기계적 자극에 대한 백서 치주인대 섬유아세포의 변화

김태균,김창성,조규성,채중규,김종관,최성호,Kim, Tae-Gyun,Kim, Chang-Sung,Cho, Kyoo-Sung,Chai, Jung-Kiu,Kim, Chong-Kwan,Choi, Seong-Ho 대한치주과학회 2001 Journal of Periodontal & Implant Science Vol.31 No.2

Periodontal disease is characterized by inflammation and subsequent loss and/or damage to tooth-supporting tissues such as bone, cementum,and periodontal ligament. Periodontal ligament and cementum are the key tissues in the initial process of regeneration following periodontal disease. Therefore, studies on cementoblasts, which form cementum are emphasized. It is still unclear which cells cementoblast differentiate from. This study was conducted under the hypothesis that PDL fibroblast can differentiate into either cementoblast or osteoblast depending on the conditions of surrounding tissue. Clinically, with excessive traction force of orthodontic appliances or excessive occlusion hypercementosis is observed, and this has been confirmed histologically. Consequently, activation of cementoblast can be expected in rats when mechanical stimuli are given to PDL fibroblast. Therefore, the purpose of this article is to prove that PDL fibroblast differentiates into cementoblast in rats under mechanical stimuli using histologic and molecular methods. In this study, twenty rats were given hard diet. Ten of them were sacrificed after 1 week, and the others were sacrificed after two weeks. Slides were made from tooth specimen, and they were studied under the microscope. In addition, PDL fibroblast and cementum from the extracted teeth were analyzed with Northern blotting. In histologic examination, as time passed, PDL fibroblast migrated to the dentin side, differentiated into cementoblast, and formed new cementum. In Northern blotting, it was found that mRNA expression of cementoblast-specific proteins such as BSP, OC, OPN, and type I collagen were more prominent in rats sacrificed after 2 weeks of hard-diet than rats sacrificed after 1 week. From these findings we can conclude that PDL fibroblast can differentiate into cementoblast under mechanical stimuli. We think that 'Rat Models' used in this study will be beneficial to future studies regarding cementoblast.

방재연구 - 기후변화를 고려한 시설별 방재기준 가이드라인 개발

김태균,Kim, Tae-Gyun 한국방재협회 2013 방재저널 Vol.15 No.4

몬테카를로 위치추정 알고리즘을 이용한 수중로봇의 위치추정

김태균,고낙용,노성우,이영필,Kim, Tae-Gyun,Ko, Nak-Yong,Noh, Sung-Woo,Lee, Young-Pil 한국전자통신학회 2011 한국전자통신학회 논문지 Vol.6 No.2

본 논문에서는 몬테 카를로 방법을 사용한 수중로봇의 위치추정 방법을 제안한다. 수중로봇의 위치추정은 자율 주행을 위한 기본 기능의 하나이다. 제안된 알고리즘에 의하면 추측항법(데드 레크닝 방법)의 약점인 위치 오차 누적 문제를 해결할 수 있다. 제안된 방법은 확률적인 방법으로 로봇 동작의 불확실성과 센서 정보의 불확실성을 처리한다. 특히 칼만 필터 방법과 달리, 로봇의 비선형 운동 특성과 센서의 비가우시안 출력 분포 특성을 모델링할 수 있다. 본 논문에서는 수중로봇 위치 추정에 몬테카를로 위치추정(Monte Carlo Localization : MCL, 이하 MCL로 표기함) 알고리즘을 적용하기 위하여 오일러각을 이용하여 모션모델을 구하였다. 또한 수중로봇에 모션모델과 센서모델을 적용하여 시뮬레이션을 구현하고, 이를 통해 수중로봇에 MCL 알고리즘의 적용 가능성을 보였다. The paper proposes a localization method of an underwater robot using Monte Carlo Localization(MCL) approach. Localization is one of the fundamental basics for autonomous navigation of an underwater robot. The proposed method resolves the problem of accumulation of position error which is fatal to dead reckoning method. It deals with uncertainty of the robot motion and uncertainty of sensor data in probabilistic approach. Especially, it can model the nonlinear motion transition and non Gaussian probabilistic sensor characteristics. In the paper, motion model is described using Euler angles to utilize the MCL algorithm for position estimation of an underwater robot. Motion model and sensor model are implemented and the performance of the proposed method is verified through simulation.

