 의한 최종 보고서 평가 간의 상관이 분석되었다. 매주의 동료평가에서 학생들이 부여한 점수간의 신뢰도는 그리 높지 않았지만, 이들이 누적된 점수와 교수가 평가한 기말 보고서 점수간의 상관은 두 수업 모두에서 유의미하게 높았다. 논의에서는 이 결과를 바탕으로 대학에서 예습을 위한 동료평가의 결과를 성적에 반영하는 방안의 확장가능성이 다루어졌다. Peer assessment refers to having students, rather than the instructor, make assessments of one another’s work. Peer assessment is often used as a tool to train writing skills or a tool to apply or extend learning in higher education. Park(2016) recently proposed a system which utilizes peer assessment as a part of preparatory activity for college courses. Before weekly class, students studied given material on their own, wrote a one page essay on a given question based on their reading, and assessed the essays of other students. In this study, the system was implemented in undergraduate courses at S University over 2 semesters and the results were analyzed. The reliability of weekly scores given by students was not very high, but the correlation was high between the cumulative scores given by students across weeks and the scores of the end of the term paper assessed by the instructor. Based on these findings, the possibility of utilizing the results of the peer assessments as part of the final grades was discussed.