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박효진(Hyo Jin Park),이찬희(Chan Hee Lee),정준표(Jun Pyo Chung),이관식(Kwan Sik Lee),이상인(Sang In Lee),박인서(In Suh Park),손승국(Seung Kook Sohn),지훈(Hoon Ji),강성웅(Seoung Woong Kang) 대한내과학회 1994 대한내과학회지 Vol.46 No.5
N/A Objectives: As nonorganic, or functional factors play an important etiopathogenetic role in chronic constipation, we have reviewed functional tests on patients with chronic idiopathic constipation. Results of investigation and subsequent proper treatment are suggested. Methods: Clinical assessment, colonic transit, defecogram, anorectal manometry and pelvic floor electrophysiologic tests were performed in 30 patients with chronic idiopathic constipation, Results: 1) The ratio of male to female was 1:4, and the mean age was 48.2 years. Primary complaints were incomplete evacuation (83.3%), abdominal fullness (70.0%), abdominal pain (70.0%), rectal bleeding (43.3%), nausea (33.3%), tenesmus (33.3%) and dysuria (20.0%). Hemorrhoids and melanosis coli were present in 70.4% and 11.1% of the patients respectively at colonoscopy. The types of personality using the Minnesota Multiphasic Personality Inventory showed somatization 50.0% and psycho- physiological reaction 41.7%. 2) Colonic transit studies identified three patterns: normal transit 38.9%, colonic inertia 22.2%, pelvic outlet obstruction 16.7%, and mixed type 22.2%. The mean transit time of total colon was 56.4±5.0 hr. in colonic inertia and mixed type. 3) Defecogram revealed rectocele 77.8%, incomplete evacuation 48.1%, paradoxical contraction of puborectalis 40.7%, rectal intussusception 25.9%, parietal rectal rigidity 11.1%, and excessive pelvic floor descent 11.1%. 4) The mean minimal sensory volume, anal sphincter length, maximum resting and squeeze anal pressure was 47.9±17.5 ml, 3.9±0.9 cm, 104.3±17.9mmHg and 156.4±15.0mmHg respectively. The anorectal inhibitory reflex was intact in all patients. 5) Electrophysiologic studies suggested pudendal neuropathy in 5 patients (27.8%). 6) The patients were treated by drug therapy 83.3%, biofeedback therapy 10.0% and operation 6.7%. Conclusion: From the above results, systematic diagnostic evaluation and proper treatment for the patients with chronic idiopathic constipation in view of functional motility disorder are required and treatment can be helpful particularly when directed by a multidisciplinary team approach.
Helicobacter pylori 에 대한 혈청 IgG 항체의 양성율 및 혈청 Pepsinogen 과의 상관관계
박효진(Hyo Jin Park),이병권(Byoung Kwon Lee),정준표(Jun Pyo Chung),조현근(Hyeon Geun Cho),이상인(Sang In Lee),박인서(In Suh Park),손영모(Young Mo Sohn),이창훈(Chang Hoon Lee),송경순(Kyung Soon Song) 대한내과학회 1995 대한내과학회지 Vol.48 No.1
N/A Objectives: This study was designed to estimate the prevalence of Helicobacter Pylori infection in a healthy population in Korea and correlate between H. Pylori infection and serum pepsinogen levels as markers of gastritis and atrophic gastritis. Methods: We collected sera obtained form 104 children and 173 adult who had no gastrointestinal symptoms and measured specific IgG antibodies against H. Pylori by Bio-Rad G. A. P test. Serum pepsinogen 1 and 2 concentrations were determined by radioimmunoassay. Results: 1) The frequency of H. Pylori infection increased with age and was more than 80% over age 40. 2) Serum pepsinogen 1 and 2 concentrations in the healthy population were increased with age, while the serum pepsinogen 1/2 ratio decreased. 3) There were no significant statistical differences between the titre of specific IgG antibodies against H. Pylori and serum pepsinogens. Conclusion: The data from this study suggested that the prevalence of Helicobacter Pylori infection increased with age and serum pepsinogen levels were related to the presence or absence of H. Pylori infection. We conclude that H. Pylori infection is one of the factors which helps develop atrophic gastritis, the precursor lesion of gastric cancer.
