8-Bit Microcomputer 개발을 위한 시험 소자 ( 1 ) ( A Test Device for the Development of an 8-Bit Microcomputer ( 1 ) )

문규,유영주,신현종,강진영,이철동 대한전자공학회 1982 대한전자공학회 학술대회 Vol.1982 No.1

하부위장관 : 장 결핵 진단에 있어서 QuantiFERON(R)-TB Gold Test의 유용성

문규,백창희,장희철,허창,김현식 대한소화기학회 2007 대한소화기학회 추계학술대회 Vol.2007 No.-

내시경 소견으로 진단된 아메바성 대장염의 임상 양상

문규,박종범,백창희,허창,장희철,김현식,박영희,이중달 대한대장항문학회 2006 Annals of Coloproctolgy Vol.22 No.6

Purpose: Nowadays, with improvements in hygiene and in the sewage system, the prevalence of amebic colitis in Korea is declining. However, amebic colitis still occurs every year. We investigated the clinical features of current patients with amebic colitis and compared the results with those for a past endemic period in Korea. Methods: From June 2000 to June 2005, 10 patients were diagnosed in the Digestive endoscopy center of Song Do colorectal hospital as having amebic colitis. We evaluated their medical histories, clinical characteristics, and colonoscopic findings. Results: The male-to-female ratio was 1.5:1. The mean age was 38.4± 11.4 years. The mean diagnostic period from occurrence of symptoms to diagnosis was 20.4±17.5 days. The clinical symptoms of amebic colitis were diarrhea (80%), bloody stool (70%), mucoid stool (60%), abdominal pain (50%), fever, weight loss, nausea, and fatigue. Seven patients (70%) had a history of travel, and six of those seven patients had taken trips abroad. The foreign areas of travel included India (50%), Indonesia (28.6%), and Japan (16.7%). The diagnostic methods were colonoscopic biopsies to detect trophozoites of Entameba histolytica (90%) and serologic tests for the anti-ameba antibody (10%). The most common colonic locations of the lesions were the cecum (80%) and the rectum (80%). Another was the ascending colon (30%); pan-colonic involvement was also seen (10%). Conclusions: In the past, the cause of amebic colitis in Korea was poor hygiene. Nowadays, however, travel to amebiasis-endemic areas may be the most important cause. Therefore, the travel history of diarrheal patients is an important diagnostic factor in cases of amebic colitis and a differential diagnosis factor in cases of inflammatory bowel disease.

An Incidental Asymptomatic Dieulafoy’s Lesion in the Colon -A Case Report-

문규,박종범,장희철,허창,백창희,김현식 대한대장항문학회 2008 Annals of Coloproctolgy Vol.24 No.1

A Dieulafoy’s lesion is an uncommon, but important, cause of gastrointestinal bleeding. It is associated with massive, life-threatening hemorrhage and is typically difficult to diagnose. Although originally described in the stomach and rarely found below the proximal stomach, identical lesions have been reported in other gastrointestinal organs, including the duodenum, jejunum, colon, and rectum. Most cases occur with bleeding in the gastrointestinal tract. However, we present an incidental asymptomatic Dieulafoy’s lesion in the colon, which was treated successfully by using an endoscopic hemoclipping technique.

일반 여성의 감각처리 특성에 따른 섭식 태도의 차이

문규란,이춘엽,주아영,곽나임,곽나임,정혜림 대한감각통합치료학회 2020 대한감각통합치료학회지 Vol.18 No.1

목적 : 일반 여성의 감각처리 특성에 따른 섭식 태도의 차이를 확인하였다. 연구방법 : 241명의 일반 여성을 대상으로 청소년/성인 감각프로파일(Adolescent/Adult Sensory Profile; AASP)과 섭식 태도 검사(Eating Attitude Test; EAT-26)를 이용하여 설문조사를 실시하였다. 감각 처리 특성에 따른 섭식 태도는 독립표본 t-검정과 일원배치분산분석(one-way ANOVA)을 사용하여 분석하였고, 사후분석은 Scheffe Test를 실시하였다. 결과 : 감각처리 특성 중 등록저하와 섭식 통제, 감각회피와 폭식 및 음식몰두를 제외하면, 감각처리 특성에 따라 섭식 태도는 모두 유의한 차이가 나타났다(p<.05). 등록저하가 대부분의 사람보다 (매우) 많은 경 우 거식과 폭식 및 음식몰두의 태도가 부정적인 것으로 나타났고, 감각추구가 대부분의 사람과 유사하거 나 (매우) 많은 경우 모든 섭식 태도가 부정적인 것으로 나타났다. 감각민감성이 대부분의 사람보다 (매 우) 많은 경우 폭식 및 음식몰두의 태도가 부정적인 것으로 나타났으며, 감각회피가 대부분의 사람보다 (매우) 많은 경우 거식의 태도가 부정적인 것으로 나타났다. 결론 : 감각처리 특성에 따라 섭식 태도에 차이가 있었으며, 이를 토대로 일반 여성들의 섭식 태도를 조절 하기 위한 하나의 방안으로 감각통합 중재를 제안할 수 있다. Objective : This study was conducted to confirm general differences in eating attitudes according to the sensory processing characteristics of women. Methods : The Adolescent/Adult Sensory Profile (AASP) and the Eating Attitude Test (EAT-26) were used to survey 241 women. Their eating attitudes according to the sensory processing characteristics was analyzed using an independent t-test and one-way ANOVA, and the post-analysis was performed using the Scheffe test. Results : Among the sensory processing characteristics, except for eating control due to low registration, binge-eating and foodlessness due to sensory avoidance, all eating attitudes were significantly different according to sensory processing characteristics (p<.05). The anorexic behaviour, binge-eating and foodlessness was shown to be negative in cases of those who had much lower registration than most people. All eating attitudes, such as anorexia, binge-eating and foodlessness, and eating control, were shown to be negative in cases of women whose sensation seeking was equal to or much greater than the general population. The binge-eating and foodlessness were shown to be negative in cases of high sensory sensitivity. The anorexic behaviour was shown to be negative in cases of elevated sensory avoidance. Conclusion : Eating attitudes differed depending on the sensory processing characteristics. As such, sensory integration mediation can be proposed as a method of controlling the eating attitudes of women in general.

