버스 운전직 근로자들의 감정노동이 직무 스트레스에 미치는 영향

김희량,김희걸,이윤정,이금재 한국직업건강간호학회 2014 한국직업건강간호학회지 Vol.23 No.1

지역사회 거주 후기노인의 칩거에 영향을 미치는 요인: 일상생활수행능력이 독립인 노인을 중심으로

김희량,고영,한송이 한국장기요양학회 2023 장기요양연구 Vol.11 No.3

본 연구는 지역사회에 거주하는 후기노인을 대상으로 칩거에 영향을 미치는 요인을 파악하기 위한 서술적 연구이다. 2019년 9월부터 12월까지 일 보건소에서 방문건강관리서비스를 받은 일상생활이 독립인 노인 241명을 대상으로 자료를 수집하여 분석하였다. 칩거에 영향을 미치는 요인은 Χ2-test, t-test, 위계적 로지스틱 회귀분석을 이용하여 분석하였다. 본 연구에서 후기노인의 칩거율은 23.7%였다. 칩거에 영향을 미치는 요인을 확인한 결과, 도구적 일상생활능력이 의존인 경우(OR=3.04, 95% CI: =1.31-7.05), 복용 약물 수가 많을수록(OR=1.30, CI: =1.03-1.64), 소셜 네트워크 서비스를 이용한 교류가 없는 경우(OR=5.51, CI: =1.12-27.19)가 후기노인의 칩거율이 높아지는 것으로 확인되었다. 따라서 후기노인의 칩거예방을 위해서는 신체적 기능 유지와 만성질환의 관리가 중요하다. 또한, 가까운 친구, 이웃과 교류할 수 있는 기회를 제공하고 노인의 스마트폰을 이용한 교류를 늘릴 수 있는 교육적 지원이 필요하다.

Extensive characterization of feline intra-abdominal adipose-derived mesenchymal stem cells

김희량,이지현,변정수,구나연,이지윤,조인수,차상호 대한수의학회 2017 Journal of Veterinary Science Vol.18 No.3

Mesenchymal stem cells (MSCs) isolated from various tissues have been well characterized for therapeutic application to clinical diseases. However, in contrast to MSCs from other animal species, the characteristics of feline MSCs have not been fully documented. In this study, we conducted extensive characterization of feline adipose tissue-derived MSCs (fAD-MSCs). Study fAD-MSCs were individually isolated from the intra-abdominal adipose tissues of six felines. The expression levels of cell surface markers and pluripotent markers were evaluated. Next, proliferation capacity was analyzed by performing cumulative population doubling level (CPDL) and doubling time (DT) calculation assays. Differentiation potentials of fAD-MSCs into mesodermal cell lineages were analyzed by examining specific staining and molecular markers. All fAD-MSCs positively expressed cell surface markers such as CD29, CD44, CD90, CD105, CD166, and MHC-I, while CD14, CD34, CD45, and CD73 were negatively expressed. The CPDL of the fAD-MSCs was maintained until passage 5 to 6 (P5 to P6), whereas DT increased after P3 to P4. Also, stem cell-specific pluripotent markers (Oct3/4, Nanog, and SSEA-4) were detected. Importantly, all fAD-MSCs demonstrated mesodermal differentiation capacity. These results suggest that fully characterized fAD-MSCs could be beneficial when considering the use of these cells in feline disease research.

광중합기의 광도와 시간에 따른 글래스 아이오노머의 치수내 온도변화

김희량,이형일,이광원,이세준 대한치과보존학회 2001 Restorative Dentistry & Endodontics Vol.26 No.5

When cavity floor is near the pulp, polymerization of light-activated restorations results in temperature increase. this temperature increase cause by both the exothermic reaction process and the energy absorbed during irradiation. Therefore instating base is reqired. Most frequently used insulating base is glass ionmer. The purpose of this study was to evaluate intrapulpal temperature changes of glass ionomer according to various curing intensity and curing time. Caries and restoration-free mandibular molars extracted within three months were prepared Class I cavity of 3×6mm with high speed handpiece. 1mm depth of dentin was evaluated with micrometer in mesial and distal pulp horns. Pulp chambers were filled with 37.0±0.1℃ water to CEJ. Chromium-alumina thermocouple was placed in pulp horn for evaluating of temperature changes. Glass ionomer material was placed in 2mm. total curing time was 40s ; continuous 40s, intermittent 20s, intermittent 10s. Glass ionomer material was cured with 300mW/㎠, 550mW/㎠ light curing unit. The results were as follows : 1.Temperature in pulp increased as curing unit power is increased. 2.Temperature in pulp more increased continuous emission than intermittent emission. Key words : Sealing ability, Retrograde filling material

