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김영훈,김진호,박영태,이창홍,최인석 대한내과학회 1986 대한내과학회지 Vol.31 No.4
Bicarbonate secretion by the stomach may play a role in gastric mucosal protection, but there is limited information on the amount of bicarbonate secretion. We have therefore examined bicarbonate secretion in 9 normal adults and in 9 patients with duodenal ulcer, using a recently validated method utilizing measurements of gastric juice volume, hydrogen ion concentration and osmolality of gastric juice and plasma. The results are as follows: 1) In 9 healthy subjects, basal gastric bicarbonate secretion rate was 1.5±0.2 mmol/hr(mean±1 SE). After pentagastrin injection(6 mg/kg), the gastric bicarbonate secretion rate increased to 2.5±0.7 mmol/hr but the difference was not significant. 2) In 9 patients with duodenal ulcer, basal gastric bicarbonate secretion rate and gastric bicarbonate secretion after pentagastrin injection were 1.9±0.4 mmol/hr respectively. The difference was not significant, either. 3) The gastric bicarbonate secretion rates were not significantly different in the two groups either basally or after pentagastrin injection.
소장내용물의 위내역류 및 위내용물 배출시간에 관한 연구
김진호,박승철,이형호,안일민,박영태,김열흥,이창흥 대한내과학회 1986 대한내과학회지 Vol.30 No.2
Radionuclide enterogastric scintigraphy was done with (99m)Tc-DISIDA and (111)In-DTPA in 35cases; control group 5, gastric ulcer group 6, subtotal gastrectomy with Billroth g group 5, and functional gastrointestinal disorder group with or without grossly mixed bile in the gastric juice 19 cases. The results were: 1) Enterogastric reflux was very significantly increased in the subtotal gastrectomy with Billroth II group (p$lt;0, 001), 2) Gastric emptying was significantly delayed in the functional gastrointestinal disorder groups with or without grossly mixed bile (p$lt;0.05, p$lt;0. 001). 3) Enterogastric reflux was not significantly increased in the gastric ulcer group. 4) Enterogastric reflux was not significantly different between the functional gastrointestinal groups with or without grossly mixed bile in the gastric juice. 5) Inverse correlation between the gastric emptying indices and the enterogastric reflux indices was not proved (r=-0.37).