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박동재 ( Park Dong Jae ),박지영 ( Park Ji Yeong ),이석종 ( Lee Seog Jong ),김도원 ( Kim Do Won ),정상립 ( Jeong Sang Lib ),김선주 ( Kim Seon Ju ) 대한피부과학회 2003 대한피부과학회지 Vol.41 No.9
BCG(Bacillus Calmette-Guerin) is a vaccine from living attenuated Mycobacterium bovis which produces resistance to tuberculous infection. It induces specific and nonspecific dermatologic complications on the vaccination site or out of the site. The specif
위암에서 Cyclooxygenase - 2 와 Inducible Nitric Oxide Synthase 의 발현
박동일(Dong Il Park),이종철(Jong Chul Rhee),손희정(Hee Jung Son),송상용(Sang Yong Song),김영호(Young Ho Kim),이풍렬(Poong Lyul Rhee),김재준(Jae J . Kim),백승운(Seung Woon Paik),최규완(Kyoo Wan Choi),손태성(Tae Sung Son) 대한소화기학회 2001 대한소화기학회지 Vol.38 No.3
Background/Aims: It has been expected that chronic expression of cyclooxygenase-2(COX-2) and inducible nitric oxide synthase(Inos) may play an important role in gastric carcinogenesis. The purpose of our study was to investigate the role of COX-2 and Inos Mrna expression in gastric carcinogenesis and the correlation between the expression of COX-2 and Inos Mrna in patients with gastric cancer. Methods: Twenty-three gastric carcinoma tissue specimens and their adjacent normal mucosa specimens were obtained from surgical resection. The expression of COX-2 and Inos Mrna were examined by comparative reverse transcriptase-polymerase chain reaction. Results: COX-2 and Inos Mrna were expressed significantly higher in gastric cancer tissues than in adjacent normal tissues. There was a significant correlation between the level of COX-2 and Inos Mrna in carcinoma tissues. There was no significant correlation between the level of COX-2 or Inos Mrna expression and clinicopathological parameters such as tumor size, depth of invasion, differentiation, Laurens classification, lymph node metastasis, perineural and vascular invasion in these patients. Conclusions: The expression of COX-2 and Inos may be one of the factors that contribute to the early stage of gastric carcinogenesis. (Korean J Gastroenterol 2001;38:161-168)
중증 궤양성 대장염에서 치료 성적의 예측인자와 Cyclooxygenase - 2 발현과의 관계
박동일(Dong Il Park),김영호(Young Ho Kim),성인경(In Kyung Sung),이용육(Yong Wook Lee),이준행(Jun Haeng Lee),김지은(Jee Eun Kim),현재근(Jae Geun Hyun),장재권(Jae Kwon Jang),손희정(Hee Jung Son),이풍렬(Poong Lyul Rhee),김재준(Jae J . K 대한소화기학회 2001 대한소화기학회지 Vol.38 No.1
Background/Aims: Percutaneous endoscopic gastrostomy (PEG) has been widely performed for patients who require prolonged tube feeding support. A retrospective study was conducted to evaluate the complications of PEG and determine the predictors of wound infection. Methods: Medical records of 144 cases of PEG that was per- formed between January 1996 and June 2000 were reviewed to examine the types and frequency of complication, difference in wound infection rates according to age, sex, and underlying diseases. We also analyzed the effects of antibiotics prophylaxis on wound infection and the result of culture from wound infection site. Results: In 28 of 144 PEG cases (19.4%), several complications developed after procedure. Wound infection was the most common complication and occurred in 22 of 144 cases (15.3%) and Pseudomonas aeruginosa was the most common pathogenic microorganism. Other complications included bleeding from gastrostomy site, stomal leaks, and gastroesophageal reflux. There was no statistical difference in wound infection rates according to underlying diseases and antibiotics prophylaxis. However, wound infection developed more frequently in diabetes patients (p<0.05). Old age and underlying diabetes were predictors for developing wound infection after PEG in multiple logistic regression analysis. Conclusions: Old age and DM can be predictors of wound infection associated with PEG. (Korean J Gastroenterol 2001;38:23-28)
박동재 ( Dong Jae Park ),오병민 ( Byung Min Oh ),이석종 ( Seok Jong Lee ),나건연 ( Gun Yeon Na ),김도원 ( Do Won Kim ),정상립 ( Sang Lip Chung ),곽은경 ( Eun Kyung Kwak ) 대한피부과학회 2003 대한피부과학회지 Vol.41 No.4
Neuroendocrine carcinoma is known to have features of neuroendocrine and epithelial differentiation through immunochemical and biochemical investigation and Merkel cell carcinoma is a rare primary malignancy of the skin belonging to the broad spectrum of tumors of the neuroendocrine system. Small cell carcinoma of uterine cervix, also a kind of neuroenodcrine carcinoma, is rarely reported and it is much more exceptional in the world that cervical carcinoma metastases to distant skin. Further more this may be the first case of a uterine neuroendocrine carcinoma metastasizing to the skin in Korean medical literature. We report a case of 74-year-old woman who presented with a somewhat fixed subcutaneous nodule measuring 2.5 ㎝ × 0.8 ㎝ on the left side of forehead. A biopsy of the nodule revealed a poorly differentiated carcinoma under the muscle without involvement of upper structures and it showed neuroendocrine differentiation by immunohistologic studies. Before appearing as cutaneous manifestation 2 months ago, she had showed a history of abnormal vaginal bleeding and diagnosed as a cervical neuroendocrine carcinoma, especially small cell carcinoma histologically. (Korean J Dermatol 2003;41(4) : 484-488)
면도절제술 후 귀걸이 압박요법으로 자가 치료한 귓불 켈로이드 4예
박동재 ( Dong Jae Park ),차영창 ( Young Chang Cha ),이석종 ( Seok Jong Lee ),나건연 ( Gun Yoen Na ),김도원 ( Do Won Kim ),정상립 ( Sang Lip Chung ) 대한피부과학회 2002 대한피부과학회지 Vol.40 No.11
Keloid is a benign proliferative growth of dermal collagen which extends beyond the original wound. Although there are several available methods of treatment including intralesional corticosteroid injection, cryotherapy, surgical excision, laser therapy, pressure, radiotherapy, interferon-α injection and so on, no effective modality to prevent the recurrence of keloids may be present. We have done shaving excision of keloids on the earlobes of 4 patients and then recommended earring made to order for home compression over 4∼5 months therapy with no recurrence for 1∼3 years. It is suggested that compression therapy with earring following shaving excision may be proven to be not only a simple but effective method for prevention of recurrence after removal of keloid on the earlobe.
