‘보육실습’ 관련 연구동향 분석 연구

류은미 한국아동부모학회 2016 아동부모학회지 Vol.2 No.1

본 연구는 '보육실습’관련 논문의 동향을 분석하여 앞으로의 연구 방향을 제시하고자 하였 다. 이를 위해 2003년 1월부터 2016년 6월 현재까지 국내 학술지에 발표된 보육실습 관련 논 문 41편을 대상으로 연구시기, 연구목적, 연구방법, 연구대상에 대하여 분석을 실시하였다. 첫째, 보육실습 관련 연구는 2009년에 8편으로 가장 많이 연구되었고 2005년에 0편으로 가장 적게 연구되었으며, 보육실습 기준이 더욱 강화되는 최근에 증가하는 추세를 보이고 있다. 둘째, 보육실습 관련 연구의 목적은 의미탐색을 목적으로 한 연구가 가장 많았고 프로그램 개발과 원인 파악을 목적으로 하는 논문이 가장 적게 나타났으며, 보다 다양한 목적의 연구 가 골고루 수행되어야 할 것이 요청되었다. 셋째, 보육실습 관련 연구의 방법은 질적 연구가 양적연구보다 더 많이 수행됨으로써, 양적연구 또한 중요하게 수행되어야 함이 요청되며, 지 금까지 수행되어 온 질적 연구의 결과들이 앞으로 보육실습의 방향을 제시하는데 충실하게 반영되어야 함을 시사해 준다. 넷째, 보육실습 관련 연구의 대상은 예비교사를 대상으로 한 연구로 편중되어 있어서, 보육실습을 둘러싼 중요한 인적 환경인 실습지도교사, 원장, 교수 등을 대상으로 한 연구가 보다 많이 수행되어야 함이 요청된다 This study aims to suggest future research directions based on the analysis of the current research trends in relation to child care practices. Thus, 41 researches about child care practices were analyzed which were published in journals form January 2003 to June 2016 in Korea in the field. These studies were analyzed according to research frequency, purpose, method, and subject. First, researches on child care practices were studied most intensely in 2009 and there was none in 2005. specifically focused on nursery. Because the standards of child care practices are being strengthened nowadays, recent researches on child care practices tend to be increased. Second, in terms of research purpose, studies mostly dealt with the investigation of the meanings of child care practices. There were the least number of researches whose purposes were to develop a program or to find out the cause of its failures. Third, to mention their research method, qualitative researches outnumber the quantitative ones. Still, quantitative researches are also important, and the results of qualitative studies, carried out so far, should be utilized faithfully to provide a direction for future child care practices. Fourth, main subjects for the researches have been concentrated on the pre-service teachers. So, more studies should be actively carried out on the various important parties of child care practices such as practice guidance teachers, directors, professors.

화재 피해를 입은 건축물의 안전성 평가 지침에 관한 방향 및 내용

류은미,이유진,신영수 한국화재소방학회 2018 한국화재소방학회 학술대회 논문집 Vol.2018 No.춘계

DNCB로 유도된 아토피성 피부염 생쥐에서 탄닌산 도포가 피부 LCE1 유전자 발현에 미치는 영향

류은미,이병래 대한미용학회 2019 대한미용학회지 Vol.15 No.4

The purpose of the present study was to examine the effects of tannic acid (TA) on late cornified envelope 1(LCE1) gene expression in the skin of atopic dermatitis mice. Atopic dematitis was induced in BALB/c mice by repeated application of 1-chloro-2,4-dinitrobenzene (DNCB) on the shaved back skin of the mice. The experimental group was divided into 4 groups, viz. control group, olive-acetone group, DNCB group and DNCB+TA group. The DNCB+TA group displayed improved dermatitis skin symptoms, such as rashes, papules, and eczema in comparison with the DNCB group. In the DNCB+TA group, the dermatitis symptoms such as rash, papule and eczema improved compared with the DNCB group. Histological findings in the DNCB group showed that the stratum corneum was destroyed, the layers of keratinocytes were thickened, and distinction between the dermis and epidermis was not clear. Compared to the DNCB group in DNCB+TA group, the stratum corneum was preserved and the distinction between the dermis and epidermis could be clearly observed. The cornified envelope constituent proteins lec1a1, lec1a2, lec1b, lec1d, lec1e, lec1f, lec1g, lec1i and lec1l increased the gene expression in DNCB group, and the expressions of these genes became reduced in DNCB+TA group. These results showed that TA has certain effect in improving atopic dermatitis, which in turn signified the potential of TA as a remedy to improve atopic dermatitis. In this regard, further studies on the mechanism of action and stability of TA in the improvement effect are needed.

