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0.5% Bupivacaine을 이용한 척수마취시 마취제의 비중이 마취효과에 미치는 영향
김창열,윤석화,김혜자,최세진 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.1
Effects of solutions of 0.5% bupivacaine, containing different concentrations of dextrose (0%, 0.5%, 0.8%, 1%, 3%, 5%, 8%) were studied after intrathecal injection in seven (Group A-Group G) groups of 15 patients. The results are summarized as follows: 1. The mean specific gravity of solutions was 1.0065, 1.0087, 1.0092, 1.0094, 1.0152, 1.0198 and 1.0314 (Group A-Group G). These values are isobaric (Group A, B), hyperbaric (Group E, F, G), and slightly hyperbaric (Group C, D) compared to cerebrospinal fluid at 25℃. 2. The mean maximum level of sensory block was increased according to the increment of specific gravity of the solutions. But no significant differences between Group A and B, Group C and D, Group E, F, and G. 3. The mean time of sensory block to T11 was decreased according to the increment of specific gravity of the solutions. 4. The mean time to the expected level (T4) of sensory block at given dosage of each solution was 25.7, 18.4, 9.7 minutes(Group E, F, G, respectively). 5. Complete motor block of the legs was rapid according to the increment of specific gravity of the solutions.
Nitric Oxide Detection of Fe(DTC)3-hybrizided CdSe Quantum Dots Via Fluorescence Energy Transfer
김창열 한국분말재료학회 2022 한국분말재료학회지 (KPMI) Vol.29 No.6
We successfully synthesize water-dispersible CTAB-capped CdSe@ZnS quantum dots with the crystal size of the CdSe quantum dots controlled from green to orange colors. The quenching effect of Fe(DTC)3 is very efficient to turn off the emission light of quantum dots at four molar ratios of the CdSe quantum dots, that is, the effective covering the surface of quantum dots with Fe(DTC)3. However, the reaction with Fe(DTC)3 for more than 24 h is required to completely realize the quenching effect. The highly quenched quantum dots efficiently detect nitric oxide at nano-molar concentration of 110nM of NO with 34% of recovery of emission light intensity. We suggest that Fe(DTC)3-hybridized CdSe@ZnS quantum dots are an excellent fluorescence resonance energy transfer probe for the detection of nitric oxide in biological systems.