Total Knee Replacement를 시행한 환자 중 Standing Knee Lateral 검사 시 Device 사용의 유용성에 관한 고찰

홍성권,이동희,김병기,문규오,이민우,김순배 대한영상의학기술학회 2011 대한영상의학기술학회 논문지 Vol.2011 No.-

Anti-inflammatory and Neurotrophic 2H-1-Benzopyran Derivatives of Chaenomeles sinensis

하영준,이태현,Lalita Subedi,김혜령,문규리,Sun Yeou Kim,김충섭 한국생약학회 2022 Natural Product Sciences Vol.28 No.1

Two 2H-1-benzopyran derivatives, methyl 8-hydroxy-2,2-dimethyl-2H-1-benzopyran-5-carboxylate (1) and methyl 8-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-carboxylate (2), including a new compound (1) were isolated from the twigs of Chaenomeles sinensis. Their chemical structures were characterized based on analysis of NMR data including 1H and 13C, COSY, HSQC, and HMBC and HRMS data. The isolated compounds (1 and 2) were assessed for their anti-neuroinflammatory activity by measuring inhibition levels of nitric oxide (NO) production in lipopolysaccharide (LPS)-activated BV-2 cells and for their neurotrophic activity by the secretion of nerve growth factor (NGF) in C6 cells. Compounds 1 and 2 exhibited powerful anti-neuroinflammatory effects with IC50 values of 17.14 and 19.30 μM, respectively, without cell toxicity, and also showed moderate effects on the stimulation of NGF secretion levels with 113.15 ± 3.54 and 130.20 ± 8.03%, respectively. The biosynthetic pathway of 1 and 2 was proposed that they would be derived from a protocatechuic acid and an isoprenyl unit.

투시조영 검사에서의 면적선량의 측정 및 비교 : 식도조영, 상복부위장관조영, 연하조영 중심으로

노현아(Hyun A Noh),조한영(Han Yeong Cho),문규오(Kyoo O Moon),손순룡(Soon Lyong Son) 대한영상의학기술학회 2009 대한영상의학기술학회 논문지 Vol.2009 No.-

Purpose : This thesis is, esophagography, UGI series, swallowing study using DAP meter measure in checking and fluoroscopy time, body weight, to learn about the correlation with image number, compared with earlier studies and seek the ways of reducing the radiation dose. Materials and Methods : October- December 2008 was an experiment of 212 patients. Philips has used its equipment, DAP meter adherent in front of X-ray tube calibration, and using the ion-chamber. By checking the patients weight, fluoroscopy time, image number and DAP values were measured. Results : According to the increase in esophagography fluoroscopy time as an increase in the DAP had paid attention to statistics (P<0.05). In UGI series, according to the increase in weight, fluoroscopy time, image number as an increase in the DAP had paid attention to statistics (P<0.05). In swallowing study, fluoroscopy time and DAP had paid attention to statistics (P<0.05). In all test, depending on the increase in fluoroscopy time also DAP had increased gradually. In case of our hospital, the average DAP and fluoroscopy time with advanced studies to compare at least 2.4 times, respectively, 6.5 times as high was investigating. In UGI series, fluoroscopy time at least 1.7 times, DAP 2.6 times, image number also was 2.4 time higher. Conclusion : To reduce patient dose for fluoroscopy examination, in here and now, they should evaluate patient dose and accurately analyze related factors of exposure dose. It comes to the conclusion that patient dose is reduced in good image quality by perfonning the examinations for reference of advanced studies or recommend dose recommended dose in international organizations.