지역사회 거주 노인의 활동 특이적 균형자신감에영향을 미치는 요인

김희량,고영 한국지역사회간호학회 2018 지역사회간호학회지 Vol.29 No.4

Purpose: The purpose of this study is to identify factors influencing activities-specific balance confidence in community- dwelling older adults. Methods: This is secondary analysis of data from an intervention study for improving cognitive function. The data were collected from March 2 to September 30, 2017 at a senior center. Data of 131 older adults were included for this secondary analysis, and were analyzed by using t-test, ANOVA, and multiple regression. Results: The mean score of activities-specific balance confidence is 65.08 out of a possible range of 0-100. The significant factors affecting activities-specific balance confidence among old adults include ‘more than 85 years old’, ‘waist circumference’, ‘depressive symptoms’, ‘activity restriction due to fear of falling’, and ‘self-rated health’ which explained 52.8% of the variance. Conclusion: The study results indicate that psychologic factors as well as physical condition should be considered for interventions to increase activities-specific balance confidence.

내 · 외과 간호사의 근거기반 통증사정 및 관리 가이드라인 수행도

김희량(Kim, Heui Lyang),송지은(Song, Chi Eun),소향숙(So, Hyang Sook) 한국성인간호학회 2016 성인간호학회지 Vol.28 No.5

Effect of moisture on sealing ability of root canal filling with different types of sealer through the glucose penetration model

Jang, Jin-Ah,Kim, Hee-Lyang,Her, Mi-Ja,Lee, Kwang-Won,Yu, Mi-Kyung 大韓齒科保存學會 2010 Restorative Dentistry & Endodontics Vol.35 No.5

Objectives: To compared the effect of different levels of moisture of root canal on the sealing ability after filling with four different types of sealer. Materials and Methods: Single-rooted teeth (n = 90) instrumented to and apical size of 0.06 / 45 were randomly assigned to 12 experimental groups (n = 7 per group), positive/negative control groups (n = 3 per group). The teeth of the experimental groups (a. DRY; b. PAPER POINT DRY; c. WET) were obturated with sealer (Group 1-3: Sealapex; Group 4-6: AH plus; Group 7-9: Tubuli-seal; Group 10-12: EndoRez) and warm vertical compaction method. After 7 days in 37˚C, 100% humidity, the coronal-to-apical microleakage was evaluated quantitatively using a glucose leakage model. The leaked glucose concentration was measured with spectrophotometer at 1, 3, 7, 14, 21, and 30 days. Data were recorded ad mmol/L and statistically analysed with the two-way ANOVA and Duncan test (p = 0.05). Results: Throughout the experimental period Tubuli-seal/WET (Group 9) showed the highest mean cumulative glucose penetration (178.75 mmol/L), whereas AH plus/DRY (Group 4) had the least (20.78 mmol/L). Conclusions: The results of this study demonstrated that the moisture condition of root canals at the time of obturation and the type of sealer that was used had a significant effect on leakage and sealing ability. Thus drying procedure according to sealer types is a critical step and should not be missed in endodontic treatment. 연구목적: 본 연구의 목적은 수종의 sealer를 이용하여 각기 다른 양의 잔여수분이 존재하는 근관을 충전 시, 근관충전의 sealing ability를 glucose leakage model로 평가하는 것이다. 연구 재료 및 방법: 발치된 90개의 단근치를 치관부를 잘라내고 #45 / 0.06 taper까지 확대한 후, 12개의 실험군 (n = 7)과 2개의 대조군 (n = 3)으로 나누었다. 실험군을 3가지 습윤 상태에서 (a, DRY; b, PAPER POINT DRY; c, WET) 4종류의 sealer로 (Group 1-3: Sealapex; Group 4-6: AH plus; Group 7-9: Tubuli-seal; Group 10-12: EndoRez), warm vertical compaction method를 이용해 충전하였다. 37˚C, 습도 100%에서 7일 동안 보관하고 glucose leakage model을 이용하여 치관부로부터 치근부 방향의 미세누출을 정량화하였다. 1, 3, 7, 14, 21, 30일 째 누출된 glucose의 농도를 spectrophotometer로 측정하였다. 결과: 관찰기간 동안 AH plus/DRY군 (Group 4)이 12개 그룹 중 가장 적은 양의 leakage를 보였다 (20.78 mmol/L). 반면에 Tubuli-seal/WET군 (Group 9)이 12개 그룹 중 가장 높은 양의 leakage를 보였다 (178.75 mmol/L). 결론: 본 연구의 결과는 충전 시 근관 내의 습윤 상태와 sealer 종류가 microleakage에 유의한 영향을 미친다는 것을 입증하였다. 그러므로 sealer 종류에 따라 각기 다른 근관 건조 방법을 사용하는 것이 근관치료에서 더 좋은 결과를 얻을 수 있는 방법일 것이다.