수종 생약재의 간염 B형 바이러스 증식 억제 활성 검색

김태균,한형미,강석연,정기경,김승희,Kim, Tae-Gyun,Han, Hyung-Mee,Kang, Seog-Youn,Jung, Ki-Kyung,Kim, Seung-Hee 한국생약학회 1999 생약학회지 Vol.30 No.3

This study was undertaken to test for anti-hepatitis B virus (HBV) activity of the aqueous extracts prepared from 9 medicinal plants of Korea (Cornus officinalis, Caesalpinia sappan, Rubus coreanus, Lycium chinense, Artemisia capillaris, Isatis tinctoria, Phyllanthus urinaria, Lysimachia christinae, Lonicera japonica). Aqueous extracts were tested for cytotoxicity and assayed for inhibition of HBV replication by measurement of HBV DNA and surface antigen (HBsAg) levels in the extracellular medium f HepG2 2.2.15 cells. The extract from Rubus coreanus, Artemisia capillaris, Phyllanthus urinaria decreased the levels of extracellular HBV virion DNA at concentrations ranging from 128 to $256\;{\mu}g/ml$ and inhibited the production fo HBsAg dose-dependently without showing cytotoxicity. Our findings suggest that these three hebal medicinal plants may have potential to develop as specific anti-HBV drugs in the future.

동맥경화유발 토끼와 형질전환 마우스에서 산마늘 추출물의 항동맥경화 효과

김태균,김승희,강석연,정기경,최돈하,박용복,류종훈,한형미,Kim, Tae-Gyun,Kim, Seung-Hee,Kang, Soeg-Youn,Jung, Ki-Kyung,Choi, Don-Ha,Park, Yong-Bok,Ryu, Jong-Hoon,Han, Hyung-Mee 한국생약학회 2000 생약학회지 Vol.31 No.2

Atherosclerosis is emerging as one of the major causes of death in Korea as well as Western societies. In the present study; hypocholesterolemic and antiatherogenic effects of the ethanol extract of Allium victorialis Makino was investigated using the conventional rabbit and the cholesteryl ester transfer protein (CETP)-transgenic mouse model. Hypercholesterolemia was induced by feeding high cholesterol diet to the animals for 30 days and they were then fed with high cholesterol diet containing 0.5% of the A. victorialis extract for additional 30 (or 40) days. In the experiment using rabbits, treatment with the A. victorialis extract significantly decreased plasma total cholesterol, low density lipoprotein (LDL)-cholesterol, triglyceride levels and lipid peroxidation compared to those in the control group. Total cholesterol contents in the liver and the heart were also significantly decreased. Lipid staining of the aorta isolated from the rabbits showed that treatment with the A. victorialis extract decreased formation of atheromatous plaques on the intima of the aorta. In the experiment employing CETP transgenic mouse model, treatment with the A. victorialis extract decreased the levels of plasma total cholesterol and the tissue triglyceride levels in the heart. These results demonstrated that the ethanol extract of A. victorialis lowered serum cholesterol levels, tissue lipid contents and accumulation of cholesterol in the artery.

