유산균을 이용한 대두 발효 추출물이 면역계 활성에 미치는 영향

박병두,김혜자,Park, Byung-Doo,Kim, Hye-Ja 대한예방한의학회 2012 대한예방한의학회지 Vol.16 No.3

Objectives : NK cells are spontaneously cytotoxic lymphocytes. These are not only important parts in the first line of defence against bacterial and viral infections of outside, but they may also play a critical role in chronic viral diseases. NK cells kill their targets spontaneously, without the need for prior sensitization and class I MHC restriction by the regulation of cytolytic functions and secretion of a variety of cytokines, such as interleukin-12(IL-12), MCP-1, IL-6, TNF-${\alpha}$, IFN-${\gamma}$. In addition, macrophage and NK cells cooperate through the production of cell mediates. These cooperation and modulation are one of major factors to prevent for evading immune surveillance of cancer. Hence, it could be assumed that if any candidate to enhance activities of macrophage and NK cell, it is considered as a potentially useful agents against cancer. Methods : In our study, to investigate effect of fermented soybean extracts by Lactic acid bacteria (SFE, soybean fermented extracts) work on intestinal immune cell to maintain general immune modulating and anti-cancer activity. We analyzed NK cytotoxicity assay and gene expressions of cytokine related with macrophage and NK cell activity. Results : In vitro experiment, SFE was verified as safety material for cell toxicicty to tumor cell strain without any toxicity of tumor growth inhibition and various cell strain. Effects of macrophage activity stimulating directly by SFE measured induced cytokine. The studies showed that IL-12 production by stimulation of SFE depended on concentration from 0.16mg/mL to 0.63mg/mL with non toxicity to cell, and it was the best activity at 0.63mg/mL. Besides, the effective concentration of SFE producing TNF-${\alpha}$ is similar to IL-12, but it was the best activity at 1.25mg/mL. The level of MCP-1, IL-6 and IFN-${\gamma}$ depended on concentration from 0.16mg/mL to 10mg/mL, IFN-${\gamma}$ showed the best activity at the effective concentration of 0.63mg/mL. With the result of NK cell activity measurement, the spleen cell of mouse injected SFE had 1.5 times higher killing effect than non injected cell. Conclusions : The result of this studies is that Soybean fermetated extracts(SFE) has possibility to immune aided material for the function not only inhibition of microbial infection to macrophage but also activity of adaption immune and cellular immune system.

경찰공무원의 피로가 직무태도에 미치는 영향에 관한 연구

박병두(Park, Byung-Doo) 한국민간경비학회 2008 한국민간경비학회보 Vol.12 No.-

최근의 치안환경은 범죄의 양적․질적 증가, 인적․물적 자원의 제한, 시민의 안전에 대한 욕구와 치안서비스에 대한 기대수준이 향상됨에 따라 경찰은 효과적이고 능동적으로 대처해기 위해 업무가 지속적으로 증가하고 있다. 피로에 지친 경찰공무원들에게 시민들에 대한 질 좋은 서비스를 기대하는 것은 어려울 것이며, 결국 시민들의 불만을 야기하게 될 뿐이다. 따라서 경찰공무원의 피로 문제를 보다 적극적으로 대처하고 부작용을 최소화하기 위해서는 보다 실증적이고 체계적인 연구가 필요하다고 본다. 따라서 이 연구는 경찰공무원의 피로 원인요인과 경찰공무원이 지각하는 피로도, 그리고 직무태도에 대한 영향관계을 규명함으로써, 경찰공무원의 삶의 질을 향상시키고 나아가 국민들에게 제공되는 치안서비스의 질을 향상시키는데 기여하고자 한다. The fatigue of the police officers, such as the increase of demanded conditions, are increasing by the change of environment of inside and outside of the police. The fatigue is very critical problem among police officers along with the productivity because of newly required skill with a high intensity of work and complicated human relationship with a tough working environment. Police officers unable to solve the problem of fatigue created by their tasks has high possibility of jeopardizing their associates and citizens as well as themselves. Furthermore, fatigue can also have not good effects on police organization in various aspects. Accordingly, the problem of police officers's fatigue has significant meanings especially on effectiveness of the organization. So, this study is performed to provide implications for police officer' life quality grows by grasping not only influence that fatigue has on job attitudes, and whole relation among fatigue, the antecedents of fatigue and job attitudes that are consequences of fatigue.

