檢査試驗에 對한 小考

朴管鎭 대한토목학회 1965 대한토목학회지 Vol.13 No.2

항산화제와 유전자치료의 병합요법: 혈관성 발기부전 백서모델에 미치는 영향

박관진,송상훈,김수웅,백재승 대한남성과학회 2006 The World Journal of Men's Health Vol.24 No.3

An Evolution of Orchiopexy: Historical Aspect

박관진,최황 대한비뇨의학회 2010 Investigative and Clinical Urology Vol.51 No.3

The history of treatment for cryptorchidism dates back more than 200 years. This review is intended to highlight some historical aspect that led us to our current surgical treatment of this condition. The medical and historical surgical literatures pertaining to cryptorchidism were reviewed. Data sources were PubMed, Embase, conference proceedings, and bibliographies. No language, date, or publication status restrictions were imposed. The study of cryptorchidism began with the anatomical descriptions of Baron Albrecht von Haller and John Hunter. Attempts at surgical correction of the undescended testis began in the early 1800s, culminating in the first successful orchiopexy by Thomas Annandale in 1877. Max Schüller, Arthur Dean Bevan and Lattimer contributed to the establishment of current techniques for standard orchiopexy. Later, laparoscopy, high inguinal incision (Jones’ approach) and scrotal approach were added to the list of current orchiopexy.

당뇨병성 발기부전

박관진,백재승 대한남성과학회 2009 The World Journal of Men's Health Vol.27 No.3

Purpose: To understand the pathophysiology of diabetic erectile dysfunction (ED) and to review the current strategies against diabetic ED. Materials and Methods: A systematic search was performed of MEDLINE databases to obtain articles pertaining to the pathophysiology and management of diabetic ED. Results: No single etiology has been identified as the principal cause of ED. Studies from non-penile tissue have indicated hyperglycemia-induced mitochondrial superoxide production activates the four damaging pathways by inhibiting glyceraldehyde-3-phosphate dehydrogenase (GAPDH). It appears that these mechanisms provide molecular basis on which diabetes can affect erectile function by increasing reactive oxygen species, forming advanced glycation end products (AGEs) and activating protein kinase C pathway. Consequently, impaired vasorelaxation, enhanced vasoconstriction, nitrergic neural degeneration and structural and functional alteration of cavernosal integrity have been observed in subjects with diabetes. Furthermore, significant hypogonadism often exists in diabetic men, further complicating the understanding of diabetic ED. The treatment of diabetic ED is multimodal. Adequate control of hyperglycemia and comorbidities is prerequisite for the application of various treatments. The type 5 phosphodiesterase inhibitors (PDE5Is) are the mainstay of oral treatment of ED. Vacuum erection device and intracavernosal injection are still viable option when the treatment of PDE5I has failed. Patients with irreversible damage of the erectile mechanism are candidates for penile prosthesis implantation. Current concepts suggest that therapeutic prospects on the horizon include gene therapy, growth factor therapy and novel pharmacotherapies such as anti-AGE drugs. Conclusions: The current understading of diabetic ED is far from being satisfactory to offer adequate treatment. Future strategies in the evolution of the treatment of diabetic ED are aimed at correcting or treating underlying mechanisms.