박인서(In Suh Park),강진경(Jin Kyung Kain),김충배(Choong Bai Kim),박효진(Hyo Jin Park),문병수(Byung Soo Moon),이천균(Chun Kyun Lee) 대한소화기학회 1997 대한소화기학회지 Vol.29 No.5
Three patients with epiphrenic diverticula were reviewed with foci on esophageal dysfuntion and its relation to treatment. All cases were identified by bariurn esophagogram and confirmed by endoscopy. Manoetric studies of esophagus documented as diffuse esophageal spasm-like disorder in 1 case, and nonspecific motor disorder in 2 cases. One case was managed surgically, and the other 2 were treated conservatively. We found that epiphrenic diverticulum were associated with esophageal motility disorders. Treatment should be considered to focus on associated motility disorders as well as a diverticulum. (Korean J Gastroenterol 1997;29:687-693)
박인서(In Suh Park),문영명(Young Myoung Moon),정재복(Jae Bock Chung),이상인(Sang In Lee),김원호(Won Ho Kim),이관식(Kwan Sik Lee),정현주(Hyeon Joo Jeong),박효진(Hyo Jin Park),정준표(Jun Pyo Chung),박경아(Kyung Ah Park),남문석(Moon Suk 대한소화기학회 1993 대한소화기학회지 Vol.25 No.5
N/A Melanosis coli associated with ingestion of anthraquinone compounds in laxatives is due to accumulation of macrophages containing brown lipofuscin-like pigments in the lamina propria. We analyzed the clinical, endoscopic, and pathologic findings and colonic motor functions of melanosis coli and performed electronmicroscopic study to know the ultrastructural changes of neural elements. We studied 13 cases (mean age 48.1 +- 18.5 years, male to female cases 6:7). The vegetable laxatives containing anthraquinone derivatives, aloe or bisacodyl were used mainly and the mean duration of laxative abuse was l.5 +- 1.2 years. Endoscopically, dark brownish mucosal disoloration showed polyhedral forms divided by fine striae of lighter color. Melanosis was more intense in the more oral part of the bowel. Pathologically, no relationship was found between grade of melanosis and kind of drugs, daily dose, or durat.ion of addiction. Ultrastructural features on nerve structure were ballooning of axon. reduction of nerve specific cell organelles, and increased lysosomal activity. The alterations of these neural elements are assumed to he associated with impaired colonic motility. In conclusion, vegetable laxatives such as aloe, seem to be an important causes of melanosis coli in Korea. melanosis coli have a tendency to damage nerve fibers. We should avoid laxative abuse in order to prevent pragressing to cathartic colon.
박효진(Hyo Jin Pack),김범수(Pum Soo Ki m),이정운(Jung Woon Lee),박인서(In Suh Park) 대한소화기학회 1995 대한소화기학회지 Vol.27 No.3
N/A Background/Aims: Esophageal acid clearance is an important mechanism protective against the development of reflux esophagitis. Acid clearance from the esophagus after gastro-esophageal reflux depends on two important mechanisms: esophageal peristalsis to return the displaced gastric content to the stomach and swallowed saliva to neutralize the residual acid that coats the esopha- gea1 mucosa. The present study aims to investigate acid clearance and determine the contributions of esophageal peristalsis, salivation, and gravity. Methods: We performed the acid clearance test, ambulatory 24 hour esophageal pH study, esophageal manometry and saliva study in 16 consecutive patients with reflux esophagitis, and then compared them with normal controls. Results: The clearance of acid instilled into the esophagus was markedly delayed in patients with reflux esophagitis as compared with controls(p0.05). There was a trend towards a lower peristaltic amplitude in patients with reflux esophagitis, but this was statistically not significant. Of the motor events analyzed, there were simultaneous contractions in 4 patients(25.0%), poor wave progression in 4 patients(25.0%), and non-transmitted contraction in 2 patients(12.5%). In patients with reflux esophagitis, the number of reflux episodes, the mean number of reflux episodes greater than 5 minutes, and the percentage of time when the pH was less than 4 were significantly increased compared with controls(p <0.05). The basal and stimulated salivary pH and concentration of bicarbonate in patients with reflux esophagitis did not show a significant difference compared with controls. Conclusions: We found a significant impairment of acid clearance in patients with reflux esophagitis, and some alterations in esophageal peristalsis but no change in salivary functions. (Korean J Gastroenterol 1995;27:275 - 282)
박효진 ( Hyo Jin Park ),지상원 ( Sang Won Ji ),임정현 ( Jung Hyun Lim ),이상인 ( Sang In Lee ) 대한소화기기능성질환·운동학회 2003 Journal of Neurogastroenterology and Motility (JNM Vol.9 No.1