표준.시험인증 기술 동향 - 케이블 방송망에서의 전송기술 표준화 동향

김태균,Kim, Tae-Gyun 한국정보통신기술협회 2014 TTA저널 Vol.152 No.-

하악과두의 골증식체 평가에 있어서 transmaxillary 촬영법과 transcranial 촬영법의 비교

김태균,김진수,Kim Tae Gyun,Kim Chin Soo 대한영상치의학회 1989 Imaging Science in Dentistry Vol.19 No.1

5개의 건조두개골의 하악과두에 인위적으로 골증식체를 형성한 후 수직각 25°, 수평각 0°를 부여한 transcranial 촬영법과 두부규격 방사선 촬영기를 이용한 transmaxillary 촬영법을 시행하여 얻은 90매의 transcranial 및 45매의 transmaxillary방사선사진을 통해 다음과 같은 결론을 얻었다. 1. transcranial 촬영법에서 골증식체가 하악과두의 상중부에 있을 때 폐구시에 관찰이 용이하였으나 (p<0.05), 그 이외의 부위에서는 통계학적인 유의성이 없었다(p>0.05). 2. 골증식체가 하악과두의 내부 및 중부 (p<0.05)에 위치하였을 때는 transmaxillary 촬영법에서 관찰이 더 용이하였으며 외부에 위치하였을 때는 통계학적인 유의성이 없었다 (p>0.05). 3. 골증식체가 하악과두의 상방(p<0.05) 및 후방(p<0.01.)에 위치하였을 때는 trans maxillary 촬영법에서 관찰이 더 용이하였으며 전방에 위치하였을 때는 통계학적인 유의성이 없었다. (p>0.05). 4. Transcranial 촬영법에서는 골증식체가 하악과두의 측방으로 위치할수록(p<0.01), transmaxillary 촬영법에서는 후방으로 위치할수록(p<0.35) 관찰이 용이하였다. The purpose of this study was to decide the diagnostic value of transmaxillary and transcranial projection in the evaluation of mandibular condyles. Five dry skulls with intact anatomic structure were selected for this study and the artificial osteophytes were attached to 9 different are as of the mandibular condyle. Ninety transcranial and forty-five transmaxillary radiographs were taken and then the radiographs were evaluated three times. The results were as follows; In transcranial radiographs, superocentral osteophyte was easily observed in closing state than in opening state (p<0.05). But there were no significant differences in other locations (p>0.05). The osteophytes on the medial and central portion easily observed at the transmaxillary projection than transcranial projection (p<0.05), but there was no significant difference on the lateral portion (p>0.05). The osteophytes on the superior (p<0.01) and posterior (p<0.01.) portion were easily observed at the transmaxillary projection than transcranial projection, but there was no significant difference on the anterior portion (p >0.05). The more laterally located osteophytes (p<0.01) at the transcranial projections were easily observed. The more posteriorly located osteophytes (p<0.05) at the transmaxillary projections were easily observed.