탄두 개발의 CAE 활용

박관진 대한기계학회 2010 기계저널 Vol.50 No.4

응급실에 내원한 폐결핵환자에서 행려환자와 일반환자와의 임상적 비교

박관진,송경준,신상도,박창배,홍기정,신종환,김유진,정진희,강창우 대한응급의학회 2012 大韓應急醫學會誌 Vol.23 No.6

Purpose: We compared characteristics and outcomes of pulmonary tuberculosis in homeless and non-homeless patients. Methods: A retrospective, cross-sectional study was conducted in a Seoul municipal medical center between January 2007 and December 2011. All adult patients diagnosed with pulmonary tuberculosis were included. We classified these patients into homeless and non-homeless and compared the disease characteristics, risk factors, mortality,treatment completion rate, and resistance rate. Results: All 157 patients were diagnosed with pulmonary tuberculosis (75 homeless and 82 non-homeless). Most homeless patients were male (97.3%) and had higher emergency medical service (EMS) use (77.3%). Additionally,most homeless patients used alcohol l(76%) and smoked (77.3%). When compared with the non-homeless group, the homeless group had a higher in-hospital mortality rate (14.7%; adjusted odds ratio (OR), 4.69; 95% confident interval (CI), 1.03-21.34), and were more likely to be admitted for (adjusted OR=3.27(1.07-9.97)), but not to complete tuberculosis treatment (adjusted OR=9.10(2.24-36.98)). Conclusion: Pulmonary tuberculosis showed higher mortality in homeless than non-homeless patients. Additionally,homeless had a lower treatment completion rate and fewer resistant microorganisms.

장요근의 신장운동과 근력운동이 만성요통환자의 요부 정적유연성과 통증강도에 미치는 영향

박관진,Park, Kwan-Jin 대한물리치료과학회 2009 대한물리치료과학회지 Vol.16 No.1

Background: The purpose of this study was to investigate the effect of stretching and strengthening exercise on the static flexibility and pain intensity for the iliopsoas muscle, which is one of the main reasons for the chronic low back pain. Methods: The subjects of this study were 15 male adult patients with showed 6 score or higher in the visual analogue scale(VAS) and complained of low back pain over three months who visited department of the physical therapy, KIA motors Industrial Health Center, from October, 2008 through December, 2008. Fifteen subjects were trained stretching, mat exercises and sling exercises for iliopsoas muscle at 4-5 times a week for 4 weeks. I measured the changes on the extensibility of iliopsoas muscle, static flexibility of low back and VAS between pre- and post exercise treatment. Date were analyzed using the Wilcoxon's signed rank test considering the size of the samples. Results: 1. The angle of the hip joint that showed the extensibility of iliopsoas muscle was relieved, which was significant statistically (p<.05). 2. The static flexibility was statistically significantly improved in the trunk flexion test, trunk extension test and Schober-Test (p<.05). 3. The VAS showed decrease, which is significant statistically (p<.05). Conclusion: It is believed that the exercise treatment of iliopsoas muscle has the significant effects on the improvement of static flexibility and decrease of pain intensity for the chronic low back pain patients.

미세수술 기법을 이용한 저위서혜부 정계정맥류제거술

박관진,김수웅,백재승 大韓泌尿器科學會 1999 Korean Journal of Urology Vol.40 No.3

실데나필 투약으로 발기능 회복 이후의 투약 중단 원인

박관진,손환철,신재욱,임대정,김수웅,백재승 대한남성과학회 2004 The World Journal of Men's Health Vol.22 No.1

야뇨증의 병태생리: 뇌, 수면장애 그리고 정신적 효과

박관진,Park, Kwan-Jin 대한소아신장학회 2012 Childhood kidney diseases Vol.16 No.1

The relationship between central nervous system (CNS) and enuresis has not been sufficiently elucidated despite the presence of several circumstantial evidences. Contrary to common belief, polysomnographic sleep analysis revealed that the disturbance of arousal rather than deep sleep was responsible for enuresis. Subsequent studies confirmed depressed sympathetic tone and retarded brainstem reflex indicating abnormal arousal threshold in enuretics. In accordance with the bladder-brain dialogue, chronic stimulation of bladder may modify the brainstem function elevating arousal threshold. Epidemiological studies have suggested the association between enuresis and various psychosomatic disorders like attention deficit hyperactivity disorder (ADHD), which has shown the abnormal brainstem reflex similar to enuresis. Taken together, CNS is assumed to play a crucial role in the pathogenesis of enuresis. Psychological assessment is vital to understand the psychodynamic effect of enuresis. Studies have shown that the prevalence of psychological problems was higher in enuretic children and externalization of the symptoms was usually found. Several explanations have been brought up regarding the development of enuresis and psychological problems. Enuresis may cause psychological problems and vice versa. Otherwise, both may be associated with other variables, such as socioeconomic status (SES).