마이크로카테터와 조영제의 아이오다인 함유율 변화에 따른 조영제 카테터 통과시간의 상관성 분석

서영득(Young-deuk Seo),권호석(Ho-seok Kwon),이훈섭(Hun-seob Lee),문규오(Gyu-oh Mun) 대한인터벤션영상기술학회 2020 대한인터벤션영상기술학회지 Vol.23 No.1

목적: 마이크로 카테터와 조영제 아이오다인 함유율에 따른 조영제 카테터 통과시간(Catheter Transit Time;CTT)의 상관성을 분석하고, Achived psi의 변화 및 Flow Rate를 측정, 비교하여 조영제를 이용한 시술 시에 조영제 자동주입기(Auto injector)로 인해 발생되는 오류를 줄이고. 완전한 주입이 되지 않아 발생하는 화질저하 및 재촬영을 방지하여 시술시에 참고 값을 제시하고자 하였다. 재료 및 방법: 요오드 함유율이 다른 3종류의 조영제(Visipaque320, Visipaque270, Bonorex 240)와 6종류의 마이크로카테터(2.2Fr, 2.0Fr, 1.98Fr, 1.9Fr, 1.7Fr, 1.7Fr)를 조영제 자동주입기를 이용해, 조영제 카테터 통과시간의 상관성을 분석하고, Archived psi, flow rate를 측정,비교하였다. 결과: 6종류의 마이크로카테터 모두 조영제 농도에 따른 카테터 조영제 통과시간 차이는 통계적으로 유의한 음의 상관성을 보였다. A사 2.2Fr 마이크로카테터는 –0.867, B사 2.0Fr 마이크로카테터는 –0.982, C사 마이크로카테터는 –0.898, D사 1.9Fr 마이크로카테터는 –0.960, B사 1.7Fr 마이크로카테터는 –0.861, C사 1.7Fr 마이크로카테터는 –0.868의 음의 상관성을 나타냈다. 조영제의 온도변화는 통계적으로 유의한 차이를 나타내지 않았다. (P>0.5) 결론 : 동일한 마이크로카테터에서 조영제의 요오드 함유율이 높을수록 조영제 자동주입기에서 표시되는 Achived psi가 높게 측정되거나, 마이크로 카테터 종류에 따라 완전한 주입이 이루어지지 않았다. 따라서 본 연구를 바탕으로, 시술시에 적절한 마이크로카테터와 조영제의 사용은 안정성과 효율성을 높여 합병증을 줄일수 있고, 불필요한 피폭이나 조영제 과다사용을 줄일 수 있을 것이다. Purpose: The appropriate use of microcatheter with automated contrast injector could reduce complications by reducing radiation exposure time and contrast media. The purpose of this study was to investigate the effect of contrast media concentration and microcatheter size on catheter transit time in an in-vitro study. Material & method: A comparison study to investigate catheter transit time, archived psi, and flow rate was performed using six microcatheter with different viscosities, Visipaque320 , Visipaque270, and Bonorex240 with Automated Contrast Injector. Result: Six microcatheter were negative correlation, according to contrast media viscosities. A Company 2.2Fr microcatheter was –0.867, B Company 2.0Fr micro catheter was –0.982, C Company microcatheter was –0.898, D Company 1.9Fr microcatheter was –0.960, B Company 1.7Fr microcatheter was –0.86. Company 1.7Fr microcatheter was –0.868 negative correlation. There was no difference according to contrast media concentration. Conclusion : When compared with the same microcatheter, The higher the contrast medium concentration of contrast medium. Achived psi was measured higher according to microcatheter, it was found that the complete injection was not appropriate. Therefore, Based on this study, Appropriate selection microcatheter and contrast agents is likely to improve safety and efficacy related angiography procedure.

방사선투시장비를 사용한 검사에 참여하는 소화기내과 소속 간호사들의 의료용 방사선에 대한 의식도 조사

황민호(Min Ho Hwang),조한영(Han Yeong Cho),문규오(Kyoo O Moon),엄준용(Joon Yong Uhm),손순룡(Soon Lyong Son),박철수(Cheol Soo Park) 대한영상의학기술학회 2010 대한영상의학기술학회 논문지 Vol.2010 No.-

Purpose : To purpose of this study is to research on consciousness of gastro-intestinal nurses who work in radiation area for ERCP, PTCS, Enteroscopy, Colon stent examination. Materials and methods : This is intended for full-time twenty nurse(male 2, female 18). The research were used 5-point scale survey about radiation basic knowledge, behavior during examination, exposure management and attended a radiation education. We analyzed relationship between period of examination, age, exposure time and radiation consciousness. We also analyzed relationship between radiation basic knowledge, behavior, management and radiation consciousness using SPSS ver 12. Results : Total average consciousness was 3.92 point, total raditaion knowledge level was 3.59 point, total behavior level was 3.79 point and total radiation safety management level was 4.66 point. Female nurse has high level radiation consciousnes rather than male nurse. Radiation consciousness has nothing to relationship with period of examination, age of nurse and exposure time during examination. Everybody did not attend a radiation education. Twelve people do not knows about a radiation education. Six people could not attend due to overtime work Two of them did not attend due to disinclination. Conclusion : Management about radiation exposure of gastro-intestinal nurses is very well but their radiation basic knowledge is lower compare with average radiation consciousness. The reason for this is lack of education of medical radiation. Therefore, we should make effective and realistic education project about medical radiation for gastro-intestinal nurses.