탄닌산이 DNCB에 의해서 유도된 아토피성 피부염 유사병변의상피 분화에 미치는 영향

류은미,이정인,이병래 대한미용학회 2018 대한미용학회지 Vol.14 No.4

This study examined the effects of tannic acid on the epidermal differentiation of atopic dermatitis (AD). AD-like skin lesions were induced in BALB/c mice by repeated application of 1-chloro-2,4-dinitrobenzene (DNCB) to the shaved skin of animal backs. Animals tested were divided into 4 groups: i) controls, and those treated with ii) olive-acetone, iii) DNCB and iv) DNCB+tannic acid. In the DNCB+tannic acid group, dermatitis symptoms (eg, rash, papule and eczema) were improved compared with the DNCB group. The results of skin histology revealed that stratum corneum was not observed in the DNCB group, but was observed in the DNCB+tannin group. In the skin of the DNCB group, Sprr1b, Sprr2e, Sprr2f, Casp14, and Kik5 protein expression was higher and Foxn1 and Elf5 protein expression was lower when compared with the control group. In the skin of the DNCB+tannin group, the expression of Sprr1b, Sprr2e, Sprr2f, Casp14 and Klk5 proteins were lower, while the expression of Foxn1 and Elf5 proteins were higher when compared with the DNCB group. When compared with the control group, the expression of Krt6a, krt6b and krt16 proteins in the skin was increased in the DNCB group, while it was decreased in the DNCB+tannic acid group. These result suggested that tannic acid may improve symptoms of DNCB-induced dermatitis. Changes in the expression of Sprr1b, Sprr2e, Sprr2f and Casp14, Klk5, Foxn1 and Elf5 proteins in the skin following treatment with tannic acid seem to be closely related to the improvement of skin inflammatory symptoms. Further studies are needed to elucidate the mechanism mediating changes in the expression of keratinocyte differentiation-related genes following treatment with tannic acid. 본 연구는 탄닌산이 아토피성 피부염 개선에 미치는 영향을 관찰하기 위하여 DNCB 피부염이 유발된 생쥐에 탄닌산을 경구 투여한 결과 다음과 같은 결론을 얻었다. 피부 조직학적 소견에서 DNCB군은 각질층이 떨어져 나가 보이지 않았고, DNCB+탄닌군은 DNCB군 피부조직과 비교하면 표피 최외측에 각질층이 보존되어 있어서 피부염 완화에 의한 결과로 추측된다. DNCB군의 피부 각질구성 단백질인 Sprr1b, Sprr2e 및 Sprr2f와 분화관련 효소 Casp14나 Klk5는 발현이 증가되고, 각질세포 분화과정을 조절하는 전사인자 Foxn1과 Elf5는 유전자 발현이 감소되었다. DNCB+탄닌군은 DNCB군에 비하여 피부 각질구성 단백질인 Sprr1b, Sprr2e 및 Sprr2f와 분화 관련 효소 Casp14나 Klk5은 발현이 감소되고, 각질세포 분화과정을 조절하는 전사인자 Foxn1과 Elf5는 유전자 발현이 증가되었다. 피부 케라틴을 구성하는 Krt6a, krt6b 및 krt16은 DNCB군에서 유전자 발현이 증가되었고, DNCB+탄닌산군에서는 유전자 발현이 감소되었다. 이상의 실험결과로서 탄닌산을 경구투여하면 DNCB 피부염의 증상이 개선되었는데 이는 각질 형성세포의 분화과정에서 각질을 구성하는 단백질인 Sprr1b, Sprr2e 및 Sprr2f와 분화 관련 효소 Casp14와 Klk5 유전자 발현변화와 각질세포 분화과정을 조절하는 전사인자 Foxn1과 Elf5 유전자 발현의 변화와 밀접한 연관이 있음을 확인할 수가 있었다. 결론적으로 탄닌산은 아토피성 피부의 증상으로 볼 수 있는 피부 발진, 구진 및 습진 등의 증상을 개선하는데 도움을 줄 수 있어 문제성 두피나 피부관련 화장료의 기초적인 자료로서 활용가치가 있을 것이다. 또한, 본 연구를 바탕으로 탄닌산에 의한 각질구성 단백질과 분화관련 효소 및 전사인자의 유전자 발현 변화의 원인이나 기전을 규명하기 위해서는 추가적인 연구가 필요할 것으로 사료된다.