새로운 사상체질 설문지의 임상적 활용에 관한 연구

김태균,김종원,Kim, Tae-gyun,Kim, Jong-weon 사상체질의학회 2000 사상체질의학회지 Vol.12 No.1

1. 연구목적 본 연구(硏究)의 목적은 체질진단분류의 간편화와 정확화를 위해 만들어진 새로운 사상체질(四象體質) 변증설문지(辨證說問紙)의 임상적 활용도를 알아보기 위한 것이다. 2. 연구방법 이 연구(硏究)를 위하여 동의의료원 건강검진센터를 방문한 환자 및 일반 학생 등 총 306명을 대상으로 설문지(說問紙)를 작성하였다. 작성된 설문지(說問紙)를 이용하여 아홉 가지 판별식을 만들었으며 이 아홉 가지 판별식을 이용하여 자료의 체질(體質)를 분석하여 그 결과를 얻었다. 3. 연구결과 1. 판별식(I)로 A군 대상자의 체질(體質)를 판별한 결과 소음인(少陰人) 진단정확률이 58.97%, 태음인(太陰人) 진단될 정확율이 51.43%, 소양인(少陽人) 진단 정확률이 45.16%로 나타났다. 판별식(I-1)은 소음인(少陰人) 진단정확률이 62.50%, 태음인(太陰人) 진단정확률이 52.94%, 소양인(少陽人) 진단정확률이 45.16%로 상승시켰다. 판별식(I-2)은 소음인(少陰人) 진단정확률이 60.53% 태음인(太陰人) 진단정확률이 52.78% 소양인(少陽人) 진단정확률이 48.39%로 상승시켰다. 2. 판별식 (II)으로 B군 대상자의 체질(體質)을 판별한 결과 소음인(少陰人) 진단정확률이 68.25% 태음인(太陰人) 진단정확률이 37.93%, 소양인(少陽人) 진단정확률이 38.20%로 나타났다. 판별식(II-1)은 소음인(少陰人) 진단정확률이 68.25%, 태음인(太陰人) 진단정확률이 41.38%, 소양인(少陽人) 진단정확률이 39.32%로 약간 상승시켰다. 판별식(II-2)은 소음인(少陰人) 진단정확률이 66.66%, 태음인(太陰人) 진단정확률이 41.73%, 소양인(少陽人) 진단정확률이 38.20%로 거의 변화가 없었다. 3. 판별식(III)으로 C군 대상자의 체질(體質)를 판별한 결과 소음인(少陰人) 진단정확률이 62.86%, 태음인(太陰人) 진단정확률이 35.87%, 소양인(少陽人) 진단정확률이 32.22%로 나타났다. 판별식(III-1)은 소음인(少陰人) 진단정확률이 62.86%, 태음인(太陰人) 진단정확률이 36.95%, 소양인(少陽人) 진단정확률이 32.22%로 거의 변호가 없었다. 판별식(III-2)은 소음인(少陰人) 진단정확률이 61.47%, 태음인(太陰人) 진단정확률이 34.44%, 소양인(少陽人) 진단정확률이 31.82%로 거의 변화가 없었다. 이상의 결과로 볼 때 판별식(I-2)이 가장 좋은 결과가 나왔으며, 몇 가지 문제점을 보완한다면, 임상에서 활용할 수 있는 보다 나은 판별식을 구할 수 있을 것으로 사료된다. 1. The purpose of study The purpose of study is The New Sasang Constitution Questionnaire to improve clinical right, as the person takes off uncomfortable to must use both Questionnaire of Sasang Constitution Classification II (QSCC) and Questionnaire of Sasang Classification(I) 2. The method of study I made the judgmental equation, increasing ability of judgment to give thinking importance among each subject about a Clinical study of judgment and the method of using, I investigated which Equation is better by a Clinical Study of the judgment. I made Equation, 9 and examine the Accuracy rate of the judgment through patients, student of University formal peoples and peoples taking the drugs 304 member totally. 3. The result of study I made 9 Equation of the judgment. The Equation of the judgment(I-2) is the highest ability of the judgment, the diagnostic accuracy is 60.53% about Soeum, 52.78% about Taeum, 48.39 about Soyang.

우주 주권시대 개막 '10주년'

김태균,Kim, Tae-Gyun 한국정보통신집흥협회 2005 정보화사회 Vol.176 No.-

PSS 튜닝을 위한 기본 연구 PART II : PSS 실계통 최적 정수 선정을 위한 튜닝기법

김태균,신정훈,윤용범,김동준,문영환,백영식,Kim, Tae-Gyun,Sin, Jeong-Hun,Yun, Yong-Beom,Kim, Dong-Jun,Mun, Yeong-Hwan,Baek, Yeong-Sik 대한전기학회 2000 전기학회논문지A Vol.49 No.7

Based on the results in the first-part paper, PSS tuning methods including the determination of PSS gain and compensation of phasor lagging are investigated in this second part. In the phase compensation, PSS should compensate phase lagging, resulted from power system-generator-excitation system loop, to provide damping torque in equal phase with the generator speed. Also, PSS gain should be determined to provide maximum damping torque as much as possible without the other modes unstable. In this paper, gain tuning method using the root-locus and the phase compensation of PSS at the one machine with infinite bus system are presented. The differences between PSS tuning at the tuning condition and at the least-stable condition are also discussed.