목적 : 실험적 대장염 쥐의 장 근육절편을 이용한 실험상 근육 장력이 감소되고, 궤양성 대장염환자 등의 염증성 장질환에서 대장운동 및 통과 장애가 보고되었다. 이에 저자들은 기니 픽에게 trinitrobenzene sulphonic acid (TNBS)로 유도한 실험적 대장염 모델을 만든 후, 시간 경과에 따른 염증 정도를 관찰하고 대장 근육 장력 및 대장통과시간의 변화를 알아보고자 하였다. 대상 및 방법 : 기니 픽 36 마리를 대상으로 TNBS 0. Background/Aims: Trinitrobenzene sulphonic acid (TNBS)-induced colonic inflammation in rat alters colonic motor function. The aims of this study were to investigate the effect of TNBS-induced colitis on the colonic motor function of a guinea pig along the
박효진 ( Park Hyo-jin ),박윤희 ( Park Yoon-hee ) 국제어문학회 2015 국제어문 Vol.0 No.64
본 연구는 노르트와 허만스의 고유명사에 관한 이론에 기반하여 한국 문학작품에서 작가의 의도가 담긴 `동기가 부여된 고유명사`가 영문으로 번역될 때, 그 의도와 의미가 제대로 전달되는지를 살펴보고 그 대안을 제시한다. 지금까지의 한영 문학번역의 실태를 보면 고유명사의 경우 음차번역이 당연시되고 있는 실정인데, 의미적 함축이 용이한 한자어로 된 한국 소설의 고유명사는 영어로 번역될 때 그 의미의 설명이 어떤 형식으로든 반드시 이뤄져야 할 것으로 본다. 따라서 본 연구는 대다수의 등장인물 이름이나 고유명사, 지칭어 등이 영어 번역문에서 의미가 손실되지 않고 제대로 전달되는 지의 여부를 몇몇 한국 현대 단편 소설 텍스트와 영어 번역 텍스트의 대조 분석을 통해 확인한다. 텍스트 분석을 통해 한자어 기반의 작명 문화가 반영된 한국 문학 작품 내 등장인물의 이름이나 별명, 지칭어가 영어 번역문에서 그 의미가 손실되거나 제대로 전달되지 않았다고 판단되는 경우, 이를 보완하면서 그 의미를 목표텍스트(Target Text: TT) 독자에게 전달할 수 있는 유용한 대안이 무엇인지 모색하는 것이 본 논문의 목적이다. Based on the proper noun-related theories of Nord (2003) and Hermans (1988), this study aims to examine whether the intended meanings of `loaded proper nouns` appearing in Korean literature are properly delivered through translation into English. Another goal of this research is proposing an alterative to adequately transfer those `loaded proper nouns` into English text. Given the translation practices of Korean literature into English so far, the transliteration strategy has been taken for granted. For Sino-Korean proper nouns facilitating meaningful implication shown in Korean literature, however; their intended meanings are considered to be necessarily explained in any way as translated into English. In this regard, this study firstly examines whether most characters` names and proper nouns of Korean literature are transferred into English version without any loss of meaning through the comparison analysis of several modern Korean short story text and their translated English text. And then in case the Korean loaded proper nouns reflecting the naming culture established on Sino-Korean words are not properly transferred or their own meanings are missed in the English version, a useful alternative enabling to deliver the intended meanings to the Target Text (TT) readers is suggested through this research.
일개 종합병원 복강경 위절제술 환자의 표준진료지침 적용효과
박효진(Hyo-Jin Park),박종(Jong Park),류소연(So-Yeon Ryu),최성우(Seong-Woo Choi) 한국콘텐츠학회 2016 한국콘텐츠학회논문지 Vol.16 No.9
본 연구는 새롭게 개발된 복강경 위절제술의 표준진료지침(Critical pathway, CP) 적용효과를 분석하기 위해 수행되었다. 연구대상은 전라남도에 소재한 C병원 위장관클리닉에서 위암으로 진단받고 복강경 위아 전절제술을 시행하고 퇴원한 20세 이상의 성인 환자로, 실험군은 2008년 10월부터 2009년 9월까지 CP를 적용하여 복강경 위아전절제술을 시행한 환자 102명으로 하였고, 대조군은 2007년 9월부터 2008년 9월까지 CP를 적용하지 않고 복강경 위아전절제술을 시행한 환자 63명으로 하였다. 본 연구결과 퇴원시 통증에서는 CP적용군이 비적용군보다 퇴원 당일 통증이 있는 경우가 0.07배 낮았다(Odds ratio [OR], 0.07; 95% Confidence interval [CI], 0.03-0.21). 총 재원일수는 CP적용군에서는 평균(표준오차)은 8.95(1.33)일, 비적용군에서는 평균 10.69(4.04)일로 유의한 차이를 보였고(p<0.001), 수술 후 재원일수 또한 CP적용군이 평균 7.16(0.94)일, 비적용군이 평균 8.79(3.90)일로 통계적으로 유의한 차이(p<0.001)를 보였다. 본 연구 결과 복강경 위절제술에 대한 CP의 적용은 퇴원시 통증감소, 총 재원일수 및 수술 후 재원일수를 단축시키는 효과를 보였다. This study is aim to investigate how applying a critical pathway(CP) to stomach cancer patients affects their recovery and treatment. The subjects were 165 patients over the age of 20 who were diagnosed with stomach cancer at the gastrointestinal clinic of C hospital and who underwent laparoscopic subtotal gastrectomy. The case group inclueded 102 patients who underwent laparoscopic subtotal gastrectomy with applying the CP from October 2008 to September 2009. The control group included 63 patients who underwent laparoscopic subtotal gastrectomy without applying the CP from September 2007 to September 2008. Pain at the time of discharge was significantly lower in the CP applicated group than in the non-applicated group (Odds ratio [OR], 0.07; 95% Confidence interval [CI], 0.03-0.21). The CP applied group was significantly lower than non-applied group in total hospitalization days (CP applied group: 8.95[1.33], non-applied group: 10.69[4.04], p<0.001) and in postoperative hospitalization days (CP applied group: 7.16[0.94], non-applied group: 8.79[3.90], p<0.001). In conclusion, application of a critical pathway to laparoscopic subtotal gastrectomy reduced pain at the time of discharge, total hospitalization days and postoperative hospitalization days.