현대건축의‘전통’해석방식에 관한 연구 : ‘하버마스와 가다머의 해석학 논쟁’을 바탕으로 based upon‘Hermeneutic Debate between Gadamer and Habermas’

류은미,강훈,이동언 대한건축학회 2004 대한건축학회논문집 Vol.20 No.7

Under the influence on Modernism, Korean modern architecture had a tendency to pursue not creativity but materiality. Although the architectural concern about the tradition increases, traditional Korean architectural language was not still positively reactivated. Therefore, this paper architecturally rethinks of that situation through ‘Hermeneutics Debate between Gadamer and Habermas’. In reactivating the tradition, the former has the limitation of dependence on absolute power of the past as pre-understanding and the latter has the possibility of combining both the realistic rationality and the original meanings of the tradition. The final goal of this paper is to suggest an architectural discourse based upon the reactivation of tradition by Gadamer's main concept "fusion of horizons" and by Habermas‘ "controlled distancing".

C57BL/6 마우스에서 꽃송이버섯 추출물의 에틸 아세테이트층과 물층의 분리에 따른 발모 효과

류은미,신현재 한국피부과학연구원 2011 대한피부미용학회지 Vol.9 No.4

Sparassis crispa is an edible and medicinal mushroom, which commonly called ‘cauliflower mushroom’. S. crispa is known to be good sources of food and nutraceuticals due to their rich flavors and β-glucan contents as well as antiviral and anticancer compounds. C57BL/6 mice, the widely used lab mouse strain, were used in this animal study because of their availability and a similar hair growth cycle to human hair. Herein, hair-removed five-year-old C57BL/6 mice were used to examine the effect of S. crispa extracts for 70% ethanol extract, ethyl acetate extract, and water extract on hair growth stimulation. The extracts and control compounds were topically treated once a day for 4 weeks. The hair growth was photographically and histologically examined during the total period of 4 weeks. Overall, hair growth of S. crispa water extracts test group was stimulated compared to ethyl acetate extract and 70% extract, along with positive control (3% minoxidil) and negative control (normal). The whole study showed a significant improvement of hair growth effect of S. crispa extracts. This findings suggests that S. crispa extract has a hair growth promoting activity, but more works should be planned to elucidate the hair growth mechanism.

원두커피 부산물 첨가에 따른 밀싹의 성장과 엽록소 성분의 변화

류은미,최환석,신현재 한국생물공학회 2014 KSBB Journal Vol.27 No.2

Wheat sprout (Triticum aestivum) shows excellentnutritional and health effects due to the contents in aminoacids, minerals, and other nutrients rich in chlorophyll andvitamins. In this study, spent coffee grounds were used to cultivatethe wheat sprout for 12 day. An amount of 0%, 20%,40%, 60%, 80%, and 100% (w/w, based on commercial sterilesoil media) spent coffee grounds were used under the sameconditions. Total length and weight of wheat sprout, aboveandbelow-ground length and weight, and the chloropyll contentswere compared. Soil media were analyzed before andafter wheat cultivation, showing that 40% and 60% (w/w)coffee media promoted wheat growth in view of length andweight. Chlorophyll contents in each group showed almostconstant values, while 100% (w/w) coffee media led to aslight decrease. In conclusion, spent coffee grounds stimulatedwheat growth, showing nearly stable contents of chlorophyll.