민간 스포츠시설 산업의 실태와 발전방안

전호문 ( Ho Mun Jun ),박병두 ( Byung Doo Park ),박성수 ( Sung Su Park ) 한국스포츠산업경영학회 2009 한국스포츠산업경영학회지 Vol.14 No.3

본 연구의 목적은 우리나라 민간 스포츠시설 산업의 ‘현황과 전망’, ‘인력’, ‘효과’, ‘정부, 산·학 기관과의 관계’, ‘법과 제도’에 대한 조사, 분석’을 통해 민간 스포츠시설 산업의 폭넓은 이해와 방안을 마련하는데 있다. 연구를 위해 민간 스포츠시설 산업의 운영현황 산업 발전을 위한 전략 및 방안에 현실적인 정보를 제공할 수 있는 민간 스포츠시설 산업 관련 전문가 100명에게 공문을 보냈으나, 관심 있는 42명이 참여 하였으며 최종적으로는 민간 스포츠시설 산업의 발전 방안을 위해 현실적이고 성실하게 답변이 이루어진 20부를 사용 하였다. 분석결과 현황과 전망과 관련하여 첫째, 단일종목보다 복합형 민간스포츠시설 사업의 운영이 많은 것으로 나타났다. 둘째, 국내경기 불황으로 시설 이용 회원 감소, 시설 운영관리비 증대에 따른 경영난이 가장 많이 나타났다. 셋째, 동종업계의 공급과잉현상 및 공공스포츠시설과의 가격경쟁이 가장 큰 발전 저해 장애요인으로 나타났다. 인력에 관한 내용에 대해 첫째, 시설관리, 경영, 홍보, 판촉의 능력과 기술을 갖춘 전문 스포츠시설 관리자, 스포츠시설매니지먼트, 스포츠마케팅 분야의 전문인력이 필요하다고 나타났다. 둘째, 전문인력은 필요인력에 50%미만이 공급되고 있다고 나타났다. 효과에 관한 내용에 대해 첫째, 시설사업홍보를 위해 실시했던 각종광고가 산업 개발을 위해 실행했던 방법, 전략 중 가장 많이 나타났다. 둘째, 마케팅을 통한 회원모집행사 방법, 전략이 효과가 없었던 것으로 가장 많이 나타났다. 정부, 산·학기관의 역할에 관한 내용에 대해 첫째, 민간스포츠시설사업의 관리, 지원할 전담부처 설립과 국민체육진흥기금을 통한 민간 스포츠시설 산업 지원의 역할이 가장 필요하다고 나타났다. 둘째, 산·학 간의 협력이 잘 이루어지고 있다고 나타났다. 법과 제도에 관한 내용에 대해 첫째, 국민체육진흥법, 체육지도자 연수 및 자격검정에 관한 규칙이 산업발전에 도움이 되고 있다고 나타났다. 둘째, 체육지도자 연수 및 자격검정에 관한 규칙이 개선되어야 할 제도라고 나타났다. 셋째, 산업 발전을 위해 체육시설설치 이용법, 국민체육진흥법이 개선되어야 한다고 나타났다. This study has its purpose on figuring it out to the broad understanding and plan of civilian sport-facilities through researches and analyses about Korean civilian sport-facilities industry; especially, centering into its ``current status and prospect``, ``human power``, ``effectiveness``, ``the relationship among the Governmental, industrial, and academic organizations`` and ``the laws and systems``. The results on the current status and prospect are as follows; first, the operation of multi-civilian sport-facilities is more frequent than the operation of single event facilities. The Second is the operation difficulty of sport-facilities industry. It is the most frequent case to the operation difficulty by increasing the operation and management expenses about the facilities and by decreasing the number of using members because of Korean economic depression. Thirdly, the greatest obstacle for its development is to the excessive supply phenomenon of the same sort of business circles. As for the field of a human power, first, the result indicates the necessity of specialists who have capability and skill for a facility management, administration, advertisement, and sales promotion in the field of professional sport-facilities management, sport-facilities management, and sports marketing. Secondly, the supply for the specialists is less than 50% of the necessary human power. In case of the contents on the effectiveness, first, various advertisements for public relations has been the most frequent used among the ways and strategies to have carried out for industrial developments. Secondly, the result expresses that it is no effectiveness to the member recruiting events through marketing. On the role of the Governmental, industrial, and academic organizations, first, the result appears that it is the most necessary to the supporting role of civilian sport-facilities industry by the establishment of a fully responsible department for managing and supporting to civilian sport-facilities business as well as through the National Athletic Promotion Fund. Secondly, it could be said that the cooperation between industry and academy has well carried out because the marketing has been greatly created by the agreement with the companies of sports-supplies. Finally, as for the laws and systems, first, the result expresses that it has been helpful to the industry development to the Law of National Athletic Promotion and the Regulation on the Training and the Qualifying Probation for Physical Director. Secondly, on the other hand, the result points out this regulation to need to be improved. Third, the result also points out the Law of National Athletic Promotion and the Law of the Installation of Athletic Facilities to need to be improved.