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자궁경부의 Glassy cell carcinoma 2예
김기태,김현찬,김우경,허윤근,류문철,민유선 대한부인종양 콜포스코피학회 1994 Journal of Gynecologic Oncology Vol.5 No.4
Glassy cell carcinoma is a histologic subtype of cervical cancer with distinct pathologic features and it has an aggressive biologic course. It was first described by Glucksmann and Cherry in 1956 as a poorly differentiated adenoquamous carcinoma and commented on its poor prognosis, unresponsiveness to traditional modes of therapy, and often associated with pregnancy. The characteristic histologic features are defined as follows: 1) cells with a moderate amount of cytoplasm resembling ground glass, 2) a fairly distinct cell membrane that stains with eosin or PAS, 3) large nuclei with prominent nucleoli. We present two cases of glassy cell carcinoma of the cervix successfully treated by neoadjuvant chemotherapy and radical hyterectorny, with a brief review of literatures.