Effects of Multifactorial and Follow-up Programs Applying a Capacity Building Strategy: Focusing on Older Adults Living in a Urban-rural Complex Area

한송이,고영,김희량,김지연 한국지역사회간호학회 2019 지역사회간호학회지 Vol.30 No.2

Purpose: The purpose of this study is to examine effects of a multifactorial program for preventing the frailty of older adults and effects of a follow-up program applying a capacity building strategy. Methods: A quasi-experimental pretest-posttest design was used for the nonequivalent control group. The follow-up group (n=75) and non-follow-up group (n=68) received the same multifactorial program comprising muscle strength exercise, cognitive training, and psychosocial programs for 12 weeks. After completion of multifactorial program, the follow-up group took follow-up programs applying the capacity building strategy for following 12 weeks. The data of physical function, cognitive function, and psychological function, and self-rated health were collected from both groups three times: before intervention, after intervention, and 12 weeks after intervention. The data were analyzed using x2 test and t-test. Results: In comparison with the non-follow-up group, the scores of Timed Up & Go Test, and physical activities energy expenditure were significantly improved in the follow-up group. Conclusion: These results indicate that a multifactorial program with follow-up adapting the strategies of capacity building for the older adults group is feasible to prevent the physical frailty in community.

Canine mesenchymal stem cells immunomodulate atopic dermatitis through the induction of regulatory T cells in an ex vivo experimental study

변정수,이제니,이경빈,김희량,구나연,조인수,차상호,김도형 한국예방수의학회 2016 예방수의학회지 Vol.40 No.1

Mesenchymal stem cells (MSCs) are multipotent stem cells, which can be induced to differentiate into several cells. MSCs are also reported to possess immunomodulatory properties through secretion of inflammatory cytokines and generation of regulatory T (Treg) cells. Treg cells play an important role in allergic disorders, including atopic dermatitis. We examined the immunomodulatory effects of canine adipose tissue derived-MSCs (cAD-MSCs) in 3 groups: Group 1, untreated normal dog; Group 2, dogs with Dermatophagoides farinae ointment-induced atopic dermatitis; and Group 3, dogs with atopic dermatitis. Canine peripheral blood mononuclear cells (PBMCs) were collected from each group and co-cultured with cAD-MSCs. After co-culturing, PBMCs were separated and the expression of Treg cells was examined by flow cytometry. According to the results, the populations of Treg cells were increased in 3 ex vivo experimental groups, co-cultured with cAD-MSCs. These results would be important for the application of MSCs in clinical trials.

모듈식 자동 방사성핵종 테크니튬-99 분리기 운영 프로그램 개발

권용태,정근호,최상도,강문자,이완로,김희량,최근식,이창우 한국방사성폐기물학회 2008 한국방사성폐기물학회 학술논문요약집 Vol.6 No.2