박동철(Dong-Chul Park),정훈(Hun Chung),김태성(Tae-Sung Kim) 대한검도학회 2005 대한검도학회지 Vol.21 No.1
현재, 한국 검도의 기량과 그 수준은 국제검도연맹 가맹국가 중 최강의 검도국으로 발전하였다. 세계검도계를 이끌어가고 선도해 가기 위해서 한국검도문화를 더욱 발전시켜가야 하며, 한국검도의 오랜 숙원인 세계검도선수권대회에서 정상에 우뚝 서는 것이 우리 검도인들의 과제라 할 것이다. 그러기 위해서, 다시 한번 한국검도문화를 다시 돌아보고, 21세기 한국검도가 한층 발전하고 성문화된 검도수련문화에로의 전환이 요구되어져야 한다. 먼저, 師弟同行의 실천적 교육을 통한 신체로 인식하고, 신체로 생각하는 살아있는 身體知의 습득을 위한 수련문화에로 발전함으로써, 정신과 신체가 조화를 이루는 성숙된 자아실현으로 발전되는 수련문화가 요구되어지고 있다. 그리고, 기나긴 검도수행의 길로써 자기 검도의 깊이를 쌓아가고 보다 검도의 한판의 기준이 되는 기검체 일치가 되기 위해서는 기본이 충실한 수련문화가 요구되어지고 있다. 기본이 충실한 검도수련은 수련자 자신이 일도양단이란 보다 검도디운 개념을 갖게 하고, 보다 크고, 아름다운 검도로 발전하는 근원이 되기 때문이다. 한국겸도의 미래를 결정하는 문화적 문제로서, 심판력을 높이는 심판문화에로 발전이 되어야 하는 것이다. 유효격자가 되는 한판의 판정을 보다 공정하고 정확하게 판정하는 심판력의 향상은 수련자의 겸도에 대한 태도, 자세 등 장래 검도의 방향성을 결정하며, 더 나아가서는 우리나라 검도의 국제적 위상을 결정하기 때문이다. Now, the skills and levels of Korean Kendo has developed into one of the best among nations associated with International Kendo Federation. In order to maintain the lead in the world of international Kendo, it is necessary to develop a unique culture for Korean Kendo and to mount a top of International Kendo Competition, which Korean Kendo people have had a great deal of enthusiasm to win. To this end, reviewing the current Kendo culture in Korea should be a priority, and it is essential to transform the present status into a written and matured Kendo practice culture. Accordingly, followings are recommended for the betterment of Korean Kendo. First of all, by educating a teacher-student accompaniment, we should develop a practice culture for experiencing a status of physical knowledge. Also, we need to develop a matured culture where Kendo people have opportunities to balance their mind and physical needs. Second, by practicing longer and longer. we should try to accumulate the depth of our own Kendo experience and to concentrate on the fundamentals of Kendo performance. which are characterized into 'unification of mind. sword and body'. More focus on the basics is likely to be developed into a right Kendo culture where Kendo people understand true value of practicing Kendo. Finally, as one of the serious issues in Korean Kendo, developing fairness of officials in Kendo competitions should be considered to create a positive jury culture which has ramifications to determine Kendo people's practice attitude, future directions and international status of Korean Kendo and status of Korean Kendo in the globe.
감염과 관련된 위점막 조직의 Glutathione에 관한 연구
박동균 ( Dong Kyun Park ),김은수 ( Eun Soo Kim ),홍순홍 ( Soon Hong Hong ),정문기 ( Moon Gi Chun ),권오상 ( Oh Sang Kwon ),김선숙 ( Sun Suk Kim ),구양서 ( Yang Suh Kwon ),김유경 ( Yu Kyun Kim ),최덕주 ( Duck Joo Choi ),박현철 ( Hy 대한소화기학회 2002 대한소화기학회 춘계학술대회 Vol.2002 No.-
<목적> Helicobacter pylori(H. pylori)에 의한 위점막 손상은 H. pylori에 의해 활성화된 염증세포의 산소 유리기 생성 및 자극과 관련이 있다고 알려져 왔고 최근에는 H. pylori 자체에서도 산소 유리기가 발생한다는 연구가 있다. 본 연구에서는 updated Sydney system을 이용한 grading 과 산소 유리기를 간접적으로 측정할 수 있는 glutathione(GSH)의 농도를 분석하여 위점막의 산소유리기와 H