Rapidly Growing Bilateral Pseudoangiomatous Stromal Hyperplasia of the Breast

류은미,황인용,장은덕 대한영상의학회 2010 Korean Journal of Radiology Vol.11 No.3

A tumoral pseudoangiomatous stromal hyperplasia (PASH) that causes huge breast enlargement is very rare. Only two cases of huge tumoral PASHs have been reported in the English medical literature. We report here on a surgically confirmed case of bilateral huge tumoral PASH in a 47-year-old woman, and we present the imaging and histopathology findings. We also review the relevant medical literature.

꽃송이버섯 추출물이 제모된 C57BL/6 마우스의 모발성장 및 억제에 미치는 영향

류은미,신현재,나명순 한국피부과학연구원 2010 대한피부미용학회지 Vol.8 No.4

Sparassis crispa is an edible and medicinal mushroom, which commonly called the cauliflower mushroom. S. crispa is known to be a good source of food and nutraceuticals due to their rich flavors and β-glucan contents as well as a good source of antiviral and anticancer compounds. However, there have been no report on the effect on hair growth stimulation and/or growth inhibition. C57BL/6 mice the most widely used lab mouse strain were used in this animal study due to their availability and the similar hair growth cycle to human hair. In this study, hair-removed five-year-old C57BL/6 mice were used to examine the effect of S. crispa extracts(70% ethanol) on hair growth stimulation and inhibition of the mice. The extracts and control compounds were topically treated once a day for 4 weeks. The hair growth was photographically and histologically examined during the total period of 4 weeks. Hair growth of the test group was a little inhibited compared to positive (3% minoxidil) and negative control groups (water and ethanol treated groups), respectively. The whole data showed little improvement of hair growth effect of S. crispa extracts but with no real statistical significance. These results suggest that S. crispa extract has little hair growth promoting activity and more works should be done to elucidate the inhibition mechanism. 본 연구는 최근 면역 및 항암활성 등 혈류 개선과 관련된 약리적 효과로 주목받고 있는 꽃송이버섯 추출물이 발모․양모 및 제모에 어떠한 영향을 미치는지 알아보고자 실험동물을 통하여 실험적 연구를 수행하였다. 실험은 실험군의 꽃송이버섯 추출물과 대조군의 무시료, 에탄올 70%, 버섯추출물, 미녹시딜 3%로 나누어 실험동물 C57BL/6 mouse(female)에 처리하였다. 실험시료에 따라 실험군과 대조군으로 나누어 총 5군을 실험에 이용하였다. 7주령 mouse의 등판을 제모한 뒤 4주(28일)동안 시료에 따른 양모효과를 육안적 관찰하였고, 경피 적출 후 조직학적인 검사를 수행하여 다음과 같은 결과를 얻었다. 1. 털의 성장정도를 알아보기 위한 mouse 외형의 육안적 관찰결과, 실험군인 꽃송이버섯 추출물이 대조군의 버섯추출물, 에탄올, 무시료, 미녹시딜 보다 모발의 성장이 억제됨이 관찰되었다. 2. 4주(28일)째 mouse를 경추 도살하여 얻은 피부조직의 모낭형태를 광학현미경으로 관찰한 결과, 실험군인 꽃송이버섯 추출물에서 대조군에 비해 모낭조직의 길이가 짧고 피부 위쪽에 위치하고 있었으며, 모낭내의 모근이 짧게 성장하여 피부의 표면으로 자라는 모낭 형태를 하고 있었다. 결론적으로 꽃송이버섯 추출물을 C57BL/6 mouse(female)의 등부위에 처리한 결과, 육안적 외형분석 및 조직학적 분석에서 실험군이 대조군보다 모발 성장이 억제되는 것으로 나타남에 따라 실험군인 꽃송이버섯 추출물은 모발 성장억제 효과가 있는 것으로 사료된다.

반복화재에 노출된 건축구조용 고성능 특수형강의 구조적 거동에 대한 연구

류은미,안재권,신동진,여인환 대한용접·접합학회 2023 대한용접학회 특별강연 및 학술발표대회 개요집 Vol.2023 No.5